TW201501692A - Re-wearable wireless device - Google Patents

Abstract

A re-wearable wireless device includes a reusable component to be secured to a disposable component. The reusable component includes a sensor interface to receive signals from an electrode secured to a living subject and monitors physiological and physical parameters associated with the living subject and a cellular wireless communication circuit. An adhesive base the device includes a first adhesive layer and a second adhesive layer partially covering the first adhesive layer around a perimeter thereof, where the first and second adhesive layers include different adhesives. A method of establishing a link between two wireless devices is also disclosed, where a first wireless device with an insignia representing a communication channel address identification is provided. An image of the insignia is captured with a mobile telephone computing device comprising an image sensor. The captured image is processed to extract the communication channel address identification represented by the insignia.

Description

Re-wearable wireless device Mutual reference to the application

This application is part of the continuation of the application No. 13/336,956, filed on December 23, 2011, which is filed on February 12, 2010, filed on Serial No. 12/673,326. In the case of the division, the application No. 12/673,326 claims that the application of PCT/US09/68128, filed on December 15, 2009, is based on the benefit of US 371, and claims that the application of No. 61/122,723 on December 15, 2008 The interests of the application claim the interests of the provisional application No. 61/160,289 filed on March 13, 2009, and claim the interest of the provisional application No. 61/240,571 filed on September 8, 2009, claiming October 2009 The benefit of the provisional application No. 61/251,088 filed on the 13th, the disclosure of which is hereby incorporated by reference.

The present invention generally relates to a re-wearable wireless device. More specifically, the present invention relates to a wearable wireless device configured to monitor at least one parameter and wirelessly communicate at least one parameter that is monitored to a communication network. The communication network will be monitored via a communication network or other wide area network. At least one parameter is communicated to a remote device, such as a backend server. At least one parameter to be monitored may include skin impedance, electrocardiogram signal, conductive transmission current signal, wearer position, temperature, heart rate, perspiration rate, humidity, altitude/pneumatic pressure, global positioning system (GPS), proximity Other physiological and physical parameters such as bacterial content, glucose level, chemical labeling, blood oxygen concentration, etc., but are not limited thereto.

Use low-power wireless communication protocols that then transmit data collected on remote servers via wired connections, plain old telephone services (POTS), cellular data, etc., for example, Bluetooth, Bluetooth low power consumption Bluetooth low energy (BLE), wireless transmission module (ZigBee), ANT, exclusive, etc., the current wearable wireless device architecture communicates with hubs, base stations, and phones. The new mobile chip allows for the combination of cellular modems/telephones in personal wireless wearable devices, simplifying overall system design/enhanced usability while reducing service costs.

Other topics related to current wearable wireless devices include the high cost of manufacturing electronic components, user discomfort associated with long wear-type adhesive portions or portions in contact with the skin, and the like.

A wearable wireless device is provided in a medium facing system. The wearable wireless device includes a reusable component configured to Fixed to a disposable component. The reusable component includes a sensor interface configured to receive signals from at least one electrode configured to be secured to the living body and to monitor one or more physiological and physical parameters associated with the living body, and is reusable The assembly also includes a cellular wireless communication circuit.

In another aspect, an adhesive substrate for a wearable wireless device is provided. The wearable adhesive substrate comprises a first adhesive layer and a second adhesive layer, and the second adhesive layer partially covers the first adhesive layer around the periphery of the first adhesive layer. The first adhesive layer includes a first adhesive, and the second adhesive layer includes a second adhesive.

In another aspect, a method of establishing a connection between two wireless devices is provided. According to this method, a first wireless device is provided having a flag indicating a communication channel address identification. The image of the logo is captured by a mobile phone computing device containing an image sensor. The captured image is processed to extract the communication channel address identification represented by the flag.

Still further, the re-worn wireless device in accordance with the present invention includes a reusable component and a disposable component. Reusable components can include a mobile wafer set, an energy source, a sensor, and the like. The disposable assembly can include an electrode and/or an adhesive for adhering the disposable component to the skin of a living being of a human or animal. The disposable assembly can include at least two types of adhesives.

100‧‧‧Wireless system

102‧‧‧Reshaptable wireless devices

104‧‧‧ Living

106‧‧‧Remote node (remote server)

108‧‧‧Hive Communication Network

110‧‧‧Other networks

112‧‧‧Internet

114‧‧‧Mobile Signal Tower

116‧‧‧Base Station (BS)

118‧‧‧Database

120‧‧‧Processing system

202‧‧‧Disposable components

204‧‧‧Reusable components (reusable electronic modules)

206‧‧‧(RF) wireless communication circuit

208‧‧‧Sensor platform based on a specific application integrated circuit (application-specific integrated circuit part)

210‧‧‧Controller (processor)

212‧‧‧ memory

214‧‧‧Battery

216‧‧‧sensor interface

218‧‧‧ sensor interface

220a, 220b‧‧‧ electrodes

222‧‧‧Accelerometer

224‧‧‧temperature sensor

226‧‧32 kHz crystal (32 kHz clock)

228‧‧‧Soft circuit

230‧‧‧ room temperature and body temperature (temperature) sensors

232‧‧‧GSR/Electrodermal Activation (EDA) Sensor

234‧‧‧Common Sequence Bus (USB)

236‧‧‧Light Emitting Diodes (LEDs)

238‧‧‧Test interface

240‧‧‧User button (button)

300‧‧‧Box function chart

310‧‧‧electrode input

316‧‧‧ sensor

318‧‧‧ Feedback Module

320‧‧‧Wearing conductive communication module

330‧‧‧Physical Sensing Module

340‧‧‧Complementary MOS temperature sensing module

350‧‧‧Three-axis accelerometer

360‧‧‧Processing Engine

370‧‧‧ Non-volatile memory

380‧‧‧Wireless communication module

420‧‧‧ Event Marking System

422‧‧‧Frame

424‧‧‧swallowable materials

425‧‧‧ skirt

426‧‧‧swallowable materials

427‧‧‧ skirt

428‧‧‧Control device

500‧‧‧Disposable components

502‧‧‧bonded substrate

504a, 504b‧‧‧ electrodes

506a, 506b‧‧‧ electrical contacts

508‧‧‧Mechanical snap connection mechanism

510a, 510b‧‧‧ protruding elements

600‧‧‧Reusable components

602‧‧‧ Shell

604a‧‧‧ recess

606‧‧‧ bottom

702a, 702b‧‧‧ electrical contacts

704a‧‧‧Input/Output Address

704b‧‧‧Personal Identification Number

800‧‧‧Reusable components

802a, 804b‧‧‧ (skin) electrode

900‧‧‧Disposable components

902‧‧‧(skin) adhesive overlay

904‧‧‧Central section

1000‧‧‧Reusable components

1001‧‧‧ Receiver

1002‧‧‧Disposable components

1004a, 1004b‧‧‧ electrodes

1006a, 1006b‧‧‧ electrode terminals

1008‧‧‧ Shell

1010a, 1010b‧‧‧ two-conductor cable

1012‧‧‧Connector

1020‧‧‧Manually pressable operation buttons

1030‧‧‧Status ID LED

1100‧‧‧bonded substrate

1102‧‧‧Main adhesive layer

1104‧‧‧Secondary bonding layer

1106‧‧‧Edge, periphery

1108‧‧‧ Coverage

1110‧‧‧Upper casing plate

1120‧‧‧Integrated circuit components

1130‧‧‧ Lower casing plate

1140‧‧‧Adhesive patch

1141,1142,1143‧‧‧ Conductive column

1150‧‧‧Upper casing

1151,1152,1153‧‧‧ Skin contact column

1154‧‧‧ Conductive water colloid layer

1155‧‧‧ Non-conductive hydrocolloid

1156‧‧‧ Pressure sensitive adhesive

1170‧‧‧Porous layer

1180‧‧‧Upper support layer

1200‧‧‧Reusable components

1202‧‧‧ bottom

1204a‧‧‧Input/Output Address

1204b‧‧‧Personal Identification Number

1210‧‧‧Smart mobile phone (camera phone)

1212‧‧ images

1300‧‧‧External patch configuration

1310, 1320‧‧‧ electrodes

1330‧‧‧Upper elastic outer support

1350‧‧‧ under elastic support

1360‧‧‧Integrated circuit/battery assembly

1370, 1375‧‧‧ lead components

1 shows an aspect of a wireless communication system including a wearable wireless device having a mobile chip set.

2 is a system diagram of a face of a wearable wireless device.

3 is a block diagram of the integrated circuit assembly of the electronic module of the reusable component of the re-wearable wireless device shown in FIGS. 1 and 2.

Figure 4 shows an aspect of the event tagging system.

Figure 5 shows a face of a disposable assembly comprising an adhesive substrate, electrodes (shown in phantom), electrical contacts, and a mechanical snap-fit connection.

6 is a perspective top view of one of the reusable components of the electronic module including the housing in a housing that is configured to match the mechanical snap-fit connection of the disposable assembly shown in FIG.

Figure 7 is a perspective bottom view of one of the reusable components.

Figure 8 shows one of the reusable components.

Figure 9 shows a face of the adhesive cover.

Figure 10 shows one aspect of a wearable wireless device that includes a reusable component and a disposable component.

Figure 11 shows a face of the bonded substrate to be secured to the body.

Figures 12A and 12B show one aspect of the process of capturing an image of an input/output (I/O) address and a personal identification number (PIN) at the bottom of the reusable component.

Figure 13 is a 3D diagram of an external signal receiver according to a face.

Figure 14 provides an exploded view of the signal receiver shown in Figure 10 in accordance with a face.

Figure 15 provides an exploded view of a viscous patch assembly in accordance with a signal receiver shown in Figures 13 and 14.

Figures 16A through 16E provide various views of a two-electrode external signal receiver in accordance with a face.

Before the various embodiments of the wireless wearable device, system, and method are described in detail, it should be noted that the various embodiments disclosed herein are not limited to the application or use of the structure and Details of the arrangement of the components. Rather, the disclosed embodiments can be positioned or combined with other embodiments, variations and modifications thereof, and can be practiced or carried out in various ways. Accordingly, the embodiments of the wireless wearable devices, systems, and methods disclosed herein are illustrative and are not intended to limit the scope or application. In addition, the words and phrases used herein have been chosen for the purposes of the embodiments and are not intended to In addition, it should be understood that any one or more of the disclosed embodiments, the words of the embodiments, and/or examples thereof may be combined with any one or more of the disclosed embodiments, the words of the embodiments, and/or Or a combination of examples thereof, but is not limited thereto.

In the following description, like reference numerals indicate the same or the In addition, in the following description, it should be understood that words such as front, back, inner, outer, upper, lower, etc. are for convenience. See the vocabulary and does not constitute a restrictive term. The terms used herein are not meant to be limiting as long as the devices described herein, or portions thereof, may be attached or used in other orientations. Various embodiments will be described in detail with reference to the drawings.

