SG10201900455YA - Bcma chimeric antigen receptors - Google Patents

Bcma chimeric antigen receptors

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Publication number
SG10201900455YA
SG10201900455YA SG10201900455YA SG10201900455YA SG10201900455YA SG 10201900455Y A SG10201900455Y A SG 10201900455YA SG 10201900455Y A SG10201900455Y A SG 10201900455YA SG 10201900455Y A SG10201900455Y A SG 10201900455YA SG 10201900455Y A SG10201900455Y A SG 10201900455YA
Authority
SG
Singapore
Prior art keywords
antigen receptors
chimeric antigen
bcma chimeric
bcma
cell
Prior art date
Application number
SG10201900455YA
Inventor
Richard Morgan
Kevin Friedman
Original Assignee
Bluebird Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bluebird Bio Inc filed Critical Bluebird Bio Inc
Publication of SG10201900455YA publication Critical patent/SG10201900455YA/en

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    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • AHUMAN NECESSITIES
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    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
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    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
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    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • A61K39/461Cellular immunotherapy characterised by the cell type used
    • A61K39/4611T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
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Abstract

BCMACHIMERIC ANTIGEN RECEPTORS The invention provides for B cell related conditions. improved compositions for adoptive T cell therapies (FIG. ) 109
SG10201900455YA 2014-07-24 2015-07-23 Bcma chimeric antigen receptors SG10201900455YA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462028664P 2014-07-24 2014-07-24
US201462044103P 2014-08-29 2014-08-29
US201562152575P 2015-04-24 2015-04-24

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SG10201900455YA true SG10201900455YA (en) 2019-02-27

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SG10201900455YA SG10201900455YA (en) 2014-07-24 2015-07-23 Bcma chimeric antigen receptors

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US (2) US20170226216A1 (en)
EP (1) EP3172231B1 (en)
JP (1) JP6706244B2 (en)
KR (1) KR102523934B1 (en)
CN (1) CN106795217B (en)
AU (1) AU2015292590B2 (en)
CA (1) CA2956002C (en)
ES (1) ES2878449T3 (en)
IL (1) IL250202B (en)
MX (1) MX2017001079A (en)
RU (1) RU2747457C2 (en)
SG (2) SG11201700492SA (en)
WO (1) WO2016014789A2 (en)
ZA (1) ZA201700730B (en)

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CA2946585C (en) * 2014-04-25 2023-09-19 Bluebird Bio, Inc. Mnd promoter chimeric antigen receptors
WO2015179801A1 (en) 2014-05-23 2015-11-26 University Of Florida Research Foundation, Inc. Car based immunotherapy
RS61406B1 (en) 2014-06-06 2021-03-31 Bluebird Bio Inc Improved t cell compositions
IL252617B (en) 2014-12-05 2022-09-01 Memorial Sloan Kettering Cancer Center Chimeric antigen receptors targeting b-cell maturation antigen and uses thereof
SG11201704548PA (en) 2014-12-05 2017-07-28 Memorial Sloan Kettering Cancer Center Antibodies targeting b-cell maturation antigen and methods of use
CN112358551B (en) 2014-12-12 2024-02-02 2赛文缇生物公司 BCMA chimeric antigen receptor
US10647778B2 (en) * 2015-02-09 2020-05-12 University Of Florida Research Foundation, Incorporated Bi-specific chimeric antigen receptor and uses thereof
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