SG11201407402TA - Carbazole-containing sulfonamides as cryptochrome modulators - Google Patents
Carbazole-containing sulfonamides as cryptochrome modulatorsInfo
- Publication number
- SG11201407402TA SG11201407402TA SG11201407402TA SG11201407402TA SG11201407402TA SG 11201407402T A SG11201407402T A SG 11201407402TA SG 11201407402T A SG11201407402T A SG 11201407402TA SG 11201407402T A SG11201407402T A SG 11201407402TA SG 11201407402T A SG11201407402T A SG 11201407402TA
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- SG
- Singapore
- Prior art keywords
- international
- carbazole
- suite
- pct
- unless
- Prior art date
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Abstract
(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 14 November 2013 (14.11.2013) WIPOIPCT (10) International Publication Number WO 2013/170186 A1 (51) International Patent Classification: C07D 403/12 C07D 405/14 C07D 401/06 C07D 401/12 C07D 403/06 C07D 405/12 C07D 409/12 C07D 413/12 (2006.01) C07D417/06 (2006.01) (2006.01) C07D 493/08 (2006.01) (2006.01) C07D 209/86 (2006.01) (2006.01) C07D 209/88 ( 2006.01) (2006.01) A61K31/403 (2006.01) (2006.01) A61P 3/00 (2006.01) (2006.01) A61P 25/00 (2006.01) (2006.01) (21) International Application Number: (22) International Filing Date: (25) Filing Language: (26) Publication Language: PCT/US2013/040604 10 May 2013 (10.05.2013) English English (30) Priority Data: 61/645,918 61/778,176 11 May 2012 (11.05.2012) US 12 March 2013 (12.03.2013) US (71) Applicant: RESET THERAPEUTICS, INC. [US/US]; 863a Mitten Road, Suite 100c, Burlingame, CA 94010 (US). (72) Inventors: BERSOT, Ross; C/o Bay City Capital, 750 Battery Street, Suite 400, San Francisco, CA 94111 (US). HUMPHRIES, Paul; C/o Bay City Capital, 750 Battery Street, Suite 400, San Francisco, CA 94111 (US). (74) Agents: ELRIFI, Ivor, R. et al.; Mintz Levin Cohn Ferris Glovsky And Popeo, P.c., Chrysler Center, 666 Third Av enue, New York, NY 10017 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) — before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) (54) Title: CARBAZOLE-CONTAINING SULFONAMIDES AS CRYPTOCHROME MODULATORS 00 T-H o l> G' \ \" 3 H^TN' R4 0H/S A <r 0 B-VC (R ) 2 b R( (i) i-H (57) Abstract: The subject matter herein is directed to carbazole-containing sulfonamide derivatives and pharmaceutically accept- O able salts or hydrates thereof of structural formula wherein I the variable Ri, R , 2 R3, R4, R5, R6, R7, A, B, C, D, E, F, G, H, a, and b CJ are accordingly described. Also provided are pharmaceutical compositions comprising the compounds of formula I to treat a Cry- Q mediated disease or disorder, such as diabetes, obesity, metabolic syndrome, Cushing's syndrome, and glaucoma.
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US201261645918P | 2012-05-11 | 2012-05-11 | |
US201361778176P | 2013-03-12 | 2013-03-12 | |
PCT/US2013/040604 WO2013170186A1 (en) | 2012-05-11 | 2013-05-10 | Carbazole-containing sulfonamides as cryptochrome modulators |
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US (3) | US9265772B2 (en) |
EP (1) | EP2855458B1 (en) |
JP (5) | JP6377054B2 (en) |
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CN (2) | CN107674071B (en) |
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AU (1) | AU2013259294B2 (en) |
CA (1) | CA2873214C (en) |
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- 2013-05-10 TW TW106124610A patent/TWI643845B/en active
- 2013-05-10 SG SG11201407402TA patent/SG11201407402TA/en unknown
- 2013-05-10 JP JP2015511772A patent/JP6377054B2/en active Active
- 2013-05-10 TW TW102116699A patent/TWI601714B/en active
- 2013-05-13 AR ARP130101653A patent/AR092319A1/en active IP Right Grant
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2014
- 2014-11-10 IL IL235602A patent/IL235602A0/en active IP Right Grant
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2016
- 2016-01-12 US US14/994,005 patent/US9775845B2/en active Active
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2017
- 2017-07-20 JP JP2017140820A patent/JP2017200946A/en not_active Withdrawn
- 2017-09-22 US US15/712,983 patent/US10383880B2/en active Active
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2018
- 2018-07-26 HK HK18109672.6A patent/HK1250232A1/en unknown
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2019
- 2019-01-31 JP JP2019015689A patent/JP2019077722A/en not_active Withdrawn
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2020
- 2020-09-24 JP JP2020159390A patent/JP2020203948A/en not_active Withdrawn
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2022
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