SE9201281D0 - NEW HUMAN MONOCLONAL ANTIBODIES, AND A METHOD FOR PREPARATION THEREOF - Google Patents
NEW HUMAN MONOCLONAL ANTIBODIES, AND A METHOD FOR PREPARATION THEREOFInfo
- Publication number
- SE9201281D0 SE9201281D0 SE9201281A SE9201281A SE9201281D0 SE 9201281 D0 SE9201281 D0 SE 9201281D0 SE 9201281 A SE9201281 A SE 9201281A SE 9201281 A SE9201281 A SE 9201281A SE 9201281 D0 SE9201281 D0 SE 9201281D0
- Authority
- SE
- Sweden
- Prior art keywords
- preparation
- human monoclonal
- monoclonal antibodies
- new human
- antibodies
- Prior art date
Links
- 241000701022 Cytomegalovirus Species 0.000 abstract 2
- 101001038300 Homo sapiens Protein ERGIC-53 Proteins 0.000 abstract 2
- 102100040252 Protein ERGIC-53 Human genes 0.000 abstract 2
- 101000933973 Salmonella phage Felix O1 (isolate Felix O1-VT1) Major capsid protein Proteins 0.000 abstract 2
- 210000005104 human peripheral blood lymphocyte Anatomy 0.000 abstract 1
- 230000003472 neutralizing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
- C07K16/085—Herpetoviridae, e.g. pseudorabies virus, Epstein-Barr virus
- C07K16/089—Cytomegalovirus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
- C12N2710/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Immunology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
New human monoclonal antibodies with neutralizing activity against the cytomegalovirus (CMV). A method for preparation of such antibodies is also described, whereby the antibodies are produced from human peripheral blood lymphocytes. The antibodies are specific for epitopes between aa 552-635 of gp58 or aa 67-86 of gp116 and recognize native gp58/gp116 as well.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9201281A SE9201281L (en) | 1992-04-23 | 1992-04-23 | Novel human monoclonal antibodies and process for their preparation |
PCT/SE1993/000343 WO1993021952A1 (en) | 1992-04-23 | 1993-04-21 | Human monoclonal antibodies against cytomegalovirus and method for preparation thereof |
AU42742/93A AU4274293A (en) | 1992-04-23 | 1993-04-21 | Human monoclonal antibodies against cytomegalovirus and method for preparation thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9201281A SE9201281L (en) | 1992-04-23 | 1992-04-23 | Novel human monoclonal antibodies and process for their preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
SE9201281D0 true SE9201281D0 (en) | 1992-04-23 |
SE9201281L SE9201281L (en) | 1993-10-24 |
Family
ID=20386038
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9201281A SE9201281L (en) | 1992-04-23 | 1992-04-23 | Novel human monoclonal antibodies and process for their preparation |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU4274293A (en) |
SE (1) | SE9201281L (en) |
WO (1) | WO1993021952A1 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19756214C1 (en) * | 1997-12-17 | 1999-02-25 | Biotest Ag | New chimeric human cytomegalovirus (HCMV) polypeptides |
DE60329526D1 (en) | 2002-11-15 | 2009-11-12 | Morphotek Inc | METHOD OF GENERATING HIGH ANTIBODY PRODUCTION OF HYBRIDOMAS RESULTING FROM IN VITRO IMMUNIZATION |
US7947274B2 (en) | 2007-01-04 | 2011-05-24 | Humabs, LLC. | Human cytomegalovirus neutralising antibodies and use thereof |
GB0700133D0 (en) | 2007-01-04 | 2007-02-14 | Humabs Llc | Human cytomegalovirus neutralising antibodies and use thereof |
WO2009024445A1 (en) * | 2007-08-22 | 2009-02-26 | Ribovax Biotechnologies Sa | Antibodies against human cytomegalovirus (hcmv) |
JP5544309B2 (en) | 2008-03-10 | 2014-07-09 | セラクローン サイエンシーズ, インコーポレイテッド | Compositions and methods for treatment and diagnosis of cytomegalovirus infection |
EP3178845A1 (en) | 2008-07-16 | 2017-06-14 | Institute for Research in Biomedicine | Human cytomegalovirus neutralizing antibodies and use thereof |
