SG11201602879UA - Exosome recovery methods with low molecular weight organic zwitterions - Google Patents
Exosome recovery methods with low molecular weight organic zwitterionsInfo
- Publication number
- SG11201602879UA SG11201602879UA SG11201602879UA SG11201602879UA SG11201602879UA SG 11201602879U A SG11201602879U A SG 11201602879UA SG 11201602879U A SG11201602879U A SG 11201602879UA SG 11201602879U A SG11201602879U A SG 11201602879UA SG 11201602879U A SG11201602879U A SG 11201602879UA
- Authority
- SG
- Singapore
- Prior art keywords
- molecular weight
- low molecular
- weight organic
- recovery methods
- organic zwitterions
- Prior art date
Links
- 210000001808 exosome Anatomy 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000011084 recovery Methods 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5076—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving cell organelles, e.g. Golgi complex, endoplasmic reticulum
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0081—Purging biological preparations of unwanted cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
- B01D15/361—Ion-exchange
- B01D15/364—Amphoteric or zwitterionic ion-exchanger
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D35/00—Filtering devices having features not specifically covered by groups B01D24/00 - B01D33/00, or for applications not specifically covered by groups B01D24/00 - B01D33/00; Auxiliary devices for filtration; Filter housing constructions
- B01D35/02—Filters adapted for location in special places, e.g. pipe-lines, pumps, stop-cocks
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B1/00—Centrifuges with rotary bowls provided with solid jackets for separating predominantly liquid mixtures with or without solid particles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Toxicology (AREA)
- General Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361895338P | 2013-10-24 | 2013-10-24 | |
| PCT/SG2014/000485 WO2015060784A1 (en) | 2013-10-24 | 2014-10-15 | Exosome recovery methods with low molecular weight organic zwitterions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201602879UA true SG11201602879UA (en) | 2016-05-30 |
Family
ID=52993252
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201602879UA SG11201602879UA (en) | 2013-10-24 | 2014-10-15 | Exosome recovery methods with low molecular weight organic zwitterions |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9927427B2 (en) |
| EP (1) | EP3060911A4 (en) |
| JP (1) | JP6510508B2 (en) |
| KR (1) | KR20160075692A (en) |
| CN (1) | CN105849554B (en) |
| SG (1) | SG11201602879UA (en) |
| WO (1) | WO2015060784A1 (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2344202B1 (en) | 2008-09-08 | 2020-03-11 | Children's Medical Center Corporation | Mucosal delivery of therapeutic molecules, proteins, or particles coupled to ceramide lipids |
| WO2017117585A1 (en) * | 2015-12-30 | 2017-07-06 | The Regents Of The University Of California | Methods for enhanced production and isolation of cell-derived vesicles |
| WO2017175736A1 (en) * | 2016-04-04 | 2017-10-12 | 国立研究開発法人産業技術総合研究所 | Method for preparing membrane vesicles suitable for biophysical analysis |
| KR101895916B1 (en) * | 2017-08-11 | 2018-09-07 | 주식회사 엑소코바이오 | A method to prepare an exosome and/or extracellular vesicle and a composition comprising it |
| WO2019083201A2 (en) * | 2017-10-24 | 2019-05-02 | 주식회사 엑소코바이오 | Use of composition comprising adipose stem cell-derived exosome as effective ingredient in improving renal function |
| JP2021501161A (en) | 2017-10-27 | 2021-01-14 | ザ チルドレンズ メディカル センター コーポレーション | Short-chain ceramide-based lipids and their use |
