TWI569847B - Positioning Method of Proton Beam in Proton Treatment Equipment - Google Patents

Description

Proton beam positioning method for proton therapy equipment

The present invention relates to a proton therapy device that emits a proton beam to treat cancer, and more particularly to a method of aligning the proton beam.

Cancer is one of the leading causes of death in humans worldwide. In addition to treatments such as tumor resection, chemotherapy, and target therapy, radiation therapy has recently been used to irradiate the site of malignant tumors (ie, cancer) with radiation. Inhibit or kill cancer cells to achieve therapeutic effects. In general, radiation therapy is performed by using a radiotherapy machine to target high-energy rays or particles to cancer tumors for external irradiation, including X-rays, gamma rays (cobalt 60), electrons, protons, and heavy particles. Since radiotherapy may kill or destroy cancer cells, it may also cause damage to normal cells in the surrounding area. Therefore, it is necessary to accurately determine the dose and position distribution of the irradiation according to the shape or position of the tumor. For example, in the Republic of China Patent Publication No. 201315507, a simulation device is disclosed which simulates a case where a charged particle beam is irradiated onto an object to be irradiated, and the charged particle beam is assumed to have a virtual shape having a conical expansion, and the derivation is utilized. An extended dose distribution core of the charged particle beam that illuminates the body simulates the dose distribution of the charged particle beam within the illuminated body. According to this, the dose distribution of the charged particle beam is calculated in advance, so that a proton beam treatment device equipped with the simulation device can be irradiated according to the dose distribution, thereby effectively improving the accuracy. However, in the general proton beam treatment device, the weight of the whole device is as high as hundreds of tons, and the nozzle for emitting a proton beam is also up to hundreds of kilograms. During use, the proton emitted may be caused by the weight. There is an offset between the beam and the set firing position, and there is a correction requirement.

SUMMARY OF THE INVENTION A primary object of the present invention is to solve the problem that a proton beam treatment device may shift a shot of a proton beam due to its own weight during use. To achieve the above object, the present invention provides a method for locating a proton beam of a proton therapy device, comprising the steps of: Step 1: providing a proton therapy device comprising a high energy proton source, and a high energy proton shot a source-connected rotating arm, a proton beam nozzle disposed on the rotating arm and interlocking with the rotating arm, and a control system electrically connected to the rotating arm and the proton beam nozzle; Step 2: commanding the rotating arm to move to a Presetting a rotating coordinate, and using an optical stereo coordinate tracking module to measure an actual rotating coordinate of the rotating arm, comparing the preset rotating coordinate with the actual rotating coordinate to obtain a mechanical error about the rotating arm Step 3: command the proton beam nozzle to emit a proton beam toward a predetermined coordinate, and measure a real coordinate of the proton beam by using a proton beam detector, and compare the preset coordinate with the actual coordinate to obtain a relevant Magnetic field error of the proton beam nozzle; and step 4: adjusting the control system according to the mechanical error and the magnetic field error, so that the rotating arm is in accordance with A first control instruction to move the rotating coordinate system after a correction, and with the nozzle of the proton beam emitted after a proper calibration of the proton beam to a second coordinate according to an instruction of the control system. In this way, the present invention uses the optical stereo coordinate tracking module to measure the actual rotational coordinate of the rotating arm to obtain the mechanical error, and then measure the actual coordinate of the proton beam by the proton beam detector to obtain the The magnetic field error, the mechanical error and the magnetic field error are used as a basis for adjusting the control system, so that the corrected proton beam emitted by the proton beam nozzle can be corrected to the correct coordinate.