The present invention generally relates to various aspects of wireless wearable devices, systems, and methods for monitoring at least one physiological and/or physical parameter of a wearer associated with a wearable wireless device and for using the monitored parameters Communicate to the communication device. The communication device is configured to communicate the monitored parameters remotely through the network.

It will be understood that the terms "pharmaceutical treatment" or "dosage form" as used in the present invention include various forms of ingested, inhaled, injected, resorbable, or otherwise consumed, and/or carriers thereof. For example, pills, capsules, gel caps, placebos, packaging carriers or vehicles, Chinese herbal medicines, medicines (OTC), supplements, prescription medications, swallowable event markers (IEM), etc. Wait.

1 shows a side of wireless system 100 that includes a re-wearable wireless device 102 that includes a mobile chip set, such as a single- or multi-wafer cellular radio. In one aspect, the wearable wireless device 102 is removably attached to the living body 104, such as a human or other life form of the living being. In one aspect, the wearable wireless device 102 is configured to monitor at least one parameter. The at least one parameter to be monitored may include, for example, physiological and/or physical parameters associated with the living being. For example, the wearable wireless device 102 can be configured to monitor parameters such as skin impedance, electrocardiogram signals, conductive transmission Current signal, wearer's position, temperature, heart rate, perspiration rate, humidity, altitude/barometric pressure, global positioning system (GPS), proximity, bacterial content, glucose level, chemical labeling, blood oxygen concentration, etc. Physical parameters, but are not limited to this.

In one aspect, the mobile phone is configured to wirelessly communicate the monitored parameters to a backend, remote server, or remote node 106 in the communication network over the communication network. In one aspect, the communication network is a cellular network or a cellular communication network 108. The mobile chipset enables the wearable wireless device 102 to make or receive data over a radio link while moving around a wide geographic area. This is achieved by connecting the cellular communication network 108 provided by the mobile phone operator and allowing access to the public telephone network. The communication network communicates with other networks 110 or the Internet 112 to access the backend server 106. The amount of data transmitted by the wearable wireless device 102 can be, for example, about 10 kilobytes per day to about 100 to 150 kilobytes per day.

In one aspect, when the wearable wireless device 102 is activated, the mobile chipset is used to initiate wireless transmission of information associated with the monitored parameters. Information associated with the monitored parameters may include, for example, raw measurement data, processed data, and/or any combination thereof. Information can also include identification codes, patient identification information (eg, name, address, phone number, email, social network URL), dosing unit identification, swallowable event tag system identification, when the dose package is opened Time and date stamps, time and date stamps when the swallowable event marking system is swallowed and activated by the patient.

When the wearable wireless device 102 is activated, the wearable wireless device 102 communicates with the handset signal tower 114 and the base station (BS) 116 and can access the Internet 112 via the cellular communication network 108. Accordingly, information received by the wearable wireless device 102 from the host 104 can be communicated to the remote node 106 via the Internet 112 or other network 110. Processing system 120 at remote node 106 receives the information and stores it for processing by repository 118.

Still referring to FIG. 1, remote node 106 includes processing system 120 communicatively coupled to database 118. Information relating to identity and medication type and dosage, such as all subjects 104 of the patient, may be stored in database 118. The processing system 120 receives information from the wearable wireless device 102 and accesses information associated with the remote node 106 in the database 118 to provide information to the care provider via the wearable wireless device 102. The remote node 106 can communicate information including a photo of the identified patient, the type of medication available to the care provider, and a confirmation of the dosage and type of medication selected by the care provider and delivered to the patient. The wearable wireless device 102 can communicate with the remote node 106 using any mode and communication frequencies available in the field, such as wireless, G2, G3, G4, real time, periodically according to a predetermined time delay, and Store and forward at a later time.

The communication carrier between the wearable wireless device 102 and the remote node 106 includes one or more networks. In various aspects, the network includes a local area network (LAN) and a wide area network (WAN), including the Internet, wired channels, wireless channels, including telephones, computers, and cable. Communication devices for radio, optical or other electromagnetic channels and combinations thereof, including but not limited to other devices and/or communication devices capable of/associating with components of communication data. For example, communication environments include in-body communication, various devices, various communication modes such as wireless communication, wired communication, and the like.

The processing system 120 at the remote node 106 can include a server configured to provide a subject indication authority, for example, as needed. For example, the server can be configured to allow the home care giver to participate in the subject's treatment regimen, for example, by allowing the home care giver to monitor the alerts and trends generated by the server (eg, web interface) and provide back to the patient support. The server can also be configured to provide a response directly to the subject, for example, in the form of a subject alert, a subject reward, which is communicated to the subject via the communication device. The server can also interact with health care professionals, such as nurses and physicians, who can use data processing algorithms to get health measures and meet subjects, such as health index summaries, warnings, cross-patient benchmarks, and provide clinical notifications. Communicate and return to support the patient. The server can also interact with pharmacies, nutrition centers and drug manufacturers.

In one aspect, the remote node 106 can store in the database 118 the time and date of the dosage form taken by the subject 104. Moreover, when the event tagging system is provided in the dosage unit, the time and date stamp when the event tagging system is swallowed by the patient can also be stored in the database 118. In addition, identification numbers such as serial numbers, for example, identification single or multi-dose packaging, individual patient identification type of packaging (single, multiple, morning, afternoon, evening, daily, weekly, monthly dosing events, etc.), pre- package The date, source, and contents of the package can be stored, for example, in database 118. In some aspects, one or all of the expiration date or shelf life of the drug or dosage form may also be stored in database 118.

The mobile chipset in the wearable wireless device 102 provides bidirectional data communication between the wearable wireless device 102 and the cellular communication network 108 via the handset signal tower 114. In one aspect, when the subject 104 swallows a dosage form that includes an event indicator system, the event indicator system communicates with the wearable wireless device 102, which includes various electronic modules for The event indicator system receives a unique signature and communicates with the cellular communication network 108. It should be understood in various aspects that the wearable wireless device 102 can be configured to communicate with access points and other mobile devices. Thus, the wearable wireless device 102 can effectively communicate with the remote node 106 over the Internet 112 via a local area network (LAN) or cellular communication network 114.

In other aspects, the wearable wireless device 102 can be triggered to initiate data transmission to the cellular communication network 108 based on various triggers. These triggers include timers, instant clocks, events, swallowing of detected event tagging systems, detection of specific codes received from event tagging systems, receipt of specific monitoring parameters or values of such monitoring parameters, from cellular The communication network 108 receives trigger data and the like, but is not limited thereto.

2 is a system diagram of a face of the wearable wireless device 102. In one aspect, the wearable wireless device 100 is a two-piece device that includes a disposable component 202 and a reusable component 204. The reusable component 204 includes an electronic module. The electronic module of the reusable component 204 includes Wireless communication circuitry 206, such as a mobile chipset RF wireless circuitry, or a simple cellular radio. The electronic module of the reusable component 204 includes an ASIC-based sensor platform 208 that includes various hardware and software frameworks that implement the wearable wireless device 102. In one aspect, an ASIC-based sensor platform 208 can be placed on and interact with a printed circuit board assembly (PCBA). Wireless communication circuitry 206 can be a low power mobile chipset and configured to connect to cellular network 108 and other wireless devices (mobile phones, smart phones, tablets, notebooks, gateway devices, etc.). The disposable component 202 interacts with the printed circuit board assembly and the first electronic module 204. In one aspect, the electronic module 204 and the disposable component 202 can each include additional modules that are or are not on the printed circuit board assembly, or in other orientations, which can be placed on the printed circuit board. On the assembly.

In one aspect, the reusable electronics module 204 provides a sensor platform and includes circuitry designed to interact with different sensors, and includes various combinations of the following components. In various aspects, the ASIC-based sensor platform of the reusable electronic module 204 includes an "ASIC-based sensor platform based on an application-specific" circuit 208 Single low-power application-specific integrated circuit (ASIC)/wafer provides analog front end, vector/digital signal processing, microprocessor and memory combination, "ASIC-based sensor based on specific applications" Platform "208 has multiple functions: for detecting swallowable event markers The software defines the sensors for radio, electrocardiogram, sensing and decoding of AC skin impedance measurements, temperature measurements, DC skin impedance (eg, GSR) measurements, and other bio/medical data.

In one aspect, the reusable electronic module 204 includes an application specific integrated circuit (ASIC) sensor platform 208, a controller or processor 210, such as a microcontroller unit (MCU), radio frequency (RF) wireless communication. Circuit 206 and other components described below.

In a facing, reusable electronic module application specific integrated circuit 204 (ASIC) portion 208 may include a core processor 210, such as, for example, for the instant application ARM Cortex ^TM M3 processor, such as e.g. Vector operation accelerator signal processing accelerator, program memory, data memory, such as serial interface of serial peripheral interface (SPI), universal asynchronous transceiver (UART), two-wire multi-master serial single-ended bus interface (I2C), general purpose input/output (GPIO), instant clock, analog-to-digital converter (ADC), biopotential signal gain and regulation circuitry, LED driver, and more. The reusable electronic module 204 also includes a connection port to the external memory, a connection port to the external sensor, and a hardware accelerator. The processor 210 receives signals from the various sensors by operating an analog comparator of the analog front end and by receiving digital data from the sensor in an ADC digitizer. Processor 210 then processes the data and stores the results in memory 212 in the form of data records. In one aspect, processor 210 can have a very long instruction (VLIW) processor architecture.

In one aspect, the reusable electronic module 204 also includes A serial bus (USB) 234, an accelerometer 222, a memory 212, one or more light emitting diodes (LED) 236, a test interface (I/F) 238, a 32 kHz crystal 226, can be used A user button 240, a sensor interface 216, 218, and a battery 214 (eg, a button cell, a disposable battery) that are in communication with an external device. In one aspect, battery 214 can be a rechargeable battery rather than a disposable battery. In other aspects, the reusable electronics module 204 can include a gyroscope, and circuitry for processing electrocardiogram (ECG), temperature, and accelerometer signals. In other aspects, the reusable electronic module 204 can also include a body component and a blood oxygen pulse oximetry circuit that monitors functional arterial blood by calculating the ratio of oxygenated hemoglobin to heme that can deliver oxygen. Oxygen saturation. The oximetry pulse oximetry circuit can be configured to provide continuous, non-invasive oximetry, as well as a plethysmographic waveform in one aspect. The heart rate value can be derived from the pulse oximetry signal.

