SG11201706125QA - Anti-transthyretin antibodies - Google Patents
Anti-transthyretin antibodiesInfo
- Publication number
- SG11201706125QA SG11201706125QA SG11201706125QA SG11201706125QA SG11201706125QA SG 11201706125Q A SG11201706125Q A SG 11201706125QA SG 11201706125Q A SG11201706125Q A SG 11201706125QA SG 11201706125Q A SG11201706125Q A SG 11201706125QA SG 11201706125Q A SG11201706125Q A SG 11201706125QA
- Authority
- SG
- Singapore
- Prior art keywords
- transthyretin antibodies
- transthyretin
- antibodies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Psychiatry (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562109001P | 2015-01-28 | 2015-01-28 | |
US201562266557P | 2015-12-11 | 2015-12-11 | |
PCT/IB2016/050414 WO2016120809A1 (en) | 2015-01-28 | 2016-01-28 | Anti-transthyretin antibodies |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201706125QA true SG11201706125QA (en) | 2017-08-30 |
Family
ID=55361912
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201706125QA SG11201706125QA (en) | 2015-01-28 | 2016-01-28 | Anti-transthyretin antibodies |
Country Status (20)
Country | Link |
---|---|
US (1) | US20160257736A1 (en) |
EP (1) | EP3250594B1 (en) |
JP (2) | JP6875280B2 (en) |
KR (1) | KR102619359B1 (en) |
CN (1) | CN107428822B (en) |
AU (1) | AU2016210887B2 (en) |
BR (1) | BR112017016324A2 (en) |
CA (1) | CA2974911A1 (en) |
CO (1) | CO2017008469A2 (en) |
CU (1) | CU24532B1 (en) |
EA (1) | EA036048B1 (en) |
ES (1) | ES2905311T3 (en) |
MX (1) | MX2017009804A (en) |
MY (1) | MY193674A (en) |
PE (1) | PE20180200A1 (en) |
SA (1) | SA517381991B1 (en) |
SG (1) | SG11201706125QA (en) |
TW (2) | TWI781507B (en) |
WO (1) | WO2016120809A1 (en) |
ZA (1) | ZA201705662B (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10464999B2 (en) | 2015-01-28 | 2019-11-05 | Prothena Biosciences Limited | Anti-transthyretin antibodies |
US10633433B2 (en) | 2015-01-28 | 2020-04-28 | Prothena Biosciences Limited | Anti-transthyretin antibodies |
TWI781507B (en) * | 2015-01-28 | 2022-10-21 | 愛爾蘭商普羅佘納生物科技有限公司 | Anti-transthyretin antibodies |
US9879080B2 (en) | 2015-01-28 | 2018-01-30 | Prothena Biosciences Limited | Anti-transthyretin antibodies |
WO2018007924A2 (en) * | 2016-07-02 | 2018-01-11 | Prothena Biosciences Limited | Anti-transthyretin antibodies |
WO2018007922A2 (en) * | 2016-07-02 | 2018-01-11 | Prothena Biosciences Limited | Anti-transthyretin antibodies |
EP3478715A2 (en) * | 2016-07-02 | 2019-05-08 | Prothena Biosciences Limited | Anti-transthyretin antibodies |
CU20200021A7 (en) * | 2017-10-06 | 2021-01-12 | Prothena Biosciences Ltd | ANTI-TRANSTIRETIN ANTIBODIES |
PE20210042A1 (en) * | 2017-10-06 | 2021-01-08 | Prothena Biosciences Ltd | METHODS TO DETECT TRANSTIRETIN |
PE20211453A1 (en) | 2017-11-29 | 2021-08-05 | Prothena Biosciences Ltd | LYOPHILIZED FORMULATION OF A MONOCLONAL ANTIBODY AGAINST TRANSTIRETIN |
WO2020247452A1 (en) | 2019-06-04 | 2020-12-10 | Regeneron Pharmaceuticals, Inc. | Non-human animals comprising a humanized ttr locus with a beta-slip mutation and methods of use |
CN112816453B (en) * | 2021-02-09 | 2022-07-08 | 黑龙江大学 | Use of proteins for predicting drug performance |
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CH652145A5 (en) | 1982-01-22 | 1985-10-31 | Sandoz Ag | METHOD FOR IN VITRO PRODUCTION OF HYBRID OMEN WHAT human monoclonal antibodies GENERATE. |
US4634666A (en) | 1984-01-06 | 1987-01-06 | The Board Of Trustees Of The Leland Stanford Junior University | Human-murine hybridoma fusion partner |
US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
EP0279582A3 (en) | 1987-02-17 | 1989-10-18 | Pharming B.V. | Dna sequences to target proteins to the mammary gland for efficient secretion |
JP3101690B2 (en) | 1987-03-18 | 2000-10-23 | エス・ビィ・2・インコーポレイテッド | Modifications of or for denatured antibodies |
US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
US5633076A (en) | 1989-12-01 | 1997-05-27 | Pharming Bv | Method of producing a transgenic bovine or transgenic bovine embryo |
US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
EP0463151B1 (en) | 1990-01-12 | 1996-06-12 | Cell Genesys, Inc. | Generation of xenogeneic antibodies |
US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
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US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
US5814318A (en) | 1990-08-29 | 1998-09-29 | Genpharm International Inc. | Transgenic non-human animals for producing heterologous antibodies |
