SG11202110376XA - Heteroaryl derivative, method for producing the same, and pharmaceutical composition comprising same as effective component - Google Patents
Heteroaryl derivative, method for producing the same, and pharmaceutical composition comprising same as effective componentInfo
- Publication number
- SG11202110376XA SG11202110376XA SG11202110376XA SG11202110376XA SG11202110376XA SG 11202110376X A SG11202110376X A SG 11202110376XA SG 11202110376X A SG11202110376X A SG 11202110376XA SG 11202110376X A SG11202110376X A SG 11202110376XA SG 11202110376X A SG11202110376X A SG 11202110376XA
- Authority
- SG
- Singapore
- Prior art keywords
- same
- producing
- pharmaceutical composition
- effective component
- heteroaryl derivative
- Prior art date
Links
- 125000001072 heteroaryl group Chemical group 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5386—1,4-Oxazines, e.g. morpholine spiro-condensed or forming part of bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20190031269 | 2019-03-19 | ||
KR20190134472 | 2019-10-28 | ||
PCT/KR2020/095044 WO2020190119A1 (en) | 2019-03-19 | 2020-03-19 | Heteroaryl derivative, method for producing same, and pharmaceutical composition comprising same as effective component |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202110376XA true SG11202110376XA (en) | 2021-10-28 |
Family
ID=72521153
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202110376XA SG11202110376XA (en) | 2019-03-19 | 2020-03-19 | Heteroaryl derivative, method for producing the same, and pharmaceutical composition comprising same as effective component |
Country Status (15)
Country | Link |
---|---|
US (2) | US20220162203A1 (en) |
EP (1) | EP3943491A4 (en) |
JP (2) | JP7109013B2 (en) |
KR (2) | KR102318875B1 (en) |
CN (3) | CN114605400A (en) |
AU (2) | AU2020240382B2 (en) |
BR (1) | BR112021018704B1 (en) |
CA (1) | CA3134261A1 (en) |
IL (2) | IL299831A (en) |
MA (1) | MA55380A (en) |
MX (1) | MX2021011160A (en) |
NZ (1) | NZ781366A (en) |
SG (1) | SG11202110376XA (en) |
WO (1) | WO2020190119A1 (en) |
ZA (1) | ZA202107889B (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20220289733A1 (en) * | 2019-03-19 | 2022-09-15 | Voronoi Inc. | Heteroaryl derivative, method for producing same, and pharmaceutical composition comprising same as effective component |
JP7109013B2 (en) | 2019-03-19 | 2022-07-29 | ボロノイ インコーポレイテッド | Heteroaryl Derivatives, Methods for Producing Heteroaryl Derivatives, and Pharmaceutical Compositions Containing Heteroaryl Derivatives as Active Ingredients |
TW202227425A (en) * | 2020-09-18 | 2022-07-16 | 南韓商沃若諾伊生物公司 | Heteroaryl derivatives, preparation method for the same, and a pharmaceutical composition comprising the same as an active ingredient |
KR20220085735A (en) * | 2020-12-14 | 2022-06-22 | 보로노이바이오 주식회사 | Isoxazolidine derivative compounds, and uses thereof |
WO2022234965A1 (en) * | 2021-05-07 | 2022-11-10 | 주식회사 보로노이 | Heteroaryl derivative, method for preparing same, and pharmaceutical composition comprising same as active ingredient |
JP2024519626A (en) * | 2021-05-17 | 2024-05-21 | ボロノイ インコーポレイテッド | Heteroaryl derivative compounds and uses thereof |
KR102563834B1 (en) * | 2021-06-28 | 2023-08-04 | 순천대학교 산학협력단 | Novel compound for inducing apoptosis and composition for anticancer comprising the same |
WO2024096624A1 (en) * | 2022-11-03 | 2024-05-10 | Voronoi Inc. | Fumarate, tartrate, malate, and citrate salts of an egfr inhibitor |
WO2024097848A1 (en) | 2022-11-03 | 2024-05-10 | Oric Pharmaceuticals, Inc. | Malonate and glycolate salts of an egfr inhibitor |
Family Cites Families (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60134679D1 (en) | 2000-10-20 | 2008-08-14 | Eisai R&D Man Co Ltd | Nitrogen-containing aromatic heterocycles |
