SG167657A1 - Novel medicament compositions based on tiotropium salts and on salmeterol salts - Google Patents

Novel medicament compositions based on tiotropium salts and on salmeterol salts

Info

Publication number
SG167657A1
SG167657A1 SG200505149-5A SG2005051495A SG167657A1 SG 167657 A1 SG167657 A1 SG 167657A1 SG 2005051495 A SG2005051495 A SG 2005051495A SG 167657 A1 SG167657 A1 SG 167657A1
Authority
SG
Singapore
Prior art keywords
salts
salmeterol
compositions based
tiotropium
medicament compositions
Prior art date
Application number
SG200505149-5A
Inventor
Nagel Juergen
Schmelzer Christel
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of SG167657A1 publication Critical patent/SG167657A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The present invention relates to novel pharmaceutical compositions based on tiotropium salts and salts of salmeterol, processes for preparing them and their use in the treatment of respiratory diseases. No suitable figure
SG200505149-5A 2000-11-13 2001-11-09 Novel medicament compositions based on tiotropium salts and on salmeterol salts SG167657A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10056104A DE10056104A1 (en) 2000-11-13 2000-11-13 Drug compositions useful for treatment of respiratory diseases, especially asthma and chronic obstructive pulmonary disease comprises tiotropium salts and salmeterol salts

Publications (1)

Publication Number Publication Date
SG167657A1 true SG167657A1 (en) 2011-01-28

Family

ID=7663071

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200505149-5A SG167657A1 (en) 2000-11-13 2001-11-09 Novel medicament compositions based on tiotropium salts and on salmeterol salts

Country Status (32)

