RU2238076C1 - Method for treating and preventing diseases due to affecting biologically active points and areas - Google Patents

Abstract

FIELD: medicine, reflexotherapy.

SUBSTANCE: one should affect biologically active points and biologically active areas with injection of medicinal substances, for example, "Alloplant" biomaterial. The latter is diluted in physiological solution at the ratio of 10:100 mg biomaterial per 5-15 ml physiological solution. The quantity of seances corresponds to 1-10 at periodicity being 2-7 d.

EFFECT: more prolonged action.

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Description

The invention relates to medicine, namely to reflexology, and can be used to treat patients with various diseases, as well as for the prevention of diseases.

Reflexotherapy is known to be the oldest method. Oriental medicine has gained vast experience in the treatment of many diseases by the method of therapeutic effect on biologically active points (BAP) and biologically active zones (BAS). The desire to increase the effectiveness of traditional reflexology (acupuncture) encourages the development of new ways to influence BAP. Many methods have been developed to influence these points and zones; acupuncture, moxibustion, their combination, acupressure, the use of needle rollers and hammers, aeroion massage, exposure to electric, magnetic field, laser beam, the introduction of various substances at points. The main disadvantages of these methods are the short duration of the exposure and the instability of the results, which makes it necessary to use a large number of sessions per course and often repeat reflexology courses.

In addition, the frequent use of acupuncture and cauterization at a certain point often causes its depletion and even scarring, which reduces the therapeutic effect.

Acupressure (acupressure), as well as the use of needle hammers and rollers provide a weak surface effect and also require a lot of time. Fixation to the point of various objects (tsubo) provides, albeit a long, but slightly pronounced effect. Hardware methods (aeroion-, electro-, magneto, laser stimulation of points), in addition to the availability of special equipment, also require a lot of time to treat one patient.

A known method of influencing trigger and acupuncture points by piercing them with an injection needle with a perforated side surface (RF patent No. 2138242, IPC A 61 H 39/08, publ. 09/27/1999). The time spent by the needle at the point is at least 5-10 minutes, the number of sessions is 3-5. This method is aimed at achieving predominantly inhibitory reflexotherapy effects. It does not allow the stimulation of points, does not provide a prolonged therapeutic effect. In addition, the use of this needle leads to trauma to tissue structures with subsequent depletion and scarring of the point.

Longer stimulation of BAT and BAS allows you to achieve the method of flashing subcutaneous tissue with biomaterial - catgut thread in the projection of BAT and BAZ (Sobetsky V.V., Reflexotherapy in clinical practice. Kiev, Zdorovya, 1993, p. 82-89). Long-term resorption of catgut provides long-term stimulation of the points. But the catgut flashing procedure is rather traumatic, requires special conditions for its implementation (operating room). In addition, catgut can cause severe tissue reactions up to rejection, allergic reactions.

Closest to the proposed method is the injection of drugs into the BAT (pharmacopuncture) (Acupuncture / under the general editorship of HOANG BAO TYAU. M: Medicine, 1988, p. 544-462). The method allows you to combine the general effect of the drug (describe the use of ATP, vitamins, proserin) with local irritation points. But these drugs, rapidly eliminating from the point, can not have a long stimulating effect on it. In addition, the possibility of side effects of drugs (idiosyncrasies, allergic reactions, toxic complications, etc.) cannot be ruled out, which significantly limits the indications for using this method.

The proposed invention is aimed at increasing the effectiveness of treatment due to immunostimulation and immunocorrection, enhancing the regenerative abilities of cells, activation of biochemical processes. In addition, the invention allows to reduce the morbidity and reduce the duration of treatment,

The problem is achieved by the method of influencing biologically active points and biologically active zones by injection of medicinal substances into them, in which, unlike the prototype, “Alloplant” biomaterial diluted in physiological saline in a ratio of 10-100 mg of biomaterial is used as medicinal substances “Alloplant” for 5-15 ml of physiological saline, and injections are carried out with sessions in an amount of 1-10 with a frequency of 2-7 days.

The Alloplant biomaterial, developed at the All-Russian Center for Ophthalmic and Plastic Surgery and approved for wide clinical use (TU No. 42-2-537-93 of the Ministry of Health of Russia), has the following advantages compared to other drugs used for injection:

- convenience, safety and painlessness of administration - not requiring special operating room conditions;

- long-term stimulation of the point, providing a prolonged effect;

- low antigenic properties;

- prevention of scarring and stimulation of full regeneration;

- improvement of local immunity for the prevention of infectious complications.

