TR200102129T2 - Karbamat ve karbazat ketolid antibiyotikleri. - Google Patents

Karbamat ve karbazat ketolid antibiyotikleri.

Info

Publication number
TR200102129T2
TR200102129T2 TR2001/02129T TR200102129T TR200102129T2 TR 200102129 T2 TR200102129 T2 TR 200102129T2 TR 2001/02129 T TR2001/02129 T TR 2001/02129T TR 200102129 T TR200102129 T TR 200102129T TR 200102129 T2 TR200102129 T2 TR 200102129T2
Authority
TR
Turkey
Prior art keywords
compounds
formula
ketolid
carbazate
carbamate
Prior art date
Application number
TR2001/02129T
Other languages
English (en)
Inventor
Kaneko Takushi
Su Wei-Guo
Wu Young-Jin
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of TR200102129T2 publication Critical patent/TR200102129T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

Abstract

Bu bulus, formül (I)'in bilesimleri ve onlarin farmasötik olarak uygun tuzlari ve çözeltileri ile ilgilidir, burada X1, X2, R2, R15, R16 ve R6 burada tanimlandigi gibidir. Formül (I)'in bilesimleri, çesitli bakteryal ve protozoal enfeksiyonlari ve bu tür enfeksiyonlarla ilgili bozukluklari tedavi etmek için kullanilabilecek antibakteryal ve antiprotozoal maddelerdir. Bulus ayrica formül (I)'in bilesimlerini içeren farmasötik kompozisyonlar ve formül (I)'in bilesimleri uygulanarak bakteryal ve protozoal enfeksiyonun tedavi metodudur.
TR2001/02129T 1998-12-10 1999-11-12 Karbamat ve karbazat ketolid antibiyotikleri. TR200102129T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11172898P 1998-12-10 1998-12-10

Publications (1)

Publication Number Publication Date
TR200102129T2 true TR200102129T2 (tr) 2002-01-21

Family

ID=22340138

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/02129T TR200102129T2 (tr) 1998-12-10 1999-11-12 Karbamat ve karbazat ketolid antibiyotikleri.

Country Status (13)

Country Link
US (1) US6664238B1 (tr)
EP (1) EP1137654A1 (tr)
AT (1) ATE344269T1 (tr)
AU (1) AU6484199A (tr)
DE (1) DE69933897T2 (tr)
ES (1) ES2273964T3 (tr)
GT (1) GT199900208A (tr)
MA (1) MA26711A1 (tr)
PA (1) PA8486401A1 (tr)
PE (1) PE20001297A1 (tr)
TN (1) TNSN99227A1 (tr)
TR (1) TR200102129T2 (tr)
WO (1) WO2000034297A1 (tr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE298761T1 (de) 1998-09-22 2005-07-15 Pfizer Prod Inc Carbamat- und carbazatketolidantibiotika
ID30233A (id) * 1999-01-27 2001-11-15 Pfizer Prod Inc Antibiotika ketolida
WO2000062783A2 (en) 1999-04-16 2000-10-26 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
US6451768B1 (en) 1999-04-16 2002-09-17 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
US6514944B2 (en) 1999-04-16 2003-02-04 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6939861B2 (en) 1999-04-16 2005-09-06 Kosan Biosciences, Inc. Amido macrolides
ATE340183T1 (de) 1999-04-16 2006-10-15 Kosan Biosciences Inc Antiinfektiöse makrolidderivate
EP1638549A4 (en) 2003-03-10 2011-06-15 Optimer Pharmaceuticals Inc NEW ANTIBACTERIAL AGENTS
US7419962B2 (en) * 2004-12-07 2008-09-02 Enanta Pharmaceuticals, Inc. 3,6-bicyclolides
AU2005317735B2 (en) * 2004-12-21 2009-06-04 Pfizer Products Inc. Macrolides
CN1318441C (zh) * 2005-04-25 2007-05-30 中国医学科学院医药生物技术研究所 大环内酯类抗生素的酮内酯化合物及其制备方法和用途
US20090005325A1 (en) * 2005-11-23 2009-01-01 Biswajit Bas Ketolide Derivatives as Antibacterial Agents
EP2214484A4 (en) * 2007-10-25 2013-01-02 Cempra Pharmaceuticals Inc PROCESS FOR PREPARING ANTIBACTERIAL MAKROLIDE AGENTS
US8796232B2 (en) * 2008-10-24 2014-08-05 Cempra Pharmaceuticals, Inc. Methods for treating resistant diseases using triazole containing macrolides
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
AU2010292010B2 (en) 2009-09-10 2016-01-07 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and MAC diseases
CN103080122A (zh) 2010-03-22 2013-05-01 森普拉制药公司 大环内脂的结晶形式及其用途
US9051346B2 (en) 2010-05-20 2015-06-09 Cempra Pharmaceuticals, Inc. Process for preparing triazole-containing ketolide antibiotics
JP6042334B2 (ja) 2010-09-10 2016-12-14 センプラ ファーマシューティカルズ，インコーポレイテッド 疾患治療のための水素結合形成フルオロケトライド
CN104470527B (zh) 2012-03-27 2019-05-28 森普拉制药公司 用于施用大环内酯抗生素的肠胃外制剂
WO2014152326A1 (en) 2013-03-14 2014-09-25 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
US9751908B2 (en) 2013-03-15 2017-09-05 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents
CN114437154B (zh) * 2022-01-30 2024-03-01 北京理工大学 一种含有喹诺酮的酮内酯衍生物及其制备方法和应用

