SG10202003090VA - PI3K δ INHIBITOR - Google Patents

PI3K δ INHIBITOR

Info

Publication number
SG10202003090VA
SG10202003090VA SG10202003090VA SG10202003090VA SG10202003090VA SG 10202003090V A SG10202003090V A SG 10202003090VA SG 10202003090V A SG10202003090V A SG 10202003090VA SG 10202003090V A SG10202003090V A SG 10202003090VA SG 10202003090V A SG10202003090V A SG 10202003090VA
Authority
SG
Singapore
Prior art keywords
pi3k
inhibitor
Prior art date
Application number
SG10202003090VA
Inventor
Li Li
Yan Zhang
Original Assignee
Kbp Biosciences Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kbp Biosciences Co Ltd filed Critical Kbp Biosciences Co Ltd
Publication of SG10202003090VA publication Critical patent/SG10202003090VA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
SG10202003090VA 2012-08-08 2013-08-08 PI3K δ INHIBITOR SG10202003090VA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201210279961 2012-08-08
CN201210529334 2012-12-10
CN201310130010 2013-04-16

Publications (1)

Publication Number Publication Date
SG10202003090VA true SG10202003090VA (en) 2020-05-28

Family

ID=50067418

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201501173SA SG11201501173SA (en) 2012-08-08 2013-08-08 PI3Kδ INHIBITOR
SG10202003090VA SG10202003090VA (en) 2012-08-08 2013-08-08 PI3K δ INHIBITOR

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG11201501173SA SG11201501173SA (en) 2012-08-08 2013-08-08 PI3Kδ INHIBITOR

Country Status (3)

Country Link
CN (1) CN104768952B (en)
SG (2) SG11201501173SA (en)
WO (1) WO2014023083A1 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6667300B2 (en) 2000-04-25 2003-12-23 Icos Corporation Inhibitors of human phosphatidylinositol 3-kinase delta
US7932260B2 (en) 2004-05-13 2011-04-26 Icos Corporation Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta
MY184292A (en) 2013-09-22 2021-03-30 Sunshine Lake Pharma Co Ltd Substituted aminopyrimidine compounds and methods of use
JP2017502021A (en) 2013-12-20 2017-01-19 ギリアード カリストガ エルエルシー Process method for phosphatidylinositol 3-kinase inhibitors
AU2014364414A1 (en) 2013-12-20 2016-06-30 Gilead Calistoga Llc Polymorphic forms of a hydrochloride salt of (S) -2-(1-(9H-purin-6-ylamino) propyl) -5-fluoro-3-phenylquinazolin-4 (3H) -one
EP3154960A1 (en) * 2014-06-13 2017-04-19 Gilead Sciences, Inc. Phosphatidylinositol 3-kinase inhibitors
CN106660994A (en) 2014-06-13 2017-05-10 吉利德科学公司 Phosphatidylinositol 3-kinase inhibitors
ES2763104T3 (en) 2014-06-13 2020-05-27 Gilead Sciences Inc Quinazolinone derivatives as phosphatidylinositol 3-kinase inhibitors
EA201692249A1 (en) * 2014-06-13 2017-05-31 Джилид Сайэнс, Инк. PHOSPHATIDYLINOSITOL-3-KINASE INHIBITORS
MA40250A (en) 2014-07-04 2017-05-10 Lupin Ltd Quinolizinone derivatives as pi3k inhibitors
WO2016054491A1 (en) 2014-10-03 2016-04-07 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
US10919914B2 (en) 2016-06-08 2021-02-16 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
KR101932146B1 (en) * 2016-07-14 2018-12-24 주식회사 바이오웨이 Novel Quinazolinone derivatives as PI3K inhibitors, and pharmaceutical composition comprising the same
TW201815787A (en) 2016-09-23 2018-05-01 美商基利科學股份有限公司 Phosphatidylinositol 3-kinase inhibitors
TW201813963A (en) 2016-09-23 2018-04-16 美商基利科學股份有限公司 Phosphatidylinositol 3-kinase inhibitors
TW201825465A (en) 2016-09-23 2018-07-16 美商基利科學股份有限公司 Phosphatidylinositol 3-kinase inhibitors
CN108003190B (en) * 2017-12-27 2020-06-12 东南大学 Preparation method of glufosinate-ammonium
US10751339B2 (en) 2018-01-20 2020-08-25 Sunshine Lake Pharma Co., Ltd. Substituted aminopyrimidine compounds and methods of use
CN110283174B (en) * 2019-07-31 2021-07-23 安徽中医药大学 PI3K delta inhibitor and application thereof
CN111440173B (en) * 2020-03-27 2021-05-14 山东大学 Preparation method of PI3K inhibitor
CN115304600B (en) * 2022-09-29 2023-01-13 北京鑫开元医药科技有限公司 mTOR inhibitor, preparation method and application

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001081346A2 (en) * 2000-04-25 2001-11-01 Icos Corporation Inhibitors of human phosphatidyl-inositol 3-kinase delta
US7932260B2 (en) * 2004-05-13 2011-04-26 Icos Corporation Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta
CN101123968A (en) * 2004-06-04 2008-02-13 艾科斯有限公司 Methods for treating mast cell disorders
CA2716334A1 (en) * 2007-11-13 2009-05-22 Icos Corporation Inhibitors of human phosphatidyl-inositol 3-kinase delta
NZ587051A (en) * 2008-01-04 2012-12-21 Intellikine Llc Isoquinolinone derivatives, compositions and methods of inhibiting phosphatidyl inositol-3 kinase (pi3 kinase)
CN102838601A (en) * 2011-06-24 2012-12-26 山东亨利医药科技有限责任公司 Selective phosphatidylinositol-3 kinase delta inhibitor

Also Published As

Publication number Publication date
CN104768952A (en) 2015-07-08
SG11201501173SA (en) 2015-05-28
CN104768952B (en) 2016-10-19
WO2014023083A1 (en) 2014-02-13

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