SG11201900361RA - Methods of treating prostate cancer - Google Patents

Methods of treating prostate cancer

Info

Publication number
SG11201900361RA
SG11201900361RA SG11201900361RA SG11201900361RA SG11201900361RA SG 11201900361R A SG11201900361R A SG 11201900361RA SG 11201900361R A SG11201900361R A SG 11201900361RA SG 11201900361R A SG11201900361R A SG 11201900361RA SG 11201900361R A SG11201900361R A SG 11201900361RA
Authority
SG
Singapore
Prior art keywords
international
applicant
johnson
road
pct
Prior art date
Application number
SG11201900361RA
Inventor
Rebecca Hawkins
Linda Snyder
Marco Gottardis
Douglas H Yamada
Original Assignee
Janssen Pharmaceutica Nv
Marco Gottardis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv, Marco Gottardis filed Critical Janssen Pharmaceutica Nv
Publication of SG11201900361RA publication Critical patent/SG11201900361RA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 1 Ill IOU 0 11101 010 11111 01 110 1 0 011101 0111 001 11111 010 1111 MEV OEM Organization International Bureau (10) International Publication Number (43) International Publication Date .....0\"\"\" WO 2018/023017 Al 01 February 2018 (01.02.2018) WIP0 I PCT (51) (21) (22) (25) Filing Language: (26) (30) (71) (72) (71) — (72) International Patent Classification: DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, A61K 31/454 (2006.01) A61P 35/00 (2006.01) HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, International Application Number: KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, PCT/US2017/044413 MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, International Filing Date: SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, 28 July 2017 (28.07.2017) TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. English (84) Designated States (unless otherwise indicated, for every Publication Language: English kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, Priority Data: UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, 62/368,466 29 July 2016 (29.07.2016) US TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, 62/369,239 01 August 2016 (01.08.2016) US EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, Applicant: JANSSEN PHARMACEUTICA NV TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, [BE/BE]; Turnhoutseweg 30, B-2340 Beerse (BE). KM, ML, MR, NE, SN, TD, TG). Inventor; and Applicant: GOTTARDIS, Marco [US/US]; 9 Harris Declarations under Rule 4.17: Road, Princeton, New Jersey 08540 (US). — as to applicant's entitlement to apply for and be granted a patent (Rule 4. 17(ii)) Inventors: HAWKINS, Rebecca; 1400 McKean Road, — as to the applicant's entitlement to claim the priority of the Spring House, 19477 (PA). SNYDER, Linda; 1400 McK- earlier application (Rule 4 . 17 (iii)) can Road, Spring House, Pennsylvania 19477 (US). YA- MADA, Douglas H.; 1400 McKean Road, Spring House, Published: Pennsylvania 19477 (US). — with international search report (Art. 21(3)) Agent: SHIRTZ, Joseph F. et al.; Johnson & Johnson, One Johnson & Johnson Plaza, New Brunswick, New Jer- sey 08933 (US). Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, — = (74) = (81) = = = Title: METHODS OF TREATING 100- 80- o c 60- ..m Tb 40- • - = c ._ 'e,.. ' 20 - 0 - 20 . 4 PROSTATE CANCER = (54) = = = = - • -A- C4-2B -A- LnCaP • = = • • • ...vir ...•- -yr- LnCaP AR.TB -e- VCaP -N- 22Rv 1 — = 1-1 IN 1-1 O M N 0 --.... 00 1-1 0 N (57) 0 Figure 1. : Disclosed are methods -2 . . . . . -1 0 1 2 3 log [niraparib], All Niraparib inhibits the growth of human prostate tumor cell lines in vitro. of treating prostate cancer by administering niraparib to a subject in need thereof.
SG11201900361RA 2016-07-29 2017-07-28 Methods of treating prostate cancer SG11201900361RA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662368466P 2016-07-29 2016-07-29
US201662369239P 2016-08-01 2016-08-01
PCT/US2017/044413 WO2018023017A1 (en) 2016-07-29 2017-07-28 Methods of treating prostate cancer

Publications (1)

Publication Number Publication Date
SG11201900361RA true SG11201900361RA (en) 2019-02-27

Family

ID=59649991

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201900361RA SG11201900361RA (en) 2016-07-29 2017-07-28 Methods of treating prostate cancer

Country Status (20)

