SG10201809312QA - Nucleic acid synthesis techniques - Google Patents
Nucleic acid synthesis techniquesInfo
- Publication number
- SG10201809312QA SG10201809312QA SG10201809312QA SG10201809312QA SG10201809312QA SG 10201809312Q A SG10201809312Q A SG 10201809312QA SG 10201809312Q A SG10201809312Q A SG 10201809312QA SG 10201809312Q A SG10201809312Q A SG 10201809312QA SG 10201809312Q A SG10201809312Q A SG 10201809312QA
- Authority
- SG
- Singapore
- Prior art keywords
- nucleic acid
- acid fragments
- synthesis techniques
- amplified
- synthesized
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00585—Parallel processes
- B01J2219/00587—High throughput processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00686—Automatic
- B01J2219/00689—Automatic using computers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00693—Means for quality control
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00695—Synthesis control routines, e.g. using computer programs
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00698—Measurement and control of process parameters
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00702—Processes involving means for analysing and characterising the products
- B01J2219/00704—Processes involving means for analysing and characterising the products integrated with the reactor apparatus
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00722—Nucleotides
Abstract
NUCLEIC ACID SYNTHESIS TECHNIQUES A method for synthesizing a nucleic acid includes synthesizing one or more nucleic acid fragments on a substrate. The synthesized one or more nucleic acid fragments may be amplified on the substrate. The method also includes sequencing the synthesized or amplified one or more nucleic acid fragments on the substrate. The sequencing may provide feedback to designs of the one or more nucleic acid fragments. The method further includes harvesting the synthesized or amplified one or more nucleic acid fragments based on sequencing. The synthesized or amplified one or more nucleic acid fragments may be assembled to generate a target nucleic acid. FIG. 60
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461994498P | 2014-05-16 | 2014-05-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201809312QA true SG10201809312QA (en) | 2018-11-29 |
Family
ID=53433257
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201809312QA SG10201809312QA (en) | 2014-05-16 | 2015-05-14 | Nucleic acid synthesis techniques |
SG11201610168YA SG11201610168YA (en) | 2014-05-16 | 2015-05-14 | Nucleic acid synthesis techniques |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201610168YA SG11201610168YA (en) | 2014-05-16 | 2015-05-14 | Nucleic acid synthesis techniques |
Country Status (9)
Country | Link |
---|---|
US (2) | US10570447B2 (en) |
EP (1) | EP3143161B1 (en) |
CN (1) | CN106536734B (en) |
AU (1) | AU2015259024B2 (en) |
CA (2) | CA3219413A1 (en) |
DK (1) | DK3143161T3 (en) |
ES (1) | ES2876432T3 (en) |
SG (2) | SG10201809312QA (en) |
WO (1) | WO2015175832A1 (en) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI721929B (en) | 2013-08-05 | 2021-03-11 | 美商扭轉生物科技有限公司 | De novo synthesized gene libraries |
