SG11201702978VA - Method for the enrichment of circulating tumor dna - Google Patents
Method for the enrichment of circulating tumor dnaInfo
- Publication number
- SG11201702978VA SG11201702978VA SG11201702978VA SG11201702978VA SG11201702978VA SG 11201702978V A SG11201702978V A SG 11201702978VA SG 11201702978V A SG11201702978V A SG 11201702978VA SG 11201702978V A SG11201702978V A SG 11201702978VA SG 11201702978V A SG11201702978V A SG 11201702978VA
- Authority
- SG
- Singapore
- Prior art keywords
- enrichment
- circulating tumor
- tumor dna
- dna
- circulating
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6875—Nucleoproteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
- G01N27/622—Ion mobility spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2560/00—Chemical aspects of mass spectrometric analysis of biological material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/70—Mechanisms involved in disease identification
- G01N2800/7023—(Hyper)proliferation
- G01N2800/7028—Cancer
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1419225.6A GB201419225D0 (en) | 2014-10-29 | 2014-10-29 | Method for the enrichment of circulating tumor DNA |
| GB201419299A GB201419299D0 (en) | 2014-10-30 | 2014-10-30 | Method for the enrichment of circulating tumour DNA |
| PCT/GB2015/053238 WO2016067029A1 (en) | 2014-10-29 | 2015-10-29 | Method for the enrichment of circulating tumor dna |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201702978VA true SG11201702978VA (en) | 2017-05-30 |
Family
ID=54427791
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201702978VA SG11201702978VA (en) | 2014-10-29 | 2015-10-29 | Method for the enrichment of circulating tumor dna |
| SG10201903822XA SG10201903822XA (en) | 2014-10-29 | 2015-10-29 | Method for the enrichment of circulating tumor dna |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201903822XA SG10201903822XA (en) | 2014-10-29 | 2015-10-29 | Method for the enrichment of circulating tumor dna |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20180024141A1 (en) |
| EP (2) | EP3213084B2 (en) |
| JP (1) | JP6721599B2 (en) |
| CN (2) | CN107209190B (en) |
| AU (1) | AU2015340378B2 (en) |
| CA (1) | CA2965752C (en) |
| DK (1) | DK3213084T4 (en) |
| ES (1) | ES2839973T3 (en) |
| HK (1) | HK1243764A1 (en) |
| IL (1) | IL251896A0 (en) |
| NZ (1) | NZ731116A (en) |
| PL (1) | PL3213084T3 (en) |
| SG (2) | SG11201702978VA (en) |
| WO (1) | WO2016067029A1 (en) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2930180T3 (en) | 2012-03-02 | 2022-12-07 | Sequenom Inc | Methods for enriching for cancer nucleic acid from a biological sample |
| EP3597774A1 (en) | 2013-03-13 | 2020-01-22 | Sequenom, Inc. | Primers for dna methylation analysis |
| WO2015138774A1 (en) | 2014-03-13 | 2015-09-17 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| CN106544341A (en) * | 2017-01-17 | 2017-03-29 | 上海亿康医学检验所有限公司 | The method of the ctDNA in efficient detection sample |
| US11724015B2 (en) | 2017-09-18 | 2023-08-15 | Santersus Ag | Method and device for purification of blood from circulating cell free DNA |
| CN109932224A (en) * | 2017-12-18 | 2019-06-25 | 中国科学院大连化学物理研究所 | A method of Circulating tumor DNA is extracted in enrichment |
| CN112119166A (en) * | 2018-03-13 | 2020-12-22 | 耶路撒冷希伯来大学伊萨姆研发有限公司 | Diagnostic use of cell-free DNA chromatin immunoprecipitation |
| GB201818963D0 (en) | 2018-11-21 | 2019-01-09 | Belgian Volition Sprl | Methof for the detection of prostate cancer |
| GB201818965D0 (en) | 2018-11-21 | 2019-01-09 | Belgian Volition Sprl | Method for the detection of colorectal cancer |
| CN109841265B (en) * | 2019-02-22 | 2021-09-21 | 清华大学 | Method and system for determining tissue source of plasma free nucleic acid molecules by using fragmentation mode and application |
| GB201906201D0 (en) | 2019-05-02 | 2019-06-19 | Belgian Voltion Sprl | Method for the detection of protate cancer |
| GB201906199D0 (en) | 2019-05-02 | 2019-06-19 | Belgian Volition Sprl | Method for the detection of cancer |
| US20240052334A1 (en) * | 2019-10-04 | 2024-02-15 | Santersus Ag | Method for isolating and analyzing cell free dna |
| JP7349104B2 (en) * | 2019-11-13 | 2023-09-22 | 株式会社島津製作所 | How to detect verotoxin |
| JP2023503379A (en) | 2019-12-02 | 2023-01-27 | ベルジアン ボリション エスアールエル | Use of extracellular free nucleosomes as biomarkers |
| GB202117799D0 (en) | 2021-12-09 | 2022-01-26 | Belgian Volition Srl | Method for the detection of blood cancer |
