TH108799B - New ortho-amino anilides for cancer therapy - Google Patents
New ortho-amino anilides for cancer therapyInfo
- Publication number
- TH108799B TH108799B TH901004170A TH0901004170A TH108799B TH 108799 B TH108799 B TH 108799B TH 901004170 A TH901004170 A TH 901004170A TH 0901004170 A TH0901004170 A TH 0901004170A TH 108799 B TH108799 B TH 108799B
- Authority
- TH
- Thailand
- Prior art keywords
- anilides
- amino
- cancer therapy
- new ortho
- compounds
- Prior art date
Links
- 201000011510 cancer Diseases 0.000 title abstract 2
- 238000002560 therapeutic procedure Methods 0.000 title abstract 2
- 229940051881 Anilide analgesics and antipyretics Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims abstract 3
- 125000000217 alkyl group Chemical group 0.000 claims 3
- 229910052736 halogen Inorganic materials 0.000 claims 2
- 150000002367 halogens Chemical group 0.000 claims 2
- 125000003545 alkoxy group Chemical group 0.000 claims 1
- 125000004093 cyano group Chemical group *C#N 0.000 claims 1
- 125000000753 cycloalkyl group Chemical group 0.000 claims 1
- 125000000623 heterocyclic group Chemical group 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 125000004435 hydrogen atoms Chemical group [H]* 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 241001465754 Metazoa Species 0.000 abstract 1
- -1 compounds Compound Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drugs Drugs 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
- 238000000844 transformation Methods 0.000 abstract 1
- 230000001131 transforming Effects 0.000 abstract 1
Abstract
การประดิษฐ์ปัจจุบันถูกมุ่งตรงไปยังสารประกอบของสูตร (สูตร) (I), โดยที่ R1 ถึง R5 มีนัยสำคัญซึ่งถูกกำหนดในกรณีนี้, ไปยังกระบวนการสำหรับประดิษฐ์กรรม ของสารประกอบดังหล่าวเช่นเดียวกันกับยาที่ประกอบด้วยสารประกอบดังกล่าว สารประกอบตามการ ประดิษฐ์นี้แสดงกิจกรรมที่ต้านการเพิ่มจำนวนและที่เหนี่ยวนำการเปลี่ยนสภาพ และดังนั้นเป็น ประโยชน์สำหรับการบำบัดของโรค เช่น มะเร็ง ในมนุษย์หรือสัตว์ The present invention is directed towards the compound of the formula (I), where R1 to R5 is significant which is defined in this case, to the process for fabricating. Of such compounds as well as drugs containing such compounds Compound according to This invention demonstrates activities that resist proliferation and induce transformations. And so is Useful for the therapy of diseases such as cancer in humans or animals
Claims (1)
Publications (2)
Publication Number | Publication Date |
---|---|
TH108799A TH108799A (en) | 2011-06-24 |
TH108799B true TH108799B (en) | 2011-06-24 |
Family
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