US20150361422A1 (en) * | 2014-06-16 | 2015-12-17 | Agilent Technologies, Inc. | High throughput gene assembly in droplets |
CA2975852A1 (en) | 2015-02-04 | 2016-08-11 | Twist Bioscience Corporation | Methods and devices for de novo oligonucleic acid assembly |
WO2016126987A1 (en) | 2015-02-04 | 2016-08-11 | Twist Bioscience Corporation | Compositions and methods for synthetic gene assembly |
WO2016172377A1 (en) | 2015-04-21 | 2016-10-27 | Twist Bioscience Corporation | Devices and methods for oligonucleic acid library synthesis |
IL258164B (en) | 2015-09-18 | 2022-09-01 | Twist Bioscience Corp | Methods for modulating protein and cellular activity and method for nucleic acid synthesis |
WO2017053450A1 (en) | 2015-09-22 | 2017-03-30 | Twist Bioscience Corporation | Flexible substrates for nucleic acid synthesis |
CN108603307A (en) | 2015-12-01 | 2018-09-28 | 特韦斯特生物科学公司 | functionalized surface and its preparation |
WO2018038772A1 (en) | 2016-08-22 | 2018-03-01 | Twist Bioscience Corporation | De novo synthesized nucleic acid libraries |
JP6871364B2 (en) | 2016-09-21 | 2021-05-12 | ツイスト バイオサイエンス コーポレーション | Nucleic acid-based data storage |
US11667951B2 (en) | 2016-10-24 | 2023-06-06 | Geneinfosec, Inc. | Concealing information present within nucleic acids |
EA201991262A1 (en) | 2016-12-16 | 2020-04-07 | Твист Байосайенс Корпорейшн | LIBRARIES OF OPTIONS OF IMMUNOLOGICAL SYNAPSIS AND THEIR SYNTHESIS |
GB201704754D0 (en) | 2017-01-05 | 2017-05-10 | Illumina Inc | Kinetic exclusion amplification of nucleic acid libraries |
SG11201907713WA (en) | 2017-02-22 | 2019-09-27 | Twist Bioscience Corp | Nucleic acid based data storage |
EP3595674A4 (en) | 2017-03-15 | 2020-12-16 | Twist Bioscience Corporation | Variant libraries of the immunological synapse and synthesis thereof |
CN111566209A (en) | 2017-06-12 | 2020-08-21 | 特韦斯特生物科学公司 | Seamless nucleic acid assembly method |
WO2018231864A1 (en) | 2017-06-12 | 2018-12-20 | Twist Bioscience Corporation | Methods for seamless nucleic acid assembly |
US11407837B2 (en) | 2017-09-11 | 2022-08-09 | Twist Bioscience Corporation | GPCR binding proteins and synthesis thereof |
KR20240024357A (en) | 2017-10-20 | 2024-02-23 | 트위스트 바이오사이언스 코포레이션 | Heated nanowells for polynucleotide synthesis |
US10936953B2 (en) | 2018-01-04 | 2021-03-02 | Twist Bioscience Corporation | DNA-based digital information storage with sidewall electrodes |
KR20210013128A (en) | 2018-05-18 | 2021-02-03 | 트위스트 바이오사이언스 코포레이션 | Polynucleotides, reagents and methods for nucleic acid hybridization |
CN113272449B (en) * | 2018-10-26 | 2024-03-12 | Illumina公司 | Polymer beads are adapted for DNA treatment |
SG11202109283UA (en) | 2019-02-26 | 2021-09-29 | Twist Bioscience Corp | Variant nucleic acid libraries for antibody optimization |
AU2020229349A1 (en) | 2019-02-26 | 2021-10-14 | Twist Bioscience Corporation | Variant nucleic acid libraries for GLP1 receptor |
GB201903056D0 (en) * | 2019-03-07 | 2019-04-24 | Nuclera Nucleics Ltd | Method of oligonucleotide synthesis |
GB201907209D0 (en) * | 2019-05-22 | 2019-07-03 | Nuclera Nucleics Ltd | Method of quality control of oligonucleotide synthesis |
SG11202012826XA (en) * | 2019-05-31 | 2021-01-28 | Illumina Inc | Systems and methods for information storage and retrieval using flow cells |
