SG10202010735PA - Tau-binding antibodies - Google Patents
Tau-binding antibodiesInfo
- Publication number
- SG10202010735PA SG10202010735PA SG10202010735PA SG10202010735PA SG10202010735PA SG 10202010735P A SG10202010735P A SG 10202010735PA SG 10202010735P A SG10202010735P A SG 10202010735PA SG 10202010735P A SG10202010735P A SG 10202010735PA SG 10202010735P A SG10202010735P A SG 10202010735PA
- Authority
- SG
- Singapore
- Prior art keywords
- tau
- binding antibodies
- antibodies
- binding
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/524—CH2 domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/526—CH3 domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Animal Behavior & Ethology (AREA)
- Psychiatry (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15175522 | 2015-07-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10202010735PA true SG10202010735PA (en) | 2020-11-27 |
Family
ID=53524640
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10202010735PA SG10202010735PA (en) | 2015-07-06 | 2016-07-05 | Tau-binding antibodies |
Country Status (28)
| Country | Link |
|---|---|
| US (4) | US10287343B2 (en) |
| EP (1) | EP3319983A1 (en) |
| JP (3) | JP6630426B2 (en) |
| KR (1) | KR20180025962A (en) |
| CN (1) | CN107849104B (en) |
| AR (1) | AR105267A1 (en) |
| AU (1) | AU2016289755C1 (en) |
| BR (1) | BR112017028102A2 (en) |
| CA (1) | CA2991451A1 (en) |
| CL (1) | CL2018000043A1 (en) |
| CO (1) | CO2017012971A2 (en) |
| EA (1) | EA037092B1 (en) |
| EC (1) | ECSP18000887A (en) |
| HK (1) | HK1246804A1 (en) |
| IL (1) | IL256685B (en) |
| MA (2) | MA42377A (en) |
| MX (1) | MX2017015817A (en) |
| MY (1) | MY193677A (en) |
| NZ (1) | NZ738058A (en) |
| PE (1) | PE20180481A1 (en) |
| PH (1) | PH12017502207A1 (en) |
| SG (1) | SG10202010735PA (en) |
| TN (1) | TN2017000539A1 (en) |
| TW (1) | TWI745295B (en) |
| UA (1) | UA124616C2 (en) |
| UY (1) | UY36773A (en) |
| WO (1) | WO2017005734A1 (en) |
| ZA (1) | ZA201800027B (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2732122C2 (en) | 2015-06-05 | 2020-09-11 | Дженентек, Инк. | Anti-tau protein antibodies and methods of using said antibodies |
| BR112017028102A2 (en) | 2015-07-06 | 2018-09-04 | Ucb Biopharma Sprl | tau binding antibodies |
| EA036821B1 (en) | 2015-07-06 | 2020-12-23 | Юсб Биофарма Срл | Tau-binding antibodies |
| CR20190271A (en) | 2016-12-07 | 2019-09-03 | Genentech Inc | Anti-tau antibodies and methods of use |
| CA3045294A1 (en) | 2016-12-07 | 2018-06-14 | Genentech, Inc. | Anti-tau antibodies and methods of use |
| CN110520440A (en) | 2017-02-17 | 2019-11-29 | 戴纳立制药公司 | Anti- τ antibody and its application method |
| JOP20180014A1 (en) | 2017-02-27 | 2019-01-30 | Teijin Pharma Ltd | Humanized antibody for treating or preventing cognitive disorders, process for producing the same, and agent for treating or preventing cognitive disorders using the same |
| MA50397A (en) | 2017-10-16 | 2020-08-26 | Eisai R&D Man Co Ltd | ANTI-BODY ANTI-TAU AND THEIR USES |
