SG11201401342VA - 5,7-substituted-imidazo[1,2-c]pyrimidines - Google Patents

5,7-substituted-imidazo[1,2-c]pyrimidines

Info

Publication number
SG11201401342VA
SG11201401342VA SG11201401342VA SG11201401342VA SG11201401342VA SG 11201401342V A SG11201401342V A SG 11201401342VA SG 11201401342V A SG11201401342V A SG 11201401342VA SG 11201401342V A SG11201401342V A SG 11201401342VA SG 11201401342V A SG11201401342V A SG 11201401342VA
Authority
SG
Singapore
Prior art keywords
pyrimidines
imidazo
substituted
Prior art date
Application number
SG11201401342VA
Inventor
Mark Laurence Boys
Laurence E Burgess
C Todd Eary
Robert Groneberg
Bruno P Hache
Darren Harvey
Erik James Hicken
Christopher F Kraser
Ellen Laird
David A Moreno
Mark C Munson
Li Ren
John E Robinson
Stephen T Schlachter
Original Assignee
Array Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Array Biopharma Inc filed Critical Array Biopharma Inc
Publication of SG11201401342VA publication Critical patent/SG11201401342VA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
SG11201401342VA 2011-10-12 2012-10-09 5,7-substituted-imidazo[1,2-c]pyrimidines SG11201401342VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161546426P 2011-10-12 2011-10-12
PCT/US2012/059282 WO2013055645A1 (en) 2011-10-12 2012-10-09 5,7-substituted-imidazo[1,2-c]pyrimidines

Publications (1)

Publication Number Publication Date
SG11201401342VA true SG11201401342VA (en) 2014-09-26

Family

ID=47071473

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201401342VA SG11201401342VA (en) 2011-10-12 2012-10-09 5,7-substituted-imidazo[1,2-c]pyrimidines

Country Status (19)

Country Link
US (1) US20140228349A1 (en)
EP (1) EP2766368A1 (en)
JP (1) JP2014528475A (en)
KR (1) KR20140076619A (en)
CN (1) CN103987713A (en)
AR (1) AR088304A1 (en)
AU (1) AU2012323399A1 (en)
BR (1) BR112014008865A2 (en)
CA (1) CA2851623A1 (en)
CL (1) CL2014000931A1 (en)
CO (1) CO6950483A2 (en)
CR (1) CR20140216A (en)
IL (1) IL231903A0 (en)
MX (1) MX2014004473A (en)
RU (1) RU2014118954A (en)
SG (1) SG11201401342VA (en)
TW (1) TW201326173A (en)
UY (1) UY34388A (en)
WO (1) WO2013055645A1 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130231340A1 (en) 2012-03-02 2013-09-05 Sareum Limited Pharmaceutical compounds
UA123854C2 (en) 2013-08-21 2021-06-16 Аліос Біофарма, Інк. Antiviral compounds
RU2652795C2 (en) * 2013-09-03 2018-05-03 Сареум Лимитед 2-phenyl-oxazole-4-carboxamide derivatives, modulating activity of jak and tyk2 kinase
SG11201704542SA (en) * 2014-12-05 2017-07-28 Array Biopharma Inc 4,6-SUBSTITUTED-PYRAZOLO[1,5-a]PYRAZINES AS JANUS KINASE INHIBITORS
AU2016208906B2 (en) 2015-01-20 2018-07-12 Wuxi Fortune Pharmaceutical Co., Ltd JAK inhibitor
CA2982493C (en) 2015-04-29 2020-01-07 Hao Wu Jak inhibitors
US10174056B2 (en) 2015-05-29 2019-01-08 Wuxi Fortune Pharmaceutical Co., Ltd Substituted pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors
ES2794779T3 (en) 2016-02-24 2020-11-19 Pfizer Pyrazolo [1,5-a] pyrazin-4-yl derivatives as JAK inhibitors
GB201617871D0 (en) 2016-10-21 2016-12-07 Sareum Limited Pharmaceutical compounds
WO2019034973A1 (en) * 2017-08-14 2019-02-21 Pfizer Inc. Pyrazolo[1,5-a]pyrazin-4-yl and related derivatives
WO2019233434A1 (en) * 2018-06-06 2019-12-12 杭州澳津生物医药技术有限公司 Pyrazolopyrimidine derivative, use thereof and pharmaceutical composition
US20220041588A1 (en) * 2018-09-27 2022-02-10 Fochon Pharmaceuticals, Ltd. Substituted imidazo[1,2-a]pyridine and [1,2,4]triazolo[1,5-a]pyridine compounds as ret kinase inhibitors
WO2020092528A1 (en) 2018-10-31 2020-05-07 Gilead Sciences, Inc. Substituted 6-azabenzimidazole compounds having hpk1 inhibitory activity
MX2021005047A (en) 2018-10-31 2021-09-08 Gilead Sciences Inc Substituted 6-azabenzimidazole compounds as hpk1 inhibitors.
CN111320624B (en) * 2018-12-14 2023-05-12 中国医药研究开发中心有限公司 Triazolopyridine and imidazopyridine compounds, and preparation method and medical application thereof
EP3954689B1 (en) * 2019-04-12 2024-04-24 Primegene (Beijing) Co., Ltd. Pyrazolopyrazine derived compounds, pharmaceutical composition and use thereof
TWI826690B (en) 2019-05-23 2023-12-21 美商基利科學股份有限公司 Substituted eneoxindoles and uses thereof
CN111039963B (en) * 2019-12-31 2021-03-19 卓和药业集团有限公司 WXFL10203614 water-soluble analogue and synthetic method thereof
WO2021173476A1 (en) * 2020-02-24 2021-09-02 The Trustees Of Columbia University In The City Of New York Compounds, pharmaceutical formulations, and methods for treatment of cancer
EP3944859A1 (en) 2020-07-30 2022-02-02 Assistance Publique Hôpitaux de Paris Method for treating immune toxicities induced by immune checkpoint inhibitors
TW202233624A (en) * 2020-11-13 2022-09-01 美商百健Ｍａ公司 Btk inhibitors
AR125588A1 (en) 2021-03-04 2023-08-02 Lilly Co Eli FGFR3 INHIBITING COMPOUNDS

