SG10201602384VA - Perfluorinated compounds for the non-viral transfer of nucleic acids - Google Patents
Perfluorinated compounds for the non-viral transfer of nucleic acidsInfo
- Publication number
- SG10201602384VA SG10201602384VA SG10201602384VA SG10201602384VA SG10201602384VA SG 10201602384V A SG10201602384V A SG 10201602384VA SG 10201602384V A SG10201602384V A SG 10201602384VA SG 10201602384V A SG10201602384V A SG 10201602384VA SG 10201602384V A SG10201602384V A SG 10201602384VA
- Authority
- SG
- Singapore
- Prior art keywords
- nucleic acids
- viral transfer
- perfluorinated compounds
- perfluorinated
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/52—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an inorganic compound, e.g. an inorganic ion that is complexed with the active ingredient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Inorganic Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102011016334 | 2011-03-31 | ||
DE102011101361 | 2011-05-09 | ||
DE102011112191 | 2011-08-26 | ||
DE102011117390 | 2011-10-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201602384VA true SG10201602384VA (en) | 2016-05-30 |
Family
ID=45974266
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10202010626PA SG10202010626PA (en) | 2011-03-31 | 2012-03-29 | Perfluorinated compounds for the non-viral transfer of nucleic acids |
SG10201602384VA SG10201602384VA (en) | 2011-03-31 | 2012-03-29 | Perfluorinated compounds for the non-viral transfer of nucleic acids |
SG2013073242A SG194013A1 (en) | 2011-03-31 | 2012-03-29 | Perfluorinated compounds for the non-viral transfer of nucleic acids |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10202010626PA SG10202010626PA (en) | 2011-03-31 | 2012-03-29 | Perfluorinated compounds for the non-viral transfer of nucleic acids |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG2013073242A SG194013A1 (en) | 2011-03-31 | 2012-03-29 | Perfluorinated compounds for the non-viral transfer of nucleic acids |
Country Status (8)
Country | Link |
---|---|
US (2) | US20140065223A1 (en) |
EP (1) | EP2691118B1 (en) |
JP (1) | JP2014510743A (en) |
CN (1) | CN103764169B (en) |
AU (1) | AU2012234259A1 (en) |
CA (1) | CA2830324A1 (en) |
SG (3) | SG10202010626PA (en) |
WO (1) | WO2012130941A2 (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9303079B2 (en) | 2012-04-02 | 2016-04-05 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
AU2013243953A1 (en) | 2012-04-02 | 2014-10-30 | Modernatx, Inc. | Modified polynucleotides for the production of nuclear proteins |
US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
US9136377B2 (en) * | 2013-03-11 | 2015-09-15 | Alpha & Omega Semiconductor, Inc. | High density MOSFET array with self-aligned contacts delimited by nitride-capped trench gate stacks and method |
WO2017186711A1 (en) | 2016-04-25 | 2017-11-02 | Invivogen | Novel complexes of immunostimulatory compounds, and uses thereof |
CN106187981B (en) * | 2016-07-11 | 2018-04-03 | 中国科学院生态环境研究中心 | A kind of perfluoroalkyl acid probe of fluorescence labeling and its application |
WO2019042888A1 (en) * | 2017-08-27 | 2019-03-07 | Caperis Gmbh | Perfluorinated nucleic acids used as surfactants with specific properties |
CN113924309A (en) * | 2019-05-21 | 2022-01-11 | 株式会社纳蒂亚斯 | Polyfluoro block polymers for use in oligonucleotide synthesis and methods of oligonucleotide synthesis using same |
JPWO2021060506A1 (en) * | 2019-09-27 | 2021-04-01 | ||
WO2022186350A1 (en) | 2021-03-03 | 2022-09-09 | 国立大学法人東京大学 | Acyclic threoninol nucleic acid |
