UA94055C2 - Substituted benzimidazoles and methods of preparation - Google Patents

Substituted benzimidazoles and methods of preparation

Info

Publication number
UA94055C2
UA94055C2 UAA200802593A UAA200802593A UA94055C2 UA 94055 C2 UA94055 C2 UA 94055C2 UA A200802593 A UAA200802593 A UA A200802593A UA A200802593 A UAA200802593 A UA A200802593A UA 94055 C2 UA94055 C2 UA 94055C2
Authority
UA
Ukraine
Prior art keywords
methods
compositions
kinase
compounds
preparation
Prior art date
Application number
UAA200802593A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Мина Э. Айкава
Пеймен Амири
Джеффри Х. Доув
Барри Гаскелл Левайн
Кристофер Макбрайд
Тереза Э. Пик
Дениэл Дж. Пун
Савитри Рамурти
Пол А. Ренхоув
Синтия Шафер
Деррин Стюарт
Шарадха Субрамениан
Original Assignee
Новартис Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Новартис Аг filed Critical Новартис Аг
Publication of UA94055C2 publication Critical patent/UA94055C2/en

Links

Abstract

New substituted benzimidazole compounds of formula (I), compositions, and methods of inhibition of kinase activity associated with tumorigenesis in a human or animal subject are provided. In certain embodiments, the compounds and compositions are effective to inhibit the activity of at least one serine/threonine kinase or receptor tyrosine kinase. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a serine/threonine kinase or receptor tyrosine kinase mediated disorder, such as cancer.(I),
UAA200802593A 2005-08-30 2006-08-30 Substituted benzimidazoles and methods of preparation UA94055C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71253905P 2005-08-30 2005-08-30

Publications (1)

Publication Number Publication Date
UA94055C2 true UA94055C2 (en) 2011-04-11

Family

ID=39956007

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200802593A UA94055C2 (en) 2005-08-30 2006-08-30 Substituted benzimidazoles and methods of preparation

Country Status (4)

Country Link
CN (1) CN101253168B (en)
ES (1) ES2360608T3 (en)
UA (1) UA94055C2 (en)
ZA (1) ZA200800506B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102336740B (en) * 2010-07-27 2013-07-24 中国科学院上海药物研究所 Novel imidazole compound and its application
BR112013012485A2 (en) * 2010-11-19 2016-09-06 Glaxosmithkline Ip No 2 Ltd braf inhibitor treatment method
TW201722957A (en) * 2015-09-15 2017-07-01 葛蘭素史克智慧財產（第二）有限公司 Chemical compounds

Also Published As

Publication number Publication date
ZA200800506B (en) 2009-11-25
CN101253168B (en) 2012-12-12
ES2360608T3 (en) 2011-06-07
CN101253168A (en) 2008-08-27

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