SG11202011094PA - Method for preparing oligonucleic acid compound - Google Patents
Method for preparing oligonucleic acid compoundInfo
- Publication number
- SG11202011094PA SG11202011094PA SG11202011094PA SG11202011094PA SG11202011094PA SG 11202011094P A SG11202011094P A SG 11202011094PA SG 11202011094P A SG11202011094P A SG 11202011094PA SG 11202011094P A SG11202011094P A SG 11202011094PA SG 11202011094P A SG11202011094P A SG 11202011094PA
- Authority
- SG
- Singapore
- Prior art keywords
- preparing
- acid compound
- oligonucleic acid
- oligonucleic
- compound
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2018091231 | 2018-05-10 | ||
PCT/JP2019/018828 WO2019216433A1 (en) | 2018-05-10 | 2019-05-10 | Method for producing oligonucleic acid compound |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202011094PA true SG11202011094PA (en) | 2020-12-30 |
Family
ID=68468137
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202011094PA SG11202011094PA (en) | 2018-05-10 | 2019-05-10 | Method for preparing oligonucleic acid compound |
Country Status (9)
Country | Link |
---|---|
US (1) | US11560401B2 (en) |
EP (1) | EP3792269A4 (en) |
JP (1) | JP7394749B2 (en) |
KR (1) | KR20210008055A (en) |
CN (1) | CN112384520A (en) |
AU (1) | AU2019266768B2 (en) |
CA (1) | CA3099778A1 (en) |
SG (1) | SG11202011094PA (en) |
WO (1) | WO2019216433A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109851593B (en) * | 2019-02-01 | 2021-04-16 | 沈阳药科大学 | Triglyceride prodrug based on lymph-mediated transport and preparation method thereof |
WO2021095874A1 (en) * | 2019-11-13 | 2021-05-20 | 日本新薬株式会社 | Method for producing oligonucleic acid compound |
AU2022266379A1 (en) * | 2021-04-28 | 2023-11-09 | Nippon Shinyaku Co., Ltd. | Method for producing oligonucleic acid compound |
WO2023127918A1 (en) * | 2021-12-27 | 2023-07-06 | 日本新薬株式会社 | Method for producing oligonucleic acid compound |
WO2024096078A1 (en) * | 2022-11-04 | 2024-05-10 | 日本新薬株式会社 | Flow liquid separation device, flow liquid separation system, and production method for compound having phosphate bond |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2130844A5 (en) | 1971-03-23 | 1972-11-10 | Commissariat Energie Atomique | |
JPS5668388A (en) | 1979-11-10 | 1981-06-09 | Norin Suisansyo Shokuhin Sogo Kenkyusho | Production of cell body of spirulina algae |
WO1991009033A1 (en) | 1989-12-20 | 1991-06-27 | Anti-Gene Development Group | Uncharged morpholino-based polymers having phosphorous-containing chiral intersubunit linkages |
JP2005529957A (en) | 2002-06-13 | 2005-10-06 | ローディア インク. | Process for producing phosphorus diamidite compound |
US8067571B2 (en) * | 2005-07-13 | 2011-11-29 | Avi Biopharma, Inc. | Antibacterial antisense oligonucleotide and method |
SI2735568T1 (en) | 2006-05-10 | 2018-01-31 | Sarepta Therapeutics, Inc. | Oligonucleotide analogs having cationic intersubunit linkages |
KR100886139B1 (en) | 2007-11-13 | 2009-02-27 | 주식회사 삼천리제약 | Method for preparing oligonucleotide |
RU2606627C2 (en) | 2007-11-15 | 2017-01-10 | Серепта Терапьютикс,Инк. | Method for synthesis of morpholine oligomers |
JP5548852B2 (en) | 2009-05-29 | 2014-07-16 | 国立大学法人東京農工大学 | Hydrophobic group-bonded nucleoside, hydrophobic group-bonded nucleoside solution, and hydrophobic group-bonded oligonucleotide synthesis method |
US8969551B2 (en) * | 2010-09-30 | 2015-03-03 | Nippon Shinyaku Co., Ltd. | Morpholino nucleic acid derivatives |
JP5979139B2 (en) | 2011-05-17 | 2016-08-24 | 味の素株式会社 | Method for producing oligonucleotide |
US9278987B2 (en) * | 2011-11-18 | 2016-03-08 | Sarepta Therapeutics, Inc. | Functionally-modified oligonucleotides and subunits thereof |
EP3858847A1 (en) | 2011-11-30 | 2021-08-04 | Sarepta Therapeutics, Inc. | Oligonucleotides for treating expanded repeat diseases |
JP6237237B2 (en) | 2012-02-17 | 2017-11-29 | 味の素株式会社 | Base protected oligonucleotide |
ES2622716T3 (en) * | 2012-09-21 | 2017-07-07 | Osaka University | Oligonucleotide and artificial nucleoside in bridge with guanidine |
WO2014077292A1 (en) | 2012-11-14 | 2014-05-22 | 武田薬品工業株式会社 | Method for liquid-phase synthesis of nucleic acid |
JP6477464B2 (en) | 2013-05-24 | 2019-03-06 | 味の素株式会社 | Method for producing morpholino oligonucleotide |
WO2016060135A1 (en) * | 2014-10-14 | 2016-04-21 | 味の素株式会社 | Morpholino oligonucleotide manufacturing method |
WO2016140232A1 (en) | 2015-03-04 | 2016-09-09 | Jitsubo株式会社 | Peptide synthesis method |
-
2019
- 2019-05-10 EP EP19799887.5A patent/EP3792269A4/en active Pending
- 2019-05-10 KR KR1020207035458A patent/KR20210008055A/en active Search and Examination
- 2019-05-10 JP JP2020518368A patent/JP7394749B2/en active Active
- 2019-05-10 WO PCT/JP2019/018828 patent/WO2019216433A1/en active Application Filing
- 2019-05-10 CA CA3099778A patent/CA3099778A1/en active Pending
- 2019-05-10 SG SG11202011094PA patent/SG11202011094PA/en unknown
- 2019-05-10 AU AU2019266768A patent/AU2019266768B2/en active Active
- 2019-05-10 CN CN201980045979.5A patent/CN112384520A/en active Pending
- 2019-05-10 US US17/053,448 patent/US11560401B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US20210261596A1 (en) | 2021-08-26 |
US11560401B2 (en) | 2023-01-24 |
EP3792269A1 (en) | 2021-03-17 |
JP7394749B2 (en) | 2023-12-08 |
KR20210008055A (en) | 2021-01-20 |
EP3792269A4 (en) | 2022-06-22 |
JPWO2019216433A1 (en) | 2021-05-27 |
AU2019266768A1 (en) | 2020-12-17 |
WO2019216433A1 (en) | 2019-11-14 |
CA3099778A1 (en) | 2019-11-14 |
CN112384520A (en) | 2021-02-19 |
AU2019266768B2 (en) | 2024-02-29 |
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