In one aspect, the reusable electronic module 204 includes a radio frequency wireless communication circuit 206. The radio frequency wireless communication circuit 206 includes an antenna for receiving and transmitting a wireless signal, a transmitter circuit, a receiver circuit, and a link master controller including a connection (establishing a link) to another external wireless device and transmitting data. The organization, as described in more detail below. In one aspect, the link master establishes a connection to an external device. As the body of the link, the link master performs control of data transmission through a link to an external device, including timing control and radio frequency control (frequency hopping). The link master sends a signal with an instruction to the external device, which gives the number of data records stored in the memory (all data records) The total number and the total number of records for each data type). In various aspects, the RF wireless communication circuit 206 can use a set of mobile chips available from a variety of vendors including, but not limited to, Tegra of Nvidia, Snapdragon of Qualcomm, OMAP of Texas Instruments, Exynos of Samsung, Ax of Apple, ST-Ericsson's NovaThor, Intel's Atom, Freescale Semiconductor's i.MX, Rockchip's RK3xxx, AllWinner's A31, etc. are implemented. These mobile chipsets are used by mobile phones, also known in the art as "actions", "wireless", "cellular radiotelephones", "mobile phones", "handheld phones (HP)", "smart phones", etc. .

After each connection, processor 210 continues to receive all of the sensor signals, processes the data, and stores the new data records in memory 212. Each subsequent connection link main controller transmits a signal having a new data record to the external device due to the last connection, and confirms that the record was successfully transmitted. The link master controller receives, from the external device, a signal established if the external device is ready to receive the data record, and also receives an established signal from the external device that the data record was not successfully transmitted. The link master controller avoids repeating the transfer of the data record that has been transferred, while increasing the power usage of the battery 214 for longer operation and resending all data records that were not successfully transmitted. The link master can delete all or part of the successfully transmitted data record from the memory at a later time (eg, when memory 212 is full).

In one aspect, the reusable electronic module 204 is included in the electrodes 220a, 220b (E1, E2) and one or more bandpass filters or passes Sensor interfaces 216, 218 between the tracks. The sensor interfaces 216, 218 provide an analog front end and may include a programmable gain or fixed gain amplifier, a programmable low pass filter, and a programmable high pass filter. The sensor interfaces 216, 218 can include active signal conditioning circuitry including, for example, strain gauge measurement circuitry. One channel receives low frequency information associated with physiological data of the subject (eg, the user) and the other channel receives high frequency information associated with the electronic device in the subject. In an alternate aspect, additional channels may be provided to receive DC data of the subject. The high frequency information is passed through a digital signal processor (DSP) implemented in the ASIC portion 208 and then to the processor 210 (e.g., control processor) portion of the wearable wireless device 102 for decompression and decoding. The low frequency information is passed through the DSP portion of the ASIC portion 208 and then to the processor 210, or directly to the processor 210. The DC information is passed directly to the processor 210. The DSP portion of the ASIC portion 208 and the processor 210 decode high frequency, low frequency, and DC information or data. This information is then processed and ready to be transmitted.

In one aspect, signal processing may or may not be applied to raw data collection. Signal processing can occur in real space, complex space, or in polar coordinate space. Functions include filters such as finite impulse response (FIR) and infinite impulse response (IIR), mixers, fast Fourier transforms (FFTs), coordinate scalers, and others. Raw data can simply be stored and processed downstream. The signal processing may occur in a processor (e.g., ARM Cortex ^TM M3), or may occur in the signal processing accelerator 208 is incorporated in the ASIC portion.

In one aspect, the reusable electronic module 204 includes acceleration Meter 222 and one or more temperature sensors 224. In one aspect, two temperature sensors are provided, the two temperature sensors are the same but placed in different positions, one close to the skin and the other close to the circumference for measuring additional data. Temperature sensor 224 can be configured to measure and record skin, surroundings, and board temperature. Temperature sensor 224 can be used to measure the heat flux between the skin and the surrounding temperature sensor. In one aspect, single or multiple temperature sensors 224 are thermal resistors having a negative temperature coefficient (NTC) or positive temperature coefficient (PTC), and in the other orientation, single or multiple temperature sensors 224 An integrated semiconductor device is used. This information is provided to the processor 210 and can be processed by the processor 210 and prepared for transmission by the transmitting portion of the radio frequency wireless communication circuit 206. The measured physiological information is processed by the processor 210 and can be sent as immediate or raw data, or a derived amount or parameter can be sent.

In one aspect, the accelerometer 222 can be a three-axis accelerometer with a resampling frequency correction processor. Digital accelerometer 222 sensors typically include MEMS based acceleration sensor elements, digitizers, and digital interface control logic. These accelerometers typically use a low-accuracy resistor-capacitor (RC) oscillator to gate the digitizer sample input. In order to use signals from such an accelerometer 222 in a signal processing algorithm, the accuracy of the RC oscillator is insufficient. Thus, in one aspect, the reusable electronics module 204 includes an accelerometer sampling frequency correction processor that takes signals from the accelerometer 222 and performs resampling to compensate for errors in the RC oscillator.

In one aspect, the accelerometer 222 sampling frequency correction processor includes a reference clock (high accuracy oscillator), fixed upsampling An up-sample section, a digital filter, a programmable down-sample section, and a control circuit that selects a down-sampling coefficient based on timing of comparing signals from the accelerometer and reference. The resampling function maintains an alignment reference clock in the sliding window to produce an accurate sampling rate. The algorithm calibrates the real-time 32 kHz clock (X-TAL) 226. The accelerometer 222 sampling frequency correction processor sets a downsampling factor for each data frame from the accelerometer signal. The method provides for continuously tracking the timing of the accelerometer signals and selecting down-sampling coefficients to minimize accumulated timing errors. This allows the continuous accelerometer 222 digital data to be aligned with an accurate clock with high precision.

In one aspect, the reusable electronic module 204 uses a low power, low memory data storage and transfer scheme. In one aspect, the storage and transfer of data in the memory 212 of the wearable wireless device 102 is optimized for low power and low memory usage. The sensor data is stored as a record having a type identifier in the memory 212, respectively. The record in the packet payload is transferred to the external device by the radio frequency wireless communication circuit 206 in the same format as stored on the wireless wearable sensor 100. The records are sequentially stored in various lengths to optimize space usage. The data directory is covered to allow fast record read access from memory 212. The data catalog is covered to allow fast calculation of data records by type.

In one aspect, the reusable electronic module 204 uses a data storage and transfer scheme with high guaranteed integrity. The memory storage and transfer scheme of the wearable wireless device 102 is designed for high guaranteed data integrity. For each memory stored in the wearable wireless device 102 The data record in 212 has an error detection code that can be used to detect the deterioration of the data record. When the re-worn wireless device 102 reads a data record from the memory 212 before the data packet is transferred to the external device, the error detection code is checked. When the re-worn wireless device 102 detects a deterioration in the stored data record, the error signal is transmitted by the radio frequency wireless communication circuit 206 to the external device. Each packet that is transferred from the wearable wireless device 102 to the external device includes an error detection code that can be used by the external device to detect packet degradation.

In one aspect, the signal processing accelerator portion of ASIC portion 208 includes a computational engine that is optimized to perform highly efficient signal processing tasks. In an embodiment, the signal processing function is hard coded into the logic. Such an embodiment may be 10 times or more efficient than a software-based algorithm executed in software running on processor 210 or a microcontroller unit. Efficiency can be in wafer size, power consumption, or clock speed or a combination of all three. Other embodiments maintain some level of stylization, but employ an execution unit that is optimized for computing power. An example is the fast Fourier transform butterfly engine (FFT-butterfly engine). For various sized data sets, this engine can use Fast Fourier Transform calculations, but maintains significant efficiency gains compared to software running on processor 210. The execution unit may also be a multiply-accumulate unit (MAC), which is a shared DSP functional section, or may be a floating-point arithmetic unit or an FIR filter primitive or the like. In these cases, the efficiency of processing for a given integrated circuit is better than the efficiency of the software on processor 210, but less than the efficiency of dedicated hardware, yet it is more flexible.

The signal processing accelerator maintains a mediation between the processors 210 surface. The interface may include first-in-first-out (FIFO) registers, dual port memories, and direct memory access (DRAM) of the processor 210. )engine), and/or scratchpad. The interface typically includes some form of contention recognition or avoidance that can be processed at the scratchpad level or at the memory segment level. The involved mechanisms may include a register of flag registers that may be polled by the processor 210 and the signal processing accelerator, interrupting the signal of the blocking or delay function, which retains the read or write request until the higher priority device Has completed its activities.

In one aspect, the disposable component 202 is coupled to the reusable electronic module 204 on the PCBA with an attachment to interact with the monitored item (human, animal, machine, building, etc.) One or more sensors. In one aspect, the disposable component 202 can include a flexible circuit 228, a battery holder or housing (lid), and one or more sensors including, but not limited to, room temperature and body temperature (temperature) sense Detector 230 (live or inactive), electrocardiogram sensor, GSR/electric dermal activation (EDA) sensor 232, body composition (50 Hz) sensor, oximetry/pulse oximetry sensor, Strain gauge sensors and more. The various algorithms executed by ASIC portion 208 or processor 210 provide heat flux, heart rate (HR), heart rate (HRV), respiration, pressure, electrocardiogram, pace, body angle, fall detection, and the like.

In one aspect, the flexible circuit 228 includes an interface component that electrically interacts with electronic circuitry on the PCBA. The soft circuit 228 provides a platform for groupable attitudes and enables multiple sensor configurations to be combined with a single The body's PCBA interacts and can electrically interact with the reusable electronic module 204. In one aspect, the electrodes 220a, 220b of the stainless steel dome of the GSR/EDA sensor 232 are electrically coupled to the PCBA via the flexible circuit 228.

The wearable wireless device 102 collects data from the various sensors, applies a signal processing algorithm to the collected data, stores the resulting information in memory, and forwards the data/information to another device using a wireless or wired connection. The user interface includes one or two light emitting diodes 214 and buttons 234.

Power is supplied from the disposable battery 214, but may also be provided from a secondary battery. The battery 214 of the electronic module of the reusable component 204 can select the peak current of the source, which is sufficient to support the peak current of the cellular radio with a rechargeable lithium ion or lithium polymer battery (lithium polymer or lithium square battery). The type, but other types of primary and secondary batteries can be considered. In some aspects, the disposable component can include a battery if a primary battery is used. In some aspects, the reusable component can include an electronic component and battery 214, assuming that the secondary battery is used. The wearable wireless device 102 can include a recharger to recharge the reusable module. The body 104 can be supplied with a plurality of reusable components to ensure continuity of use when the reusable components are being charged. The device size can be in the range of 25 cubic centimeters for the current embodiment, with the form factor that the wearable wireless device 102 becomes smaller due to advances in semiconductor devices and battery technology. Half of the battery size can be limited by the peak current consumption of the mobile chipset, not the capacity. In most cases, the current consumption of the mobile chipset will be limited by the deactivation. / Turn off the wafer and periodically and several times a day power the chip and transfer data.