EP3987019A4 (en) | 2019-06-21 | 2023-04-19 | Twist Bioscience Corporation | Barcode-based nucleic acid sequence assembly |
WO2021137845A1 (en) * | 2019-12-30 | 2021-07-08 | Dna Syntech Inc. | Method for preparing nucleic acid sequences using enzyme |
WO2022170705A1 (en) * | 2021-02-10 | 2022-08-18 | 清华大学 | Method for preparing long-chain rna modified at specific site |
EP4298246A1 (en) | 2021-02-26 | 2024-01-03 | Avery Digital Data, Inc. | Semiconductor chip devices and methods for polynucleotide synthesis |
EP4352286A1 (en) * | 2021-06-11 | 2024-04-17 | Cellanome, Inc. | Systems and methods for analyzing biological samples |
WO2023043972A1 (en) * | 2021-09-17 | 2023-03-23 | Nutcracker Therapeutics, Inc. | Systems and methods for generating nucleotide sequence synthesis related metrics |
WO2023116712A1 (en) * | 2021-12-20 | 2023-06-29 | 英诺维尔智能科技(苏州)有限公司 | High-throughput nucleic acid synthesis chip and use method thereof |
Family Cites Families (59)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0450060A1 (en) | 1989-10-26 | 1991-10-09 | Sri International | Dna sequencing |
SE9400522D0 (en) | 1994-02-16 | 1994-02-16 | Ulf Landegren | Method and reagent for detecting specific nucleotide sequences |
US5641658A (en) | 1994-08-03 | 1997-06-24 | Mosaic Technologies, Inc. | Method for performing amplification of nucleic acid with two primers bound to a single solid support |
US5846719A (en) | 1994-10-13 | 1998-12-08 | Lynx Therapeutics, Inc. | Oligonucleotide tags for sorting and identification |
WO1996018205A1 (en) | 1994-12-08 | 1996-06-13 | Molecular Dynamics, Inc. | Fluorescence imaging system employing a macro scanning objective |
US5750341A (en) | 1995-04-17 | 1998-05-12 | Lynx Therapeutics, Inc. | DNA sequencing by parallel oligonucleotide extensions |
US5528050A (en) | 1995-07-24 | 1996-06-18 | Molecular Dynamics, Inc. | Compact scan head with multiple scanning modalities |
DE69636080T2 (en) | 1995-12-05 | 2006-11-30 | Erland Jorn Koch | A cascading amplification reaction of nucleic acids |
GB9620209D0 (en) | 1996-09-27 | 1996-11-13 | Cemu Bioteknik Ab | Method of sequencing DNA |
GB9626815D0 (en) | 1996-12-23 | 1997-02-12 | Cemu Bioteknik Ab | Method of sequencing DNA |
ATE269908T1 (en) | 1997-04-01 | 2004-07-15 | Manteia S A | METHOD FOR SEQUENCING NUCLEIC ACIDS |
DE69837913T2 (en) * | 1997-04-01 | 2008-02-07 | Solexa Ltd., Saffron Walden | PROCESS FOR THE MAKING OF NUCLEIC ACID |
US6969488B2 (en) | 1998-05-22 | 2005-11-29 | Solexa, Inc. | System and apparatus for sequential processing of analytes |
US6124120A (en) | 1997-10-08 | 2000-09-26 | Yale University | Multiple displacement amplification |
AR021833A1 (en) | 1998-09-30 | 2002-08-07 | Applied Research Systems | METHODS OF AMPLIFICATION AND SEQUENCING OF NUCLEIC ACID |
US6274320B1 (en) | 1999-09-16 | 2001-08-14 | Curagen Corporation | Method of sequencing a nucleic acid |
WO2002004680A2 (en) | 2000-07-07 | 2002-01-17 | Visigen Biotechnologies, Inc. | Real-time sequence determination |
US7211414B2 (en) | 2000-12-01 | 2007-05-01 | Visigen Biotechnologies, Inc. | Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity |