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0103386A3 (en) 1998-08-21 2002-07-29 Parker Hughes Inst St Paul Use of quinazoline derivatives for producing pharmaceutical compositions having jak 3-inhibitor effect
JP2001302667A (en) * 2000-04-28 2001-10-31 Bayer Ag Imidazopyrimidine derivative and triazolopyrimidine derivative
CN103214484B (en) * 2005-12-13 2016-07-06 因塞特控股公司 Pyrrolo-[2,3-b] pyridine replaced as the heteroaryl of Janus inhibitors of kinases and pyrrolo-[2,3-b] pyrimidine
GEP20125658B (en) * 2006-11-22 2012-10-10 Incyte Corp Imidazotriazines and imidazo pyrimidines as kinase inhibitors
DE102007012645A1 (en) * 2007-03-16 2008-09-18 Bayer Healthcare Ag Substituted imidazo and triazolopyrimidines
CL2008001709A1 (en) * 2007-06-13 2008-11-03 Incyte Corp Compounds derived from pyrrolo [2,3-b] pyrimidine, jak kinase modulators; pharmaceutical composition; and use in the treatment of diseases such as cancer, psoriasis, rheumatoid arthritis, among others.
NZ603446A (en) * 2010-04-14 2014-05-30 Array Biopharma Inc 5, 7-substituted-imidazo [1, 2-c] pyrimidines as inhibitors of jak kinases

Also Published As

Publication number Publication date
KR20140076619A (en) 2014-06-20
CO6950483A2 (en) 2014-05-20
IL231903A0 (en) 2014-05-28
EP2766368A1 (en) 2014-08-20
BR112014008865A2 (en) 2017-04-25
CR20140216A (en) 2014-08-21
MX2014004473A (en) 2015-04-14
TW201326173A (en) 2013-07-01
US20140228349A1 (en) 2014-08-14
CN103987713A (en) 2014-08-13
CA2851623A1 (en) 2013-04-18
UY34388A (en) 2014-04-30
JP2014528475A (en) 2014-10-27
RU2014118954A (en) 2015-11-20
AU2012323399A1 (en) 2014-05-29
WO2013055645A1 (en) 2013-04-18
AR088304A1 (en) 2014-05-21
CL2014000931A1 (en) 2014-08-29

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