The unique properties of the Alloplant biomaterial obtained from donor cadaveric material in accordance with the Law of the Russian Federation "On Organ and Tissue Transplantation" No. 4181-1 of November 22, 1992, specially processed (more than 80 types of Alloplant biomaterial have been developed) allow widely use it in such fields of medicine as ophthalmology, dentistry, neurosurgery, gynecology, breast surgery, etc.

The developed special biomaterial for reflexology (for acupuncture administration) meets all the requirements of the task: releasing it in powder or liquid form, sealed in sterile bottles, makes it convenient to use, while preserving all the requirements for asepsis and antiseptics in a treatment room. Available forms of "alloplant" make it possible to introduce it through an insulin needle. According to morphological studies, particles of this allograft are resorbed in tissues by tissue macrophages for 3-4 weeks, which provides a prolonged effect of stimulation of BAP and BAS. Its ability to attract immune cells, mainly macrophages, significantly reduces the likelihood of infectious complications

Low antigenic properties exclude its rejection and patient allergization, which is confirmed by almost 30 years of experience with the use of Alloplant biomaterials. The ability to stimulate full regeneration prevents scarring of BAP with frequent exposure to it, and its ability to absorb scar tissue allows it to be used to activate BAT, which for some reason underwent scarring (post-burn, postoperative scars, scars after chi-cauterization, multiple acupuncture )

Using the injection method of influencing points allows reducing the time of work with the patient depending on the number of injections instead of 2-3 hours to 15-20 minutes. The indicated forms of Alloplant biomaterial do not irritate the tissues at the injection site, which makes the procedure painless in contrast to the use of other drugs (for example, such as aloe, vitamins, etc.). The release form (in a sterile bottle) allows you to achieve a long shelf life (5 years) without losing its properties.

Known chipping of scar tissue, postoperative wounds, ulcers with dispersed Alloplant biomaterial with a positive result due to its special regenerative and stimulating properties. However, this is a local effect aimed at restoring and healing tissues in a specific area.

The proposed method allows you to provide a general long-term (3-4 weeks) effect on the human body through the BAP and BAS systems, aimed at stable restoration of the underlying mechanisms of nervous regulation, metabolic processes, increase immunity of both humoral and cellular, thereby ensuring restoration and duration of conservation normal homeostasis. This new effect from the treatment and prevention of diseases is achieved thanks to the proposed combination of essential features, ensuring that the invention meets the criterion of “inventive step”.

The method is as follows. The patient has clinically relevant BAT and BAS, located along the course of the interested myoviscerofascial connections, tendon-muscle meridians and pathologically stabilized motor synergies. The recipe (set) of points is determined in accordance with the methods of traditional reflexology, pulse diagnostics, according to the method of Voll, Nakatani, etc. At the selected points, injections with an insulin needle diluted in saline Alloplant biomaterial in the ratio: 10-100 mg of Alloplant biomaterial per 5-15 ml of physiological saline are made.

The skin surface in the area of BAP and BAS is treated with 70% medical alcohol. Injections are usually given subcutaneously, although the intradermal, intramuscular, and even subperiosteal route of administration is not excluded. After the injection, it is advisable to massage the injection site slightly with a pressed alcohol cotton ball to reduce pain and "block energy". The number of BAT and BAZ used in the prescription is from 3-5 to 10-30, which depends on the patient's condition and his disease. The volume of injected Alloplant liquid form is from 0.25 to 1.5 ml, which depends on the location of the point, the development of subcutaneous fat, weight and age of the patient ..

Treatment is carried out with sessions in an amount of 1-10 with a frequency of 2-7 days, which depends on the disease, the condition of the patient and the objectives of the treatment or preventive direction.

Example 1. Patient S. 12 years. Ds: OP (both eyes) moderate progressive myopia, retinal dystrophy. Electrophysiological study (EFI) by Kompaneitsa revealed a deterioration in email. sensitivity OD (right eye - up to 130 μA, OS (left eye) - up to 160 μA, total fields of view according to Goldman OD ∑ 210 °, OS ∑ 290 °. According to the electropuncture diagnostics according to R. Voll and traditional muscle-tendon diagnostics detected insufficiency and imbalance along the meridians F, VB, R, VE

The patient underwent 3 sessions of acupuncture administration of Alloplant biomaterial: the 1st session, a dosage of 30 mg per 8 ml of saline, the 2nd session, after 4 days, the dosage of 40 mg per 10 ml of saline, the 3rd session after 3 days - 50 mg, dosage of 50 mg per 10 ml of saline. The following points were used in the formulation: distal - VB 39, TR8, F3, E36; corporal - VB24, VI 8, V19, U23, BA-LNAO, T14; cranial and paraorbital - T20, TR20 VI VB1 El TR 23. The volume of injected suspension Alloplant ranged from 0.5 ml for cranial and paraorbital points to 0.8-1.0 ml for corporal and distal points.