AR031640A1 (en) | 2000-12-08 | 2003-09-24 | Applied Research Systems | ISOTHERMAL AMPLIFICATION OF NUCLEIC ACIDS IN A SOLID SUPPORT |
US7057026B2 (en) | 2001-12-04 | 2006-06-06 | Solexa Limited | Labelled nucleotides |
US20040002090A1 (en) | 2002-03-05 | 2004-01-01 | Pascal Mayer | Methods for detecting genome-wide sequence variations associated with a phenotype |
EP3795577A1 (en) | 2002-08-23 | 2021-03-24 | Illumina Cambridge Limited | Modified nucleotides |
CA2513985C (en) | 2003-01-21 | 2012-05-29 | Illumina Inc. | Chemical reaction monitor |
WO2005003304A2 (en) | 2003-06-20 | 2005-01-13 | Illumina, Inc. | Methods and compositions for whole genome amplification and genotyping |
GB0321306D0 (en) | 2003-09-11 | 2003-10-15 | Solexa Ltd | Modified polymerases for improved incorporation of nucleotide analogues |
EP2789383B1 (en) | 2004-01-07 | 2023-05-03 | Illumina Cambridge Limited | Molecular arrays |
US20050227316A1 (en) * | 2004-04-07 | 2005-10-13 | Kosan Biosciences, Inc. | Synthetic genes |
JP2008513782A (en) | 2004-09-17 | 2008-05-01 | パシフィック バイオサイエンシーズ オブ カリフォルニア, インコーポレイテッド | Apparatus and method for molecular analysis |
WO2006064199A1 (en) | 2004-12-13 | 2006-06-22 | Solexa Limited | Improved method of nucleotide detection |
WO2007040592A1 (en) * | 2005-03-10 | 2007-04-12 | Gao, Xiaolian | Making nucleic acid sequences in parallel and use |
JP4990886B2 (en) | 2005-05-10 | 2012-08-01 | ソレックサ リミテッド | Improved polymerase |
DK1907571T3 (en) | 2005-06-15 | 2017-08-21 | Complete Genomics Inc | NUCLEIC ACID ANALYSIS USING INCIDENTAL MIXTURES OF NON-OVERLAPPING FRAGMENTS |
GB0514936D0 (en) | 2005-07-20 | 2005-08-24 | Solexa Ltd | Preparation of templates for nucleic acid sequencing |
EP1937400A4 (en) | 2005-09-14 | 2011-02-23 | Illumina Inc | Continuous polymer synthesizer |
US7405281B2 (en) | 2005-09-29 | 2008-07-29 | Pacific Biosciences Of California, Inc. | Fluorescent nucleotide analogs and uses therefor |
GB0522310D0 (en) | 2005-11-01 | 2005-12-07 | Solexa Ltd | Methods of preparing libraries of template polynucleotides |
US7329860B2 (en) | 2005-11-23 | 2008-02-12 | Illumina, Inc. | Confocal imaging methods and apparatus |
GB0524069D0 (en) * | 2005-11-25 | 2006-01-04 | Solexa Ltd | Preparation of templates for solid phase amplification |
EP2021503A1 (en) | 2006-03-17 | 2009-02-11 | Solexa Ltd. | Isothermal methods for creating clonal single molecule arrays |
EP3373174A1 (en) | 2006-03-31 | 2018-09-12 | Illumina, Inc. | Systems and devices for sequence by synthesis analysis |
WO2008054543A2 (en) * | 2006-05-20 | 2008-05-08 | Codon Devices, Inc. | Oligonucleotides for multiplex nucleic acid assembly |
AU2007309504B2 (en) | 2006-10-23 | 2012-09-13 | Pacific Biosciences Of California, Inc. | Polymerase enzymes and reagents for enhanced nucleic acid sequencing |
US7813013B2 (en) | 2006-11-21 | 2010-10-12 | Illumina, Inc. | Hexagonal site line scanning method and system |
US8039817B2 (en) | 2008-05-05 | 2011-10-18 | Illumina, Inc. | Compensator for multiple surface imaging |
EP2398915B1 (en) * | 2009-02-20 | 2016-08-24 | Synthetic Genomics, Inc. | Synthesis of sequence-verified nucleic acids |
WO2010127304A2 (en) | 2009-05-01 | 2010-11-04 | Illumina, Inc. | Sequencing methods |