Country Link
EP (3) EP1335728B1 (en)
JP (2) JP4282322B2 (en)
KR (2) KR100940752B1 (en)
CN (1) CN1678318A (en)
AT (2) ATE362761T1 (en)
AU (3) AU2791002A (en)
BG (1) BG107781A (en)
BR (1) BR0115226A (en)
CA (1) CA2429012A1 (en)
CY (1) CY1106774T1 (en)
CZ (1) CZ20031444A3 (en)
DE (3) DE10056104A1 (en)
DK (2) DK1514546T3 (en)
EA (1) EA007904B1 (en)
EC (1) ECSP034571A (en)
EE (1) EE200300228A (en)
ES (2) ES2240549T3 (en)
HR (1) HRP20030378A2 (en)
HU (1) HUP0301447A3 (en)
IL (2) IL155718A0 (en)
MX (1) MXPA03004164A (en)
NO (1) NO20032111L (en)
NZ (1) NZ526400A (en)
PL (1) PL205330B1 (en)
PT (2) PT1335728E (en)
RS (2) RS50286B (en)
SG (1) SG167657A1 (en)
SI (2) SI1335728T1 (en)
SK (2) SK286939B6 (en)
UA (1) UA74853C2 (en)
WO (1) WO2002038154A1 (en)
ZA (1) ZA200302921B (en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2165768B1 (en) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa NEW DERIVATIVES OF QUINUCLIDINE AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.
US7214687B2 (en) 1999-07-14 2007-05-08 Almirall Ag Quinuclidine derivatives and medicinal compositions containing the same
EP1231894B1 (en) * 1999-11-23 2005-01-12 Glaxo Group Limited Pharmaceutical formulations of salmeterol
WO2003024452A1 (en) * 2001-09-14 2003-03-27 Boehringer Ingelheim Pharma Gmbh & Co. Kg Novel medicaments for inhalation
DE10214263A1 (en) * 2002-03-28 2003-10-16 Boehringer Ingelheim Pharma HFA suspension formulations containing an anticholinergic
US7311894B2 (en) 2002-03-28 2007-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg HFA suspension formulations containing an anticholinergic
US7244415B2 (en) 2002-03-28 2007-07-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg HFA suspension formulations of an anhydrate
US7250426B2 (en) 2002-11-29 2007-07-31 Boehringer Ingelheim Pharma Gmbh & Co Kg Tiotropium-containing pharmaceutical combination for inhalation
DE10256080A1 (en) * 2002-11-29 2004-06-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Combination medicinal product for inhalation containing tiotropium
PL375868A1 (en) * 2002-12-16 2005-12-12 Boehringer Ingelheim Pharma Gmbh & Co.Kg Tiotropium containing hfc solution formulations
DE10351663A1 (en) * 2002-12-20 2004-07-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Stable, accurately dosable inhalable powder medicament for treating asthma or chronic obstructive pulmonary disease, containing tiotropium, specific form of salmeterol xinafoate and auxiliary
DE10345065A1 (en) * 2003-09-26 2005-04-14 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosol formulation for inhalation containing an anticholinergic
EP2336127A1 (en) * 2003-11-03 2011-06-22 Boehringer Ingelheim International GmbH Tiotropium salts, method for creating same and medicinal formulations containing same
ES2342468T3 (en) * 2003-11-03 2010-07-07 Boehringer Ingelheim International Gmbh PROCEDURE FOR THE PREPARATION OF TIOTROPE SALTS.
ATE474601T1 (en) * 2004-05-31 2010-08-15 Almirall Sa COMBINATIONS WITH ANTIMUSCARINE ACTIVES AND PDE4 INHIBITORS
ES2257152B1 (en) 2004-05-31 2007-07-01 Laboratorios Almirall S.A. COMBINATIONS THAT INCLUDE ANTIMUSCARINIC AGENTS AND BETA-ADRENERGIC AGONISTS.
WO2006117299A2 (en) 2005-05-02 2006-11-09 Boehringer Ingelheim International Gmbh Novel crystalline forms of tiotropium bromide
CA2617897A1 (en) * 2005-08-06 2007-02-15 Boehringer Ingelheim International Gmbh Method for the treatment of dyspnea comprising combined administration of tiotropium salts and salts of salmeterol
ES2298049B1 (en) 2006-07-21 2009-10-20 Laboratorios Almirall S.A. PROCEDURE FOR MANUFACTURING BROMIDE OF 3 (R) - (2-HIDROXI-2,2-DITIEN-2-ILACETOXI) -1- (3-PHENOXIPROPIL) -1-AZONIABICICLO (2.2.2) OCTANO.
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
US20120220557A1 (en) * 2011-02-17 2012-08-30 Chiesi Farmaceutici S.P.A. Liquid propellant-free formulation comprising an antimuscarinic drug
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients
WO2013127738A1 (en) * 2012-02-28 2013-09-06 Boehringer Ingelheim International Gmbh Novel propellant-gas-containing tiotropium formulation
WO2015065222A1 (en) * 2013-10-28 2015-05-07 Шолекс Девелопмент Гмбх Pharmaceutical inhaled drug with micronized tiotropium bromide as active ingredient for the treatment of bronchial asthma and chronic obstructive pulmonary disease and method for producing same
TW201835041A (en) 2017-02-17 2018-10-01 印度商托仁特生技有限公司 Compounds with Beta-Adrenergic Agonist and Antimuscarinic Activity
WO2019142214A1 (en) * 2018-01-19 2019-07-25 Cipla Limited Pharmaceutical composition comprising tiotropium for inhalation
CN111936124A (en) * 2018-07-26 2020-11-13 四川海思科制药有限公司 Aerosol pharmaceutical composition containing glycopyrronium salt and indacaterol salt, and preparation method and application thereof
WO2020019953A1 (en) * 2018-07-26 2020-01-30 四川海思科制药有限公司 Aerosol pharmaceutical composition containing a glycopyrrolate salt, preparation method therefor, and uses thereof
WO2022119661A1 (en) * 2020-12-04 2022-06-09 Tygrus, LLC THERAPEUTIC MATERIAL WITH LOW pH AND LOW TOXICITY ACTIVE AGAINST AT LEAST ONE PATHOGEN FOR ADDRESSING PATIENTS WITH RESPIRATORY ILLNESSES
US11826382B2 (en) 2020-05-01 2023-11-28 Tygrus, LLC Therapeutic material with low pH and low toxicity active against at least one pathogen for addressing patients with respiratory illnesses
US11642372B2 (en) 2020-05-01 2023-05-09 Tygrus, LLC Therapeutic material with low pH and low toxicity active against at least one pathogen for addressing patients with respiratory illnesses

Citations (1)

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Publication number Priority date Publication date Assignee Title
DE19847971A1 (en) * 1998-10-17 1999-09-02 Schiering Filter fire occurrence prevention method