One of the challenges in placing a cellular radio into the wearable wireless device 102 is the power source, battery 214. The cellular radio cellular communication device 206 will consume a peak current of from about 700 to about 800 milliamps, which may be a challenge for implementation with the battery 214. A rechargeable battery 214, such as a lithium polymer or lithium square battery, acts as an energy source to provide sufficient current at peak load. Another key feature is that the wearable wireless device 102 lasts for at least a week or two, while a typical mobile phone battery lasts only one or two days or days. To extend the battery life of the wearable wireless device 102 from about one week to about three weeks, the connection to the Internet 112 (FIG. 1) can be limited to several times a day. The wearable wireless device 102 can store data in the memory 212 and buffer the data thereon. Therefore, it is possible to connect to the Internet 112 several times a day, or even up to ten times a day. Between the connections of the Internet, the wearable wireless device 102 can turn off the wireless communication device 206. In one aspect, the wearable wireless device 102 can be placed in a deep sleep state or a sleep state that consumes only a few microamps of current, rather than a few hundred microamperes or milliamps when it is idle. Current.

In order to smooth out a peak of 800 milliamps from a reference current draw of 100 to 200 milliamps, a capacitor can be used across battery 214. A capacitor large enough to effectively reduce the peak load seen from the battery 214. The capacitor can be, for example, a super capacitor. For example, with this technology, a 300 mAh battery per hour might be enough to supply 800 mAh. Pei.

The wearable wireless device 102 can exit the sleep state on a timing basis or on an event basis. In one aspect, the wearable wireless device 102 has its own low power microcontroller that operates on a continuous basis. The event marker detection algorithm, electrocardiogram sensing, heart rate sensing, and other physiological sensing functions operate continuously, and when the timer expires, it wakes up the wireless communication circuit 206 to connect to the cellular network 108 (figure 1) and the Internet 112 (Figure 1). In another aspect, the wireless communication circuit 206 can exit the sleep state based on an event such as, for example, activity data measured by the accelerometer 222. Events or activities, such as arrhythmia detection, will require immediate load reduction. The event may include the body 104 (FIG. 1) pressing the user button 234. In certain circumstances, events may be inactive. Alternatively, it may be that the body 104 has fallen or the data has shown an unusual pace through the accelerometer 222. In one aspect, the wearable wireless device 102 can include a microphone device. Accordingly, the wireless communication circuit 206 can be activated based on a wheezing event caused by asthma or shortness of breath. The lack of medication can also trigger the wireless communication circuit 206 to exit the sleep mode.

The mobile chipset can also be used as a telephone for voice communication by enabling/powering it with a user interface (UI) provided on the wearable wireless device 102, and using voice recognition to make it dial. The user interface can include a button 234, an accelerometer 222 with graphics recognition capabilities, a speaker, and a microphone.

The disposable component 202 can include electrodes 220a, 220b and The type of one or more adhesives used to bond the wearable wireless device 102 to the skin of the body 104 (Fig. 1) has a general life span of from about 3 days to about 10 days for most people. The sensor data may include electrocardiogram data (via hydrocolloid electrodes 220a, 220b), accelerometer data up to three axes, temperature data, adjacent skin (thermal resistance), environment (or housing temperature away from the body) ( Thermistor), the temperature on the PCBA (the device incorporated into the ASIC unit 208), the GSR, the EDA (discrete stainless steel electrode), the high frequency, the in vivo electrical signal -10 kHz or higher, and the transmission through the hydrocolloid skin The electrodes (same as the ECG) were sampled.

As shown, the wearable wireless device 102 can include a memory 212. In various aspects, memory 212 can include any machine readable or computer readable medium capable of storing data, including both volatile and non-volatile memory. For example, the memory may include read only memory (ROM), random access memory (RAM), dynamic random access memory (DRAM), double data rate dynamic random access memory (DDR-DRAM). Synchronous Dynamic Random Access Memory (SDRAM), Static Random Access Memory (SRAM), Programmable Read Only Memory (PROM), Erasable Programmable Read Only Memory (EPROM), Electronically Erasable Program-read only memory (EEPROM), flash memory (eg, NOR or NAND flash memory), associated memory (CAM), polymer memory (eg, ferroelectric polymer memory), phase change memory Body (for example, two-way memory), ferroelectric memory, 矽-oxide-nitride-oxide-矽 (SONOS) memory, disk memory (for example, disk, hard disk, CD, disk) , or card (for example, magnetic card, optical card) Or any other type of medium suitable for storing information.

The wearable wireless device 102 can include a processor 210, such as a central processing unit (CPU). In various aspects, the processor 210 can be implemented as a general purpose processor, a single chip multiprocessor (CMP), a dedicated processor, an embedded processor, a digital signal processor (DSP), a network processor, a media processor. , input/output processors, media access control (MAC) processors, radio baseband processors, coprocessors, such as Complex Instruction Set Computer (CISC) microprocessors, Reduced Instruction Set Computing (RISC) microprocessors, And/or a microprocessor of a very long instruction (VLIW) microprocessor, or other processing device. The processor can also be implemented by a controller, a microcontroller, an application specific integrated circuit (ASIC), a field programmable gate array (FPGA), a programmable logic device (PLD), and the like.

In various aspects, the processor 210 can be arranged to run an operating system (OS) and various mobile applications. Examples of operating systems include, for example, an operating system generally known as the Microsoft Windows OS, and any other proprietary or open operating system. Examples of mobile applications include, for example, phone applications, camera (eg, digital cameras, cameras) applications, browser applications, multimedia player applications, game applications, messaging applications (eg, e-mail, SMS, multimedia), viewer app, and more.

In various aspects, processor 210 can be arranged to receive information via a communication interface. The communication interface can include any suitable hardware, software, or combination of hardware and software capable of coupling the wearable wireless device 102 to one or more networks and/or devices.

The wireless communication mode includes any mode of communication between points that uses, at least in part, wireless technology including various protocols and combinations of protocols associated with wireless transmissions, data, and devices. Points include, for example, wireless devices such as wireless headsets, audio and multimedia devices and devices such as audio players and multimedia players, phones including mobile phones and wireless phones, and computer and computer related devices and components, such as Printer.

The wired communication mode includes any mode of communication between points that utilizes wired technologies including various protocols and combinations of protocols associated with wired transmissions, data, and devices. Points include, for example, devices such as audio and multimedia devices and devices, such as audio players and multimedia players, phones including mobile phones and wireless phones, and computer and computer related devices and components such as printers.

In various aspects, the communication interface may include one or more interfaces, such as, for example, a wireless communication interface, a wired communication interface, a network interface, a transmission interface, a receiving interface, a media interface, a system interface, a component interface, a switching interface, and a chip. Interface, controller, etc. For example, when implemented by a wireless device or in a wireless system, the local node 106 can include a wireless interface with one or more antennas, transmitters, receivers, transceivers, amplifiers, filters, control logic, and the like. Wait.

In various aspects, the wearable wireless device 102 can provide voice and/or data communication functionality in accordance with different types of cellular radiotelephone systems. In various embodiments, the described aspects can communicate over a wireless sharing medium in accordance with a number of wireless communication protocols. Examples of wireless communication protocols may include various wireless local area network (WLAN) communication protocols, Including the Institute of Electrical and Electronics Engineers (IEEE) 802.xx series of agreements, such as IEEE 802.11a / b / g / n, IEEE 802.16, IEEE 802.20 and so on. Other examples of wireless communication protocols may include various wireless wide area network (WWAN) communication protocols, such as GSM cellular radiotelephone system protocols with GPRS, CDMA cellular radiotelephone system protocols with 1xRTT, EDGE systems, EV-DO systems, EV-DV system, HSDPA system, etc. Further examples of wireless communication protocols may include wireless personal area network (PAN) communication protocols, such as infrared protocols, from Bluetooth specification versions including enhanced data rates v1.0, v1.1, v1.2, v2. 0, v2.0 and one or more Bluetooth configuration of the Special Interest Group (SIG) series of agreements and so on. Still another example of a wireless communication protocol includes near-field communication techniques and protocols, such as electromagnetic induction (EMI) technology. Examples of EMI technologies may include passive or active radio frequency identification (RFID) protocols and devices. Other suitable protocols may include ultra-wideband (UWB), digital office (DO), digital homes, trusted platform modules (TPMs), wireless transmission modules, and the like.

In various embodiments, the described aspects may include portions of a cellular communication system. Examples of cellular communication systems may include CDMA cellular radiotelephone systems, GSM cellular radiotelephone systems, North American digital handset (NADC) cellular radiotelephone systems, time-division multiple access (TDMA) cellular radiotelephone systems, extended TDMA (E-TDMA) Honeycomb Wireless Telephone System, Narrowband Advanced Mobile Phone Service (NAMPS) Honeycomb wireless telephone system, third generation (3G) wireless standard system conforming to the third generation partnership project (3GPP), such as WCDMA, CDMA-2000, UMTS cellular radiotelephone system, fourth generation (4G) Wireless standard systems and more.

Moreover, in various aspects, the wearable wireless device 102 can be combined and/or associated with, for example, communication, various devices. Such devices can generate, receive, and/or communicate data, such as physiological data. Devices include, for example, "smart" devices such as, for example, electronic slot machines, handheld video games, gaming devices associated with gaming and entertainment activities.

In addition to the standard voice features of the phone, the various aspects of the mobile phone can support many additional services and accessories, such as text messaging (SMS), email, packet exchange for accessing the Internet, java games, For example, wireless transmission of short-range data/voice communication, infrared, cameras with video recorders, and multimedia messaging systems (MMS) for transmitting and receiving photos and movies. Some of the mobile phones are oriented to a cellular network connected to a base station (base station), which is then interconnected to the public switched telephone network (PSTN) or interconnected to satellite communications in the case of satellite phones. The various aspects of the mobile phone can be connected to the Internet, at least in part, which can be navigated using a mobile phone.

Certain embodiments may be implemented, for example, using a machine-readable medium or object that can store instructions or groups of instructions that, if executed by a machine, may cause the machine to perform the methods and/or operations in accordance with the embodiments. Such machines may include, for example, any suitable processing platform, meter Computing platforms, computing devices, processing devices, computing systems, processing systems, computers, processors, and the like, and can be implemented using any suitable combination of hardware and/or software. A machine-readable medium or object may include, for example, any suitable type of memory unit, memory device, memory object, memory medium, storage device, storage item, storage medium, and/or storage unit, eg, memory, Removable or non-removable media, erasable or non-erasable media, overwritable or rewritable media, digital or analog media, hard disk, magnetic disk, CD-ROM (CD- ROM), recordable compact disc (CD-R), rewritable compact disc (CD-RW), compact disc, magnetic media, magneto-optical media, removable memory card or disc, various types of digital compact disc (DVD), magnetic tape , card, and so on. Instructions may include any suitable type of encoding, such as source encoding, compiled code, interpreted encoding, executable encoding, static encoding, dynamic encoding, and the like. Instructions can be executed using any suitable high-level, low-order, object-oriented, visual, compiled, and/or interpreted programming language, such as C, C++, Java, BASIC, Perl, Matlab, Pascal, Visual BASIC, and combination. Language, machine coding, etc.

