SI1745064T1 - Compounds for proteasome enzyme inhibition - Google Patents

Compounds for proteasome enzyme inhibition

Info

Publication number
SI1745064T1
SI1745064T1 SI200531248T SI200531248T SI1745064T1 SI 1745064 T1 SI1745064 T1 SI 1745064T1 SI 200531248 T SI200531248 T SI 200531248T SI 200531248 T SI200531248 T SI 200531248T SI 1745064 T1 SI1745064 T1 SI 1745064T1
Authority
SI
Slovenia
Prior art keywords
compounds
enzyme inhibition
proteasome enzyme
proteasome
inhibition
Prior art date
Application number
SI200531248T
Other languages
Slovenian (sl)
Inventor
Mark S Smyth
Guy J Laidig
Ronald T Borchardt
Barry A Bunin
Craig M Crews
John H Musser
John Clifford Chabala
Original Assignee
Proteolix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Proteolix Inc filed Critical Proteolix Inc
Priority claimed from PCT/US2005/012740 external-priority patent/WO2005105827A2/en
Publication of SI1745064T1 publication Critical patent/SI1745064T1/en

Links

SI200531248T 2004-04-15 2005-04-14 Compounds for proteasome enzyme inhibition SI1745064T1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US56234004P 2004-04-15 2004-04-15
US56909604P 2004-05-07 2004-05-07
US59940104P 2004-08-06 2004-08-06
US61000104P 2004-09-14 2004-09-14
US61000204P 2004-09-14 2004-09-14
US61015904P 2004-09-14 2004-09-14
US62057304P 2004-10-20 2004-10-20
PCT/US2005/012740 WO2005105827A2 (en) 2004-04-15 2005-04-14 Compounds for proteasome enzyme inhibition
EP05735686A EP1745064B1 (en) 2004-04-15 2005-04-14 Compounds for proteasome enzyme inhibition

Publications (1)

Publication Number Publication Date
SI1745064T1 true SI1745064T1 (en) 2011-05-31

Family

ID=38704582

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200531248T SI1745064T1 (en) 2004-04-15 2005-04-14 Compounds for proteasome enzyme inhibition

Country Status (3)

Country Link
CN (1) CN101006098B (en)
ES (1) ES2358268T3 (en)
SI (1) SI1745064T1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8367617B2 (en) * 2007-10-04 2013-02-05 Onyx Therapeutics, Inc. Crystalline peptide epoxy ketone protease inhibitors and the synthesis of amino acid keto-epoxides
GB0914883D0 (en) 2009-08-26 2009-09-30 Univ Belfast Compound
CN109096370B (en) * 2012-07-26 2022-03-18 圣特莱国际公司 Polypeptide epoxy ketone compound
CN103641890B (en) * 2013-12-19 2015-08-19 重庆泰濠制药有限公司 The synthetic method of a kind of Ka Feizuo meter
CN104844540A (en) * 2015-05-18 2015-08-19 上海凯欣生物医药科技有限公司 New crystal form of (2S)-2-aomni group-4-methyl-1-[(2R)-2-methyl epoxy ethyl]-1-pentanone trifluoroacetic acid salt and preparation method thereof
CN105440106A (en) * 2015-12-17 2016-03-30 昆明贵研药业有限公司 Preparation method of carfilzomib
US11078231B2 (en) * 2016-09-14 2021-08-03 Fresenius Kabi Oncology Ltd Process for purification of carfilzomib intermediate

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6831099B1 (en) * 1999-05-12 2004-12-14 Yale University Enzyme inhibition
EP1477180A1 (en) * 1999-10-20 2004-11-17 Osteoscreen, Inc. Inhibitors of proteasomal activity for stimulating bone and hair growth

Also Published As

Publication number Publication date
CN101006098B (en) 2014-10-29
CN101006098A (en) 2007-07-25
ES2358268T3 (en) 2011-05-09

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