SG11201405990PA - Biocatalysts and methods for synthesizing derivatives of tryptamine and tryptamine analogs - Google Patents

Biocatalysts and methods for synthesizing derivatives of tryptamine and tryptamine analogs

Info

Publication number
SG11201405990PA
SG11201405990PA SG11201405990PA SG11201405990PA SG11201405990PA SG 11201405990P A SG11201405990P A SG 11201405990PA SG 11201405990P A SG11201405990P A SG 11201405990PA SG 11201405990P A SG11201405990P A SG 11201405990PA SG 11201405990P A SG11201405990P A SG 11201405990PA
Authority
SG
Singapore
Prior art keywords
tryptamine
biocatalysts
methods
analogs
synthesizing derivatives
Prior art date
Application number
SG11201405990PA
Inventor
Jovana Nazor
Derek Smith
Michael A Crowe
Shiwei Song
Steven J Collier
Original Assignee
Codexis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Codexis Inc filed Critical Codexis Inc
Publication of SG11201405990PA publication Critical patent/SG11201405990PA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y206/00—Transferases transferring nitrogenous groups (2.6)
    • C12Y206/01—Transaminases (2.6.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y206/00—Transferases transferring nitrogenous groups (2.6)
    • C12Y206/01—Transaminases (2.6.1)
    • C12Y206/01018—Beta-alanine-pyruvate transaminase (2.6.1.18)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG11201405990PA 2012-03-23 2013-03-22 Biocatalysts and methods for synthesizing derivatives of tryptamine and tryptamine analogs SG11201405990PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261614666P 2012-03-23 2012-03-23
PCT/US2013/033456 WO2013142770A1 (en) 2012-03-23 2013-03-22 Biocatalysts and methods for synthesizing derivatives of tryptamine and tryptamine analogs

Publications (1)

Publication Number Publication Date
SG11201405990PA true SG11201405990PA (en) 2014-11-27

Family

ID=49223365

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201405990PA SG11201405990PA (en) 2012-03-23 2013-03-22 Biocatalysts and methods for synthesizing derivatives of tryptamine and tryptamine analogs

Country Status (7)

Country Link
US (6) US9139821B2 (en)
EP (1) EP2828385B1 (en)
CN (1) CN104508126B (en)
DK (1) DK2828385T3 (en)
HU (1) HUE036985T2 (en)
SG (1) SG11201405990PA (en)
WO (1) WO2013142770A1 (en)

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* Cited by examiner, † Cited by third party
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HUE036985T2 (en) 2012-03-23 2018-08-28 Codexis Inc Biocatalysts and methods for synthesizing derivatives of tryptamine and tryptamine analogs
HUE046421T2 (en) * 2012-03-23 2020-02-28 Novartis Ag Chemical process for preparing spiroindolones and intermediates thereof
EP2935572B1 (en) 2012-12-21 2020-09-30 Codexis, Inc. Engineered biocatalysts and methods for synthesizing chiral amines
CN118005631A (en) 2014-12-18 2024-05-10 豪夫迈·罗氏有限公司 Tetrahydro-pyrido [3,4-b ] indole estrogen receptor modulators and uses thereof
CA3064574A1 (en) * 2017-06-14 2018-12-20 Codexis, Inc. Engineered transaminase polypeptides for industrial biocatalysis
HUE064542T2 (en) 2018-06-21 2024-03-28 Hoffmann La Roche Solid forms of the tartrate salt of 3-((1r,3r)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3-yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydro-2h-pyrido[3,4-b]indol-2-yl)-2,2-difluoropropan-1-ol, process for their preparation and methods of their use in treating cancers
JP2023521772A (en) * 2020-04-10 2023-05-25 コデクシス， インコーポレイテッド Engineered transaminase polypeptide
CA3177454A1 (en) 2020-05-19 2021-11-25 Cybin Irl Limited Deuterated tryptamine derivatives and methods of use
EP4217502A1 (en) * 2020-09-28 2023-08-02 Codexis, Inc. Engineered biocatalysts and methods for synthesizing chiral amines
CN112346465B (en) * 2020-11-27 2022-09-02 哈尔滨工程大学 IALOS guide law-based adaptive fuzzy control method for under-actuated unmanned ship
AU2022281358A1 (en) * 2021-05-25 2023-11-23 Atai Therapeutics, Inc. New n,n-dimethyltryptamine salts and crystalline salt forms

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EP2935572B1 (en) * 2012-12-21 2020-09-30 Codexis, Inc. Engineered biocatalysts and methods for synthesizing chiral amines

Also Published As

Publication number Publication date
US20150072383A1 (en) 2015-03-12
US11098291B2 (en) 2021-08-24
US9708588B2 (en) 2017-07-18
US9139821B2 (en) 2015-09-22
CN104508126B (en) 2017-06-30
US20150344854A1 (en) 2015-12-03
EP2828385B1 (en) 2018-02-07
US10544402B2 (en) 2020-01-28
WO2013142770A1 (en) 2013-09-26
HUE036985T2 (en) 2018-08-28
EP2828385A4 (en) 2015-09-16
DK2828385T3 (en) 2018-03-12
US20200123512A1 (en) 2020-04-23
US20160289649A1 (en) 2016-10-06
US20210348139A1 (en) 2021-11-11
US20170283781A1 (en) 2017-10-05
CN104508126A (en) 2015-04-08
US9388395B2 (en) 2016-07-12
EP2828385A1 (en) 2015-01-28

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