SG11202006712XA - Treatment of ophthalmologic diseases - Google Patents
Treatment of ophthalmologic diseasesInfo
- Publication number
- SG11202006712XA SG11202006712XA SG11202006712XA SG11202006712XA SG11202006712XA SG 11202006712X A SG11202006712X A SG 11202006712XA SG 11202006712X A SG11202006712X A SG 11202006712XA SG 11202006712X A SG11202006712X A SG 11202006712XA SG 11202006712X A SG11202006712X A SG 11202006712XA
- Authority
- SG
- Singapore
- Prior art keywords
- treatment
- ophthalmologic diseases
- ophthalmologic
- diseases
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/35—Valency
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/71—Decreased effector function due to an Fc-modification
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Endocrinology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862627103P | 2018-02-06 | 2018-02-06 | |
| US201862729333P | 2018-09-10 | 2018-09-10 | |
| PCT/EP2019/052704 WO2019154776A1 (en) | 2018-02-06 | 2019-02-05 | Treatment of ophthalmologic diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202006712XA true SG11202006712XA (en) | 2020-08-28 |
Family
ID=65352014
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202006712XA SG11202006712XA (en) | 2018-02-06 | 2019-02-05 | Treatment of ophthalmologic diseases |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20210139576A1 (en) |
| EP (1) | EP3749359A1 (en) |
| JP (3) | JP7005772B2 (en) |
| KR (1) | KR20200119274A (en) |
| CN (1) | CN111699004A (en) |
| AU (1) | AU2019219004A1 (en) |
| CA (1) | CA3088355A1 (en) |
| IL (1) | IL276383B2 (en) |
| MX (1) | MX2020007527A (en) |
| SG (1) | SG11202006712XA (en) |
| TW (1) | TWI831764B (en) |
| WO (1) | WO2019154776A1 (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| RU2744860C2 (en) | 2015-12-30 | 2021-03-16 | Кодиак Сайенсиз Инк. | Antibodies and their conjugates |
| BR112020015074A2 (en) | 2018-01-26 | 2020-12-08 | The Regents Of The University Of California | METHODS AND COMPOSITIONS FOR TREATING ANGIOGENIC DISORDERS WITH THE USE OF ANTI-VEGF AGENTS |
| MX2022001433A (en) * | 2019-08-06 | 2022-02-22 | Hoffmann La Roche | Personalized treatment of ophthalmologic diseases. |
| CA3157509A1 (en) | 2019-10-10 | 2021-04-15 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
| CN114867487A (en) | 2019-11-25 | 2022-08-05 | 加利福尼亚大学董事会 | Long-acting VEGF inhibitors for intraocular neovascularization |
| KR20230061458A (en) * | 2020-09-04 | 2023-05-08 | 에프. 호프만-라 로슈 아게 | Antibodies that bind to VEGF-A and ANG2 and methods of use |
| TW202221027A (en) * | 2020-09-17 | 2022-06-01 | 大陸商江蘇恆瑞醫藥股份有限公司 | Bispecific antigen binding molecules that specifically bind to vegf and ang-2 |
| US20240158489A1 (en) * | 2021-03-30 | 2024-05-16 | Abpro Corporation | Methods for treating choroidal neovascularization using anti-ang2 x vegf multi-specific antibodies |
| CN117100845A (en) * | 2022-10-24 | 2023-11-24 | 景泽生物医药(合肥)股份有限公司 | Application of recombinant human Octoplasmin in preparing medicine for treating choroidal vascular diseases |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5202238A (en) | 1987-10-27 | 1993-04-13 | Oncogen | Production of chimeric antibodies by homologous recombination |
| US5204244A (en) | 1987-10-27 | 1993-04-20 | Oncogen | Production of chimeric antibodies by homologous recombination |
| US5731168A (en) | 1995-03-01 | 1998-03-24 | Genentech, Inc. | Method for making heteromultimeric polypeptides |
| SI1325932T1 (en) | 1997-04-07 | 2005-08-31 | Genentech Inc | |
| WO1998050431A2 (en) | 1997-05-02 | 1998-11-12 | Genentech, Inc. | A method for making multispecific antibodies having heteromultimeric and common components |
| ES2592271T3 (en) | 2005-03-31 | 2016-11-29 | Chugai Seiyaku Kabushiki Kaisha | Polypeptide production methods by regulating the association of polypeptides |
| DK1999154T3 (en) | 2006-03-24 | 2012-12-03 | Merck Patent Gmbh | MANUFACTURED HETERODIMERED PROTEIN DOMAINS |
| US20090182127A1 (en) | 2006-06-22 | 2009-07-16 | Novo Nordisk A/S | Production of Bispecific Antibodies |
| US8242247B2 (en) | 2007-12-21 | 2012-08-14 | Hoffmann-La Roche Inc. | Bivalent, bispecific antibodies |
| PT2235064E (en) | 2008-01-07 | 2016-03-01 | Amgen Inc | Method for making antibody fc-heterodimeric molecules using electrostatic steering effects |
