SG10201501980SA - Homogeneous suspension of immunopotentiating compounds and uses thereof - Google Patents
Homogeneous suspension of immunopotentiating compounds and uses thereofInfo
- Publication number
- SG10201501980SA SG10201501980SA SG10201501980SA SG10201501980SA SG10201501980SA SG 10201501980S A SG10201501980S A SG 10201501980SA SG 10201501980S A SG10201501980S A SG 10201501980SA SG 10201501980S A SG10201501980S A SG 10201501980SA SG 10201501980S A SG10201501980S A SG 10201501980SA
- Authority
- SG
- Singapore
- Prior art keywords
- homogeneous suspension
- immunopotentiating compounds
- immunopotentiating
- compounds
- homogeneous
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 230000002434 immunopotentiative effect Effects 0.000 title 1
- 239000000725 suspension Substances 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
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- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
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- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
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- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
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- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/14011—Filoviridae
- C12N2760/14111—Ebolavirus, e.g. Zaire ebolavirus
- C12N2760/14134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28675409P | 2009-12-15 | 2009-12-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201501980SA true SG10201501980SA (en) | 2015-05-28 |
Family
ID=43920779
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201501980SA SG10201501980SA (en) | 2009-12-15 | 2010-12-15 | Homogeneous suspension of immunopotentiating compounds and uses thereof |
SG2012044012A SG181712A1 (en) | 2009-12-15 | 2010-12-15 | Homogeneous suspension of immunopotentiating compounds and uses thereof |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG2012044012A SG181712A1 (en) | 2009-12-15 | 2010-12-15 | Homogeneous suspension of immunopotentiating compounds and uses thereof |
Country Status (11)
Country | Link |
---|---|
US (2) | US9408907B2 (en) |
EP (1) | EP2512478B1 (en) |
JP (2) | JP5814933B2 (en) |
CN (1) | CN102762206A (en) |
AU (1) | AU2010339921B2 (en) |
BR (1) | BR112012014624A8 (en) |
CA (1) | CA2784580A1 (en) |
ES (1) | ES2631977T3 (en) |
MX (1) | MX339146B (en) |
SG (2) | SG10201501980SA (en) |
WO (1) | WO2011084549A1 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2502631A1 (en) * | 2011-03-22 | 2012-09-26 | Medizinische Hochschule Hannover | Immune suppressor and its use |
MX2015005306A (en) * | 2012-10-25 | 2015-07-17 | Glaxosmithkline Biolog Sa | Nicotinamide as adjuvant. |
CN103784966B (en) * | 2014-01-23 | 2016-03-23 | 广东省农业科学院动物卫生研究所 | The application of sodium carboxymethyl cellulose in E.tenella oocysts vaccine |
EP3061826A1 (en) | 2015-02-27 | 2016-08-31 | Novartis AG | Flavivirus replicons |
JP7378931B2 (en) * | 2015-11-03 | 2023-11-14 | エイシー イミューン ソシエテ アノニム | Vaccination methods against self-antigens in human patients |
CN106045902A (en) * | 2016-06-30 | 2016-10-26 | 苏州健雄职业技术学院 | Preparation method of 3-bromo-6-methyl-2-pyridylaldehyde |
