SG11202100317YA - System and method for the production of biomolecules - Google Patents

System and method for the production of biomolecules

Info

Publication number
SG11202100317YA
SG11202100317YA SG11202100317YA SG11202100317YA SG11202100317YA SG 11202100317Y A SG11202100317Y A SG 11202100317YA SG 11202100317Y A SG11202100317Y A SG 11202100317YA SG 11202100317Y A SG11202100317Y A SG 11202100317YA SG 11202100317Y A SG11202100317Y A SG 11202100317YA
Authority
SG
Singapore
Prior art keywords
biomolecules
production
Prior art date
Application number
SG11202100317YA
Inventor
Bastien Mairesse
Viron Laetitia De
Alex Chatel
Original Assignee
Univercells Tech S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2018/076354 external-priority patent/WO2019072584A1/en
Application filed by Univercells Tech S A filed Critical Univercells Tech S A
Publication of SG11202100317YA publication Critical patent/SG11202100317YA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/10—Separation or concentration of fermentation products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/18—External loop; Means for reintroduction of fermented biomass or liquid percolate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/44—Means for regulation, monitoring, measurement or control, e.g. flow regulation of volume or liquid level
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
SG11202100317YA 2018-07-27 2019-06-27 System and method for the production of biomolecules SG11202100317YA (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201862711070P 2018-07-27 2018-07-27
PCT/EP2018/076354 WO2019072584A1 (en) 2017-09-27 2018-09-27 System and method for the production of biomolecules such as viral vaccines
US201962795820P 2019-01-23 2019-01-23
PCT/EP2019/067263 WO2020020569A1 (en) 2018-07-27 2019-06-27 System and method for the production of biomolecules

Publications (1)

Publication Number Publication Date
SG11202100317YA true SG11202100317YA (en) 2021-02-25

Family

ID=69182166

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202100317YA SG11202100317YA (en) 2018-07-27 2019-06-27 System and method for the production of biomolecules

Country Status (9)

Country Link
US (1) US20210155892A1 (en)
EP (1) EP3830235A1 (en)
JP (1) JP2021531767A (en)
KR (1) KR20210069032A (en)
CN (1) CN112912482A (en)
AU (1) AU2019309101A1 (en)
CA (1) CA3106661A1 (en)
SG (1) SG11202100317YA (en)
WO (1) WO2020020569A1 (en)

Families Citing this family (13)

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EP3613841B1 (en) 2014-03-25 2022-04-20 Terumo BCT, Inc. Passive replacement of media
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
US11965175B2 (en) 2016-05-25 2024-04-23 Terumo Bct, Inc. Cell expansion
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
EP4157988A2 (en) * 2020-05-29 2023-04-05 Univercells Technologies S.A. System and method for the production of biomolecules
US20230365909A1 (en) * 2020-08-21 2023-11-16 Univercells Technologies S.A. Biomass measuring system for fixed bed bioreactor and related methods
JP2023552726A (en) * 2020-11-23 2023-12-19 アベック，インコーポレイテッド Filtration systems, components, and methods
EP4330367A1 (en) 2021-04-29 2024-03-06 Univercells Technologies SA Systems and methods for the continuous production and purification of biologics
EP4347778A1 (en) * 2021-05-26 2024-04-10 Simabs NV Integrated continuous bioprocess production platform
US20220395770A1 (en) * 2021-06-10 2022-12-15 Levitronix Gmbh Device and a method for tangential flow filtration of a fluid
WO2023144266A1 (en) * 2022-01-26 2023-08-03 Univercells Technologies Sa Biomass prediction/estimation system based on parameter sensing for fixed bed bioreactor and related methods
WO2023194597A1 (en) * 2022-04-07 2023-10-12 Univercells Technologies Sa Modular bioreactor, bioreactor system and related methods

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EP0995483A1 (en) * 1998-10-23 2000-04-26 The Procter & Gamble Company A cross-flow filtration apparatus
US6214221B1 (en) * 1999-02-22 2001-04-10 Henry B. Kopf Method and apparatus for purification of biological substances
EP2380970B1 (en) * 2003-06-25 2017-12-20 Cytori Therapeutics, Inc. Systems and methods for separating and concentrating regenerative cells from tissue
DE102004032318B4 (en) * 2004-07-02 2015-08-20 Technische Hochschule Mittelhessen Production of a concentrated solution of biological substances
EP2379699B1 (en) * 2008-12-19 2017-12-13 Stobbe Tech A/S Device for industrial biolayer cultivation
FR2940145B1 (en) * 2008-12-24 2011-03-25 Millipore Corp TROLLEY AND INSTALLATION FOR TREATING A BIOLOGICAL LIQUID
EP2414508A4 (en) * 2009-04-03 2015-05-06 Xcellerex Inc Tissue and organ graft bioreactor and method of operation
US20110114556A1 (en) * 2009-11-10 2011-05-19 Biovantage Resources, Inc. Soft Fail Algae Growth System and Method
US20130115588A1 (en) * 2010-04-15 2013-05-09 G & G Technologies, Inc. Integrated bioreactor and separation system and methods of use therof
SG185434A1 (en) * 2010-05-11 2012-12-28 Artelis S A Apparatus and methods for cell culture
EP2644259A1 (en) * 2012-03-29 2013-10-02 Roche Diagniostics GmbH Micro flow filtration system and flow filtration method
US20130288228A1 (en) * 2012-04-28 2013-10-31 Arthur Anderson Methods and apparatuses for cultivating phototropic microorganisms
CN110172405A (en) * 2012-08-20 2019-08-27 泰尔茂比司特公司 The component of the fluid recycled across cell growth chamber is concentrated
CN104640973A (en) * 2012-09-27 2015-05-20 通用电气健康护理生物科学股份公司 Tangential flow perfusion system
US20140093952A1 (en) * 2012-10-02 2014-04-03 David Serway Bioreactor Tangential Flow Perfusion Filter System
US10711238B2 (en) * 2012-10-02 2020-07-14 Repligen Corporation Method for proliferation of cells within a bioreactor using a disposable pumphead and filter assembly
US10494421B2 (en) * 2014-02-10 2019-12-03 Univercells Nv System, apparatus and method for biomolecules production
BE1022439B1 (en) * 2014-02-10 2016-03-30 Univercells Sa APPARATUS SYSTEM AND METHOD FOR PRODUCING BIOMOLECULES
BE1024733B1 (en) * 2016-11-09 2018-06-14 Univercells Sa CELL GROWTH MATRIX

Also Published As

Publication number Publication date
CA3106661A1 (en) 2020-01-30
JP2021531767A (en) 2021-11-25
KR20210069032A (en) 2021-06-10
CN112912482A (en) 2021-06-04
EP3830235A1 (en) 2021-06-09
AU2019309101A1 (en) 2021-03-04
US20210155892A1 (en) 2021-05-27
WO2020020569A1 (en) 2020-01-30

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