| US8268314B2 (en) | 2008-10-08 | 2012-09-18 | Hoffmann-La Roche Inc. | Bispecific anti-VEGF/anti-ANG-2 antibodies |
| CN102459346B (en) | 2009-04-27 | 2016-10-26 | 昂考梅德药品有限公司 | The method manufacturing heteromultimers molecule |
| EP3112382A1 (en) | 2009-12-29 | 2017-01-04 | Emergent Product Development Seattle, LLC | Heterodimer binding proteins and uses thereof |
| AR080794A1 (en) | 2010-03-26 | 2012-05-09 | Hoffmann La Roche | BIVING SPECIFIC ANTIBODIES ANTI-VEGF / ANTI-ANG-2 |
| EP2569337A1 (en) | 2010-05-14 | 2013-03-20 | Rinat Neuroscience Corp. | Heterodimeric proteins and methods for producing and purifying them |
| MX352929B (en) | 2010-11-05 | 2017-12-13 | Zymeworks Inc | Stable heterodimeric antibody design with mutations in the fc domain. |
| MX349901B (en) * | 2011-01-13 | 2017-08-18 | Regeneron Pharma | Use of a vegf antagonist to treat angiogenic eye disorders. |
| US9527925B2 (en) | 2011-04-01 | 2016-12-27 | Boehringer Ingelheim International Gmbh | Bispecific binding molecules binding to VEGF and ANG2 |
| SI2794905T1 (en) | 2011-12-20 | 2020-08-31 | Medimmune, Llc | Modified polypeptides for bispecific antibody scaffolds |
| KR102171431B1 (en) | 2012-04-20 | 2020-10-30 | 메뤼스 엔.페. | Methods and means for the production of Ig-like molecules |
| WO2014009465A1 (en) * | 2012-07-13 | 2014-01-16 | Roche Glycart Ag | Bispecific anti-vegf/anti-ang-2 antibodies and their use in the treatment of ocular vascular diseases |
| EP2887958B1 (en) * | 2012-08-21 | 2021-05-19 | OPKO Pharmaceuticals, LLC | Liposome formulations |
| CN105164157B (en) | 2013-04-29 | 2024-05-28 | 豪夫迈·罗氏有限公司 | Modified asymmetric antibodies to FC-receptor binding and methods of use |
| KR20150063728A (en) | 2013-12-02 | 2015-06-10 | 삼성전자주식회사 | Anti-VEGF-C/anti-Ang2 bispecific antibody |
| TWI761959B (en) * | 2014-11-07 | 2022-04-21 | 瑞士商諾華公司 | Methods for treating ocular diseases |
| US20160144025A1 (en) * | 2014-11-25 | 2016-05-26 | Regeneron Pharmaceuticals, Inc. | Methods and formulations for treating vascular eye diseases |
| HRP20220066T1 (en) * | 2014-12-11 | 2022-04-15 | Bayer Healthcare Llc | Treatment of age related macular degeneration with a small active choroidal neovascularization lesion |
| AR103477A1 (en) * | 2015-01-28 | 2017-05-10 | Lilly Co Eli | VEGFA / ANG2 COMPOUNDS |
| US10654922B2 (en) * | 2016-05-13 | 2020-05-19 | Askgene Pharma Inc. | Angiopoietin 2, VEGF dual antagonists |
-
2019
- 2019-02-05 SG SG11202006712XA patent/SG11202006712XA/en unknown
- 2019-02-05 IL IL276383A patent/IL276383B2/en unknown
- 2019-02-05 EP EP19703978.7A patent/EP3749359A1/en active Pending
- 2019-02-05 JP JP2020536578A patent/JP7005772B2/en active Active
- 2019-02-05 AU AU2019219004A patent/AU2019219004A1/en active Pending
- 2019-02-05 CN CN201980011416.4A patent/CN111699004A/en active Pending
- 2019-02-05 KR KR1020207025450A patent/KR20200119274A/en not_active IP Right Cessation
- 2019-02-05 MX MX2020007527A patent/MX2020007527A/en unknown
- 2019-02-05 WO PCT/EP2019/052704 patent/WO2019154776A1/en unknown
- 2019-02-05 CA CA3088355A patent/CA3088355A1/en active Pending
- 2019-02-11 TW TW108104518A patent/TWI831764B/en active
-
2020
- 2020-08-05 US US16/985,477 patent/US20210139576A1/en not_active Abandoned
-
2022
- 2022-01-05 JP JP2022000341A patent/JP7273204B2/en active Active
-
2023
- 2023-02-09 US US18/166,996 patent/US20230416353A1/en active Pending
- 2023-04-27 JP JP2023073187A patent/JP2023099094A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| TW202000700A (en) | 2020-01-01 |
| WO2019154776A1 (en) | 2019-08-15 |
| TWI831764B (en) | 2024-02-11 |
| CA3088355A1 (en) | 2019-08-15 |
| JP7273204B2 (en) | 2023-05-12 |
| IL276383B1 (en) | 2023-09-01 |
| CN111699004A (en) | 2020-09-22 |
| JP2023099094A (en) | 2023-07-11 |
| KR20200119274A (en) | 2020-10-19 |
| IL276383A (en) | 2020-09-30 |
| EP3749359A1 (en) | 2020-12-16 |
| JP7005772B2 (en) | 2022-02-10 |
| MX2020007527A (en) | 2020-09-09 |
| JP2022046738A (en) | 2022-03-23 |
| AU2019219004A1 (en) | 2020-07-16 |
| IL276383B2 (en) | 2024-01-01 |
| US20230416353A1 (en) | 2023-12-28 |
| US20210139576A1 (en) | 2021-05-13 |
| JP2021506947A (en) | 2021-02-22 |
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