After the course, the patient subjectively has an improvement in overall well-being, an increase in brightness in the eyes, objectively: EFI OD - electrical sensitivity improved to 80 μA (normal), OS - to 100 μA, the field of view OD ∑ 335 °, OS ∑ 410 °, indicators of biologically active points according to R. Voll were normalized and stabilized. The patient was observed for 1 year. Visual functions are stable, the progression of myopia was not observed.

Example 2. Patient W. 19 years. Ds: peptic ulcer of the duodenum, sick 4 years. With a growth of 180 cm, it has a weight of 62 kg. Medication is ineffective. He complained of constant aching pain in the epigastric region, worse at night, heartburn, a feeling of bitterness in the mouth, general weakness and fatigue. According to the FGS: on the front and back walls of the duodenum, chronic collic ulcers are ×5 × 8 mm and 12 × 10 mm. According to Voll electropuncture diagnostics, an excess in the E and J _g meridians, insufficiency in the C and RP meridians, the phenomenon of "falling arrows" in most meridians are revealed.

4 sessions of acupuncture administration of Alloplant biomaterials were performed: the 1st session - 30 mg, the 2nd - 40 mg, 3 and 4 - 50 mg, diluted in 10.0 ml of saline. Sessions were held with a frequency of 4 days. According to Voll electropuncture diagnostics, which was carried out before each session, the points were used: RPU, MC6, TR8, Gi4, VB 39, E36, E25, V21-27, VB 24, T24, SZ, scalp zones - hepatobiliary and gastroduodenal. Depending on the location of the point, 0.3 to 1.5 ml of Alloplant biomaterial was introduced. The recipe included 8-16 points per session.

After the course of therapy, pain in the epigastric region and heartburn completely disappeared, appetite appeared, the “fall of the arrow” according to Voll disappeared, ulcer epithelization was noted on the FGS. The patient was observed for 6 months. She feels well. He added 16 kg in weight - the growth-weight coefficient returned to normal. Started playing sports.

Example 3. Patient C. 29 years. Ds: chronic viral hepatitis C. Complaints of fatigue, headaches, a feeling of heaviness in the right hypochondrium, bitterness in labor, nausea. An objective examination determines a slight increase in the liver and soreness of its lower edge. Blood biochemistry: bilirubin 32.4 μmol / L, ALT 66.8 ME, ACT 26 ME, immunological analysis: JgG - 6, Jg M - 1.8, Jg A - 1.9, proliferative activity of lymphocytes - 0.02 , phagocytic index 23, phagocytic number 3.6. A course of acupuncture introduction of Alloplant biomaterial consisting of 3 sessions was carried out. 30, 50, and 50 mg of Alloplant biomaterial, diluted in 10.0 ml of physiological saline, were respectively administered. Before each session, BAT indicators were measured according to the R. Voll method to identify meridians that are in a state of insufficiency or instability ("arrow drop"). General blood and urine tests and selecting the appropriate points in the prescription. Points used: RP6, MC6, TR8, VB39, V18-19, Vb24-F13, VC1, VBM-20, scalp "gastroduodenal zone". Microinjections (up to 0.1 ml) to the point AP 97 (liver) and the “zero” point were also used.

After the course, there was a significant improvement in well-being - increased efficiency, ceased headaches, decreased dyspeptic symptoms. Blood biochemistry: bilirubin 22 g / l, ALT 51, ACT-21, immunology: JgG-13.3, JgM-1.1, LgA-1.6 proliferative activity of lymphocytes 0.15, phagocytic index 37, phagocytic number 7, 1.

Example 4. Patient S., born in 1943, the diagnosis of vegetative-vascular dystonia hypertonic type, widespread osteochondrosis. Complaints about: fatigue, periodic (despite the regular use of antihypertensive drugs) rises in blood pressure, constant pain in the occipital, cervical and lumbosacral region.

40 control points of measurement (CTI) were examined according to the R. Voll method: at 11 points “drop of the arrow” is determined, insufficiency in the meridians VB.GI (tendency to constipation), V (xp.cystitis).