| US20220017611A1 (en) * | 2018-12-13 | 2022-01-20 | INSERM (Institut National de la Santé et de la Recherche Médicale) | New anti tau svqivykpv epitope single domain antibody |
| KR20220062287A (en) * | 2019-08-13 | 2022-05-16 | 워싱턴 유니버시티 | MTBR tau isoform detection method and use thereof |
| JP7399305B2 (en) | 2020-02-12 | 2023-12-15 | イーライ リリー アンド カンパニー | Crystallization of antibodies or antigen-binding fragments |
| US20230265175A1 (en) | 2020-06-25 | 2023-08-24 | Merck Sharp & Dohme Llc | High affinity antibodies targeting tau phosphorylated at serine 413 |
| WO2023092004A1 (en) | 2021-11-17 | 2023-05-25 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of tau-related disorders |
Family Cites Families (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4741900A (en) | 1982-11-16 | 1988-05-03 | Cytogen Corporation | Antibody-metal ion complexes |
| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
| DK336987D0 (en) | 1987-07-01 | 1987-07-01 | Novo Industri As | immobilization |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| GB8719042D0 (en) | 1987-08-12 | 1987-09-16 | Parker D | Conjugate compounds |
| GB8720833D0 (en) | 1987-09-04 | 1987-10-14 | Celltech Ltd | Recombinant dna product |
| GB8907617D0 (en) | 1989-04-05 | 1989-05-17 | Celltech Ltd | Drug delivery system |
| GB8928874D0 (en) | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
| DE69233482T2 (en) | 1991-05-17 | 2006-01-12 | Merck & Co., Inc. | Method for reducing the immunogenicity of antibody variable domains |
| GB9112536D0 (en) | 1991-06-11 | 1991-07-31 | Celltech Ltd | Chemical compounds |
| GB9120467D0 (en) | 1991-09-26 | 1991-11-06 | Celltech Ltd | Anti-hmfg antibodies and process for their production |
| FR2716640B1 (en) | 1994-02-28 | 1996-05-03 | Procedes Machines Speciales | Device for centering and blocking a workpiece with a view to running it in using an expansion lapper. |
| US6372716B1 (en) | 1994-04-26 | 2002-04-16 | Genetics Institute, Inc. | Formulations for factor IX |
| US6685940B2 (en) | 1995-07-27 | 2004-02-03 | Genentech, Inc. | Protein formulation |
| GB9625640D0 (en) | 1996-12-10 | 1997-01-29 | Celltech Therapeutics Ltd | Biological products |
| US6566329B1 (en) | 1999-06-28 | 2003-05-20 | Novo Nordisk A/S | Freeze-dried preparation of human growth hormone |
| AT500379B8 (en) | 2001-02-02 | 2009-08-15 | Axon Neuroscience | TAU PROTEINS |
| US6908963B2 (en) | 2001-10-09 | 2005-06-21 | Nektar Therapeutics Al, Corporation | Thioester polymer derivatives and method of modifying the N-terminus of a polypeptide therewith |
| GB0315457D0 (en) | 2003-07-01 | 2003-08-06 | Celltech R&D Ltd | Biological products |
| CA2527020A1 (en) | 2003-07-01 | 2005-01-13 | Celltech R & D Limited | Modified antibody fab fragments |
| GB0315450D0 (en) | 2003-07-01 | 2003-08-06 | Celltech R&D Ltd | Biological products |
| GB0411186D0 (en) | 2004-05-19 | 2004-06-23 | Celltech R&D Ltd | Biological products |
| GB0412181D0 (en) | 2004-06-01 | 2004-06-30 | Celltech R&D Ltd | Biological products |
| CN1721437A (en) * | 2004-07-13 | 2006-01-18 | 中南大学 | Polypeptide antigen and antibody related to Tau protein |