In various aspects, the wearable wireless device 102 also communicates, for example, receiving and transmitting, non-physiological data. Examples of non-physiological data include, for example, game rules and data generated by an independent cardiac related device such as an implantable heart rate regulator and passed directly or indirectly to a hub.

Re-wearable wireless device 102 can include generally other mobile devices, such as, for example, personal communication devices, handheld devices, and Additional features found in the phone. In various aspects, the wearable wireless device 102 can be included in a handheld portable device, a computer, a mobile phone (sometimes referred to as a smart phone), a tablet personal computer (PC), a life information station, a desktop computer, or A function found in a notebook computer, or any combination thereof. Examples of smart phones include, for example, the following products known as Blackberry, iPhone, Android, Windows Phone, and the like. Although some of the wearable wireless device 102 may be described by way of example for use with a mobile or fixed computing device implemented as a smart phone, personal digital assistant, laptop, desktop computer, it should be Understanding the various aspects is not limited to this content. For example, a mobile computing device can include, or can be implemented as, any type of wireless device, mobile station, or such as a notebook, ultra-thin notebook, personal digital assistant (PDA), mobile phone, mobile Phone/PDA combination, mobile unit, subscriber station, user terminal, portable computer, handheld computer, palmtop computer, wearable computer, media player, pager, message device, data communication device, etc. A portable computing device for a power source (eg, a battery). Stationary computing devices, for example, can be implemented as desktop computers, workstations, client/server computers, and the like.

3 is a block diagram 300 of the integrated circuit assembly of the electronic module of the reusable component 204 of the re-worn wireless device 102 of FIGS. 1 and 2. In FIG. 3, the integrated circuit component of the electronic module of the reusable component 204 of the wearable wireless device 102 includes an electrode input 310. Electrically coupled to the electrode input 310 is a transbody conductive communication module 320 and physiological sensing module 330. In one aspect, the body-worn conductive communication module 320 is implemented, for example, as a first high frequency (HF) signal chain, and the physiological sensing module 330 is implemented, for example, as a second low frequency (LF) signal chain. Also shown are a complementary metal oxide semiconductor (CMOS) temperature sensing module 340 (for detecting ambient temperature) and a three-axis accelerometer 350. The wearable wireless device 102 also includes a processing engine 360 (eg, a microcontroller and a digital signal processor), a non-volatile memory 370 (for data storage), and a mobile chipset for receiving from a cellular communication network. And/or a wireless communication module 380 that transmits data. In various aspects, the communication modules 320, 380 can include one or more transmitter/receiver (transceiver) modules. As used herein, the term "transceiver" can be used in a very general sense to include a transmitter, a receiver, or a combination of both, but is not limited thereto. In one aspect, the body-worn conductive communication module 320 is configured to communicate with the event tagging system 420 (FIG. 4).

The sensor 316 generally contacts the body 104 (Fig. 1), for example, removably attached to the body. In various aspects, the sensor 316 can be removably or permanently attached to the wearable wireless device 102. For example, the sensor 316 can be removably coupled to the wearable wireless device 102 by a snapping metal stud. Sensor 316 can include, for example, various devices capable of sensing or receiving physiological data. Types of sensors 316 include, for example, electrodes such as biocompatible electrodes. The sensor 316 can be configured, for example, as a pressure sensor, motion sensor, accelerometer, electromyography (EMG) sensor, event marker system, biopotential sensor, electrocardiogram sensor, temperature Sensing , tactile event marker sensor, and impedance sensor.

The feedback module 318 can be implemented in software, hardware, circuitry, various devices, and combinations thereof. The functionality of feedback module 318 provides for communication with body 104 (FIG. 1) in a prudent, alert, and careful manner as described above. In various aspects, feedback module 318 can be implemented to communicate with body 104 using techniques that employ visual, audible, vibrating/tactile, olfactory, and gustatory techniques.

FIG. 4 shows an orientation of the event tagging system 420. In various aspects, the event tagging system 420 can be used in association with any of the drug products as described above to confirm that at least one of the correct dosage of the drug and the correct type is delivered to the patient, and in some aspects, when The patient is judged when taking the drug product. However, the scope of the invention is not limited by the environments and pharmaceutical products that can be used with system 420. For example, system 420 can be activated in a wireless mode, in a current mode by placing system 420 in a capsule and then placing the capsule in a conductive fluid, or in a combination thereof, or exposing system 420 to the air. . Once placed in the electrically conductive fluid, for example, the capsule will dissolve over a period of time and release the system 420 into the electrically conductive fluid. Thus, in one aspect, the capsule will contain system 420 and no product. Such capsules can then be used in any environment when a conductive fluid is present and is accompanied by any product. For example, the capsule can be dripped into a container filled with jet fuel, saline, ketchup, motor oil or any similar product. Additionally, to record the occurrence of an event, the capsule containing system 420 can be swallowed while any pharmaceutical product is swallowed, as when taking the product.

In a particular example of system 420 incorporating a drug or pharmaceutical product, system 420 is activated to a current mode when the product or pill is swallowed or exposed to the air. System 420 controls the conductivity to produce a unique current signature that is detected by, for example, the wearable wireless device 102 to indicate that the medical product has been taken. When activated in the wireless mode, the system controls the modulation of the capacitive plates to produce unique voltage signatures associated with the detected system 420.

In one aspect, system 420 includes a frame 422. Frame 422 is the base for system 420 and a plurality of components are attached to, deposited on, or secured to frame 422. In this aspect of system 420, swallowable material 424 is physically associated with frame 422. Material 424 can be chemically deposited, evaporated, fixed, or built into the frame, which may be referred to herein as "deposition" relative to frame 422. Material 424 is deposited on one side of the frame 422. Related materials that can be used as material 424 include, but are not limited to, copper, copper chloride or copper iodide. Material 424 is deposited by agreement of physical vapor deposition, electrodeposition, plasma deposition, and the like. Material 424 can be from about 0.05 to about 500 [mu]m thick, such as from about 5 to about 100 [mu]m thick. The shape is controlled by shadow mask deposition or photolithography and etching. Moreover, even if only one region is shown for depositing material, as desired, each system 420 can include two or more electrically distinct regions on which material 424 can be deposited.

On the different sides, which are opposite sides as shown in Figure 7, another swallowable material 426 is deposited such that the materials 424, 426 are different and isolated from each other. Although not shown, the different sides selected may be material 424 The side below the selected side. The scope of the invention is not limited by the selected side, and the word "different side" may mean any of a plurality of sides different from the first selected side. In various orientations, different materials can be positioned on the same side at different locations. Moreover, although the shape of the system is shown as a square, the shape can be any geometrically suitable shape. Materials 424, 426 are selected such that when system 420 is in contact with a conductive liquid, such as body fluid, they create a voltage potential difference. Related materials for material 426 include, but are not limited to, magnesium, zinc or other negatively charged metals. As indicated above with respect to material 424, material 426 can be chemically deposited, evaporated, fixed, or built onto the frame. Likewise, an adhesive layer may be necessary to aid in the bonding of material 426 (and material 424 when needed) to frame 422. The adhesive layer typically used for material 426 is Ti, TiW, Cr, or the like. The anode material and the adhesion layer can be deposited by physical vapor deposition, electrodeposition or plasma deposition. Material 426 can be from about 0.05 to about 500 [mu]m thick, such as from about 5 to about 100 [mu]m thick. However, the scope of the invention is not limited by the thickness of any material or the type of process used to deposit or fix the material to the frame 422.

In accordance with the proposed disclosure, materials 424, 426 can be any pair of materials having different electrochemical potentials. Moreover, in embodiments where system 420 is used in a living organism, materials 424, 426 can be vitamins that can be absorbed. More specifically, materials 424, 426 can be fabricated in any of two materials suitable for the environment in which system 420 will operate. For example, when used with a swallowable product, materials 424, 426 are any material that can be swallowed with different electrochemical potentials. Correct. Illustrative examples include examples of system 420 in contact with an ionic solvent, such as gastric acid. Suitable materials are not limited to metals, and in particular embodiments, the pair of materials are selected from metals and non-metals, for example, from metals such as magnesium and salts such as copper chloride or copper iodide. ) a pair made. Regarding the active electrode material, any pair of materials - metals, salts or intercalation compounds - having suitable and different electrochemical potentials (voltages) and low interfacial resistance are suitable.

Materials and related pairs include, but are not limited to, those reported in Table 1 below. In an embodiment, one or both of the metals may be non-metal doped, for example, to enhance the voltage potential generated between the materials when they are in contact with the conductive liquid. Non-metals can be used as doping media in certain embodiments including, but not limited to, sulfur, iodine, and the like. In other embodiments, the material is copper iodide (CuI) as the anode and magnesium (Mg) as the cathode. The invention is directed to the use of electrode materials that are harmless to the human body.

Thus, when system 420 is in contact with the electrically conductive liquid, a current path is formed via the electrically conductive liquid between the different materials 424, 426. Control device 428 is secured to frame 422 and is electrically coupled to materials 424, 426. Control device 428 includes electronic circuitry, such as control logic capable of controlling and changing the conductivity between materials 424, 426.

A voltage potential established between the different materials 424, 426 provides a power source for operating the system and generating a current through the conductive liquid and system 420. In one aspect, system 420 operates in a DC mode. In an alternative aspect, system 420 controls the direction of the current such that the direction of the current is reversed in a cyclic manner, similar to alternating current. When the system reaches a conductive fluid or electrolyte (wherein the fluid or electrolyte component is from a physiological fluid, such as the stomach When the acid is provided, the current path between the different materials 424, 426 is completed outside of the system 420; the current path through the system 420 is controlled by the control device 428. The completion of the current path causes current to flow, and then the receiver (not shown) can detect the presence of current and identify that the system 420 has been activated and the desired event is occurring or has occurred.

In one embodiment, two different materials 424, 426 are functionally similar for a DC power source, such as a battery, for the two electrodes required. A conductive liquid is used as the required electrolyte to complete the power supply. The completed power source is defined by the physicochemical reaction between the different materials 424, 426 of system 420 and the fluid surrounding the body. A completed power source can be considered a power source that utilizes a conductive solution in ions or like gastric fluid, blood or other body fluids, and certain tissues. Further, the environment may be something other than the body, and the liquid may be any electrically conductive liquid. For example, the electrically conductive liquid can be a brine or a metal based coating.

In a particular orientation, two different materials 424, 426 are shielded from the surrounding environment by an additional layer of material. Accordingly, when the shield is decomposed and two different materials 424, 426 are exposed to the target location, a voltage potential is generated.

In a particular aspect, the completed power source or supply is one of an active electrode material, an electrolyte, and an inactive material, such as a current collector, package. The active material is any pair of materials having different electrochemical potentials. Suitable materials are not limited to metals, and in particular embodiments, the pair of materials are selected from the group consisting of metals and non-metals, for example, a pair of metals (such as magnesium) and salts (such as copper iodide). About active electrode It is preferred that the pair of materials - metals, salts or intercalation compounds - have suitably different electrochemical potentials (voltages) and low interface resistances.

