SG10201801161PA - A system for adaptive control of medicament delivery, and related process - Google Patents

A system for adaptive control of medicament delivery, and related process

Info

Publication number
SG10201801161PA
SG10201801161PA SG10201801161PA SG10201801161PA SG10201801161PA SG 10201801161P A SG10201801161P A SG 10201801161PA SG 10201801161P A SG10201801161P A SG 10201801161PA SG 10201801161P A SG10201801161P A SG 10201801161PA SG 10201801161P A SG10201801161P A SG 10201801161PA
Authority
SG
Singapore
Prior art keywords
medicament
dose
administration
subject
measurements
Prior art date
Application number
SG10201801161PA
Inventor
Ban Leong Sng
Alex Tiong Heng Sia
Tan Hong Chun Gabriel
Original Assignee
Singapore Health Serv Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Singapore Health Serv Pte Ltd filed Critical Singapore Health Serv Pte Ltd
Priority to SG10201801161PA priority Critical patent/SG10201801161PA/en
Priority to PCT/SG2019/050080 priority patent/WO2019156639A1/en
Publication of SG10201801161PA publication Critical patent/SG10201801161PA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G16H20/17—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/0816—Measuring devices for examining respiratory frequency
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/083—Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
    • A61B5/0836—Measuring rate of CO2 production
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14542—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring blood gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M2005/14208—Pressure infusion, e.g. using pumps with a programmable infusion control system, characterised by the infusion program
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A61M2205/52—General characteristics of the apparatus with microprocessors or computers with memories providing a history of measured variating parameters of apparatus or patient

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medical Informatics (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Primary Health Care (AREA)
  • Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

Described herein is a computer system for adaptive control of medicament availability. The system comprises at least one processor, a counter, a medicament controller, at least one parameter sensor, a threshold comparator, and at least one memory. The memory stores instructions that, when executed by the processor(s), cause the system to make a first dose of a medicament available for administration to a subject using the medicament controller. The instructions, when executed by the processor(s), further cause the system to take measurements of one or more parameters of the subject using the parameter sensor(s), the one or more parameters being subject to change in response to administration of the medicament, once the first dose is administered to the subject, and determine, using the threshold comparator, if at least one of the measurements exceeds a relevant predetermined threshold. The instructions, when executed by the processor(s), further cause the system to make a second dose of the medicament available for administration to the subject, using the medicament controller, only after expiry of a first predetermined time period from administration of the first dose, the first predetermined time period being set by the counter, if none of the measurements exceed the relevant predetermined threshold. And, if one or more of the measurements exceeds the relevant predetermined threshold, the instructions, when executed by the processor(s), cause the system to take successive further measurements of the one or more parameters using the parameter sensor(s), and once the further measurements no longer exceed the relevant predetermined threshold, make the second dose of the medicament available for administration to the subject, using the medicament controller, only after expiry of a second predetermined time period from administration of the first dose, the second predetermined time period being set by the counter. [FIG. 3]
SG10201801161PA 2018-02-12 2018-02-12 A system for adaptive control of medicament delivery, and related process SG10201801161PA (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
SG10201801161PA SG10201801161PA (en) 2018-02-12 2018-02-12 A system for adaptive control of medicament delivery, and related process
PCT/SG2019/050080 WO2019156639A1 (en) 2018-02-12 2019-02-12 A system for adaptive control of medicament delivery, and related process

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SG10201801161PA SG10201801161PA (en) 2018-02-12 2018-02-12 A system for adaptive control of medicament delivery, and related process

Publications (1)

Publication Number Publication Date
SG10201801161PA true SG10201801161PA (en) 2019-09-27

Family

ID=67549178

Family Applications (1)

Application Number Title Priority Date Filing Date
SG10201801161PA SG10201801161PA (en) 2018-02-12 2018-02-12 A system for adaptive control of medicament delivery, and related process

Country Status (2)

Country Link
SG (1) SG10201801161PA (en)
WO (1) WO2019156639A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113842521B (en) * 2021-09-24 2022-08-02 杭州兰马医疗科技有限公司 Infusion device and control method thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5507277A (en) * 1993-01-29 1996-04-16 Aradigm Corporation Lockout device for controlled release of drug from patient-activateddispenser
WO2005056087A1 (en) * 2003-12-05 2005-06-23 Cardinal Health 303, Inc. Patient-controlled analgesia with patient monitoring system
US8357114B2 (en) * 2006-01-06 2013-01-22 Acelrx Pharmaceuticals, Inc. Drug dispensing device with flexible push rod
US9724469B2 (en) * 2011-03-24 2017-08-08 Singapore Health Services Pte. Ltd. Method and a system for controlling discomfort level

Also Published As

Publication number Publication date
WO2019156639A1 (en) 2019-08-15

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