Family Cites Families (5)

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ES2234266T3 (en) * 1998-07-24 2005-06-16 Jago Research Ag MEDICAL FORMULATIONS FOR AEROSOLS.
DE19835346A1 (en) * 1998-08-05 2000-02-10 Boehringer Ingelheim Pharma Two-part capsule for pharmaceutical preparations for powder inhalers
DE19847970A1 (en) * 1998-10-17 2000-04-20 Boehringer Ingelheim Pharma Stable concentrated liquid formulation of inhalable drug, e.g. formoterol or salbutamol, in solution or suspension medium, used after dilution for treatment of respiratory disorders by inhalation
DE19921693A1 (en) * 1999-05-12 2000-11-16 Boehringer Ingelheim Pharma Pharmaceutical composition for treating respiratory disorders, e.g. asthma, comprises combination of anticholinergic and beta-mimetic agents having synergistic bronchospasmolytic activity and reduced side-effects
DE19961300A1 (en) * 1999-12-18 2001-06-21 Asta Medica Ag Storage system for medicinal products in powder form and inhaler equipped with them

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
DE19847971A1 (en) * 1998-10-17 1999-09-02 Schiering Filter fire occurrence prevention method

Non-Patent Citations (1)

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Title
CHRONIC OBSTRUCTIVE PULMONARY DISEASE: NEW OPPORTUNITIES FOR DRUG DEVELOPMENT *

Also Published As

Publication number Publication date
DE10056104A1 (en) 2002-05-23
EP1808174A1 (en) 2007-07-18
EA200300503A1 (en) 2004-12-30
ES2287629T3 (en) 2007-12-16
EE200300228A (en) 2003-10-15
DE50112535D1 (en) 2007-07-05
HRP20030378A2 (en) 2005-04-30
CN1678318A (en) 2005-10-05
JP2004513146A (en) 2004-04-30
YU35503A (en) 2006-05-25
NO20032111D0 (en) 2003-05-12
PT1335728E (en) 2005-05-31
BR0115226A (en) 2003-10-07
JP2005068163A (en) 2005-03-17
MXPA03004164A (en) 2005-08-16
JP4282594B2 (en) 2009-06-24
DK1514546T3 (en) 2007-09-24
EP1514546A1 (en) 2005-03-16
HUP0301447A3 (en) 2007-10-29
DK1335728T3 (en) 2005-04-18
KR20030065509A (en) 2003-08-06
KR100886094B1 (en) 2009-02-27
AU2002227910B2 (en) 2007-03-01
PL205330B1 (en) 2010-04-30
BG107781A (en) 2004-06-30
CY1106774T1 (en) 2012-05-23
IL155718A (en) 2010-06-30
EP1335728A1 (en) 2003-08-20
EP1514546B1 (en) 2007-05-23
RS50286B (en) 2009-09-08
ATE291428T1 (en) 2005-04-15
KR100940752B1 (en) 2010-02-11
DE50105729D1 (en) 2005-04-28
SI1514546T1 (en) 2007-10-31
EA007904B1 (en) 2007-02-27
JP4282322B2 (en) 2009-06-17
NZ526400A (en) 2005-09-30
RS20090105A (en) 2009-07-15
CZ20031444A3 (en) 2003-08-13
CA2429012A1 (en) 2002-05-16
AU2791002A (en) 2002-05-21
AU2007202303B2 (en) 2010-01-21
PT1514546E (en) 2007-06-15
EP1335728B1 (en) 2005-03-23
SK7412003A3 (en) 2003-10-07
KR20080079701A (en) 2008-09-01
WO2002038154A1 (en) 2002-05-16
AU2007202303A1 (en) 2007-06-14
SI1335728T1 (en) 2005-08-31
UA74853C2 (en) 2006-02-15
ES2240549T3 (en) 2005-10-16
IL155718A0 (en) 2003-11-23
ECSP034571A (en) 2003-06-25
HUP0301447A2 (en) 2003-10-28
ZA200302921B (en) 2004-04-19
NO20032111L (en) 2003-07-08
SK286950B6 (en) 2009-08-06
ATE362761T1 (en) 2007-06-15
PL365989A1 (en) 2005-01-24
SK286939B6 (en) 2009-07-06

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