GB202215414D0 (en) * | 2022-10-18 | 2022-11-30 | Glaxosmithkline Biologicals Sa | Vaccine |
Family Cites Families (85)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2848965A1 (en) | 1978-11-11 | 1980-05-22 | Behringwerke Ag | METHOD FOR PRODUCING MEMBRANE PROTEINS FROM NEISSERIA MENINGITIDIS AND VACCINE CONTAINING THEM |
US4726912A (en) * | 1986-08-27 | 1988-02-23 | Phillips Petroleum Company | Stable suspensions of carboxymethyl cellulose and their preparation |
US5428040A (en) * | 1993-08-31 | 1995-06-27 | The Du Pont Merck Pharmaceutical Company | Carbocyclic fused-ring quinolinecarboxylic acids useful as immunosuppressive agents |
IL117483A (en) | 1995-03-17 | 2008-03-20 | Bernard Brodeur | Proteinase k resistant surface protein of neisseria meningitidis |
US6180111B1 (en) | 1995-05-18 | 2001-01-30 | University Of Maryland | Vaccine delivery system |
JP2000511769A (en) | 1996-04-02 | 2000-09-12 | スミスクライン・ビーチャム・コーポレイション | New compound |
JP2000508178A (en) | 1996-05-14 | 2000-07-04 | スミスクライン・ビーチャム・コーポレイション | New compound |
PT942983E (en) | 1996-10-31 | 2007-02-28 | Human Genome Sciences Inc | Streptococcus pneumoniae antigens and vaccines |
GB9711964D0 (en) | 1997-06-09 | 1997-08-06 | Medical Res Council | Live attenuated vaccines |
US6800744B1 (en) | 1997-07-02 | 2004-10-05 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics |
US7011836B1 (en) | 1997-08-21 | 2006-03-14 | De Staat Der Nederlanden, Vertenwoordigd Door De Minister Van Welzijn, Volksgezondheil En Cultuur | Mutants of gram negative mucosal bacteria and application thereof in vaccines |
WO1999024578A2 (en) | 1997-11-06 | 1999-05-20 | Chiron S.P.A. | Neisserial antigens |
JP4486748B2 (en) | 1997-11-26 | 2010-06-23 | インヒビテツクス,インコーポレイテツド | Extracellular matrix binding protein from Staphylococcus aureus |
CA2317815A1 (en) | 1998-01-14 | 1999-07-22 | Chiron S.P.A. | Neisseria meningitidis antigens |
AU770378B2 (en) | 1998-04-23 | 2004-02-19 | Uab Research Foundation | Pneumococcal surface protein C(PspC), epitopic regions and strain selection thereof, and uses therefor |
EP2261339B1 (en) | 1998-05-01 | 2017-03-22 | GlaxoSmithKline Biologicals SA | Neisseria meningitidis antigens and compositions |
GB9810193D0 (en) | 1998-05-12 | 1998-07-08 | Smithkline Beecham Biolog | Novel compounds |
DE69935986D1 (en) | 1998-07-27 | 2007-06-14 | Sanofi Pasteur Ltd | STREPTOCOCCUS PNEUMONIAE PROTEINS AND NUCLEIC ACIDS |
WO2000006738A2 (en) | 1998-07-27 | 2000-02-10 | Microbial Technics Limited | NUCLEIC ACIDS AND PROTEINS FROM $i(STREPTOCOCCUS PNEUMONIAE) |
ATE422368T1 (en) | 1998-08-31 | 2009-02-15 | Inhibitex Inc | MULTI-COMPONENT VACCINES AGAINST STAPHYLOCOCCUS AUREUS |
US6635473B1 (en) | 1998-08-31 | 2003-10-21 | The Provost Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin | Polypeptides and polynucleotides from coagulase-negative staphylococci |
WO2000022430A2 (en) | 1998-10-09 | 2000-04-20 | Chiron Corporation | Neisseria genomic sequences and methods of their use |
GB9823978D0 (en) | 1998-11-02 | 1998-12-30 | Microbiological Res Authority | Multicomponent meningococcal vaccine |
