SE9801617D0 - New compound - Google Patents
New compoundInfo
- Publication number
- SE9801617D0 SE9801617D0 SE9801617A SE9801617A SE9801617D0 SE 9801617 D0 SE9801617 D0 SE 9801617D0 SE 9801617 A SE9801617 A SE 9801617A SE 9801617 A SE9801617 A SE 9801617A SE 9801617 D0 SE9801617 D0 SE 9801617D0
- Authority
- SE
- Sweden
- Prior art keywords
- protein
- testis
- nucleic acid
- acid sequence
- fetal
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/8139—Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
A gene encoding a novel cystatin-related protein has been isolated from fetal male mouse gonad and adult male human testis. The novel protein has a potential role in inducing testis formation in fetal gonads. It is also highly probable that the protein inhibits testis tumor growth because of structural and functional similarities with tumor inhibiting cystatins. The corresponding nucleic acid sequence, as well as vectors and host cells containing the nucleic acid sequence, and pharmaceutical compositions containing the protein are also claimed.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9801617A SE9801617D0 (en) | 1998-05-08 | 1998-05-08 | New compound |
PCT/SE1999/000764 WO1999058565A1 (en) | 1998-05-08 | 1999-05-06 | Cystatin-related protein |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9801617A SE9801617D0 (en) | 1998-05-08 | 1998-05-08 | New compound |
Publications (1)
Publication Number | Publication Date |
---|---|
SE9801617D0 true SE9801617D0 (en) | 1998-05-08 |
Family
ID=20411238
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9801617A SE9801617D0 (en) | 1998-05-08 | 1998-05-08 | New compound |
Country Status (2)
Country | Link |
---|---|
SE (1) | SE9801617D0 (en) |
WO (1) | WO1999058565A1 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7109292B2 (en) * | 1999-03-08 | 2006-09-19 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
AU2441601A (en) * | 1999-12-23 | 2001-07-03 | Zymogenetics Inc. | Zcys5: a member of the cystatin superfamily |
AU2001279182A1 (en) * | 2000-08-07 | 2002-02-18 | Zymogenetics Inc. | Zcys9: a member of the cystatin superfamily |
AU2001286871A1 (en) * | 2000-09-01 | 2002-03-22 | Zymogenetics Inc. | Mammalian cystatin-8 and its use to inhibit cancer procoagulant protein |
EP1343813A4 (en) * | 2000-12-19 | 2004-11-17 | Smithkline Beecham Corp | Novel compounds |
CN100368018C (en) * | 2005-05-26 | 2008-02-13 | 福建医科大学 | Fumor invasion and metastasis resisting function and use of venin cysteine proteinase inhibitor |
-
1998
- 1998-05-08 SE SE9801617A patent/SE9801617D0/en unknown
-
1999
- 1999-05-06 WO PCT/SE1999/000764 patent/WO1999058565A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO1999058565A8 (en) | 2000-01-06 |
WO1999058565A1 (en) | 1999-11-18 |
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