SG10201907682RA - System and method for providing patient-specific dosing as a function of mathematical models - Google Patents

System and method for providing patient-specific dosing as a function of mathematical models

Info

Publication number
SG10201907682RA
SG10201907682RA SG10201907682RA SG10201907682RA SG 10201907682R A SG10201907682R A SG 10201907682RA SG 10201907682R A SG10201907682R A SG 10201907682RA SG 10201907682R A SG10201907682R A SG 10201907682RA
Authority
SG
Singapore
Prior art keywords
patient
specific
function
responses
mathematical models
Prior art date
Application number
Inventor
Mould Diane
Original Assignee
Mould Diane
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mould Diane filed Critical Mould Diane
Publication of SG10201907682RA publication Critical patent/SG10201907682RA/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N7/00—Computing arrangements based on specific mathematical models
    • G06N7/01—Probabilistic graphical models, e.g. probabilistic networks
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders

Abstract

SYSTEM AND METHOD FOR PROVIDING PATIENT-SPECIFIC DOSING AS A FUNCTION OF MATHEMATICAL MODELS [0001] A system and method for predicting, proposing and/or evaluating suitable medication dosing regimens for a specific individual as a function of individual-specific characteristics and observed responses of the specific individual. Mathematical models of observed patient responses are used in determining an initial dose. The system and method use the patient’s observed response to the initial dose to refine the model for use to forecast expected responses to proposed dosing regimens more accurately for a specific patient. More specifically, the system and method uses Bayesian averaging, Bayesian updating and Bayesian forecasting techniques to develop patient-specific dosing regimens as a function of not only generic mathematical models and patient- specific characteristics accounted for in the models as covariate patient factors, but also observed patient-specific responses that are not accounted for within the models themselves, and that reflect variability that distinguishes the specific patient from the typical patient reflected by the model. Fig. 2
SG10201907682R 2012-10-05 2013-10-07 System and method for providing patient-specific dosing as a function of mathematical models SG10201907682RA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261710330P 2012-10-05 2012-10-05

Publications (1)

Publication Number Publication Date
SG10201907682RA true SG10201907682RA (en) 2019-10-30

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201907682R SG10201907682RA (en) 2012-10-05 2013-10-07 System and method for providing patient-specific dosing as a function of mathematical models
SG11201502616WA SG11201502616WA (en) 2012-10-05 2013-10-07 System and method for providing patient-specific dosing as a function of mathematical models

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201502616WA SG11201502616WA (en) 2012-10-05 2013-10-07 System and method for providing patient-specific dosing as a function of mathematical models

Country Status (10)

Country Link
US (6) US10083400B2 (en)
EP (2) EP4224482A1 (en)
JP (4) JP6412499B2 (en)
KR (3) KR102370479B1 (en)
AU (4) AU2013326801A1 (en)
CA (1) CA2887072C (en)
HK (1) HK1213983A1 (en)
IL (3) IL238115B (en)
SG (2) SG10201907682RA (en)
WO (1) WO2014055978A1 (en)

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KR20220032641A (en) 2022-03-15
JP6653365B2 (en) 2020-02-26
EP2904388B1 (en) 2023-06-07
JP2016500866A (en) 2016-01-14
US10083400B2 (en) 2018-09-25
KR20150100626A (en) 2015-09-02
US20140351197A1 (en) 2014-11-27
US20220044782A1 (en) 2022-02-10
IL264125B (en) 2020-03-31
US20140100829A1 (en) 2014-04-10
KR102450486B1 (en) 2022-10-04
AU2013326801A1 (en) 2015-04-16
KR20210025697A (en) 2021-03-09
SG11201502616WA (en) 2015-05-28
IL272760B (en) 2022-03-01
US10740687B2 (en) 2020-08-11
KR102370479B1 (en) 2022-03-04
JP2022111352A (en) 2022-07-29
US20180032892A1 (en) 2018-02-01
AU2019232874A1 (en) 2019-10-10
AU2021245151A1 (en) 2021-11-04
JP2020080161A (en) 2020-05-28
EP2904388C0 (en) 2023-06-07
KR102223018B1 (en) 2021-03-05
US10268966B2 (en) 2019-04-23
WO2014055978A1 (en) 2014-04-10
CA2887072A1 (en) 2014-04-10
US10706364B2 (en) 2020-07-07
US20190171962A1 (en) 2019-06-06
CA2887072C (en) 2024-04-16
HK1213983A1 (en) 2016-07-15
AU2023278028A1 (en) 2023-12-21
US11373743B2 (en) 2022-06-28
EP4224482A1 (en) 2023-08-09
IL272760A (en) 2020-04-30
IL238115B (en) 2019-01-31
JP6412499B2 (en) 2018-10-24
EP2904388A1 (en) 2015-08-12
JP2019016388A (en) 2019-01-31
IL264125A (en) 2019-01-31
EP2904388A4 (en) 2016-06-22
US20200334561A1 (en) 2020-10-22

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