| WO2019152970A1 (en) | 2018-02-05 | 2019-08-08 | Clemson University Research Foundation | Channeled fibers in separation of biologically active nanoparticles |
| JP2021521199A (en) | 2018-04-12 | 2021-08-26 | チルドレンズ メディカル センター コーポレーションＣｈｉｌｄｒｅｎ’Ｓ Ｍｅｄｉｃａｌ Ｃｅｎｔｅｒ Ｃｏｒｐｏｒａｔｉｏｎ | Ceramide-like lipid-based delivery vehicle and its use |
| CN109609458A (en) * | 2018-12-29 | 2019-04-12 | 暨南大学 | A kind of method of low speed ultrafiltration centrifugation conjugated polymer sedimentation separation excretion body |
| US20210197162A1 (en) * | 2019-12-30 | 2021-07-01 | Industrial Technology Research Institute | Extracellular vesicle separation method, colloidal particle and preparation method thereof |
| WO2021221368A1 (en) * | 2020-04-28 | 2021-11-04 | 주식회사 엠디뮨 | Method for filtration of cell-derived vesicle |
| CN111621471B (en) * | 2020-06-12 | 2022-03-11 | 成都世联康健生物科技有限公司 | Extraction method and application of soft tissue extracellular vesicles |
| CN114323863B (en) * | 2021-12-31 | 2023-12-22 | 吉林大学 | Preparation method and application of exosome array capture probe |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6812023B1 (en) | 2000-04-27 | 2004-11-02 | Anosys, Inc. | Methods of producing membrane vesicles |
| US20120244212A1 (en) * | 2004-11-07 | 2012-09-27 | Frederick Timothy Guilford | Enhanced method and composition for the treatment of hiv+ tuberculosis patients with anti-retroviral drugs and liposomal encapsulation for delivery of reduced glutathione |
| US10545149B2 (en) * | 2008-10-06 | 2020-01-28 | Morehouse School Of Medicine | Detection of HIV-related proteins in urine |
| WO2011017137A2 (en) * | 2009-08-03 | 2011-02-10 | Alnylam Pharmaceuticals, Inc. | Methods and compositions for treating insects |
| WO2011062244A1 (en) * | 2009-11-18 | 2011-05-26 | Kuroda Masahiko | Carrier, method for producing same, and applications of same |
| WO2012126531A1 (en) * | 2011-03-24 | 2012-09-27 | Cavadis B.V. | Method for diagnosing acute coronary syndrome (acs) |
| SG10201603931TA (en) * | 2011-06-08 | 2016-07-28 | Agency Science Tech & Res | Purification Of Biological Products By Constrained Cohydration Chromatography |
| CN102349998A (en) * | 2011-10-20 | 2012-02-15 | 天津大学 | Hydrophobic anticancer medicinal preparation on basis of exosome |
| US9777042B2 (en) * | 2011-12-15 | 2017-10-03 | Morehouse School Of Medicine | Method of purifying HIV/SIV Nef from exosomal fusion proteins |
| KR101933621B1 (en) * | 2012-09-28 | 2018-12-28 | 삼성전자주식회사 | Compositions and kits for isolating a vesicle, and methods for isolating the vesicle using the same |
| CN103197066B (en) * | 2013-03-07 | 2015-12-23 | 美国纳米材料创新有限公司 | A kind of immunoliposome biochip, its preparation method and the application in biological detection thereof |
-
2014
- 2014-10-15 US US15/031,660 patent/US9927427B2/en not_active Expired - Fee Related
- 2014-10-15 EP EP14855837.2A patent/EP3060911A4/en active Pending
- 2014-10-15 SG SG11201602879UA patent/SG11201602879UA/en unknown
- 2014-10-15 KR KR1020167013699A patent/KR20160075692A/en not_active Application Discontinuation
- 2014-10-15 JP JP2016523215A patent/JP6510508B2/en not_active Expired - Fee Related
- 2014-10-15 CN CN201480057767.6A patent/CN105849554B/en not_active Expired - Fee Related
- 2014-10-15 WO PCT/SG2014/000485 patent/WO2015060784A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| EP3060911A4 (en) | 2017-06-21 |
| CN105849554A (en) | 2016-08-10 |
| EP3060911A1 (en) | 2016-08-31 |
| JP2017505753A (en) | 2017-02-23 |
| KR20160075692A (en) | 2016-06-29 |
| US20160266097A1 (en) | 2016-09-15 |
| JP6510508B2 (en) | 2019-05-08 |
| US9927427B2 (en) | 2018-03-27 |
| WO2015060784A1 (en) | 2015-04-30 |
| CN105849554B (en) | 2019-02-15 |
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