A variety of different materials can be utilized as the material for forming the electrodes. In a particular embodiment, the electrode material is selected to provide a voltage at the time of contact with the target physiological location (eg, the stomach) sufficient to drive the identification code. In a particular embodiment, the voltage provided by the electrode material when in contact with the metal at the target physiological location is 0.001 volts or more, including 0.01 volts or more, such as 0.1 volts or more, for example, 0.3 volts. Or higher, including 0.5 volts or higher, and including 1.0 volts or higher, wherein in certain embodiments, the voltage ranges from about 0.001 to about 10 volts, such as from about 0.01 to about 10 volts.

Referring also to FIG. 4, different materials 424, 426 provide a voltage potential to activate control device 428. Once the control device 428 is activated or energized, the control device 428 can change the conductivity between the first and second materials 424, 426 in a unique manner. By varying the conductivity between the first and second materials 424, 426, the control device 428 can control the intensity of the current through the conductive liquid surrounding the system 420. This produces a unique current signature that can be detected and measured by a receiver (not shown) that can be positioned in the body or outside the body. The receiver is disclosed in more detail in U.S. Patent Application Serial No. 12/673,326, filed on Dec. The entire contents thereof are hereby incorporated by reference. In addition to controlling the strength of the current path between materials, Conductive materials, films or "skirts" are used to increase the "length" of the current path and, therefore, act to enhance the conduction path as disclosed in the application for "IN-BODY DEVICE" dated September 25, 2008. U.S. Patent Application Serial No. 12/238,345, the entire disclosure of which is incorporated herein by reference. Or, in view of the disclosure herein, the words "non-conductive material", "film" and "skirt" and the word "current path extender" are used interchangeably and do not affect the scope or the embodiment and Apply for a patent scope. The skirts shown in sections 425, 427, respectively, can be associated, for example, to frame 422. The various shapes and configurations for the skirt are considered to fall within the scope of the various aspects of the present invention. For example, system 420 can be completely or partially surrounded by a skirt, and the skirt can be positioned along a central axis of system 420 or off-center relative to the central axis. Accordingly, the scope of the invention as claimed herein is not limited by the shape or size of the skirt. Moreover, in other embodiments, the different materials 424, 426 can be separated by a skirt that is positioned in an area defined between any of the different materials 424, 426.

System 420 can be grounded through a ground contact. System 420 can also include a sensor module. In operation, an ion or current path is established between the first material 424 to the second material 426 and is in contact with the system 420 through the conductive fluid. The voltage potential established between the first and second materials 424, 426 is established by a chemical reaction between the first and second materials 424, 426 and the conductive fluid. In one orientation, the surface of the first material 424 is not planar but an irregular surface. The irregular surface increases the surface area of the material and thus increases the area in contact with the electrically conductive fluid.

In one aspect, at the surface of the first material 424, a chemical reaction is between the material 424 and the surrounding conductive fluid such that the mass is released into the conductive fluid. The word quality (rnass) as used herein refers to protons and neutrons that form a substance. An example includes the moment when the material is copper chloride and when contacted with a conductive fluid, the copper chloride becomes copper (solid) and chloride ions in solution. The ion current entering the conductive fluid is via an ion path. In a similar manner, the chemical reaction is between the second material 426 and the surrounding conductive fluid, and the ions are captured by the second material 426. The release of ions at the first material 424 and the capture of ions by the second material 426 are collectively referred to as ion exchange. The rate of ion exchange, and the consequent ion emission rate or flow regime, is controlled by control unit 428. Control device 428 can increase or decrease the ion flow rate by varying the conductivity between the first and second materials 424, 426, which changes the impedance. Through the control of ion exchange, system 420 can encode information during the ion exchange process. Thus, system 420 uses ion emission to encode information in ion exchange.

Control device 428 can vary the duration of the fixed ion exchange rate or current intensity while maintaining a near constant rate or intensity similar to when the frequency is modulated and the amplitude is constant. Similarly, control device 428 can vary the number of stages of ion exchange rate or the intensity of the current while maintaining a duration that is close to a constant. Thus, control device 428 encodes information in current or ion exchange using various combinations of varying durations and varying rates or intensities. For example, the control device 428 can be used, but is not limited to any of the following technologies, that is, binary phase shift keying (Binary) Phase-Shift Keying (PSK), Frequency Modulation (FM), Amplitude Modulation (AM), On-Off Keying, and Phase Shift Keying with On-Off Keying ( PSK).

The various aspects of system 420 can include electronic components that are part of control device 428. Components that can be presented include, but are not limited to, logic and/or memory components, integrated circuits, inductors, resistors, and sensors for measuring various parameters. Each component can be secured to the frame and/or to another component. The components on the supported surface can be laid out in any convenient configuration. The interconnect can be placed where two or more components are presented on the surface of the solid support.

System 420 controls the conductivity between different materials and thus controls the ion exchange rate or current. By changing conductivity in a specific way, the system is able to encode information in ion exchange and current markers. Ion exchange or current markers are used to uniquely identify a particular system. In addition, system 420 can generate a variety of different unique exchanges or tokens and thus provide additional information. For example, a second current signature based on the second conductivity change pattern can be used to provide additional information, wherein the information can relate to the physical environment. To further illustrate, the first current sign can be a very low current state that maintains an oscillator on the wafer, and the second current sign can be a current state that is ten times higher than the current associated with the first current sign. At least one factor in the state.

Figures 5 through 10 show various aspects of a wearable wireless device. Re-wearable wireless devices include reusable components and disposable components. Reusable components typically include an electronic module and a power source. Disposable component It generally includes skin electrodes and skin adhesives.

The electronic module is a durable component, indicating that its life span exceeds the life of some or all of the remaining components. Electronic modules can last up to several years. A skin adhesive is a consumable component that has a lifespan that is less than its useful life and that has a lifespan that is less than the life of the durable component. The general life span of skin adhesives can range from less than 24 hours to 14 days or more. The skin electrodes and power source can be durable or consumable components, depending on the technology selected to implement these components. The life span of the skin electrode can range from less than 24 hours to several years depending on its type. The power source can have a life of less than 24 hours to several years depending on the type. Electronic modules, electrodes and power supplies are considered to be electrical or electronic components. The wearable wireless device also includes a further feature, device for interconnecting electronic components.

Re-wearable wireless devices allow users to replace consumable components, allow high cost components, and durable components to be used repeatedly, reducing the overall cost of system use. Figures 5 through 10 show three aspects of a wearable wireless device: a snap module, a cover module, and a cable module.

5 through 7 illustrate a face of a snap-fit type of re-wearable wireless device that includes a reusable component and a disposable component that is configured to be secured to a user via an adhesive layer. FIG. 5 shows a face of a disposable assembly 500 that includes an adhesive substrate 502, electrodes 504a, 504b (shown in phantom), electrical contacts 506a, 506b, and a mechanical snap connection mechanism 508. Electrodes 504a, 504b are electrically coupled to electrical contacts 506a, 506b. The mechanical snap connection mechanism 508 includes a protruding member that protrudes toward the central portion of the mechanical snap connection mechanism 508 at a correct angle. 510a, 510b.

6 is a perspective top plan view of one side of a reusable assembly 600 of an electronic module in a housing 602 that is configured to mate with a mechanical snap-fit connection 508 of the disposable assembly 500 shown in FIG. The outer casing 602 of the reusable assembly 600 includes recesses 604a, 604b (not shown) formed within the outer casing 602 for engaging the protruding members 510a, 510b, respectively, such that the reusable assembly 600 snaps into the mechanical snap connection mechanism 508. And thus was retained.

FIG. 7 is a perspective bottom view of a face of the reusable assembly 600. The bottom 606 of the reusable assembly 600 includes electrical contacts 702a, 702b that are configured to be electrically coupled to electrical contacts 506a, 506b in the mechanical snap connection mechanism 508. Accordingly, the electronic signals detected by electrodes 504a, 504b are coupled to the electronic modules of the reusable components via electrical contacts 702a, 702b. The electronic module is positioned in the outer casing 602 of the reusable assembly 600. The electronic module is functionally equivalent to the electronic module shown in Figures 2 to 3. In addition, the bottom 606 of the reusable component 600 can also include a communication channel input/output (I/O) address 704a and a personal identification number (PIN) 704b that uniquely identifies the electronic module of the reusable component 600. Modern wireless communication between the two devices requires the exchange of addresses and personal identification numbers to establish a connection. An input/output (I/O) address and personal identification number (PIN) 608 can be placed on the label, printed directly on the bottom 606 of the housing 602 or other locations, or any other suitable manner.

The reusable component 600 including the electronic module is a durable device, and the adhesive substrate 502 and the electrodes 504a, 504b are consumable. Electricity Source-battery - can be consumable or durable. If the battery is packaged in a skin-bonding substrate 502 envelope, it is consumable. Lithium manganese button cells are typically used to match the capacity to ensure that the battery life is comparable to the skin bonding substrate 502. Alternatively, the battery can be a durable component that is encapsulated by an electronic module. A rechargeable battery can be used and the device used to charge the battery must be provided - whether through the connector or via the induction coil. Since the electronic module is otherwise low in energy consumption, the primary battery can also be used, and the primary battery clearly provides a larger energy density than the secondary battery. The electronics for connecting the disposable assembly 500 and the reusable assembly 600 are provided by electrical spring contacts 506a, 506b, 702a, 702b that are each integrated into the assembly.

The disposable assembly 500 can be constructed of flexible circuitry for interconnecting and forming electrodes 504a, 504b with one or more hydrocolloids. The outer casing 602 of the reusable assembly 600 includes a plastic component and provides means for latching the electronic module onto the bonded substrate 502, and the entire reusable assembly 600 is received by the closed cell foam. The skin-bonding substrate 502 may be of a composite type having a hydro-colloid and acrylic type as the primary binder, which is configured to hold the re-wearable wireless device when the hydrocolloid is activated, and also to prevent the water colloid from seeping out. The side of the wearable wireless device.

8 and 9 show a face of a re-wearable wireless device that includes a reusable component 800 and a disposable component 900 configured to be secured to a user via an adhesive cover layer 902. FIG. 8 shows one face of the reusable component 800, and FIG. 9 shows one face of the adhesive cover layer 902. Durable reusable group in the wearable wireless device shown in Figures 8 and 9 The piece 800 includes an electronic module, skin electrodes 802a, 802b, and a power supply form, and the disposable assembly 900 has only a skin adhesive cover layer 902. There is no electrical interconnection outside of the reusable component 800. The power supply can be implemented as generally described in the snap-in modules of Figures 5-7. The electrodes 802a, 802b can be dry or capacitive. In this case, the skin adhesive cover 902 can comprise a 3-piece composite having a central section 904 configured to hold the reusable assembly 800 including the electronic module in place (but not establishing a viscous on the module) ) a hydrocolloid for primary skin adhesion and acrylic acid having the above functions.