EP2420572B1 (en) | 2009-04-01 | 2015-03-25 | Evec Incorporated | Monoclonal antibody capable of binding to specific discontinuous epitope occurring in ad1 region of human cytomegalovirus gb glycoprotein, and antigen-binding fragment thereof |
SG181901A1 (en) | 2009-12-23 | 2012-08-30 | 4Antibody Ag | Binding members for human cytomegalovirus |
US20150152166A1 (en) * | 2013-04-19 | 2015-06-04 | Theraclone Sciences, Inc. | Compositions and methods for the therapy and diagnosis of cytomegalovirus |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR910000736B1 (en) * | 1985-12-06 | 1991-02-06 | 데이진 가부시키가이샤 | Anticytomegalo virus human monoclonal antibody and process for its preparation |
-
1992
- 1992-04-23 SE SE9201281A patent/SE9201281L/en not_active Application Discontinuation
-
1993
- 1993-04-21 AU AU42742/93A patent/AU4274293A/en not_active Abandoned
- 1993-04-21 WO PCT/SE1993/000343 patent/WO1993021952A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO1993021952A1 (en) | 1993-11-11 |
SE9201281L (en) | 1993-10-24 |
AU4274293A (en) | 1993-11-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU648506B2 (en) | Erythropoietin (EPO) peptides and antibodies directed against these | |
ATE512224T1 (en) | RECONSTITUTED HUMAN ANTI-HM.1 ANTIBODIES | |
NO970221D0 (en) | Human neutralizing monoclonal antibodies against human immunodeficiency virus | |
AU2349697A (en) | Monoclonal antibodies against the interferon receptor with neutralizing activity against type I interferon | |
PT941121E (en) | LIPOPILIZED PHARMACEUTICAL PREPARATIONS, STABLE, OF MONOCLONAL OR POLYCLONAL ANTIBODIES | |
ATE233814T1 (en) | HUMAN NEUTRALIZING MONOCLONAL ANTIBODY AGAINST THE VIRUS THAT CAUSES HUMAN IMMUNE DEFICIENCY | |
GR3029774T3 (en) | Method of preparing a radioactive rhenium complex solution. | |
EP0314402A3 (en) | Monoclonal antibodies against human interleukin-4 and hybridomas producing the same | |
ES2133139T3 (en) | BISPECIFIC ANTIBODIES HETERO WITH DOUBLE EFFECTIVE FUNCTIONS. | |
KR890002547A (en) | Monoclonal antibodies and peptides for the treatment and diagnosis of HIV infection | |
NO910209L (en) | PROCEDURE FOR THE PREPARATION OF RECOMBINANT HUMAN ANTI-CD18 ANTIBODIES. | |
NO870476D0 (en) | PROCEDURE FOR THE PREPARATION OF CROSS PROTECTIVE HUMAN MONOCLONAL ANTIBODY PREPARATIONS. | |
SE9201281D0 (en) | NEW HUMAN MONOCLONAL ANTIBODIES, AND A METHOD FOR PREPARATION THEREOF | |
CA2008817A1 (en) | M-csf monoclonal antibodies that recognize a neutralizing conformational epitope | |
CA2185112A1 (en) | Humanized monoclonal antibodies against human interleukin-4 | |
AU7203194A (en) | Bispecific human monoclonal antibodies specific for human immunodeficiency virus | |
MX9301858A (en) | RECOMBINANT HIV-HUMAN NEUTRALIZING MONOCLONAL ANTIBODIES FOR THE PREVENTION AND TREATMENT OF HIV INFECTION. | |
AU2133292A (en) | Hcmv-specific peptides, agents therefor and the use thereof | |
KR890700683A (en) | Methods for searching for antibodies against human immunodeficiency virus | |
DK69690A (en) | HUMAN ANTI-RH (D) MONOCLONAL ANTIBODIES | |
NO883603L (en) | HUMAN MONOCLONAL ANTIBODIES AND PROPHYLACTIC AND THERAPEUTIC AGENTS FOR INFECTIOUS DISEASES INCLUDING THESE EFFECTIVE COMPONENT. | |
NO874107L (en) | NEW MONOCLONAL ANTIBODIES AGAINST IFN-WAA, PROCEDURE FOR PRODUCING THEREOF AND APPLICATION FOR PURIFICATION AND DETECTION OF IFN-OMEGA. | |
DE376770T1 (en) | USE OF HUMAN IMMUNOGLOBULIN G OR FC FRAGMENTS, LIKE PREPARATORY MEDICINES FOR THE ADMINISTRATION OF MONOCLONAL ANTIBODIES TO HUMANS. | |
AU582129B2 (en) | Circulating antigens of dirofilaria immitis,monoclonal antibodies specific therefor and methods of preparing such antibodies and detecting such antigens | |
EP0334076A3 (en) | Monoclonal antibody capable of recognizing an antigen associated with human arteriosclerosis, and process for preparing the same |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
NAV | Patent application has lapsed |
Ref document number: 9201281-4 |