ES2108048T3 (en) | 1990-08-29 | 1997-12-16 | Genpharm Int | PRODUCTION AND USE OF LOWER TRANSGENIC ANIMALS CAPABLE OF PRODUCING HETEROLOGICAL ANTIBODIES. |
US5874299A (en) | 1990-08-29 | 1999-02-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
US5789650A (en) | 1990-08-29 | 1998-08-04 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
US5770429A (en) | 1990-08-29 | 1998-06-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
US5877397A (en) | 1990-08-29 | 1999-03-02 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
US5858657A (en) | 1992-05-15 | 1999-01-12 | Medical Research Council | Methods for producing members of specific binding pairs |
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EP0746609A4 (en) | 1991-12-17 | 1997-12-17 | Genpharm Int | Transgenic non-human animals capable of producing heterologous antibodies |
US5733743A (en) | 1992-03-24 | 1998-03-31 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
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US5827690A (en) | 1993-12-20 | 1998-10-27 | Genzyme Transgenics Corporatiion | Transgenic production of antibodies in milk |
US5914349A (en) | 1994-01-10 | 1999-06-22 | Teva Pharmaceutical Industries, Ltd. | Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives |
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WO2010030203A1 (en) * | 2008-09-09 | 2010-03-18 | Biocodex - Incubação De Empresas De Ciências Da Vida, S.A. | Monoclonal antibody to human amyloidogenic and modified forms of transthyretin and its use in the detection and treatment of fap and pathologies presenting modified ttr |
US9534048B2 (en) * | 2012-08-24 | 2017-01-03 | University Health Network | Antibodies to TTR and methods of use |
JP2016514091A (en) * | 2013-02-08 | 2016-05-19 | ミスフォールディング ダイアグノスティクス, インコーポレイテッド | Transthyretin antibodies and uses thereof |
TWI781507B (en) * | 2015-01-28 | 2022-10-21 | 愛爾蘭商普羅佘納生物科技有限公司 | Anti-transthyretin antibodies |
-
2016
- 2016-01-27 TW TW110100084A patent/TWI781507B/en active
- 2016-01-27 TW TW105102534A patent/TWI718121B/en active
- 2016-01-28 US US15/009,666 patent/US20160257736A1/en not_active Abandoned
- 2016-01-28 MX MX2017009804A patent/MX2017009804A/en unknown
- 2016-01-28 CA CA2974911A patent/CA2974911A1/en active Pending
- 2016-01-28 SG SG11201706125QA patent/SG11201706125QA/en unknown
- 2016-01-28 PE PE2017001286A patent/PE20180200A1/en unknown
- 2016-01-28 ES ES16704940T patent/ES2905311T3/en active Active
- 2016-01-28 AU AU2016210887A patent/AU2016210887B2/en active Active
- 2016-01-28 KR KR1020177023748A patent/KR102619359B1/en active IP Right Grant
- 2016-01-28 WO PCT/IB2016/050414 patent/WO2016120809A1/en active Application Filing
- 2016-01-28 CU CU2017000096A patent/CU24532B1/en unknown
- 2016-01-28 EP EP16704940.2A patent/EP3250594B1/en active Active
- 2016-01-28 CN CN201680015800.8A patent/CN107428822B/en active Active
- 2016-01-28 EA EA201791711A patent/EA036048B1/en unknown
- 2016-01-28 BR BR112017016324A patent/BR112017016324A2/en active Search and Examination
- 2016-01-28 MY MYPI2017702749A patent/MY193674A/en unknown
- 2016-01-28 JP JP2017540249A patent/JP6875280B2/en active Active
-
2017
- 2017-07-26 SA SA517381991A patent/SA517381991B1/en unknown
- 2017-08-21 ZA ZA2017/05662A patent/ZA201705662B/en unknown
- 2017-08-22 CO CONC2017/0008469A patent/CO2017008469A2/en unknown
-
2021
- 2021-04-22 JP JP2021072547A patent/JP7219928B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
CO2017008469A2 (en) | 2018-01-16 |
TW202118782A (en) | 2021-05-16 |
BR112017016324A2 (en) | 2018-03-27 |
AU2016210887A1 (en) | 2017-08-10 |
SA517381991B1 (en) | 2021-12-13 |
JP6875280B2 (en) | 2021-05-26 |
MY193674A (en) | 2022-10-24 |
JP2018509889A (en) | 2018-04-12 |
EP3250594A1 (en) | 2017-12-06 |
AU2016210887B2 (en) | 2021-11-04 |
CU24532B1 (en) | 2021-07-02 |
TWI781507B (en) | 2022-10-21 |
CN107428822B (en) | 2021-11-23 |
TW201636372A (en) | 2016-10-16 |
CN107428822A (en) | 2017-12-01 |
KR20170120607A (en) | 2017-10-31 |
EA036048B1 (en) | 2020-09-18 |
WO2016120809A1 (en) | 2016-08-04 |
EP3250594B1 (en) | 2021-11-17 |
CA2974911A1 (en) | 2016-08-04 |
ZA201705662B (en) | 2018-08-29 |
PE20180200A1 (en) | 2018-01-31 |
JP7219928B2 (en) | 2023-02-09 |
EA201791711A1 (en) | 2017-11-30 |
ES2905311T3 (en) | 2022-04-07 |
JP2021129562A (en) | 2021-09-09 |
US20160257736A1 (en) | 2016-09-08 |
TWI718121B (en) | 2021-02-11 |
CU20170096A7 (en) | 2018-03-13 |
MX2017009804A (en) | 2018-08-15 |
KR102619359B1 (en) | 2024-01-02 |
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