US8084457B2 (en) | 2003-09-15 | 2011-12-27 | Lead Discovery Center Gmbh | Pharmaceutically active 4,6-disubstituted aminopyrimidine derivatives as modulators of protein kinases |
WO2006125616A2 (en) | 2005-05-25 | 2006-11-30 | Ingenium Pharmaceuticals Ag | Pyrimidine-based cdk inhibitors for treating pain |
TW200804364A (en) | 2006-02-22 | 2008-01-16 | Boehringer Ingelheim Int | New compounds |
JP2010522188A (en) | 2007-03-20 | 2010-07-01 | スミスクライン ビーチャム コーポレーション | Compound |
TWI377944B (en) | 2007-06-05 | 2012-12-01 | Hanmi Holdings Co Ltd | Novel amide derivative for inhibiting the growth of cancer cells |
JP2011102241A (en) | 2008-03-04 | 2011-05-26 | Dainippon Sumitomo Pharma Co Ltd | Novel 1-aminocarbonylpiperidine derivative |
AU2010284255B2 (en) | 2009-08-17 | 2016-11-17 | Memorial Sloan-Kettering Cancer Center | Heat shock protein binding compounds, compositions, and methods for making and using same |
KR101401664B1 (en) | 2011-11-15 | 2014-06-11 | 중앙대학교 산학협력단 | Novel pyrimidine-2,4-diamine derivatives for differentiation of neural stem cells and medical use thereof |
ES2668479T3 (en) | 2012-01-20 | 2018-05-18 | Genosco | Substituted pyrimidine compounds and their use as SYK inhibitors |
US20150166591A1 (en) | 2012-05-05 | 2015-06-18 | Ariad Pharmaceuticals, Inc. | Methods and compositions for raf kinase mediated diseases |
WO2014055928A2 (en) | 2012-10-04 | 2014-04-10 | University Of Utah Research Foundation | Substituted n-(3-(pyrimidin-4-yl)phenyl)acrylamide analogs as tyrosine receptor kinase btk inhibitors |
EP2769722A1 (en) | 2013-02-22 | 2014-08-27 | Ruprecht-Karls-Universität Heidelberg | Compounds for use in inhibiting HIV capsid assembly |
US9434719B2 (en) | 2013-03-14 | 2016-09-06 | Novartis Ag | 3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH |
WO2015025936A1 (en) | 2013-08-22 | 2015-02-26 | 大鵬薬品工業株式会社 | Novel quinoline-substituted compound |
WO2015061247A2 (en) | 2013-10-21 | 2015-04-30 | Merck Patent Gmbh | Heteroaryl compounds as btk inhibitors and uses thereof |
KR20150047855A (en) | 2013-10-25 | 2015-05-06 | 한미약품 주식회사 | 2-cyano-acrylamide derivatives for inhibiting protein kinase |
EP3143015B1 (en) | 2014-05-13 | 2019-02-20 | ARIAD Pharmaceuticals, Inc. | Heteroaryl compounds for kinase inhibition |
DK3157916T3 (en) | 2014-06-19 | 2019-03-18 | Ariad Pharma Inc | HETEROARYL COMPOUNDS FOR CHINESE INHIBITION |
PL3205650T3 (en) * | 2014-10-11 | 2021-12-06 | Shanghai Hansoh Biomedical Co., Ltd. | Egfr inhibitor, and preparation and application thereof |
SG11201701960XA (en) | 2014-10-13 | 2017-04-27 | Yuhan Corp | Compounds and compositions for modulating egfr mutant kinase activities |
EP3206691B1 (en) * | 2014-10-14 | 2018-09-19 | Sunshine Lake Pharma Co., Ltd. | Substituted heteroaryl compounds and methods of use |
CN107835811B (en) | 2015-07-16 | 2019-11-08 | 正大天晴药业集团股份有限公司 | Aniline pyrimidine derivative and application thereof |
CN106478607B (en) * | 2015-08-28 | 2019-05-24 | 广东东阳光药业有限公司 | Substituted heteroaryl compound and combinations thereof and purposes |
CN106132957B (en) * | 2015-08-31 | 2018-06-12 | 无锡双良生物科技有限公司 | 2- arylamine yl pyridines, pyrimidine or pyrrolotriazine derivatives and its preparation method and application |
US10709692B2 (en) | 2015-12-04 | 2020-07-14 | Denali Therapeutics Inc. | Isoxazolidine derived inhibitors of receptor interacting protein kinase 1 (RIPK1) |
EP3399968B8 (en) * | 2016-01-07 | 2021-12-01 | Xuanzhu Biopharmaceutical Co., Ltd. | Selective inhibitors of clinically important mutants of the egfr tyrosine kinase |
US11203576B2 (en) | 2016-03-11 | 2021-12-21 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Aurora kinase and Janus kinase inhibitors for prevention of graft versus host disease |
US11072607B2 (en) | 2016-12-16 | 2021-07-27 | Genentech, Inc. | Inhibitors of RIP1 kinase and methods of use thereof |
