SG10201704611WA - Compositions comprising cyclic purine dinucleotides having defined stereochemistries and methods for their preparation and use - Google Patents
Compositions comprising cyclic purine dinucleotides having defined stereochemistries and methods for their preparation and useInfo
- Publication number
- SG10201704611WA SG10201704611WA SG10201704611WA SG10201704611WA SG10201704611WA SG 10201704611W A SG10201704611W A SG 10201704611WA SG 10201704611W A SG10201704611W A SG 10201704611WA SG 10201704611W A SG10201704611W A SG 10201704611WA SG 10201704611W A SG10201704611W A SG 10201704611WA
- Authority
- SG
- Singapore
- Prior art keywords
- compositions
- preparation
- methods
- cyclic purine
- purine dinucleotides
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
- C07H19/213—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids containing cyclic phosphate
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Virology (AREA)
- Hematology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261737006P | 2012-12-13 | 2012-12-13 | |
| US201361790514P | 2013-03-15 | 2013-03-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201704611WA true SG10201704611WA (en) | 2017-07-28 |
Family
ID=50935019
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201502796RA SG11201502796RA (en) | 2012-12-13 | 2013-12-13 | Compositions comprising cyclic purine dinucleotides having defined stereochemistries and methods for their preparation and use |
| SG10201704611WA SG10201704611WA (en) | 2012-12-13 | 2013-12-13 | Compositions comprising cyclic purine dinucleotides having defined stereochemistries and methods for their preparation and use |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201502796RA SG11201502796RA (en) | 2012-12-13 | 2013-12-13 | Compositions comprising cyclic purine dinucleotides having defined stereochemistries and methods for their preparation and use |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US9695212B2 (en) |
| EP (2) | EP3527579A1 (en) |
| JP (2) | JP6333843B2 (en) |
| KR (1) | KR20150095668A (en) |
| CN (2) | CN105008381B (en) |
| AU (2) | AU2013358892B2 (en) |
| BR (1) | BR112015013440B1 (en) |
| CA (1) | CA2886456A1 (en) |
| DK (1) | DK2931738T3 (en) |
| EA (1) | EA201590396A1 (en) |
| ES (1) | ES2718910T3 (en) |
| HK (1) | HK1212707A1 (en) |
| HU (1) | HUE043262T2 (en) |
| MX (1) | MX361680B (en) |
| PL (1) | PL2931738T3 (en) |
| PT (1) | PT2931738T (en) |
| SG (2) | SG11201502796RA (en) |
| SI (1) | SI2931738T1 (en) |
| WO (1) | WO2014093936A1 (en) |
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| ES2773858T3 (en) | 2010-10-06 | 2020-07-15 | Harvard College | Injectable Pore Forming Hydrogels for Cellular Therapies Based on Materials |
| EP2858722B8 (en) * | 2012-06-08 | 2018-02-21 | Aduro BioTech, Inc. | Compostions and methods for cancer immunotherapy |
| HUE043262T2 (en) | 2012-12-13 | 2019-08-28 | Aduro Biotech Inc | Compositions comprising cyclic purine dinucleotides having defined stereochemistries and methods for their preparation and use |
| EP3398616A3 (en) | 2012-12-19 | 2019-01-30 | Board of Regents, The University of Texas System | Pharmaceutical targeting of a mammalian cyclic di-nucleotide signaling pathway |
| EA201592074A1 (en) | 2013-04-29 | 2016-02-29 | Мемориал Слоан Кеттеринг Кэнсер Сентер | COMPOSITIONS AND METHODS OF CHANGING THE SIGNAL SYSTEM OF THE SECONDARY MESSENGER |
| ES2822584T3 (en) * | 2013-05-03 | 2021-05-04 | Univ California | Induction of cyclic dinucleotides of type I interferon |
| US9549944B2 (en) | 2013-05-18 | 2017-01-24 | Aduro Biotech, Inc. | Compositions and methods for inhibiting “stimulator of interferon gene”—dependent signalling |
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| US11571462B2 (en) | 2015-06-03 | 2023-02-07 | The Medical College Of Wisconsin, Inc. | Engineered CCL20 locked dimer polypeptide |
| US10738095B2 (en) | 2015-06-03 | 2020-08-11 | The Medical College Of Wisconsin, Inc. | Engineered CCL20 locked dimer polypeptide |
| TWI696629B (en) | 2015-08-13 | 2020-06-21 | 美商默沙東藥廠 | Cyclic di-nucleotide compounds as sting agonists |
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- 2013-12-13 US US14/106,687 patent/US9695212B2/en active Active
- 2013-12-13 CN CN201810801443.9A patent/CN108542913A/en active Pending
- 2013-12-13 MX MX2015007447A patent/MX361680B/en active IP Right Grant
- 2013-12-13 DK DK13863379.7T patent/DK2931738T3/en active
- 2013-12-13 WO PCT/US2013/075189 patent/WO2014093936A1/en active Application Filing
- 2013-12-13 EA EA201590396A patent/EA201590396A1/en unknown
- 2013-12-13 ES ES13863379T patent/ES2718910T3/en active Active
-
2016
- 2016-01-21 HK HK16100666.5A patent/HK1212707A1/en not_active IP Right Cessation
-
2017
- 2017-06-22 US US15/630,741 patent/US10414789B2/en active Active
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2018
- 2018-04-25 JP JP2018084405A patent/JP6704012B2/en active Active
- 2018-05-25 AU AU2018203682A patent/AU2018203682B2/en not_active Ceased
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