GB9828000D0 (en) | 1998-12-18 | 1999-02-10 | Chiron Spa | Antigens |
EP2050464B1 (en) | 1998-12-21 | 2019-08-07 | Medimmune, Inc. | Streptococcus pneumoniae proteins and immunogenic fragments for vaccines |
EP1165795A2 (en) | 1999-03-26 | 2002-01-02 | Provalis UK Limited | Streptococcus pneumoniae antigens |
ES2264419T3 (en) | 1999-06-10 | 2007-01-01 | Medimmune, Inc. | STREPTOCOCCUS PNEUMONIAE VACCINES AND PROTEINS. |
GB9918319D0 (en) | 1999-08-03 | 1999-10-06 | Smithkline Beecham Biolog | Vaccine composition |
EP1075841A1 (en) | 1999-08-13 | 2001-02-14 | Erasmus Universiteit Rotterdam | Pneumococcal vaccines |
AU1917501A (en) | 1999-11-12 | 2001-06-06 | University Of Iowa Research Foundation, The | Control of neisserial membrane synthesis |
PT1248647E (en) | 2000-01-17 | 2010-11-18 | Novartis Vaccines & Diagnostics Srl | Outer membrane vesicle (omv) vaccine comprising n. meningitidis serogroup b outer membrane proteins |
JP4846160B2 (en) | 2000-02-28 | 2011-12-28 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル | Hybrid expression of Neisseria proteins |
KR20020097200A (en) | 2000-03-21 | 2002-12-31 | 엘리트라 파마슈티컬즈, 인코포레이티드 | Identification of essential genes in prokaryotes |
EP1278856A2 (en) | 2000-04-27 | 2003-01-29 | Medimmune, Inc. | Immunogenic pneumococcal protein and vaccine compositions thereof |
NO20002828D0 (en) | 2000-06-02 | 2000-06-02 | Statens Inst For Folkehelse | Proteinaceous vaccine against Neisseria meningtidis serogroup and method of preparation thereof |
US6495079B1 (en) | 2000-06-28 | 2002-12-17 | Prisma Fibers, Inc. | Process to prepare polymeric fibers with improved color and appearance |
CA2414884A1 (en) | 2000-07-03 | 2002-01-10 | Chiron S.P.A. | Immunisation against chlamydia pneumoniae |
AU2001287645A1 (en) | 2000-07-20 | 2002-02-05 | Hansa Medical Ab | Fh-binding protein of streptococcus pneumiae |
ES2519440T3 (en) | 2000-07-27 | 2014-11-07 | Children's Hospital & Research Center At Oakland | Vaccines for broad spectrum protection against diseases caused by Neisseria meningitidis |
GB0103170D0 (en) | 2001-02-08 | 2001-03-28 | Smithkline Beecham Biolog | Vaccine composition |
AU8743001A (en) | 2000-08-28 | 2002-03-13 | Aventis Pasteur | Moraxella polypeptides and corresponding dna fragments and uses thereof |
GB0022742D0 (en) | 2000-09-15 | 2000-11-01 | Smithkline Beecham Biolog | Vaccine |
CA2426738A1 (en) | 2000-10-26 | 2002-05-02 | David William Holden | Streptococcal genes |
EP2277894A1 (en) | 2000-10-27 | 2011-01-26 | Novartis Vaccines and Diagnostics S.r.l. | Nucleic acids and proteins from streptococcus groups A & B |
AT410798B (en) | 2001-01-26 | 2003-07-25 | Cistem Biotechnologies Gmbh | METHOD FOR IDENTIFYING, ISOLATING AND PRODUCING ANTIGENS AGAINST A SPECIFIC PATHOGEN |
GB0103171D0 (en) | 2001-02-08 | 2001-03-28 | Smithkline Beecham Biolog | Vaccine composition |
GB0103424D0 (en) | 2001-02-12 | 2001-03-28 | Chiron Spa | Gonococcus proteins |
AU2002306849A1 (en) | 2001-03-21 | 2002-10-08 | Elitra Pharmaceuticals, Inc. | Identification of essential genes in microorganisms |
GB0107661D0 (en) | 2001-03-27 | 2001-05-16 | Chiron Spa | Staphylococcus aureus |