| NZ612578A (en) | 2005-08-19 | 2014-11-28 | Abbvie Inc | Dual variable domain immunoglobin and uses thereof |
| GB0614780D0 (en) | 2006-07-25 | 2006-09-06 | Ucb Sa | Biological products |
| GB0619291D0 (en) | 2006-09-29 | 2006-11-08 | Ucb Sa | Altered antibodies |
| GB0624500D0 (en) * | 2006-12-07 | 2007-01-17 | Istituto Superiore Di Sanito | A novel passive vaccine for candida infections |
| EP2535351A3 (en) | 2007-09-26 | 2013-04-03 | UCB Pharma S.A. | Dual specificity antibody fusions |
| CN101307108B (en) * | 2008-06-25 | 2012-04-04 | 南京川博生物技术有限公司 | Anti-phosphorylation Tau protein antibody use for detecting AD sign abnormal phosphation Tau protein level |
| JP6063122B2 (en) | 2008-09-26 | 2017-01-18 | ユセベ ファルマ ソシエテ アノニム | Biological products |
| AU2009304560A1 (en) | 2008-10-15 | 2010-04-22 | Angiochem Inc. | Conjugates of GLP-1 agonists and uses thereof |
| BRPI0922689A2 (en) | 2008-12-05 | 2018-11-06 | Angiochem Inc. | neurotensin conjugates or neurotensin analogs and uses thereof |
| RU2011125367A (en) | 2008-12-05 | 2013-01-10 | Ангиочем Инк. | CONJUGATES OF LEPTIN AND LEPTIN ANALOGUES AND THEIR APPLICATION |
| US8609097B2 (en) | 2009-06-10 | 2013-12-17 | Hoffmann-La Roche Inc. | Use of an anti-Tau pS422 antibody for the treatment of brain diseases |
| WO2011030107A1 (en) | 2009-09-10 | 2011-03-17 | Ucb Pharma S.A. | Multivalent antibodies |
| JP2013506697A (en) | 2009-10-06 | 2013-02-28 | アンジオケム インコーポレーテッド | Compositions and methods for delivering therapeutic agents |
| US9304138B2 (en) | 2010-10-07 | 2016-04-05 | Katholieke Universiteit Leuven | Pharmaceutical composition |
| JOP20210044A1 (en) | 2010-12-30 | 2017-06-16 | Takeda Pharmaceuticals Co | Anti-cd38 antibodies |
| AU2012311234B2 (en) | 2011-09-19 | 2017-09-28 | Axon Neuroscience Se | Protein-based therapy and diagnosis of tau-mediated pathology in Alzheimer's disease |
| EP2776466B1 (en) | 2011-11-11 | 2017-08-23 | UCB Biopharma SPRL | Albumin binding antibodies and binding fragments thereof |
| UA114902C2 (en) | 2011-12-20 | 2017-08-28 | Янссен Байотек, Інк. | Anti-phf-tau antibodies and their uses |
| US9834596B2 (en) * | 2012-07-03 | 2017-12-05 | Washington University | Antibodies to tau |
| GB2507207A (en) | 2012-08-16 | 2014-04-23 | Ipierian Inc | Treatment of Tauopathies |
| MY184251A (en) | 2012-12-21 | 2021-03-29 | Biogen Int Neuroscience Gmbh | Human anti-tau antibodies |
| CA2874083C (en) * | 2014-12-05 | 2024-01-02 | Universite Laval | Tdp-43-binding polypeptides useful for the treatment of neurodegenerative diseases |
| EA036821B1 (en) | 2015-07-06 | 2020-12-23 | Юсб Биофарма Срл | Tau-binding antibodies |
| BR112017028102A2 (en) | 2015-07-06 | 2018-09-04 | Ucb Biopharma Sprl | tau binding antibodies |
-
2016
- 2016-07-05 BR BR112017028102A patent/BR112017028102A2/en active Search and Examination
- 2016-07-05 CA CA2991451A patent/CA2991451A1/en active Pending
- 2016-07-05 WO PCT/EP2016/065813 patent/WO2017005734A1/en active Application Filing
- 2016-07-05 EP EP16734676.6A patent/EP3319983A1/en active Pending
- 2016-07-05 MX MX2017015817A patent/MX2017015817A/en unknown