| WO2023122623A1 (en) * | 2021-12-21 | 2023-06-29 | Guardant Health, Inc. | Methods and systems for combinatorial chromatin-ip sequencing |
| WO2023170298A1 (en) | 2022-03-11 | 2023-09-14 | Belgian Volition Srl | Differential diagnosis method |
| WO2024042210A1 (en) * | 2022-08-25 | 2024-02-29 | Belgian Volition Srl | Method for measuring cell free chromatin |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0319376D0 (en) * | 2003-08-18 | 2003-09-17 | Chroma Therapeutics Ltd | Histone modification detection |
| US20060115482A1 (en) * | 2004-04-27 | 2006-06-01 | The Regents Of The University Of California | Modifications of histone proteins as indicators of cell proliferation and differentiation |
| US20070243549A1 (en) * | 2006-04-12 | 2007-10-18 | Biocept, Inc. | Enrichment of circulating fetal dna |
| EP2062912A1 (en) * | 2007-11-26 | 2009-05-27 | Koninklijke Philips Electronics N.V. | Selective enrichment of post-translationally modified proteins and/or peptides |
| US20100240054A1 (en) * | 2008-09-22 | 2010-09-23 | Biocept, Inc. | Identification and isolation of fetal cells and nucleic acid |
| EP2419737A4 (en) * | 2009-04-14 | 2013-02-13 | Univ California | Histone modification patterns for clinical diagnosis and prognosis of cancer |
| WO2013010181A2 (en) * | 2011-07-14 | 2013-01-17 | University Of Massachusetts | Methods of diagnosing cancer using epigenetic biomarkers |
| GB201115095D0 (en) † | 2011-09-01 | 2011-10-19 | Singapore Volition Pte Ltd | Method for detecting nucleosomes containing nucleotides |
| GB201115098D0 (en) * | 2011-09-01 | 2011-10-19 | Belgian Volition Sa | Method for detecting nucleosomes containing histone variants |
| CA2854255C (en) * | 2011-11-21 | 2022-01-25 | The Royal Institution For The Advancement Of Learning / Mcgill University | Mutations of histone proteins associated with proliferative disorders |
| JP6263474B2 (en) | 2011-12-07 | 2018-01-17 | シンガポール ボリション ピーティーイー リミテッド | Nucleosome adduct detection method |
| ES2930180T3 (en) † | 2012-03-02 | 2022-12-07 | Sequenom Inc | Methods for enriching for cancer nucleic acid from a biological sample |
| US9388213B2 (en) * | 2012-09-10 | 2016-07-12 | The Rockefeller University | Polycomb repressive complex 2 (PRC2) inhibitors and uses thereof |
-
2015
- 2015-10-29 SG SG11201702978VA patent/SG11201702978VA/en unknown
- 2015-10-29 AU AU2015340378A patent/AU2015340378B2/en active Active
- 2015-10-29 CA CA2965752A patent/CA2965752C/en active Active
- 2015-10-29 SG SG10201903822XA patent/SG10201903822XA/en unknown
- 2015-10-29 EP EP15790214.9A patent/EP3213084B2/en active Active
- 2015-10-29 PL PL15790214T patent/PL3213084T3/en unknown
- 2015-10-29 DK DK15790214.9T patent/DK3213084T4/en active
- 2015-10-29 ES ES15790214T patent/ES2839973T3/en active Active
- 2015-10-29 EP EP20203154.8A patent/EP3809140A1/en active Pending
- 2015-10-29 JP JP2017542357A patent/JP6721599B2/en active Active
- 2015-10-29 CN CN201580058989.4A patent/CN107209190B/en active Active
- 2015-10-29 CN CN202010018617.1A patent/CN111505305B/en active Active
- 2015-10-29 US US15/523,280 patent/US20180024141A1/en not_active Abandoned
- 2015-10-29 NZ NZ731116A patent/NZ731116A/en unknown
- 2015-10-29 WO PCT/GB2015/053238 patent/WO2016067029A1/en active Application Filing
-
2017
- 2017-04-25 IL IL251896A patent/IL251896A0/en active IP Right Grant
-
2018
- 2018-03-05 HK HK18103101.0A patent/HK1243764A1/en active IP Right Maintenance
-
2022
- 2022-06-07 US US17/834,701 patent/US20220334128A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| SG10201903822XA (en) | 2019-05-30 |
| CA2965752C (en) | 2024-04-02 |
| NZ731116A (en) | 2024-03-22 |
| JP6721599B2 (en) | 2020-07-15 |
| EP3213084B1 (en) | 2020-11-25 |
| WO2016067029A1 (en) | 2016-05-06 |
| CA2965752A1 (en) | 2016-05-06 |
| HK1243764A1 (en) | 2018-07-20 |
| US20180024141A1 (en) | 2018-01-25 |
| EP3213084A1 (en) | 2017-09-06 |
| CN111505305B (en) | 2023-10-17 |
| JP2017534300A (en) | 2017-11-24 |
| EP3213084B2 (en) | 2023-12-13 |
| EP3809140A1 (en) | 2021-04-21 |
| IL251896A0 (en) | 2017-06-29 |
| AU2015340378A1 (en) | 2017-05-11 |
| CN107209190B (en) | 2021-07-16 |
| AU2015340378B2 (en) | 2021-08-12 |
| ES2839973T3 (en) | 2021-07-06 |
| DK3213084T4 (en) | 2024-03-18 |
| DK3213084T3 (en) | 2021-01-18 |
| PL3213084T3 (en) | 2021-07-26 |
| CN111505305A (en) | 2020-08-07 |
| CN107209190A (en) | 2017-09-26 |
| US20220334128A1 (en) | 2022-10-20 |
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