GB0108079D0 (en) | 2001-03-30 | 2001-05-23 | Microbial Technics Ltd | Protein |
ATE557041T1 (en) | 2001-05-18 | 2012-05-15 | Us Gov Health & Human Serv | PEPTIDE VACCINES AGAINST GROUP A STREPTOCOCCE |
EP2320233A1 (en) | 2001-06-15 | 2011-05-11 | Inhibitex, Inc. | Cross-reactive monoclonal and polyclonal antibodies which recognize surface proteins from coagulase-negative staphylococci and staphylococcus aureus |
GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
US7410647B2 (en) | 2001-08-02 | 2008-08-12 | University Of Sheffield | Antigenic polypeptides |
JP4413617B2 (en) | 2001-12-12 | 2010-02-10 | カイロン ソチエタ ア レスポンサビリタ リミタータ | Immunization against CHLAMYDIATRACHOMATIS |
GB0203403D0 (en) | 2002-02-13 | 2002-04-03 | Chiron Spa | Chlamydia cytotoxic-T cell epitopes |
AU2003242955B2 (en) | 2002-04-02 | 2009-04-09 | Ben-Gurion University Of The Negev Research And Development Authority | Protein-based streptococcus pneumoniae vaccines |
GB0210128D0 (en) | 2002-05-02 | 2002-06-12 | Chiron Spa | Nucleic acids and proteins from streptococcus groups A & B |
RU2004135541A (en) | 2002-06-11 | 2005-10-10 | ГлаксоСмитКлайн Байолоджикалз с.а. (BE) | IMMUNOGENIC COMPOSITIONS |
GB0213622D0 (en) | 2002-06-13 | 2002-07-24 | Glaxosmithkline Biolog Sa | Vaccine Corporation |
US20060240045A1 (en) | 2002-08-02 | 2006-10-26 | Francois-Xavier Berthet | Neisserial vaccine compositions comprising a combination of antigens |
GB0220194D0 (en) | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
AU2003299535A1 (en) | 2002-09-13 | 2004-06-07 | Chiron Corporation | Group b streptococcus vaccine |
DK1549338T3 (en) | 2002-10-11 | 2011-03-28 | Novartis Vaccines & Diagnostic | Polypeptide vaccines for broad protection against hypervirulent meningococcal lineages |
GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
JP2006512338A (en) * | 2002-12-12 | 2006-04-13 | ファルマシア・コーポレーション | Use of aminocyanopyridines as mitogen-activated protein kinase-activated protein kinase-2 inhibitors |
ES2529736T3 (en) | 2003-04-10 | 2015-02-25 | Novartis Vaccines And Diagnostics, Inc. | Immunogenic composition comprising a SARS coronavirus spicular protein |
EP1615950A2 (en) | 2003-04-15 | 2006-01-18 | Intercell AG | S. pneumoniae antigens |
CA2526106A1 (en) | 2003-06-26 | 2005-01-13 | Chiron Corporation | Immunogenic compositions for chlamydia trachomatis |
GB0316560D0 (en) | 2003-07-15 | 2003-08-20 | Chiron Srl | Vesicle filtration |
WO2005032582A2 (en) | 2003-07-31 | 2005-04-14 | Chiron Corporation | Immunogenic compositions for streptococcus pyogenes |
JP2007528217A (en) | 2004-02-18 | 2007-10-11 | メルク エンド カムパニー インコーポレーテッド | Polypeptide for inducing a protective immune response against Staphylococcus aureus |
GB0419627D0 (en) | 2004-09-03 | 2004-10-06 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
EP2305295B1 (en) | 2004-09-22 | 2015-04-01 | GlaxoSmithKline Biologicals SA | Antibody composition for use in vaccination against staphylococcei |
PT2682126T (en) | 2005-01-27 | 2017-02-28 | Children`S Hospital & Res Center At Oakland | Gna1870-based vesicle vaccines for broad spectrum protection against diseases caused by neisseria meningitidis |