Within 2 weeks, 4 sessions of subcutaneous administration of Alloplant biomaterial were performed:

1) to acupuncture points: Gi11, Gi4, E36, Vb39, VG24, lo-points of interested meridians;

2) in biologically active zones: Balao, trigger (trigger) zones along the paravertebral lines and in the cervical-collar region, scalp-vasomotor and hepatobiliary zones, as well as in areas of reflected pain (Zakharyin-Geda) with this pathology.

At the end of treatment, the patient notes a surge of strength, increased efficiency, pain almost stopped, blood pressure stabilized at 130 / 80-130 / 90 mm Hg. Control examination according to R. Voll - all indicators of CTI are stable. At re-examination after 7 months: the condition is satisfactory, there are no complaints, the back pain is not disturbing, the blood pressure is stable, the CTI according to R. Voll is stable. Conducted 1 session in BAT and BAZ according to the proven methodology with a preventive purpose.

Example 5. A group of employees of a bank in the city of Tolyatti - 21 people of various ages who work directly with clients, who often have ARVI and ARI in the cold season (autumn, winter, spring). 2 sessions of acupuncture administration of Alloplant biomaterial were carried out in order to prevent these diseases. Used BAT: Yang and Yin lo-points, VC17, 12, 7, Zakharyin-Geda zone (lungs) - cervical-collar region, scalp zone of the chest cavity. As a result, during the cold season, there were no cases of SARS, ARI in 19 people, 2 cases of mild ARVI, ARI were noted. Each of the group noted that during this period he repeatedly had contacts with patients with acute respiratory viral infections and acute respiratory infections. Along with an improvement in general condition, an improvement in working capacity was noted, as well as positive dynamics in the course of chronic diseases identified in this group of bank employees. The bank management notes the beneficial effect of the preventive effect and is set to continue cooperation.

Example 6. Patient M., 53 g. Ds: gastric cancer, highly differentiated adenocarcinoma. Two weeks before the operation, examinations were performed:

general blood test: Eg 4.5 · 10 ¹² ; Tsv.p 0.8; HB 110 g / l; T, 200; L 60 · 10 ⁹ ; E 5%; Np 10%; ns 70%; Li 15%; M 1%; ESR 35 mm / h, general urine analysis: slightly acidic, transparent, yellow, specific weight 1010; L 5 · 10 p.s.; protein neg.

By agreement with the patient and the attending physician, 3 sessions of acupuncture administration of Alloplant biomaterial were carried out:

1 session - 30 mg: 8 ml phys. solution;

2 session - 5 mg: 10 ml nat. solution;

3 session - 50 mg: 10 ml phys. solution;

BAT used: Yang and Yin lo points :, VC 1, 17, 12, 7; RP 6, MC 3, VB39, V 18, 19, 20, E 36:

BASIS: 1) scalp-gastroduodenal zone, hapatobiliary zone;

2) the Zacharyiva Geda zone is the liver.

Before the operation, a general blood test: Eg 4.8 · 10; Tsv.p 1,0, Nv 130 g / l; T _r 350; L 5.5 · 10 ⁹ ; E 1%; Np 7%; not 60%; Li 25%; M 1%; ESR 10 mm / h, general urine analysis: acidic, transparent light yellow, specific weight 1010; L: 5 · 10 p / sp; Eg neg., Protein neg.

Operation: performed a resection of the stomach according to Billroth 2, metastases were not detected. The postoperative period was uneventful, the patient spent 3 days in the intensive care unit (instead of the expected 5-7 days). The volume of circulating blood is normal. The wound healed by primary intention 10 days after surgery. General blood and urine tests are normal. General blood immunology is normal. The attending physician notes the rapid restoration of the patient's body functions after a complex operation. The patient is discharged on day 12.

The patient was observed for 3 years. General condition is satisfactory. General blood and urine tests are normal. FGS and an X-ray of the stomach relapse not noted. Every year, for the purpose of prevention, 1 session of acupuncture introduction of Alloplant biomaterial into the above BAT and BAS was conducted in a dosage of 50 mg: 10 ml.

Thus, the proposed invention allows to increase the effectiveness of the therapeutic and prophylactic effects on biologically active points and zones while reducing the morbidity and duration of treatment.

Claims (1)

A method for the treatment and prevention of diseases by affecting biologically active points and biologically active zones by injecting drug substances into them, characterized in that alloplant biomaterial diluted in physiological saline in a ratio of 10-100 mg of Alloplant biomaterial is used as pharmaceutical substances ”For 5-15 ml of physiological saline, and the injections are carried out with sessions in an amount of 1-10 with a frequency of 2-7 days.