The detailed description and technical contents of the present invention will now be described with reference to the following drawings: Please refer to the accompanying drawings, FIG. 1 and FIG. 3, FIG. 1 is a schematic diagram of a proton therapy device according to an embodiment of the present invention, 2 is a schematic view showing the rotation of a rotating arm according to an embodiment of the present invention, and FIG. 3 is a schematic view showing a proton beam emitted from a proton beam nozzle according to an embodiment of the present invention. As shown in the figure, the present invention is a proton beam positioning of a proton therapy device. The method comprises the following steps: Step 1: providing a proton therapy device 10, the proton therapy device 10 comprising a high energy proton source 11, a rotating arm 12 connected to the high energy proton source 11, and a rotating arm 12 and a proton beam nozzle 13 associated with the rotating arm 12 and a control system 14 electrically connected to the rotating arm 12 and the proton beam nozzle 13. Referring to FIG. 1 , the high-energy proton source 11 is a device for increasing the velocity (kinetic energy) of charged particles, and may include a cyclotron system, an energy selection system, and a Beam transport system. The rotating arm 12 is rotatable to drive the proton beam nozzle 13, and the control system 14 can set the operation of the rotating arm 12 and the proton beam nozzle 13. Step 2: Command the rotating arm 12 to move to a preset rotating coordinate C1, and use an optical stereo coordinate tracking module 20 to measure an actual rotating coordinate C2 of the rotating arm 12, and compare the preset rotating coordinates. A mechanical error associated with the rotating arm 12 is obtained after C1 and the actual rotational coordinate C2. As shown in FIG. 2, in the embodiment, the rotating arm 12 is driven by the control system 14, and the rotating arm 12 is moved around the treatment platform 40 toward the preset rotating coordinate C1. However, since the rotating arm 12 has a weight with the proton beam nozzle 13 disposed thereon, the rotating arm 12 may be displaced when moving, actually moving toward the actual rotating coordinate C2, thus utilizing The optical stereo tracking module 20 is configured to position the rotating arm 12 through a laser tracker 21, and measure the actual rotating coordinate C2 of the rotating arm 12, and then compare with the preset rotating coordinate C1. In order to obtain the mechanical error generated by the rotating arm 12 between the preset rotating coordinate C1 and the actual rotating coordinate C2, in the "FIG. 2", the optical stereo coordinate tracking module 20 is only set in the position. Without limitation, the adjustment can be made according to actual measurement requirements, and the laser tracker 21 can also be rotated according to the required detection direction. Step 3: command the proton beam nozzle 13 to emit a proton beam 131 toward a predetermined coordinate, and measure an actual coordinate of the proton beam 131 by using a proton beam detector 30, and compare the preset coordinates with the actual coordinates to obtain A magnetic field error associated with the proton beam nozzle 13. As shown in FIG. 3, the proton beam detector 30, which is movably disposed, is disposed on the proton beam nozzle 13, and the proton beam nozzle 13 is driven by the control system 14, and the proton beam nozzle 13 is set to face. The proton beam 131 is emitted in a direction D1 to be seated on the preset coordinates. However, in fact, the proton beam nozzle 13 is affected by gravity caused by its own weight and at different positions, so that the proton beam 131 is deflected when it is emitted. Moving, actually, the proton beam 131 is emitted toward the second direction D2 and is located at the actual coordinate. Therefore, the proton beam detector 30 is used to measure the actual coordinate and further compared with the preset coordinate to The magnetic field error produced by the proton beam nozzle 13 between the emission of the proton beam 131 for the preset preset coordinates and the actual coordinates of the actual seat is obtained. Step 4: Align the control system 14 according to the mechanical error and the magnetic field error, so that the rotating arm 12 moves a corrected rotational coordinate according to a first command of the control system 14, and the proton beam nozzle 13 is used in accordance with the A second command of control system 14 transmits a corrected proton beam to a correct coordinate. Herein, after the mechanical error is obtained, the control system 14 can perform calibration according to the mechanical error, for example, generating the first command as a suitable displacement of the original preset rotary coordinate C1 in a compensated manner to form After the correction, the coordinate is rotated, so that the rotating arm 12 moves according to the corrected rotating coordinate, and the control system 14 adjusts the magnetic field of the emitted proton beam 131 according to the magnetic field error to match the second command adjustment. The original direction of the proton beam 131 is emitted, and finally the proton beam nozzle 13 is caused to emit the corrected proton beam, so that the corrected proton beam is seated at the desired correct coordinate, and the positioning is completed. In summary, the present invention separately utilizes the optical stereo coordinate tracking module and the proton beam detector to respectively measure the mechanical error generated by the rotating arm and the magnetic field error generated by the proton beam nozzle, and The mechanical error and the magnetic field error are used as a basis for adjusting the control system, so that the corrected proton beam emitted by the proton beam nozzle can be accurately controlled by correcting the offset, and is located at the correct coordinate, and can be used continuously. Therefore, the present invention is highly progressive and conforms to the requirements for applying for an invention patent, and the application is filed according to law, and the praying office grants a patent at an early date. The present invention has been described in detail above, but the foregoing is only a preferred embodiment of the present invention, and is not intended to limit the scope of the invention. That is, the equivalent changes and modifications made by the scope of the present application should remain within the scope of the patent of the present invention.

10‧‧‧Proton therapy equipment
11‧‧‧High-energy proton source
12‧‧‧Rotating arm
13‧‧‧Proton beam nozzle
131‧‧‧Proton beam
14‧‧‧Control system
20‧‧‧Optical Stereo Tracking Module
21‧‧‧Laser Tracker
30‧‧‧Proton beam detector
40‧‧‧Treatment platform
C1‧‧‧Preset Rotary Coordinates
C2‧‧‧ actual rotating coordinates
D1‧‧‧ first direction
D2‧‧‧ second direction

1 is a schematic view of a proton therapy device according to an embodiment of the present invention. 2 is a schematic view showing the rotation of a rotating arm according to an embodiment of the present invention. 3 is a schematic view showing a proton beam emitted from a proton beam nozzle according to an embodiment of the present invention.

12‧‧‧Rotating arm

13‧‧‧Proton beam nozzle

131‧‧‧Proton beam

30‧‧‧Proton beam detector

D1‧‧‧ first direction

D2‧‧‧ second direction

Claims (1)

A method for positioning a proton beam of a proton therapy device comprises the following steps: Step 1: providing a proton therapy device comprising a high energy proton source, a rotating arm connected to the high energy proton source, and a setting a proton beam nozzle coupled to the rotating arm and coupled to the rotating arm and a control system electrically connected to the rotating arm and the proton beam nozzle; Step 2: commanding the rotating arm to move to a preset rotating coordinate, and utilizing a An optical stereo coordinate tracking module is configured to measure an actual rotating coordinate of the rotating arm, and compare the preset rotating coordinate with the actual rotating coordinate to obtain a mechanical error about the rotating arm; Step 3: command the proton beam The nozzle emits a proton beam toward a predetermined coordinate, and uses a proton beam detector to measure an actual coordinate of the proton beam, and compares the preset coordinate with the actual coordinate to obtain a magnetic field error related to the proton beam nozzle; Step 4: Align the control system according to the mechanical error and the magnetic field error, so that the rotating arm is moved according to a first command of the control system After the rotating coordinate to a correction, and with the nozzle of the proton beam emitted after a proper calibration of the proton beam to a second coordinate according to an instruction of the control system.