AU2006342053A1 (en) | 2005-12-27 | 2007-10-25 | Obetech, Llc | Adipogenic adenoviruses as a biomarker for disease |
WO2008019162A2 (en) | 2006-01-18 | 2008-02-14 | University Of Chicago | Compositions and methods related to staphylococcal bacterium proteins |
MX2008010604A (en) | 2006-02-17 | 2009-03-05 | Novartis Ag | Purification of bacterial antigens. |
AR060188A1 (en) | 2006-03-30 | 2008-05-28 | Glaxosmithkline Biolog Sa | CONJUGATION PROCEDURE |
NZ595178A (en) | 2006-03-30 | 2013-03-28 | Glaxosmithkline Biolog Sa | Vaccine comprising Type 5 and Type 8 capsular polysaccharides from Staphyloccocus aureus |
PL2268618T3 (en) | 2008-03-03 | 2015-11-30 | Novartis Ag | Compounds and compositions as tlr activity modulators |
CN101422437A (en) * | 2008-11-14 | 2009-05-06 | 李铁军 | Etoposide dry suspension and preparation method thereof |
WO2010144734A1 (en) * | 2009-06-10 | 2010-12-16 | Novartis Ag | Benzonaphthyridine-containing vaccines |
EP2470204B1 (en) | 2009-08-27 | 2015-12-16 | GlaxoSmithKline Biologicals SA | Hybrid polypeptides including meningococcal fhbp sequences |
TWI445708B (en) | 2009-09-02 | 2014-07-21 | Irm Llc | Compounds and compositions as tlr activity modulators |
-
2010
- 2010-12-15 CN CN2010800637486A patent/CN102762206A/en active Pending
- 2010-12-15 BR BR112012014624A patent/BR112012014624A8/en not_active Application Discontinuation
- 2010-12-15 MX MX2012006987A patent/MX339146B/en active IP Right Grant
- 2010-12-15 AU AU2010339921A patent/AU2010339921B2/en active Active
- 2010-12-15 WO PCT/US2010/060621 patent/WO2011084549A1/en active Application Filing
- 2010-12-15 EP EP10799189.5A patent/EP2512478B1/en active Active
- 2010-12-15 US US13/516,227 patent/US9408907B2/en active Active
- 2010-12-15 SG SG10201501980SA patent/SG10201501980SA/en unknown
- 2010-12-15 JP JP2012544804A patent/JP5814933B2/en active Active
- 2010-12-15 ES ES10799189.5T patent/ES2631977T3/en active Active
- 2010-12-15 CA CA2784580A patent/CA2784580A1/en not_active Abandoned
- 2010-12-15 SG SG2012044012A patent/SG181712A1/en unknown
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2015
- 2015-04-28 JP JP2015091257A patent/JP2015134828A/en not_active Withdrawn
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2016
- 2016-07-05 US US15/201,651 patent/US10046048B2/en active Active
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JP5814933B2 (en) | 2015-11-17 |
MX2012006987A (en) | 2012-07-17 |
BR112012014624A8 (en) | 2017-12-26 |
CA2784580A1 (en) | 2011-07-14 |
EP2512478A1 (en) | 2012-10-24 |
EP2512478B1 (en) | 2017-04-19 |
JP2015134828A (en) | 2015-07-27 |
JP2013514382A (en) | 2013-04-25 |
MX339146B (en) | 2016-05-13 |
US10046048B2 (en) | 2018-08-14 |
AU2010339921B2 (en) | 2016-08-11 |
US9408907B2 (en) | 2016-08-09 |
BR112012014624A2 (en) | 2016-03-01 |
AU2010339921A1 (en) | 2012-07-12 |
SG181712A1 (en) | 2012-07-30 |
CN102762206A (en) | 2012-10-31 |
WO2011084549A1 (en) | 2011-07-14 |
ES2631977T3 (en) | 2017-09-07 |
US20160375132A1 (en) | 2016-12-29 |
US20130101629A1 (en) | 2013-04-25 |
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