- 2016-07-05 TN TNP/2017/000539A patent/TN2017000539A1/en unknown
- 2016-07-05 SG SG10202010735PA patent/SG10202010735PA/en unknown
- 2016-07-05 CN CN201680039795.4A patent/CN107849104B/en active Active
- 2016-07-05 JP JP2018500423A patent/JP6630426B2/en active Active
- 2016-07-05 AU AU2016289755A patent/AU2016289755C1/en active Active
- 2016-07-05 MA MA042377A patent/MA42377A/en unknown
- 2016-07-05 MY MYPI2018700043A patent/MY193677A/en unknown
- 2016-07-05 US US15/742,087 patent/US10287343B2/en active Active
- 2016-07-05 NZ NZ738058A patent/NZ738058A/en unknown
- 2016-07-05 EA EA201890172A patent/EA037092B1/en not_active IP Right Cessation
- 2016-07-05 PE PE2017002750A patent/PE20180481A1/en unknown
- 2016-07-05 UA UAA201711739A patent/UA124616C2/en unknown
- 2016-07-05 MA MA41670A patent/MA41670A1/en unknown
- 2016-07-05 KR KR1020187003689A patent/KR20180025962A/en not_active Application Discontinuation
- 2016-07-06 AR ARP160102045A patent/AR105267A1/en unknown
- 2016-07-06 UY UY0001036773A patent/UY36773A/en not_active Application Discontinuation
- 2016-07-06 TW TW105121455A patent/TWI745295B/en active
-
2017
- 2017-12-04 PH PH12017502207A patent/PH12017502207A1/en unknown
- 2017-12-18 CO CONC2017/0012971A patent/CO2017012971A2/en unknown
-
2018
- 2018-01-01 IL IL256685A patent/IL256685B/en unknown
- 2018-01-03 ZA ZA2018/00027A patent/ZA201800027B/en unknown
- 2018-01-05 CL CL2018000043A patent/CL2018000043A1/en unknown
- 2018-01-05 EC ECIEPI2018887A patent/ECSP18000887A/en unknown
- 2018-05-10 HK HK18106080.8A patent/HK1246804A1/en unknown
-
2019
- 2019-05-13 US US16/409,945 patent/US10889640B2/en active Active
- 2019-12-06 JP JP2019220807A patent/JP7100008B2/en active Active
-
2020
- 2020-12-29 US US17/136,189 patent/US11732034B2/en active Active
-
2022
- 2022-06-30 JP JP2022105415A patent/JP7413448B2/en active Active
-
2023
- 2023-06-30 US US18/344,945 patent/US20230416350A1/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1253507A1 (en) | Anti-ror1 antibodies | |
| HK1254836A1 (en) | Anti-ror1 antibodies | |
| HK1256116A1 (en) | Anti-lag-3 antibodies | |
| GB201521391D0 (en) | Antibodies | |
| GB201521393D0 (en) | Antibodies | |
| HK1246804A1 (en) | Tau-binding antibodies | |
| ZA201705663B (en) | Anti-transthyretin antibodies | |
| GB201521382D0 (en) | Antibodies | |
| ZA201705662B (en) | Anti-transthyretin antibodies | |
| IL255323A0 (en) | Anti-fcrn antibodies | |
| HK1255056A1 (en) | Anti-cd115 antibodies | |
| SG11201706126WA (en) | Anti-transthyretin antibodies | |
| GB201509907D0 (en) | Antibodies | |
| GB201522394D0 (en) | Antibodies | |
| GB201503438D0 (en) | Antibodies | |
| IL284022A (en) | Anti-transthyretin antibodies | |
| GB201518728D0 (en) | Antibodies | |
| GB201515572D0 (en) | Anti-LAG-3 antibodies | |
| GB201515570D0 (en) | Anti-LAG-3 antibodies | |
| GB201514425D0 (en) | Antibodies | |
| GB201508444D0 (en) | Antibodies | |
| GB201508437D0 (en) | Antibodies | |
| GB201507541D0 (en) | Antibodies | |
| GB201504858D0 (en) | Antibodies | |
| GB201502591D0 (en) | Antibodies |