JP7028900B2 (en) | 2017-06-13 | 2022-03-02 | ベイジン アダマドル バイオテクノロジー リミテッド ライアビリティ カンパニー | Aminopyrimidine compounds, their preparation methods, and their use |
CA3068854A1 (en) * | 2017-07-05 | 2019-01-10 | Cs Pharmatech Limited | Selective inhibitors of clinically important mutants of the egfr tyrosine kinase |
CA3079786A1 (en) | 2017-10-24 | 2019-05-02 | The Broad Institute, Inc. | 4h-pyrrolo[3,2-c]pyridin-4-one derivatives |
TWI798334B (en) | 2018-01-31 | 2023-04-11 | 大陸商迪哲(江蘇)醫藥股份有限公司 | Erbb/btk inhibitors |
CN108191774B (en) | 2018-01-31 | 2022-05-24 | 中国药科大学 | Heterocyclic compound, preparation method and application thereof |
KR20190108079A (en) | 2018-03-13 | 2019-09-23 | 보로노이바이오 주식회사 | 2,4,5-substituted pyrimidine derivatives, preparation method thereof, and pharmaceutical composition for use in preventing or treating cancer containing the same as an active ingredient |
WO2019177374A1 (en) | 2018-03-13 | 2019-09-19 | 포로노이바이오 주식회사 | 2, 4, 5-substituted pyrimidine derivative, preparation method therefor, and pharmaceutical composition comprising same as effective ingredient for prevention or treatment of cancer or inflammatory disease |
CA3099737A1 (en) | 2018-05-14 | 2019-11-21 | Ariad Pharmaceuticals, Inc. | Pharmaceutical salts of pyrimidine derivatives and method of treating disorders |
CN109280048A (en) | 2018-11-16 | 2019-01-29 | 江西科技师范大学 | A kind of pyrimidines of the structure of acrylamide containing substituted-phenyl and its application |
CN109608394A (en) | 2018-12-03 | 2019-04-12 | 湖南大学 | The synthetic method and azepine aromatic amine compounds of azepine aromatic amine compounds |
JP7109013B2 (en) | 2019-03-19 | 2022-07-29 | ボロノイ インコーポレイテッド | Heteroaryl Derivatives, Methods for Producing Heteroaryl Derivatives, and Pharmaceutical Compositions Containing Heteroaryl Derivatives as Active Ingredients |
-
2020
- 2020-03-19 JP JP2022504023A patent/JP7109013B2/en active Active
- 2020-03-19 WO PCT/KR2020/095044 patent/WO2020190119A1/en active Application Filing
- 2020-03-19 CN CN202210215237.6A patent/CN114605400A/en active Pending
- 2020-03-19 MA MA055380A patent/MA55380A/en unknown
- 2020-03-19 CN CN202211226875.4A patent/CN115838369A/en active Pending
- 2020-03-19 SG SG11202110376XA patent/SG11202110376XA/en unknown
- 2020-03-19 NZ NZ781366A patent/NZ781366A/en unknown
- 2020-03-19 US US17/440,630 patent/US20220162203A1/en active Pending
- 2020-03-19 BR BR112021018704-9A patent/BR112021018704B1/en active IP Right Grant
- 2020-03-19 KR KR1020200033737A patent/KR102318875B1/en active IP Right Grant
- 2020-03-19 MX MX2021011160A patent/MX2021011160A/en unknown
- 2020-03-19 CA CA3134261A patent/CA3134261A1/en active Pending
- 2020-03-19 IL IL299831A patent/IL299831A/en unknown
- 2020-03-19 CN CN202080022186.4A patent/CN113993866B/en active Active
- 2020-03-19 EP EP20774059.8A patent/EP3943491A4/en active Pending
- 2020-03-19 AU AU2020240382A patent/AU2020240382B2/en active Active
-
2021
- 2021-09-19 IL IL286471A patent/IL286471B2/en unknown
- 2021-10-15 ZA ZA2021/07889A patent/ZA202107889B/en unknown
- 2021-10-21 KR KR1020210141386A patent/KR102564533B1/en active IP Right Grant
- 2021-11-08 US US17/521,711 patent/US11466000B2/en active Active
-
2022
- 2022-07-07 JP JP2022109721A patent/JP7394298B2/en active Active
- 2022-08-01 AU AU2022211789A patent/AU2022211789A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
CN115838369A (en) | 2023-03-24 |
CN113993866A (en) | 2022-01-28 |
EP3943491A4 (en) | 2022-11-23 |
IL286471B2 (en) | 2023-08-01 |
MA55380A (en) | 2022-01-26 |
AU2020240382A1 (en) | 2021-11-11 |
EP3943491A1 (en) | 2022-01-26 |
AU2022211789A1 (en) | 2022-08-25 |
CN114605400A (en) | 2022-06-10 |
BR112021018704B1 (en) | 2023-01-10 |
AU2020240382B2 (en) | 2022-08-25 |
