SG10202010279YA - Compositions and methods of inhibiting masp-3 for the treatment of various diseases and disorders - Google Patents
Compositions and methods of inhibiting masp-3 for the treatment of various diseases and disordersInfo
- Publication number
- SG10202010279YA SG10202010279YA SG10202010279YA SG10202010279YA SG10202010279YA SG 10202010279Y A SG10202010279Y A SG 10202010279YA SG 10202010279Y A SG10202010279Y A SG 10202010279YA SG 10202010279Y A SG10202010279Y A SG 10202010279YA SG 10202010279Y A SG10202010279Y A SG 10202010279YA
- Authority
- SG
- Singapore
- Prior art keywords
- disorders
- compositions
- treatment
- methods
- various diseases
- Prior art date
Links
- 208000037765 diseases and disorders Diseases 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y25/00—Nanomagnetism, e.g. magnetoimpedance, anisotropic magnetoresistance, giant magnetoresistance or tunneling magnetoresistance
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- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01F—COMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM, CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THE RARE-EARTH METALS
- C01F17/00—Compounds of rare earth metals
- C01F17/20—Compounds containing only rare earth metals as the metal element
- C01F17/206—Compounds containing only rare earth metals as the metal element oxide or hydroxide being the only anion
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21104—Mannan-binding lectin-associated serine protease-2 (3.4.21.104)
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
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- H01F1/0036—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties showing low dimensional magnetism, i.e. spin rearrangements due to a restriction of dimensions, e.g. showing giant magnetoresistivity
- H01F1/0045—Zero dimensional, e.g. nanoparticles, soft nanoparticles for medical/biological use
- H01F1/0054—Coated nanoparticles, e.g. nanoparticles coated with organic surfactant
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- C01P2002/54—Solid solutions containing elements as dopants one element only
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- C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
- C01P2004/00—Particle morphology
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- C01P2004/64—Nanometer sized, i.e. from 1-100 nanometer
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/734—Complement-dependent cytotoxicity [CDC]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662369674P | 2016-08-01 | 2016-08-01 | |
| US201662419420P | 2016-11-08 | 2016-11-08 | |
| US201762478336P | 2017-03-29 | 2017-03-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10202010279YA true SG10202010279YA (en) | 2020-11-27 |
Family
ID=61073545
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10202010279YA SG10202010279YA (en) | 2016-08-01 | 2017-07-31 | Compositions and methods of inhibiting masp-3 for the treatment of various diseases and disorders |
| SG10202010277SA SG10202010277SA (en) | 2016-08-01 | 2017-07-31 | Compositions and methods of inhibiting masp-3 for the treatment of various diseases and disorders |
| SG11201900606VA SG11201900606VA (en) | 2016-08-01 | 2017-07-31 | Compositions and methods of inhibiting masp-3 for the treatment of various diseases and disorders |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10202010277SA SG10202010277SA (en) | 2016-08-01 | 2017-07-31 | Compositions and methods of inhibiting masp-3 for the treatment of various diseases and disorders |
| SG11201900606VA SG11201900606VA (en) | 2016-08-01 | 2017-07-31 | Compositions and methods of inhibiting masp-3 for the treatment of various diseases and disorders |
Country Status (25)
| Country | Link |
|---|---|
| US (4) | US10639369B2 (en) |
| EP (1) | EP3490603A4 (en) |
| JP (3) | JP6971306B2 (en) |
| KR (3) | KR102553777B1 (en) |
| CN (4) | CN116333146A (en) |
| AU (4) | AU2017306069B2 (en) |
| BR (1) | BR112019001247A2 (en) |
| CA (3) | CA3122348A1 (en) |
| CL (1) | CL2019000230A1 (en) |
| CO (1) | CO2019001212A2 (en) |
| CR (1) | CR20190105A (en) |
| CU (1) | CU24568B1 (en) |
| EC (1) | ECSP19015192A (en) |
| GE (1) | GEP20247593B (en) |
| IL (3) | IL298690B2 (en) |
| JO (6) | JOP20170154B1 (en) |
| MA (1) | MA45798A (en) |
| MX (3) | MX2019000965A (en) |
| PE (1) | PE20190389A1 (en) |
| PH (1) | PH12019500204A1 (en) |
| SA (1) | SA519400950B1 (en) |
| SG (3) | SG10202010279YA (en) |
| TW (4) | TW202334243A (en) |
| UY (1) | UY37349A (en) |
| WO (1) | WO2018026722A1 (en) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017035405A1 (en) | 2015-08-26 | 2017-03-02 | Achillion Pharmaceuticals, Inc. | Amino compounds for treatment of immune and inflammatory disorders |
| WO2017035401A1 (en) | 2015-08-26 | 2017-03-02 | Achillion Pharmaceuticals, Inc. | Amide compounds for treatment of immune and inflammatory disorders |
| WO2018160891A1 (en) | 2017-03-01 | 2018-09-07 | Achillion Pharmaceutical, Inc. | Pharmaceutical compounds for treatment of medical disorders |
| KR102632860B1 (en) | 2017-03-01 | 2024-02-02 | 아칠리온 파르마세우티칼스 인코포레이티드 | Aryl, heteroaryl, and heterocyclic pharmaceutical compounds for the treatment of medical disorders |
| US20210215714A1 (en) * | 2018-05-25 | 2021-07-15 | Achillion Pharmaceuticals, Inc. | Complement alternative pathway-associated nephropathy biomarkers |
| KR20210057086A (en) | 2018-09-06 | 2021-05-20 | 아칠리온 파르마세우티칼스 인코포레이티드 | The morphological form of Danicopan |
| JP7443375B2 (en) | 2018-09-06 | 2024-03-05 | アキリオン ファーマシューティカルズ， インコーポレーテッド | Macrocyclic compounds for the treatment of medical disorders |
| KR20210093855A (en) | 2018-09-25 | 2021-07-28 | 아칠리온 파르마세우티칼스 인코포레이티드 | Conformational forms of complement factor D inhibitors |
| CN110244053B (en) * | 2019-05-09 | 2022-03-11 | 北京大学第三医院（北京大学第三临床医学院） | Molecular marker for diagnosing lupus nephritis and pulmonary hypertension disease and application thereof |
| CN112812182B (en) * | 2019-11-15 | 2023-01-06 | 深圳宾德生物技术有限公司 | FGFR 4-targeted single-chain antibody, chimeric antigen receptor T cell, and preparation method and application thereof |
| KR20220131233A (en) * | 2020-01-21 | 2022-09-27 | 상하이 바이오트로이 바이오테크니크 컴퍼니, 리미티드 | SEMG2 antibody and uses thereof |
| JP2023538914A (en) * | 2020-08-18 | 2023-09-12 | オメロス コーポレーション | Monoclonal antibodies, compositions, and methods for detecting complement factor D |
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