Country Link
US (8) US20180028521A1 (en)
EP (1) EP3490560A1 (en)
JP (2) JP2019522032A (en)
KR (1) KR20190033599A (en)
CN (1) CN109640991A (en)
AU (2) AU2017302660B2 (en)
BR (1) BR112019001398A2 (en)
CA (1) CA3031705A1 (en)
CO (1) CO2019000753A2 (en)
DO (1) DOP2019000019A (en)
IL (1) IL264443A (en)
MA (1) MA45780A (en)
MX (1) MX2019001224A (en)
NI (1) NI201900009A (en)
PE (1) PE20190403A1 (en)
PH (1) PH12019500135A1 (en)
SG (1) SG11201900361RA (en)
SV (1) SV2019005822A (en)
UA (1) UA124972C2 (en)
WO (1) WO2018023017A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10806720B2 (en) 2015-04-21 2020-10-20 University Of Tennessee Research Foundation Selective androgen receptor degrader (SARD) ligands and methods of use thereof
US10865184B2 (en) 2015-04-21 2020-12-15 University Of Tennessee Research Foundation Selective androgen receptor degrader (SARD) ligands and methods of use thereof
US10093613B2 (en) 2015-04-21 2018-10-09 Gtx, Inc. Selective androgen receptor degrader (SARD) ligands and methods of use thereof
JP2019522032A (en) 2016-07-29 2019-08-08 ヤンセン ファーマシューティカ エヌ.ベー. How to treat prostate cancer
CN111801117A (en) * 2017-12-27 2020-10-20 特沙诺有限公司 Methods of treating cancer
JP7456942B2 (en) * 2018-05-16 2024-03-27 オンクターナル セラピューティクス,インコーポレイテッド Selective Androgen Receptor Degrader (SARD) Ligands and Methods of Use The Same
US20210340122A1 (en) * 2018-09-05 2021-11-04 University Of Tennessee Research Foundation Selective androgen receptor degrader (sard) ligands and methods of use thereof
WO2023001746A1 (en) * 2021-07-19 2023-01-26 Janssen Pharmaceutica Nv Treatment of metastatic castration-resistant prostate cancer with niraparib

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2109608B1 (en) 2007-01-10 2011-03-23 Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
CN106008460B (en) 2008-01-08 2022-08-12 默沙东公司 Pharmaceutically acceptable salts of 2- {4- [ (3S) -piperidin-3-yl ] phenyl } -2H-indazole-7-carboxamide
CA2723590C (en) 2008-05-07 2017-06-27 Cardioxyl Pharmaceuticals Inc. Novel nitroso compounds as nitroxyl donors and methods of use thereof
WO2012009475A1 (en) 2010-07-14 2012-01-19 Oregon Health & Science University Methods of treating cancer with inhibition of lysine-specific demethylase 1
WO2014089324A1 (en) 2012-12-07 2014-06-12 Calitor Sciences, Llc Substituted cyclic compounds and methods of use
EP3230472A4 (en) 2014-12-08 2018-06-13 Myriad Genetics, Inc. Methods and materials for predicting response to niraparib
JP2019522032A (en) * 2016-07-29 2019-08-08 ヤンセン ファーマシューティカ エヌ.ベー. How to treat prostate cancer
JOP20190244A1 (en) 2017-04-13 2019-10-13 Janssen Pharmaceutica Nv Combination therapy for prostate cancer

Also Published As

Publication number Publication date
PE20190403A1 (en) 2019-03-13
JP2022122920A (en) 2022-08-23
BR112019001398A2 (en) 2019-05-07
US20230149380A1 (en) 2023-05-18
US20190022079A1 (en) 2019-01-24
US20230078160A1 (en) 2023-03-16
CO2019000753A2 (en) 2019-02-08
US20220071980A1 (en) 2022-03-10
IL264443A (en) 2019-02-28
CN109640991A (en) 2019-04-16
MA45780A (en) 2019-06-05
DOP2019000019A (en) 2019-09-30
US20240000766A1 (en) 2024-01-04
NI201900009A (en) 2019-05-10
EP3490560A1 (en) 2019-06-05
MX2019001224A (en) 2019-06-03
US11207311B2 (en) 2021-12-28
PH12019500135A1 (en) 2019-10-28
UA124972C2 (en) 2021-12-22
KR20190033599A (en) 2019-03-29
SV2019005822A (en) 2019-03-28
US20230098047A1 (en) 2023-03-30
AU2023202813A1 (en) 2023-05-25
AU2017302660B2 (en) 2023-04-20
JP2019522032A (en) 2019-08-08
WO2018023017A1 (en) 2018-02-01
US20180028521A1 (en) 2018-02-01
US20220071979A1 (en) 2022-03-10
AU2017302660A1 (en) 2019-01-24
CA3031705A1 (en) 2018-02-01

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