SG11202002300QA - Aztreonam derivatives and uses thereof - Google Patents

Aztreonam derivatives and uses thereof

Info

Publication number
SG11202002300QA
SG11202002300QA SG11202002300QA SG11202002300QA SG11202002300QA SG 11202002300Q A SG11202002300Q A SG 11202002300QA SG 11202002300Q A SG11202002300Q A SG 11202002300QA SG 11202002300Q A SG11202002300Q A SG 11202002300QA SG 11202002300Q A SG11202002300Q A SG 11202002300QA
Authority
SG
Singapore
Prior art keywords
aztreonam derivatives
aztreonam
derivatives
Prior art date
Application number
SG11202002300QA
Inventor
Eric Gordon
Matthew Duncton
John Freund
Original Assignee
Arixa Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arixa Pharmaceuticals Inc filed Critical Arixa Pharmaceuticals Inc
Publication of SG11202002300QA publication Critical patent/SG11202002300QA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/78Halides of sulfonic acids
    • C07C309/79Halides of sulfonic acids having halosulfonyl groups bound to acyclic carbon atoms
    • C07C309/82Halides of sulfonic acids having halosulfonyl groups bound to acyclic carbon atoms of a carbon skeleton substituted by singly-bound oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
SG11202002300QA 2017-10-02 2018-10-01 Aztreonam derivatives and uses thereof SG11202002300QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762566909P 2017-10-02 2017-10-02
PCT/US2018/053778 WO2019070595A1 (en) 2017-10-02 2018-10-01 Aztreonam derivatives and uses thereof

Publications (1)

Publication Number Publication Date
SG11202002300QA true SG11202002300QA (en) 2020-04-29

Family

ID=63963503

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202002300QA SG11202002300QA (en) 2017-10-02 2018-10-01 Aztreonam derivatives and uses thereof

Country Status (12)

Country Link
US (3) US10280161B2 (en)
EP (1) EP3676247B8 (en)
JP (1) JP6991345B2 (en)
KR (1) KR102455390B1 (en)
CN (1) CN111448182A (en)
AU (1) AU2018345321B2 (en)
BR (1) BR112020006594A2 (en)
CA (1) CA3077474A1 (en)
IL (1) IL273571A (en)
MX (1) MX2020004071A (en)
SG (1) SG11202002300QA (en)
WO (1) WO2019070595A1 (en)

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JP6991345B2 (en) * 2017-10-02 2022-01-12 アリクサ ファーマシューティカルズ、インコーポレイテッド Aztreonam derivatives and their use
EP3860999A1 (en) 2018-10-01 2021-08-11 Arixa Pharmaceuticals, Inc. Derivatives of relebactam and uses thereof
AU2020237440B2 (en) 2019-03-12 2022-10-20 Arixa Pharmaceuticals, Inc. Crystalline form of an avibactam derivative
US11565999B2 (en) 2019-04-25 2023-01-31 Arixa Pharmaceuticals, Inc. Methods of synthesizing aztreonam derivatives
US20210060033A1 (en) 2019-08-29 2021-03-04 Arixa Pharmaceuticals, Inc. Orally administered combinations of beta-lactam antibiotics and avibactam derivatives for treating bacterial infections
CN112047840A (en) * 2020-08-31 2020-12-08 山东药品食品职业学院 Synthesis method of 7-bromo-2, 2-dimethylheptanoic acid ethyl ester and product obtained by synthesis
CN112661716A (en) * 2020-12-31 2021-04-16 山东金城柯瑞化学有限公司 Preparation method of trityl aminothiazoly loximate
CN115448920A (en) * 2022-10-14 2022-12-09 广州楷石医药有限公司 Beta-lactamase inhibitor and application thereof

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Also Published As

Publication number Publication date
JP6991345B2 (en) 2022-01-12
CA3077474A1 (en) 2019-04-11
US10280161B2 (en) 2019-05-07
WO2019070595A1 (en) 2019-04-11
JP2020536122A (en) 2020-12-10
KR102455390B1 (en) 2022-10-17
BR112020006594A2 (en) 2020-12-15
CN111448182A (en) 2020-07-24
AU2018345321A1 (en) 2020-04-16
IL273571A (en) 2020-05-31
US20210009580A1 (en) 2021-01-14
EP3676247A1 (en) 2020-07-08
AU2018345321B2 (en) 2021-05-20
KR20200060490A (en) 2020-05-29
EP3676247B1 (en) 2023-03-08
MX2020004071A (en) 2020-07-28
US10815228B2 (en) 2020-10-27
US20190100516A1 (en) 2019-04-04
US20190211006A1 (en) 2019-07-11
EP3676247B8 (en) 2023-04-12

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