FIG. 10 shows a face of a wearable wireless device that includes a reusable component 1000 and a disposable component 1002. Electrodes 1004a, 1004b are attached to the body. The electrodes 1004a, 1004b are attached to the electronic module of the reusable component 1000 via corresponding electrode terminals 1006a, 1006b. The wearable wireless device is shown in Figure 10, in which case the electronic module and power supply are durable. Skin electrodes and adhesives are consumable. The electronic module and power source are packaged in the housing 1008 of the reusable assembly 1000 such that it is adhered to the garment of the subject or other wear rather than the skin through the adhesive. This is most commonly achieved by spring clips, but other means such as Velcro or adhesive can be used. As shown in FIG. 10, general electrocardiographic electrodes 1004a, 1004b can be used in conjunction with an electronic module to form a re-slipable wireless device. Alternatively, electrodes 1004a, 1004b can be integrated into a single unit that ensures proper spacing of electrodes 1004a, 1004b. The interconnection between the electrodes 1004a, 1004b and the electronic module is coupled to the corresponding electrode terminal 1006a, 1006b biconductor cables 1010a, 1010b are provided. The connector 1012 is coupled to a socket in the electronic module, or the connection can be fixed. Connector 1012 can be placed at both ends of the cable.

Figure 11 shows a face of the bonded substrate 1100 that will be secured to the body. Adhesive substrate 1100 can be used in conjunction with any of the re-wearable wireless devices disclosed herein. The viscosity and adhesion length of any adhesive-based wearable device can be affected by varying degrees of sensitivity, different skin types, degree of activity, and body shape of the subject. Accordingly, in one aspect, the adhesive substrate 1100 includes a bonding system that, regardless of the user's variation, is comfortable to wear while not irritating to the user's skin, is not too long, and remains attached to the design life. And for easy application by the user to the user.

In one aspect, an adhesive substrate 1100 for a reusable wearable device is provided with an adhesive system that uses two different adhesive layers 1102, 1104 to achieve these functionalities. The primary adhesive layer 1102 is a hydrocolloid adhesive layer that is known to be very mild to the user's skin and can be easily tolerated by most users for a period of time greater than about 7 days. However, the primary adhesive layer 1102 does not have the most durable attachment to the skin and is susceptible to excessive water absorption. A secondary adhesive layer 1104 is used to partially cover the primary adhesive layer 1102 to create a perimeter of the primary adhesive layer 1102 surrounding the hydrocolloid base. The secondary adhesive layer 1104 is configured to have a strong adhesion to the skin and to keep the edges 1106 of the bonded substrate 1100 from peeling off from the skin. In one aspect, the primary adhesive layer 1102 is dispensed to a surface area greater than the surface area to which the secondary adhesive layer 1104 is dispensed. Secondary minor Adhesive layer 1104 is the key to long wear time. If the perimeter remains intact, the patch can remain attached for about 7 days to about 14 days.

As noted above, each user and their activity can affect the viscosity of the perimeter 1106 of the adhesive layer. Thus, the adhesive substrate 1100 can be used as a disposable component of a reusable wearable device that includes a hydrocolloid-based primary adhesive layer 1102 component and a secondary adhesive layer 1104 component that is added to the secondary adhesive layer 1104 component. The wearable device is then used to establish an edge seal and attach the adhesive substrate 1100 to the user. The secondary bonding layer 1104 can be an acrylic or cyanoacrylate if a more durable bond is used. Other secondary bonding layers 1104 can be employed without limitation. The secondary adhesive layer 1104 can be provided to the body as an accessory. Each reusable wearable device can be provided with a plurality of secondary adhesive layers 1104 strips to allow for a simple replacement and reattachment of the reusable wearable device. The secondary adhesive layer 1104 can also be provided with different degrees of tack and different numbers of bonded surface areas to suit different application needs. This will allow the reusable wearable device to be worn and used for up to the time that the battery will be allowed according to the plan. In one aspect, the bonded substrate 1100 can be employed and configured to be used with the reusable wearable device shown in Figures 5-7. In other aspects, with the addition of overlay portion 1108, shown in dashed lines to indicate selectivity, adhesive substrate 1100 can be employed and configured to work with the reusable wearable devices shown in Figures 8-9. use.

In various aspects, the disposable component reusable components can be interconnected by various suitable techniques throughout the reusable wearable devices described in Figures 1, 2 and 6 through 12 of the present invention. For example, can be abandoned Components and reusable components can be achieved by stripe connectors, surface mount technology (SMT) battery connectors, honeycomb/mobile phone battery connector concepts, curved batteries connected to EM, and non-directionality using conductive rubber Sealed connections, commercially known as hook-and-loop connectors for daughter-and-make bonding and daughter-in-mold, and plug-in connectors for simple electrode surface trajectories included on disposable components, wherein the ends of the thyristor The part enters the module, and the head of the thyristor is interconnected as an electrode.

FIG. 12A is a diagram showing a process of capturing an image of a communication channel input/output (I/O) address 1204a and a personal identification number (PIN) 1204b at the bottom 1202 of the reusable component 1200. In a particular aspect, a reusable wearable wireless device such as reusable component 1200 may not include a set of mobile phone chips, as previously described, and may only include short range radios to provide wireless communication. In such an embodiment, the short range radio system in the electronic module of the reusable component 1200 is configured to exchange information with the regional mobile phone or other regional wireless communication device to access the cellular network 108, the Internet. The network 112, the wide area network of the other network 110, accesses the remote server 106, as described in FIG. In order for the two devices to communicate without interference, the short-range radio in the electronic module of the reusable component 1200 must be paired with the regional mobile phone. Most modern wireless communications between the two devices require the exchange of I/O address 1204a and personal identification number 1204b to establish an authenticated encrypted link. This example is a Bluetooth where the address uniquely identifies the device in an environment in which many similar devices can be operated. This is why many people can use different Bluetooth headsets without interference while in the same room. Personal identification number 1204b adds some security to prevent fraudulent use of hardware devices, such as headphones, to make secret calls. Accordingly, the reusable component 1200 of the wearable wireless device includes an I/O address 1204a and a personal identification number 1204b associated with the short range radio.

In accordance with various aspects of the present invention, the reusable component 1200 equipped with a short range radio can use wireless connections to download data from the cellular network 108 and from other networks 110 or the Internet 112 to which it is connected, such as This is described in conjunction with the detailed discussion of FIG. Although Bluetooth is currently a universal and widely available short-range radio wireless standard available for mobile phones, it is expected that future standards, such as BLE, may be prevalent. Accordingly, the invention should not be limited by this.

In one aspect, the electronic module of the reusable component 1200 can be paired to a mobile phone to enable the electronic module to access the external network 108, 110, 112 or remote server 106. This communication can be run weekly, assuming that the reusable component 1200 has a life of at least one week. Currently, in order to make the wireless portable device visible, the main body is given the task of starting the wireless portable device to the mobile phone by pressing an external push button switch, so that the wireless portable device is exposed. Once the button is pressed, the short range radio broadcasts its I/O address 1204a and personal identification number 1204b to the devices within range. The subject then manually selects the I/O address from the list of devices found in the area and copies the personal identification number 1204b from the tag 1214 on the wearable electronic module (or from its packaging) and uses the mobile phone. The button/keyboard inputs it to the phone and establishes an encrypted link between the devices based on this. Due to the I/O address 1204a and the personal identification number 1204b Manual input techniques are inherently prone to errors and failures, and I/O address 1204a and personal identification number 1204b are incorrectly entered and pairing fails. Alternatively, based on the broadcast of the I/O address 1204a, an unencrypted link can be established between the two devices and used to exchange the personal identification code 1204b. Personal identification code 1204b is used to establish an encrypted link that is used for further communication. The risk is that the exchange of personal identification number 1204b can be intercepted and the secure link may be affected.

To overcome the specific limitations of this manual process, a new technology is provided in one aspect, as shown in Figure 12B, in which camera phone 1210 is used to capture image 1212 of I/O address 1204a and selectively capture the personal identification number. 1204b. The I/O address 1204a and optionally the personal identification code 1204b are located on the reusable component 1200 in the form of a logo identifiable by a machine, human, or a combination thereof. As shown in FIG. 12, the I/O address and personal identification code are placed on the label attached to the bottom 1202 of the reusable component 1200. It will be understood that most modern mobile phones (smart phones) include a relatively high resolution built-in image sensor/camera, and for a very powerful computing device, the smart phone 1210 (or a suitable mobile phone) is equipped with A built-in camera, and thus, can be used to capture the I/O address and image 1212 of the personal identification number 1204.

In one aspect of the proposed pairing scheme, the body 104 uses the camera of the smart phone 1210 to capture the image 1212 of the tag 1214 on the reusable component 1200. Tag 1214 may have both device I/O address 1204a and personal identification code 1204b printed thereon or only personal identification code 1204b. Printing can be human readable characters or can be machine readable words Yuan, like a bar code or a quick response (QR) code. The pairing software application running on the smart phone 1210 uses an optical character recognition (OCR) algorithm to convert the captured image 1212 into a data-device I/O address 1204a and/or a personal identification code 1204b, thus The OCR software extracts the personal identification number from the captured image 1212. Applications can also use graphical recognition algorithms to help operators diagnose errors during the pairing process. For example, if the label or device profile is too small in the imaging range, then the camera is too far from the device. If no label or device outline is recognized, then the reusable component 1200 is not in front of the camera of the smart phone 1210, or a camera that is too close to the smart phone 1210. Once the smartphone 1210 retrieves the I/O address 1204a and the personal identification number 1204b for the reusable component 1200, the pairing can be done securely without further manual intervention by the subject 104.

The receiver can include a signal receiver component that functions to receive a conductive transmit signal, such as a signal transmitted by an identifier of the swallowable event marker. The signal receiver can include a variety of different types of signal receiving components, wherein the nature of the receiver components must vary depending on the nature of the signals produced by the signal generating components. In a particular aspect, the signal receiver component can include one or more electrodes for detecting signals transmitted by signal generating components, such as two or more electrodes, three or more electrodes, and the like. In a particular aspect, the receiver device can be provided with two or three electrodes that are mutually dispersed at some distance. This distance allows the electrode to detect the differential voltage. This distance can vary from 0.1 cm to 1 meter in a particular orientation, like 0.1 to 5 cm, like 0.5 to 2.5 cm, In some cases, the distance is 1 cm.

