SG11202003094PA - Transglutaminase variants - Google Patents

Transglutaminase variants

Info

Publication number
SG11202003094PA
SG11202003094PA SG11202003094PA SG11202003094PA SG11202003094PA SG 11202003094P A SG11202003094P A SG 11202003094PA SG 11202003094P A SG11202003094P A SG 11202003094PA SG 11202003094P A SG11202003094P A SG 11202003094PA SG 11202003094P A SG11202003094P A SG 11202003094PA
Authority
SG
Singapore
Prior art keywords
transglutaminase variants
transglutaminase
variants
Prior art date
Application number
SG11202003094PA
Inventor
Jovana Nazor
Jie Yang
Goutami Banerjee
Xiyun Zhang
James Riggins
Erika Milczek
Jeffrey Moore
Original Assignee
Codexis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Codexis Inc filed Critical Codexis Inc
Publication of SG11202003094PA publication Critical patent/SG11202003094PA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/104—Aminoacyltransferases (2.3.2)
    • C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/02—Aminoacyltransferases (2.3.2)
    • C12Y203/02013—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
SG11202003094PA 2017-11-07 2018-11-02 Transglutaminase variants SG11202003094PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762582593P 2017-11-07 2017-11-07
PCT/US2018/059049 WO2019094301A1 (en) 2017-11-07 2018-11-02 Transglutaminase variants

Publications (1)

Publication Number Publication Date
SG11202003094PA true SG11202003094PA (en) 2020-05-28

Family

ID=66439313

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202003094PA SG11202003094PA (en) 2017-11-07 2018-11-02 Transglutaminase variants

Country Status (8)

Country Link
US (2) US11319531B2 (en)
EP (1) EP3706780A4 (en)
JP (1) JP2021502068A (en)
CN (1) CN111511389A (en)
CA (1) CA3080512A1 (en)
IL (1) IL274284A (en)
SG (1) SG11202003094PA (en)
WO (1) WO2019094301A1 (en)

Families Citing this family (10)

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EP3706780A4 (en) 2017-11-07 2021-12-22 Codexis, Inc. Transglutaminase variants
WO2021178001A1 (en) * 2020-03-05 2021-09-10 Curie Co. Inc. Methods for cell free protein expression of mature polypeptides derived from zymogens and proproteins
US20230125821A1 (en) * 2020-03-03 2023-04-27 Amano Enzyme Inc. Modified transglutaminase
JPWO2021256518A1 (en) * 2020-06-18 2021-12-23
MX2023002744A (en) * 2020-09-08 2023-04-03 Curie Co Inc Compositions and methods of use thereof.
CN116456832A (en) 2020-09-29 2023-07-18 味之素株式会社 Mutant glutamine transaminase
CN112553176B (en) * 2020-12-29 2022-04-29 江南大学 Glutamine transaminase with improved thermal stability
WO2022192529A1 (en) 2021-03-10 2022-09-15 Curie Co. Inc. Activation of zymogens by immobilized protease enzymes
WO2023058765A1 (en) * 2021-10-07 2023-04-13 天野エンザイム株式会社 Modified transglutaminase
WO2024054236A1 (en) 2022-09-09 2024-03-14 Curie Co. Inc. Immobilized proteases for activation of the zymogen form of transglutaminase

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Also Published As

Publication number Publication date
EP3706780A1 (en) 2020-09-16
JP2021502068A (en) 2021-01-28
US20200263150A1 (en) 2020-08-20
IL274284A (en) 2020-06-30
CN111511389A (en) 2020-08-07
CA3080512A1 (en) 2019-05-16
US20220220456A1 (en) 2022-07-14
EP3706780A4 (en) 2021-12-22
US11319531B2 (en) 2022-05-03
WO2019094301A1 (en) 2019-05-16

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