UA93522C2 - 2-amino-7,8-dihydro-6h-pyrido[4,3-d] pyrimidin-5-ones - Google Patents

2-amino-7,8-dihydro-6h-pyrido[4,3-d] pyrimidin-5-ones

Info

Publication number
UA93522C2
UA93522C2 UAA200805390A UAA200805390A UA93522C2 UA 93522 C2 UA93522 C2 UA 93522C2 UA A200805390 A UAA200805390 A UA A200805390A UA A200805390 A UAA200805390 A UA A200805390A UA 93522 C2 UA93522 C2 UA 93522C2
Authority
UA
Ukraine
Prior art keywords
pyrido
pyrimidin
dihydro
amino
compounds
Prior art date
Application number
UAA200805390A
Other languages
Russian (ru)
Inventor
Тимоти Д. Мачажевски
Синтия M. Шафер
Кристофер Макбрайд
Уильям Антониос-Маккри
Брендон M. Доугхен
Барри Г. Левайн
Йи Ксиа
Морин Маккенна
K. Майкл Вонг
Крис Менденхолл
Йашин Жоу
Баоквинг Гонг
Дан Гу
Джон Долан
Джон Тулински
Кристин Бриннер
Женхай Гао
Ксиаодонг Лин
Абран Косталес
Элис Рико
Натан Браммеиер
Тереза Пик
Дениэл Пун
Пол A. Барсанти
Пол A. Ренхоув
Original Assignee
Новартис Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Новартис Аг filed Critical Новартис Аг
Publication of UA93522C2 publication Critical patent/UA93522C2/en

Links

Abstract

Disclosed are 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, their stereoisomers, tautomers, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, either alone or in combination with at least one additional therapeutic agent. Disclosed also are methods of using the 2-anuno-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of cellular proliferative, viral, autoimmune, cardiovascular, and central nervous system diseases.
UAA200805390A 2005-09-30 2006-09-28 2-amino-7,8-dihydro-6h-pyrido[4,3-d] pyrimidin-5-ones UA93522C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72279605P 2005-09-30 2005-09-30

Publications (1)

Publication Number Publication Date
UA93522C2 true UA93522C2 (en) 2011-02-25

Family

ID=40059303

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200805390A UA93522C2 (en) 2005-09-30 2006-09-28 2-amino-7,8-dihydro-6h-pyrido[4,3-d] pyrimidin-5-ones

Country Status (6)

Country Link
CN (1) CN101287734B (en)
AR (1) AR110068A2 (en)
SI (1) SI1928875T1 (en)
SV (1) SV2008002856A (en)
UA (1) UA93522C2 (en)
ZA (1) ZA200803658B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010034670A2 (en) * 2008-09-26 2010-04-01 INSERM (Institut National de la Santé et de la Recherche Médicale) Host cell kinases as targets for antiviral therapies against hcv infection
CN102227221A (en) * 2008-11-28 2011-10-26 诺瓦提斯公司 Pharmaceutical combination containing hsp90 inhibitor and mtor inhibitor
MX2011005671A (en) * 2008-11-28 2011-06-20 Novartis Ag Pharmaceutical combinations comprising a pyrido [4, 3-d] pyrimidine derived hsp90-inhibitor and a her2 inhibitor.
CN107624113B (en) * 2015-05-04 2020-10-23 豪夫迈·罗氏有限公司 Tetrahydropyridopyrimidines and tetrahydropyridopyridines as inhibitors of HBsAg (HBV surface antigen) and HBV DNA production for the treatment of hepatitis B virus infection
CN109846886A (en) * 2019-03-26 2019-06-07 中国医学科学院基础医学研究所 Purposes of the NVP-HSP990 in the drug of preparation treatment epilepsy
CN114681463B (en) * 2022-04-29 2024-03-15 暨南大学 Application of HSP990 in preparing medicine for preventing and/or treating adenovirus infection

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6165873A (en) * 1984-09-07 1986-04-04 Mitsui Petrochem Ind Ltd 2-piperazinopyrimidine derivative
US4734418A (en) * 1984-12-14 1988-03-29 Mitsui Petrochemical Industries, Ltd. Quinazoline compounds and antihypertensives
MA21177A1 (en) * 1987-02-11 1988-10-01 May & Baker Ltd CYCLIC DIONES.

Also Published As

Publication number Publication date
SI1928875T1 (en) 2011-10-28
CN101287734B (en) 2011-07-20
CN101287734A (en) 2008-10-15
SV2008002856A (en) 2008-06-30
AR110068A2 (en) 2019-02-20
ZA200803658B (en) 2009-09-30

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