SE9803518D0 - Novel compounds - Google Patents
Novel compoundsInfo
- Publication number
- SE9803518D0 SE9803518D0 SE9803518A SE9803518A SE9803518D0 SE 9803518 D0 SE9803518 D0 SE 9803518D0 SE 9803518 A SE9803518 A SE 9803518A SE 9803518 A SE9803518 A SE 9803518A SE 9803518 D0 SE9803518 D0 SE 9803518D0
- Authority
- SE
- Sweden
- Prior art keywords
- novel compounds
- compounds
- tautomers
- prophylaxis
- enantiomers
- Prior art date
Links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
There are provided novel compounds of formula (I), wherein R<1>, R<2>, R<3>, R<4>, R<5>, A, Q, X, Y and Z are defined in the specification, and pharmaceutically acceptable salts thereof, and enantiomers and tautomers thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of the enzyme nitric oxide synthase and are thereby particularly useful in the treatment of prophylaxis of inflammatory disease and pain.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9803518A SE9803518D0 (en) | 1998-10-15 | 1998-10-15 | Novel compounds |
PCT/SE1999/001829 WO2000021934A1 (en) | 1998-10-15 | 1999-10-11 | Compounds |
AU14242/00A AU1424200A (en) | 1998-10-15 | 1999-10-11 | Compounds |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9803518A SE9803518D0 (en) | 1998-10-15 | 1998-10-15 | Novel compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
SE9803518D0 true SE9803518D0 (en) | 1998-10-15 |
Family
ID=20412958
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9803518A SE9803518D0 (en) | 1998-10-15 | 1998-10-15 | Novel compounds |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU1424200A (en) |
SE (1) | SE9803518D0 (en) |
WO (1) | WO2000021934A1 (en) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7199135B2 (en) | 2001-07-05 | 2007-04-03 | H. Lundbeck A/S | Substituted alkyl amido piperidines |
US7105544B2 (en) | 2001-07-05 | 2006-09-12 | Synaptic Pharmaceutical Corporation | Substituted alkyl amido piperidines |
EP1449841A1 (en) * | 2003-02-19 | 2004-08-25 | Bayer CropScience SA | New fungicidal compounds |
EP1771439A1 (en) * | 2004-07-23 | 2007-04-11 | Bayer CropScience S.A. | 4-pyridinylethylcarboxamide derivatives useful as fungicides |
EP1741709A1 (en) * | 2005-06-28 | 2007-01-10 | Sanofi-Aventis Deutschland GmbH | Heteroaryl-substituted amides comprising a saturated linker group, and their use as pharmaceuticals |
AR059898A1 (en) | 2006-03-15 | 2008-05-07 | Janssen Pharmaceutica Nv | DERIVATIVES OF 3-CIANO-PIRIDONA 1,4-DISUSTITUTED AND ITS USE AS ALLOSTERIC MODULATORS OF MGLUR2 RECEIVERS |
TW200845978A (en) | 2007-03-07 | 2008-12-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives |
TW200900065A (en) | 2007-03-07 | 2009-01-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives |
BRPI0816767B8 (en) | 2007-09-14 | 2021-05-25 | Addex Pharmaceuticals Sa | compound 4-phenyl-3,4,5,6-tetrahydro-2h,1'h-[1,4']bipyridinyl-2'-disubstituted 1',3'-ones, pharmaceutical composition and use of same |
ES2439291T3 (en) | 2008-09-02 | 2014-01-22 | Janssen Pharmaceuticals, Inc. | 3-Azabicyclo [3.1.0] hexyl derivatives as modulators of metabotropic glutamate receptors |
WO2010060589A1 (en) | 2008-11-28 | 2010-06-03 | Ortho-Mcneil-Janssen Pharmaceuticals, Inc. | Indole and benzoxazine derivatives as modulators of metabotropic glutamate receptors |
NZ596053A (en) | 2009-05-12 | 2013-05-31 | Janssen Pharmaceuticals Inc | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
CN102439008B (en) | 2009-05-12 | 2015-04-29 | 杨森制药有限公司 | 1,2,3-triazolo [4,3-a] pyridine derivatives and their use for the treatment or prevention of neurological and psychiatric disorders |
MY153913A (en) | 2009-05-12 | 2015-04-15 | Janssen Pharmaceuticals Inc | 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
US9271967B2 (en) | 2010-11-08 | 2016-03-01 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors |
ES2536433T3 (en) | 2010-11-08 | 2015-05-25 | Janssen Pharmaceuticals, Inc. | 1,2,4-Triazolo [4,3-a] pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors |
US8993591B2 (en) | 2010-11-08 | 2015-03-31 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a] pyridine derivatives and their use as positive allosteric modulators of MGLUR2 receptors |
JO3368B1 (en) | 2013-06-04 | 2019-03-13 | Janssen Pharmaceutica Nv | 6,7-DIHYDROPYRAZOLO[1,5-a]PYRAZIN-4(5H)-ONE COMPOUNDS AND THEIR USE AS NEGATIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS |
JO3367B1 (en) | 2013-09-06 | 2019-03-13 | Janssen Pharmaceutica Nv | 1,2,4-TRIAZOLO[4,3-a]PYRIDINE COMPOUNDS AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS |
DK3096790T3 (en) | 2014-01-21 | 2019-10-07 | Janssen Pharmaceutica Nv | COMBINATIONS INCLUDING POSITIVE ALLOSTERIC MODULATORS OR ORTHOSTERIC AGONISTS OF METABOTROP GLUTAMATERG SUBTYPE 2 RECEPTOR AND APPLICATION OF THESE |
DK3431106T3 (en) | 2014-01-21 | 2021-03-15 | Janssen Pharmaceutica Nv | COMBINATIONS INCLUDING POSITIVE ALLOSTERIC MODULATORS OR ORTHOSTERIC AGONISTS OF METABOTROP GLUTAMATERG SUBTYPE 2 RECEPTOR AND USE OF THESE |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997024122A1 (en) * | 1995-12-29 | 1997-07-10 | Smithkline Beecham Corporation | Vitronectin receptor antagonists |
JP2000502354A (en) * | 1995-12-29 | 2000-02-29 | スミスクライン・ビーチャム・コーポレイション | Vitronectin receptor antagonist |
EP1471055A1 (en) * | 1996-03-29 | 2004-10-27 | Pfizer Inc. | 6-phenylpyridyl-2-amine derivatives |
-
1998
- 1998-10-15 SE SE9803518A patent/SE9803518D0/en unknown
-
1999
- 1999-10-11 WO PCT/SE1999/001829 patent/WO2000021934A1/en active Application Filing
- 1999-10-11 AU AU14242/00A patent/AU1424200A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU1424200A (en) | 2000-05-01 |
WO2000021934A1 (en) | 2000-04-20 |
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