SG11201510505VA - Use of semaphorin-4d inhibitory molecules in combination with an immune modulating therapy to inhibit tumor growth and metastases - Google Patents

Use of semaphorin-4d inhibitory molecules in combination with an immune modulating therapy to inhibit tumor growth and metastases

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Publication number
SG11201510505VA
SG11201510505VA SG11201510505VA SG11201510505VA SG11201510505VA SG 11201510505V A SG11201510505V A SG 11201510505VA SG 11201510505V A SG11201510505V A SG 11201510505VA SG 11201510505V A SG11201510505V A SG 11201510505VA SG 11201510505V A SG11201510505V A SG 11201510505VA
Authority
SG
Singapore
Prior art keywords
semaphorin
metastases
combination
tumor growth
inhibit tumor
Prior art date
Application number
SG11201510505VA
Inventor
Elizabeth E Evans
Ernest S Smith
Maurice Zauderer
Original Assignee
Vaccinex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vaccinex Inc filed Critical Vaccinex Inc
Publication of SG11201510505VA publication Critical patent/SG11201510505VA/en

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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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    • C12N2501/20—Cytokines; Chemokines
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    • G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations

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SG11201510505VA 2013-06-25 2014-06-20 Use of semaphorin-4d inhibitory molecules in combination with an immune modulating therapy to inhibit tumor growth and metastases SG11201510505VA (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361839170P 2013-06-25 2013-06-25
US201361874241P 2013-09-05 2013-09-05
US201361884771P 2013-09-30 2013-09-30
US201361907845P 2013-11-22 2013-11-22
PCT/US2014/043466 WO2014209802A1 (en) 2013-06-25 2014-06-20 Use of semaphorin-4d inhibitory molecules in combination with an immune modulating therapy to inhibit tumor growth and metastases

Publications (1)

Publication Number Publication Date
SG11201510505VA true SG11201510505VA (en) 2016-01-28

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SG11201510505VA SG11201510505VA (en) 2013-06-25 2014-06-20 Use of semaphorin-4d inhibitory molecules in combination with an immune modulating therapy to inhibit tumor growth and metastases
SG10201902380SA SG10201902380SA (en) 2013-06-25 2014-06-20 Use of semaphorin-4d inhibitory molecules in combination with an immune modulating therapy to inhibit tumor growth and metastases

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SG10201902380SA SG10201902380SA (en) 2013-06-25 2014-06-20 Use of semaphorin-4d inhibitory molecules in combination with an immune modulating therapy to inhibit tumor growth and metastases

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US (5) US9828435B2 (en)
EP (2) EP3656392A1 (en)
JP (3) JP6611709B2 (en)
KR (2) KR20210104166A (en)
CN (1) CN105492016A (en)
AU (2) AU2014302812B2 (en)
BR (1) BR112015032690B1 (en)
CA (2) CA2916245C (en)
DK (1) DK3013350T3 (en)
EA (1) EA036591B1 (en)
ES (1) ES2782834T3 (en)
IL (1) IL243301B (en)
MX (1) MX2015017485A (en)
NZ (1) NZ631015A (en)
PL (1) PL3013350T3 (en)
PT (1) PT3013350T (en)
SG (2) SG11201510505VA (en)
WO (1) WO2014209802A1 (en)

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