SG10201703965SA - Compositions and methods for treating and preventing staphylococcus aureus infections - Google Patents

Compositions and methods for treating and preventing staphylococcus aureus infections

Info

Publication number
SG10201703965SA
SG10201703965SA SG10201703965SA SG10201703965SA SG10201703965SA SG 10201703965S A SG10201703965S A SG 10201703965SA SG 10201703965S A SG10201703965S A SG 10201703965SA SG 10201703965S A SG10201703965S A SG 10201703965SA SG 10201703965S A SG10201703965S A SG 10201703965SA
Authority
SG
Singapore
Prior art keywords
compositions
treating
methods
staphylococcus aureus
aureus infections
Prior art date
Application number
SG10201703965SA
Inventor
John Simard
Original Assignee
Xbiotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xbiotech Inc filed Critical Xbiotech Inc
Publication of SG10201703965SA publication Critical patent/SG10201703965SA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1271Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/14Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/085Staphylococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/40Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum bacterial
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732Antibody-dependent cellular cytotoxicity [ADCC]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SG10201703965SA 2014-06-03 2015-06-03 Compositions and methods for treating and preventing staphylococcus aureus infections SG10201703965SA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462007242P 2014-06-03 2014-06-03
US201462041423P 2014-08-25 2014-08-25
US201562115665P 2015-02-13 2015-02-13

Publications (1)

Publication Number Publication Date
SG10201703965SA true SG10201703965SA (en) 2017-06-29

Family

ID=54700993

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201703965SA SG10201703965SA (en) 2014-06-03 2015-06-03 Compositions and methods for treating and preventing staphylococcus aureus infections
SG11201609487QA SG11201609487QA (en) 2014-06-03 2015-06-03 Compositions and methods for treating and preventing staphylococcus aureus infections

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201609487QA SG11201609487QA (en) 2014-06-03 2015-06-03 Compositions and methods for treating and preventing staphylococcus aureus infections

Country Status (19)

Country Link
US (7) US9416172B2 (en)
EP (2) EP3970747A3 (en)
JP (4) JP6166000B1 (en)
KR (4) KR102015451B1 (en)
CN (2) CN106456763B (en)
AU (2) AU2015271749B2 (en)
BR (1) BR112016028043B1 (en)
CA (1) CA2950840C (en)
CL (1) CL2016003071A1 (en)
ES (1) ES2894867T3 (en)
IL (1) IL248959B (en)
MX (1) MX355107B (en)
MY (1) MY191346A (en)
NZ (1) NZ726911A (en)
PH (2) PH12016502372B1 (en)
RU (2) RU2764981C1 (en)
SG (2) SG10201703965SA (en)
WO (1) WO2015187779A1 (en)
ZA (1) ZA201608604B (en)

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Also Published As

Publication number Publication date
EP3154584A4 (en) 2018-06-06
US20200131252A1 (en) 2020-04-30
CN108404128A (en) 2018-08-17
EP3970747A2 (en) 2022-03-23
US20190127449A1 (en) 2019-05-02
KR20170007825A (en) 2017-01-20
AU2018200886B2 (en) 2019-06-06
BR112016028043B1 (en) 2023-12-12
JP2017522275A (en) 2017-08-10
KR20170078846A (en) 2017-07-07
KR20190100471A (en) 2019-08-28
AU2018200886A1 (en) 2018-02-22
US20150344548A1 (en) 2015-12-03
CN106456763B (en) 2018-03-13
JP6672221B2 (en) 2020-03-25
MX355107B (en) 2018-04-04
US9486523B2 (en) 2016-11-08
EP3970747A3 (en) 2022-10-05
RU2636780C1 (en) 2017-11-28
PH12016502372A1 (en) 2017-02-20
WO2015187779A1 (en) 2015-12-10
US9783598B2 (en) 2017-10-10
US20220251175A1 (en) 2022-08-11
US9416172B2 (en) 2016-08-16
KR20210047355A (en) 2021-04-29
US20170349648A1 (en) 2017-12-07
US20160279243A1 (en) 2016-09-29
US11773157B2 (en) 2023-10-03
KR101753553B1 (en) 2017-07-03
MY191346A (en) 2022-06-17
JP6166000B1 (en) 2017-07-19
JP2022105178A (en) 2022-07-12
AU2015271749A1 (en) 2016-12-01
JP2020073548A (en) 2020-05-14
ES2894867T3 (en) 2022-02-16
KR102015451B1 (en) 2019-08-28
CN106456763A (en) 2017-02-22
CA2950840C (en) 2023-09-26
JP2017214388A (en) 2017-12-07
PH12018501429A1 (en) 2019-02-27
US10214581B2 (en) 2019-02-26
EP3154584B1 (en) 2021-08-04
ZA201608604B (en) 2018-05-30
IL248959B (en) 2022-01-01
AU2015271749B2 (en) 2018-03-01
US11370831B2 (en) 2022-06-28
US20170015734A1 (en) 2017-01-19
MX2016015812A (en) 2017-04-25
IL248959A0 (en) 2017-01-31
US10577410B2 (en) 2020-03-03
NZ726911A (en) 2023-01-27
BR112016028043A2 (en) 2017-10-24
SG11201609487QA (en) 2016-12-29
PH12016502372B1 (en) 2017-02-20
CL2016003071A1 (en) 2017-09-15
EP3154584A1 (en) 2017-04-19
RU2764981C1 (en) 2022-01-24
CA2950840A1 (en) 2015-12-10

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