CN114933565A (en) * | 2022-05-12 | 2022-08-23 | 深圳厚存纳米药业有限公司 | Nucleobase derivative nanoparticles and composition thereof |
CN115368575B (en) * | 2022-10-25 | 2023-01-13 | 山东华夏神舟新材料有限公司 | Water-repellent and oil-repellent fabric finishing agent, finishing agent stock solution and preparation method thereof |
Family Cites Families (38)
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JPS5663966A (en) * | 1979-10-29 | 1981-05-30 | Tokyo Kinzoku Kogyo Kk | Pyrimidine derivative and its preparation |
JPS63188696A (en) * | 1987-01-29 | 1988-08-04 | Sumitomo Chem Co Ltd | Production of 5-(perfluoroalkyl)uridine derivative |
FR2640629B1 (en) * | 1988-12-20 | 1991-02-08 | Merieux Inst | NOVEL DEOXY-2 RIBONUCLEOSIDES DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATIONS |
US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
US6214804B1 (en) | 1989-03-21 | 2001-04-10 | Vical Incorporated | Induction of a protective immune response in a mammal by injecting a DNA sequence |
JPH04117366A (en) * | 1990-09-06 | 1992-04-17 | Nippon Oil & Fats Co Ltd | Polyfluoroalkyl group-containing pyrimidine derivative and production thereof |
JP3032781B2 (en) * | 1990-09-06 | 2000-04-17 | 工業技術院長 | Method for producing pyrimidine derivative containing fluoroalkyl group |
JPH04352769A (en) * | 1990-09-12 | 1992-12-07 | Nippon Oil & Fats Co Ltd | Fluoroalkyl group-containing uracil derivative and production thereof |
JPH04149193A (en) * | 1990-10-15 | 1992-05-22 | Nippon Oil & Fats Co Ltd | Fluoroalkyl-containing uridine derivative and its production |
JP3047077B2 (en) * | 1990-10-15 | 2000-05-29 | 工業技術院長 | Method for producing fluoroalkyl group-containing uridine derivative |
JPH04257565A (en) * | 1991-02-08 | 1992-09-11 | Nippon Oil & Fats Co Ltd | Polyfluoroalkyl group-containing pyrimidine derivative and its production |
JP3032837B2 (en) * | 1991-02-14 | 2000-04-17 | 工業技術院長 | Fluoroalkyl group-containing pyrimidine derivative and method for producing the same |
JP3086912B2 (en) * | 1991-06-20 | 2000-09-11 | 工業技術院長 | Fluoroalkyl group-containing purine derivative and method for producing the same |
HUP9900879A2 (en) * | 1995-06-07 | 1999-08-30 | Alliance Pharmaceutical Corp. | Reverse fluorocarbon emulsion compositions for drug delivery |
EP2292771A3 (en) | 1997-09-19 | 2011-07-27 | Life Technologies Corporation | Sense mRNA therapy |
JP4160645B2 (en) * | 1997-12-24 | 2008-10-01 | 大日本住友製薬株式会社 | Novel adenine derivatives and their pharmaceutical use |
JP4162840B2 (en) * | 1999-08-20 | 2008-10-08 | セケラ インコーポレイテッド | New A-50039 derivative |
JP4658438B2 (en) * | 2001-02-19 | 2011-03-23 | セケラ インコーポレイテッド | Antibacterial agent containing novel A-50039 derivative |
EP2305699B1 (en) | 2001-06-05 | 2014-08-13 | CureVac GmbH | Stabilised mRNA with increased G/C content which is optimised for translation in its coded areas for the vaccination against sleeping sickness, leishmaniosis and toxoplasmosis |
JP2003116581A (en) * | 2001-10-18 | 2003-04-22 | Dna Chip Kenkyusho:Kk | Labeled nucleic acid and method for producing the same |
WO2003062198A1 (en) * | 2002-01-24 | 2003-07-31 | Barnes Jewish Hospital | Integrin targeted imaging agents |
NZ536123A (en) * | 2002-05-06 | 2006-09-29 | Genelabs Tech Inc | Nucleoside derivatives for treating hepatitis C virus infection |
FR2846969A1 (en) * | 2002-11-08 | 2004-05-14 | Salles Jean Pierre | New modified active agent derivatives with improved bioavailability comprising parent drug, e.g. anticancer agent, plus fluorinated hydrocarbon chain and recognition or hydrophilizing moiety |