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI8110592A8 (en) 1981-03-06 1996-06-30 Pliva Pharm & Chem Works Process for preparing of n-methyl-11-aza-10-deoxo-10-dihydroerythromycine a and derivatives thereof
US4474768A (en) 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
IL114589A (en) 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of the history of erythromycin
US5527780A (en) 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
FR2718450B1 (fr) 1994-04-08 1997-01-10 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2719587B1 (fr) 1994-05-03 1996-07-12 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2727969B1 (fr) 1994-12-09 1997-01-17 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2732684B1 (fr) 1995-04-06 1997-04-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2742757B1 (fr) 1995-12-22 1998-01-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
DE19626036A1 (de) 1996-06-28 1998-01-02 Whitaker Corp Optischer Steckverbinder
FR2751656B1 (fr) * 1996-07-24 1998-10-16 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
CN1238777A (zh) 1996-11-27 1999-12-15 大正制药株式会社 红霉素a衍生物
FR2757168B1 (fr) * 1996-12-12 1999-06-11 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
US5794778A (en) 1997-02-26 1998-08-18 Riverwood International Corporation Article carrier with strap-type handle and top panel access
HN1998000159A (es) * 1997-10-29 1999-02-09 Monsanto Co Derivados de 9- amino - 3 ceto eritromicina
FR2771008B1 (fr) * 1997-11-17 2000-04-28 Hoechst Marion Roussel Inc Utilisation des ketolides pour la preparation de compositions pharmaceutiques destinees a prevenir les complications thrombotiques arterielles liees a l'atherosclerose
AP1060A (en) 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
JP4573925B2 (ja) * 1998-07-09 2010-11-04 アベンティス・ファーマ・ソシエテ・アノニム 新規のエリスロマイシン誘導体、その製造方法及びその薬剤としての使用
FR2789392B1 (fr) * 1999-02-04 2001-10-05 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments

Also Published As

Publication number Publication date
ES2273964T3 (es) 2007-05-16
PA8486401A1 (es) 2003-01-24
GT199900208A (es) 2001-05-31
WO2000034297A1 (en) 2000-06-15
DE69933897T2 (de) 2007-03-15
US6664238B1 (en) 2003-12-16
MA26711A1 (fr) 2004-12-20
TNSN99227A1 (fr) 2005-11-10
AU6484199A (en) 2000-06-26
PE20001297A1 (es) 2000-12-04
ATE344269T1 (de) 2006-11-15
DE69933897D1 (de) 2006-12-14
EP1137654A1 (en) 2001-10-04

Similar Documents

Publication Publication Date Title
TR200102129T2 (tr) Karbamat ve karbazat ketolid antibiyotikleri.
EA200100623A1 (ru) Кетолидные антибиотики
CA2292359A1 (en) Novel azalides and methods of making same
AP2001002131A0 (en) Novel macrolide antibiotics.
TR200400630T4 (tr) Ketolit antibiyotikleri
CA2331297A1 (en) Hygromycin a derivatives
PT1167376E (pt) Antibioticos macrolidos
CA2331261A1 (en) 2"-deoxy hygromycin derivatives
CA2352332A1 (en) Hygromycin a derivatives
MXPA02011966A (es) Derivados de higromicina a para el el tratamiento de infecciones bacterianas y por protozoarios.
BG106635A (en) Hygromycin a prodrugs
EP1749832A3 (en) Carbamate and carbazate ketolide antibiotics
ECSP993235A (es) Antibioticos cetolidos carbamato y carbazato