An example of the external signal receiver facing the receiver of interest is shown in FIG. Figure 13 shows a receiver 1001 configured to be positioned at an external local location of the subject, such as the chest region. The receiver includes an upper housing plate 1110 (which may be fabricated, for example, from a suitable polymeric material) and includes a manually pressable operating button 1020 and a status identification code LED 1030 that can be used to convey to the viewer that the receiver is functioning. The manually pressurizable operation button 1020 can be manually operated to receive it from the storage mode to the non-storage mode. When the receiver is in the storage mode, the receiver's microcontroller can remain in a low duty cycle enable state to process the input from the on/off button and the receiver's digital signal processor (DSP) is turned off. When the switch button is pressed to open the receiver, the microcontroller removes the bounce input and provides power to the DSP to enter its idle state. When in the storage mode, the device may consume less than 10 μA of current including 5 μA or less, such as 1 μA or less, and includes 0.1 μA or less. This configuration allows the device to remain at greater than 90% of the usable battery life if stored for 1 month (assuming a 250mAH battery is present). This button can also be used for other purposes. For example, such buttons can be used to instruct the receiver to retrieve a particular type of data. Additionally or alternatively, such a button can be used to manually instruct the receiver to transmit data to another device.

Figure 14 provides an exploded view of the receiver shown in Figure 13. As shown in FIG. 14, the receiver 1001 includes an upper casing plate 1110, a rechargeable battery 1101, an integrated circuit assembly 1120, and a lower casing plate. 1130. The lower housing plate 1130 is snapped into the upper housing plate 1110 to seal the battery 1101 and the integrated circuit assembly 1120 in the fluid tight housing. Although the snap-in interaction is illustrated, any convenient matching scheme can be used so that the upper and lower housing plates can be held together by the inner locking groove, can be held together by a suitable adhesive, and can be welded together. and many more. In some examples, the electronic components can be molded into the upper and/or lower housing panels. Also shown is a viscous patch 1140 that is secured into the upper housing panel 1110 and includes conductive posts 1141, 1142, and 1143 that act as electrode contacts to the body during use of the receiver. In the receiver, the inter-pillars 1141, 1142, and 1143 are in electrical contact with the integrated circuit assembly 1120, such as through a cable or other electrically conductive member associated with the upper housing 1150. In one example, upper housing plate 1110 includes a conductive member configured to receive posts 1141, 1142, and 1143 coupled between cables (not shown), which in turn provides an electrical connection to integrated circuit assembly 1120.

FIG. 15 provides an exploded view of the adhesive patch 1140. The viscous patch 1140 includes upper pillars 1141, 1142, and 1143, as described above. These columns are in a state of being in electrical contact with the skin contact columns 1151, 1152, and 1153. On the skin side surface of the skin contact columns 1151, 1152, and 1153 is a conductive hydrocolloid layer 1154. Around each of the columns 1151, 1152, and 1153 are non-conductive hydrocolloids 1155 and pressure sensitive adhesive 1156 components. In this section, any convenient physiologically acceptable binder can be used. In some instances, an adhesive that responds to additional stimuli to alter its adhesive properties is used. For example, in light (for example, UV light) or Adhesives that become less viscous under the application of a substance can be used such that the adhesive remains strong as it is desired to keep the receiver in contact with the body, but is easily attenuated when needed, To facilitate the removal of the receiver from the body. On the non-skin side of each skin contact column is a layer of dry electrode material, for example, silver/silver chloride. On the upper surface of this layer of dry electrode material is a porous layer, for example, a carbon vinyl layer. Also shown is the upper support layer 1180. Although not shown, the upper pillars 1141, 1142, and 1143 are electrically connected to the dry electrode and skin contact pillars positioned below each of the upper pillars via the upper support layer 1180 (eg, urethane and polyethylene). As shown, the inter-pillar is eccentric with respect to its dry electrode layer in the direction of the outer edge of the patch, in a manner sufficient to increase the dipole size between any two designated inter-pillars. Additionally, a conductive gradient can be associated with each of the inter-columns as needed, for example, by changing the pattern of the porous layer 1170 and/or modifying the composition of the dry electrode layer. An interest in these aspects is that the conductivity of the conductive gradient increases in the direction of the outer edge of the patch.

Figures 16A through 16E provide various views of an additional external patch configuration 1300 that includes two electrodes 1310 and 1320 in an elastic structure having an adhesive strap configuration. The patch 1300 includes an upper elastic outer support 1330 and a lower elastic support 1350 that are fitted together as shown in FIG. 16E to surround the integrated circuit/battery assembly 1360 and the electrodes 1310 and 1320. As shown in Fig. 16D, the bottom surfaces of the electrodes 1310 and 1320 are exposed. As shown in FIG. 16E, electrodes 1310 and 1320 include lead elements 1375 and 1370 that provide electrical contact between the electrodes and integrated circuit/battery assembly 1360. Any convenient adhesive component can be used, like These are the ones described above.

It is to be noted that any reference to "a" or "an" is intended to mean that a particular feature, structure, or characteristic described in connection with the aspect is included in at least one aspect. Therefore, the statements "in one aspect" or "in the face" appearing in various places throughout the specification do not necessarily mean the same aspect. Furthermore, the particular features, structures, or characteristics may be combined in one or more aspects in any suitable manner.

Some of the words "coupled" and "connected" and their derivatives are described. It should be understood that these terms are not intended as synonyms for each other. For example, some aspects may be described using the term "connected" to indicate that two or more elements are in direct physical or electrical contact with each other. In other instances, some aspects may be described using the word "coupled" to indicate that two or more elements are in direct physical or electrical contact with each other. However, the word "coupled" may also mean that two or more elements are not in direct contact with each other, but still cooperate or influence each other.

Many modifications, substitutions, changes and equivalents will be apparent to those skilled in the art in the art. Therefore, it is to be understood that the appended claims are intended to cover all such modifications and

100‧‧‧Wireless system

102‧‧‧Reshaptable wireless devices

104‧‧‧ Living

106‧‧‧Remote node (remote server)

108‧‧‧Hive Communication Network

110‧‧‧Other networks

112‧‧‧Internet

114‧‧‧Mobile Signal Tower

116‧‧‧Base Station (BS)

118‧‧‧Database

120‧‧‧Processing system

Claims (28)

A re-wearable wireless device comprising: a reusable component configured to be secured to a disposable component, the reusable component comprising: a sensor interface configured to be configured to be secured to at least a living body An electrode receives the signal and monitors one or more physiological and physical parameters associated with the living body; and a cellular wireless communication circuit. The disposable wearable device of claim 1, further comprising the disposable component. The re-wearable wireless device of claim 2, wherein the disposable component comprises the at least one electrode. A re-wearable wireless device according to claim 3, wherein the disposable component comprises a mechanical snap-fit connection for receiving the reusable component therein. A re-wearable wireless device according to claim 4, wherein the reusable component comprises a housing and a recess formed in the housing for coupling with the mechanical snap-fit connection. The re-wearable wireless device of claim 4, wherein the mechanical snap connection mechanism comprises first and second protruding elements. The re-wearable wireless device of claim 4, wherein the mechanical snap connection mechanism comprises at least one electrical contact electrically coupled to the at least one electrode. For example, the re-wearable wireless device of claim 2, Wherein, the disposable device comprises an adhesive layer bonded to the living body. The re-wearable wireless device of claim 1, wherein the reusable component comprises at least one electrical contact electrically coupled to the at least one electrode. The re-wearable wireless device of claim 1, wherein the reusable component comprises the at least one electrode. The re-wearable wireless device of claim 10, further comprising a disposable component, wherein the disposable component comprises a cover layer, the cover layer comprising: a non-adhesive portion configured to cover the reusable component And the adhesive portion, configured to be bonded to the living body. The re-wearable wireless device of claim 2, wherein the reusable component comprises an electrical plug socket to electrically couple the at least one electrode to the reusable component. The re-wearable wireless device of claim 2, wherein the disposable component comprises: a first adhesive layer; and a second adhesive layer partially covering the first adhesive around a periphery of the first adhesive layer a layer, wherein the first adhesive layer comprises a first adhesive, and the second adhesive layer comprises a second adhesive. A wearable adhesive substrate for a wireless device, comprising: a first adhesive layer; The second adhesive layer partially covers the first adhesive layer around the periphery of the first adhesive layer, wherein the first adhesive layer comprises a first adhesive, and the second adhesive layer comprises a second adhesive. The re-wearable adhesive substrate for a wireless device according to claim 14, wherein the first adhesive layer is a mild skin adhesive, and the second adhesive layer is more durable than the first adhesive. Adhesive. The re-wearable adhesive substrate for a wireless device of claim 15, wherein the first adhesive comprises a hydrocolloid-based adhesive, and the second adhesive comprises an acrylic-based adhesive. A wearable adhesive substrate for a wireless device according to claim 16, wherein the second adhesive comprises a cyanoacrylate based adhesive. A re-wearable adhesive substrate for a wireless device according to claim 15 wherein the first adhesive covers a larger surface area than that covered by the second adhesive. A method for establishing a connection between two wireless devices, comprising: providing a first wireless device having a flag indicating a communication channel address identification; and capturing an image of the flag by a mobile phone computing device including an image sensor; And processing the captured image to extract the communication channel address identification represented by the flag. A method for establishing a connection between two wireless devices, as in claim 19, comprising: providing the first wireless device with a flag indicating a personal identification code communication channel address identification; and processing the captured image, To extract the personal identification code represented by the logo. A method of establishing a link between two wireless devices, as in claim 20, wherein the flag representing the personal identification code is in a human readable form, and processing comprises performing an optics by a processor of the mobile phone computing device The character recognizes the machine readable code and extracts text information representing the personal identification number. A method of establishing a link between two wireless devices, as in claim 20, wherein the flag representing the personal identification code is in a machine readable form, and processing comprises executing a barcode by a processor of the mobile phone computing device Identifying the machine readable code and extracting textual information representing the personal identification number. A method of establishing a link between two wireless devices, as in claim 20, wherein the flag representing the personal identification code is in a machine readable form, and processing comprises executing by the processor of the mobile phone computing device The response (QR) code identifies the machine readable code and extracts information representative of the personal identification number. A method of establishing a link between two wireless devices, as in claim 20, comprising using the extracted communication channel address representation represented by the flag and the extracted personal identification by a secure encrypted link The code is paired with the first and second wireless communication devices. A method of establishing a connection between two wireless devices, as in claim 19, wherein the flag indicating the communication channel address identification is in a human readable form, and processing comprises a processor by the mobile phone computing device The optical character recognition machine readable code is executed, and the text information indicating the address recognition of the communication channel is extracted. A method of establishing a link between two wireless devices as set forth in claim 19, wherein the flag indicating the communication channel address identification is in a machine readable form, and processing is performed by a processor of the mobile phone computing device. The barcode is executed to identify the machine readable code, and the text information indicating the address recognition of the communication channel is extracted. A method of establishing a connection between two wireless devices, as in claim 19, wherein the flag indicating the communication channel address identification is in a machine readable form, and processing includes a processor by the mobile phone computing device The fast response (QR) code is used to identify the machine readable code, and the text information indicating the address recognition of the communication channel is extracted. A method of establishing a connection between two wireless devices as set forth in claim 19, comprising pairing the first and second wireless communication devices with the extracted communication channel address identification represented by the flag.