US20220073505A1 (en) | 2022-03-10 |
CN113993866B (en) | 2022-10-28 |
US11466000B2 (en) | 2022-10-11 |
JP2022522250A (en) | 2022-04-14 |
IL286471B1 (en) | 2023-04-01 |
ZA202107889B (en) | 2024-02-28 |
MX2021011160A (en) | 2022-02-10 |
IL286471A (en) | 2021-12-01 |
JP7109013B2 (en) | 2022-07-29 |
BR112021018704A2 (en) | 2021-11-23 |
US20220162203A1 (en) | 2022-05-26 |
IL299831A (en) | 2023-03-01 |
KR102564533B1 (en) | 2023-08-08 |
WO2020190119A1 (en) | 2020-09-24 |
KR20210130123A (en) | 2021-10-29 |
KR20200111644A (en) | 2020-09-29 |
CA3134261A1 (en) | 2020-09-24 |
JP2022125283A (en) | 2022-08-26 |
JP7394298B2 (en) | 2023-12-08 |
KR102318875B1 (en) | 2021-11-01 |
NZ781366A (en) | 2022-08-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL286471A (en) | Heteroaryl derivative, method for producing the same, and pharmaceutical composition comprising same as effective component | |
SG11202105850YA (en) | Diphenyl-like compound, intermediate thereof, preparation method therefor, pharmaceutical composition thereof and uses thereof | |
EP3511314A4 (en) | System for producing ester composition, and method for producing ester composition, using same | |
EP3312177A4 (en) | Tricyclic derivative compound, method for preparing same, and pharmaceutical composition comprising same | |
EP3587422A4 (en) | Pyrrolo-pyrimidine derivative compound, preparation method therefor, and pharmaceutical composition comprising same compound as effective ingredient for preventing or treating protein kinase-related disease | |
EP3580208A4 (en) | Novel heterocyclic compound, its preparation method, and pharmaceutical composition comprising the same | |
EP3687540A4 (en) | Heteroaryl compounds as cxcr4 inhibitors, composition and method using the same | |
EP3594312A4 (en) | Composition, method for producing same, and use thereof | |
EP3670511A4 (en) | Tetrahydroprotoberberine compound, preparation method therefor and uses thereof, and pharmaceutical composition | |
EP3908277A4 (en) | Heteroaryl compounds as necrosis inhibitors, composition and method using the same | |
HRP20200104T8 (en) | Novel heterocyclic compound, method for preparing the same, and pharmaceutical composition comprising the same | |
EP3808751A4 (en) | Camptothecin derivative, preparation method therefor and application thereof | |
IL286733A (en) | Compound, method and pharmaceutical composition for dux4 expression adjustment | |
IL285378A (en) | Heterocyclic compound, pharmaceutical composition comprising same, preparation method therefor, and use thereof | |
EP3636281A4 (en) | Method for treating depression, and pharmaceutical composition | |
EP3838898A4 (en) | Isoindolin-1-on derivative, method for preparing same, and pharmaceutical composition comprising same as effective component for preventing or treating cancer | |
EP3212640A4 (en) | Compound having gpr119 agonistic activity, method for preparing the same, and pharmaceutical composition including the same as effective component | |
EP3685845A4 (en) | Composition and method for producing same | |
EP3590341A4 (en) | Plant disease prevention composition and method for preventing plant disease using same | |
EP3604303A4 (en) | Novel pyrrolopyridine derivative, method for producing same, and use thereof | |
EP3650025A4 (en) | Pharmaceutical composition and method for preparing same | |
EP3705481A4 (en) | Heteroaryl amide compounds, preparation method therefor, pharmaceutical compositions thereof, and applications thereof | |
EP3689859A4 (en) | Method for preparing oxaspirocycle derivative, and intermediate thereof | |
EP3642193A4 (en) | Heteroaryl compounds as inhibitors of necrosis, composition and method using the same | |
EP4074716A4 (en) | Organopolysiloxane compound and method for producing the same, and composition including said compound |