CN102597256B (en) | 2009-08-25 | 2014-12-03 | 伊鲁米那股份有限公司 | Methods for selecting and amplifying polynucleotides |
US9309556B2 (en) * | 2010-09-24 | 2016-04-12 | The Board Of Trustees Of The Leland Stanford Junior University | Direct capture, amplification and sequencing of target DNA using immobilized primers |
US8759038B2 (en) | 2010-09-29 | 2014-06-24 | Illumina Cambridge Limited | Compositions and methods for sequencing nucleic acids |
US20140045728A1 (en) | 2010-10-22 | 2014-02-13 | President And Fellows Of Harvard College | Orthogonal Amplification and Assembly of Nucleic Acid Sequences |
US8951781B2 (en) | 2011-01-10 | 2015-02-10 | Illumina, Inc. | Systems, methods, and apparatuses to image a sample for biological or chemical analysis |
CN105973805B (en) * | 2011-01-10 | 2019-06-18 | 伊鲁米那股份有限公司 | The imaging method of sample for biological or chemical analysis |
WO2012170936A2 (en) | 2011-06-09 | 2012-12-13 | Illumina, Inc. | Patterned flow-cells useful for nucleic acid analysis |
EP2944693B1 (en) * | 2011-08-26 | 2019-04-24 | Gen9, Inc. | Compositions and methods for high fidelity assembly of nucleic acids |
HRP20211523T1 (en) * | 2011-09-23 | 2021-12-24 | Illumina, Inc. | Compositions for nucleic acid sequencing |
US8637242B2 (en) | 2011-11-07 | 2014-01-28 | Illumina, Inc. | Integrated sequencing apparatuses and methods of use |
WO2013151622A1 (en) | 2012-04-03 | 2013-10-10 | Illumina, Inc. | Integrated optoelectronic read head and fluidic cartridge useful for nucleic acid sequencing |
EP4001427A1 (en) * | 2012-04-24 | 2022-05-25 | Gen9, Inc. | Methods for sorting nucleic acids and multiplexed preparative in vitro cloning |
US9012022B2 (en) | 2012-06-08 | 2015-04-21 | Illumina, Inc. | Polymer coatings |
-
2015
- 2015-05-14 CA CA3219413A patent/CA3219413A1/en active Pending
- 2015-05-14 SG SG10201809312QA patent/SG10201809312QA/en unknown
- 2015-05-14 US US15/312,851 patent/US10570447B2/en active Active
- 2015-05-14 ES ES15729968T patent/ES2876432T3/en active Active
- 2015-05-14 CA CA2951118A patent/CA2951118C/en active Active
- 2015-05-14 EP EP15729968.6A patent/EP3143161B1/en active Active
- 2015-05-14 AU AU2015259024A patent/AU2015259024B2/en active Active
- 2015-05-14 WO PCT/US2015/030889 patent/WO2015175832A1/en active Application Filing
- 2015-05-14 SG SG11201610168YA patent/SG11201610168YA/en unknown
- 2015-05-14 DK DK15729968.6T patent/DK3143161T3/en active
- 2015-05-14 CN CN201580037498.1A patent/CN106536734B/en active Active
-
2019
- 2019-12-05 US US16/704,190 patent/US20200181699A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2015259024A1 (en) | 2016-12-22 |
US20170191126A1 (en) | 2017-07-06 |
WO2015175832A1 (en) | 2015-11-19 |
CA2951118A1 (en) | 2015-11-19 |
ES2876432T3 (en) | 2021-11-12 |
EP3143161A1 (en) | 2017-03-22 |
AU2015259024B2 (en) | 2021-07-01 |
CN106536734A (en) | 2017-03-22 |
CN106536734B (en) | 2020-12-22 |
DK3143161T3 (en) | 2021-06-21 |
SG11201610168YA (en) | 2017-01-27 |
US10570447B2 (en) | 2020-02-25 |
US20200181699A1 (en) | 2020-06-11 |
CA2951118C (en) | 2024-01-09 |
EP3143161B1 (en) | 2021-04-21 |
CA3219413A1 (en) | 2015-11-19 |
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