JP4945129B2 (en) * | 2004-01-27 | 2012-06-06 | 株式会社キラルジェン | Fluorous carrier and method for producing oligonucleotide derivative using the same |
FR2869616B1 (en) * | 2004-04-29 | 2008-10-24 | Univ D Avignon Et Des Pays Du | NOVEL AMPHIPHILIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATIONS IN PARTICULAR FOR TRANSFECTION |
US20060178507A1 (en) * | 2004-12-30 | 2006-08-10 | Berry & Associates, Inc. | Fluorous oligonucleotide reagents and affinity purification of oligonucleotides |
JP5053622B2 (en) * | 2005-11-09 | 2012-10-17 | 東ソー株式会社 | Nucleobase having a perfluoroalkyl group and method for producing the same |
JP5320284B2 (en) * | 2006-05-03 | 2013-10-23 | キメリクス,インコーポレーテッド | Metabolically stable alkoxyalkyl esters of antiviral or antiproliferative phosphonates, nucleoside phosphonates and nucleoside phosphates |
US20100016409A1 (en) | 2006-06-02 | 2010-01-21 | Government Of The Us, As Represented By The Secretary, Department Of Health And Human Services | Rna Nanoparticles and Nanotubes |
CA2654375A1 (en) * | 2006-06-27 | 2008-01-03 | Biovitrum Ab (Publ) | Therapeutic compounds |
JP5090711B2 (en) * | 2006-11-06 | 2012-12-05 | 東ソー株式会社 | Process for producing 2,6-diamino-8,8-bis (perfluoroalkyl) -8H-purines |
EP2170888B1 (en) * | 2007-06-29 | 2015-04-22 | Gilead Sciences, Inc. | Purine derivatives and their use as modulators of toll-like receptor 7 |
TWI437994B (en) * | 2007-09-17 | 2014-05-21 | Abbvie Bahamas Ltd | Anti-infective agents and uses thereof |
EP2123256A1 (en) * | 2008-05-19 | 2009-11-25 | Ruhr-Universität Bochum | Perfluorcarbon nanoemulsions with endocytosis enhancing surface for gene-transfer |
CA2726579C (en) * | 2008-06-03 | 2015-02-17 | Taiho Pharmaceutical Co., Ltd. | Novel uracil compound or salt thereof having human deoxyuridine triphosphatase inhibitory activity |
GB0813042D0 (en) * | 2008-07-16 | 2008-08-20 | Syngenta Participations Ag | Insecticidal compounds |
CN102762698B (en) * | 2010-02-18 | 2014-10-22 | 国际壳牌研究有限公司 | Tubular wall assembly and gasification reactor |
US8895737B2 (en) * | 2010-07-16 | 2014-11-25 | Shashank Shekhar | Process for preparing antiviral compounds |
-
2012
- 2012-03-29 SG SG10202010626PA patent/SG10202010626PA/en unknown
- 2012-03-29 WO PCT/EP2012/055639 patent/WO2012130941A2/en active Application Filing
- 2012-03-29 SG SG10201602384VA patent/SG10201602384VA/en unknown
- 2012-03-29 US US14/008,950 patent/US20140065223A1/en not_active Abandoned
- 2012-03-29 AU AU2012234259A patent/AU2012234259A1/en not_active Abandoned
- 2012-03-29 EP EP12714607.4A patent/EP2691118B1/en active Active
- 2012-03-29 SG SG2013073242A patent/SG194013A1/en unknown
- 2012-03-29 JP JP2014501619A patent/JP2014510743A/en active Pending
- 2012-03-29 CN CN201280021274.8A patent/CN103764169B/en not_active Expired - Fee Related
- 2012-03-29 CA CA2830324A patent/CA2830324A1/en not_active Abandoned
-
2019
- 2019-05-15 US US16/413,513 patent/US20190382790A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2012130941A2 (en) | 2012-10-04 |
US20190382790A1 (en) | 2019-12-19 |
CN103764169B (en) | 2017-06-13 |
EP2691118A2 (en) | 2014-02-05 |
CA2830324A1 (en) | 2012-10-04 |
JP2014510743A (en) | 2014-05-01 |
WO2012130941A3 (en) | 2013-01-03 |
AU2012234259A1 (en) | 2013-10-03 |
SG10202010626PA (en) | 2020-11-27 |
CN103764169A (en) | 2014-04-30 |
SG194013A1 (en) | 2013-11-29 |
US20140065223A1 (en) | 2014-03-06 |
EP2691118B1 (en) | 2019-05-01 |
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