PT3459953T - Novo derivado de 5h-pirrolo[2,3-d]pirimidin-6(7h)-ona - Google Patents
Novo derivado de 5h-pirrolo[2,3-d]pirimidin-6(7h)-onaInfo
- Publication number
- PT3459953T PT3459953T PT177995115T PT17799511T PT3459953T PT 3459953 T PT3459953 T PT 3459953T PT 177995115 T PT177995115 T PT 177995115T PT 17799511 T PT17799511 T PT 17799511T PT 3459953 T PT3459953 T PT 3459953T
- Authority
- PT
- Portugal
- Prior art keywords
- pyrrolo
- pyrimidin
- derivative
- novel
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2016101599 | 2016-05-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3459953T true PT3459953T (pt) | 2021-07-29 |
Family
ID=60325930
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT177995115T PT3459953T (pt) | 2016-05-20 | 2017-05-19 | Novo derivado de 5h-pirrolo[2,3-d]pirimidin-6(7h)-ona |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US10538528B2 (pt) |
| EP (1) | EP3459953B1 (pt) |
| JP (1) | JP6576553B2 (pt) |
| KR (1) | KR102149734B1 (pt) |
| CN (1) | CN109153681B (pt) |
| AU (1) | AU2017265769B9 (pt) |
| BR (1) | BR112018073721B1 (pt) |
| CA (1) | CA3024831C (pt) |
| DK (1) | DK3459953T3 (pt) |
| ES (1) | ES2882018T3 (pt) |
| HK (1) | HK1259613A1 (pt) |
| HU (1) | HUE055846T2 (pt) |
| MA (1) | MA45048A (pt) |
| MX (1) | MX2018014022A (pt) |
| MY (1) | MY185962A (pt) |
| PH (1) | PH12018502411A1 (pt) |
| PL (1) | PL3459953T3 (pt) |
| PT (1) | PT3459953T (pt) |
| RU (1) | RU2713181C1 (pt) |
| SG (1) | SG11201810360YA (pt) |
| TW (2) | TWI679202B (pt) |
| WO (1) | WO2017200087A1 (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023063432A1 (en) * | 2021-10-13 | 2023-04-20 | Taiho Pharmaceutical Co., Ltd. | Treatment methods for subjects having cancer with a dysregulated mapk and/or pi3k pathway |
| WO2023143424A1 (zh) * | 2022-01-27 | 2023-08-03 | 四川海思科制药有限公司 | 一种氮杂并环衍生物及其在医药上的应用 |
| WO2024009977A1 (ja) * | 2022-07-05 | 2024-01-11 | 大鵬薬品工業株式会社 | ５Ｈ－ピロロ［２，３－ｄ］ピリミジン－６（７Ｈ）－オン及びその塩体の結晶 |
| CN115850244B (zh) * | 2023-02-24 | 2023-05-16 | 成都大学 | 一种托吡司他的制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8076338B2 (en) * | 2004-04-23 | 2011-12-13 | Exelixis, Inc. | Kinase modulators and methods of use |
| GB0608184D0 (en) * | 2006-04-25 | 2006-06-07 | Astex Therapeutics Ltd | Pharmaceutical compounds |
| AR064416A1 (es) * | 2006-12-21 | 2009-04-01 | Cancer Rec Tech Ltd | Derivados de purina, piridina y pirimidina condensadas con heterociclos, moduladores de pka y/o pkb, composiciones farmaceuticas que los contienen, y usos para el tratamiento de enfermedades hiperproliferativas. |
| RU2517804C2 (ru) * | 2008-08-08 | 2014-05-27 | Нестек С.А. | Машина для приготовления напитков с ручкой для переноски, имеющая адаптируемый внешний вид и содержащая сменные боковые панели |
| AR074072A1 (es) * | 2008-11-11 | 2010-12-22 | Lilly Co Eli | Compuesto de imidazol -piperidin -pirrol-pirimidin-6-ona, composicion farmaceutica que lo comprende y su uso para preparar un medicamento util para tratar el glioblastoma multiforme |
| BR112012011328A2 (pt) * | 2009-10-23 | 2016-11-22 | Lilly Co Eli | inibidores de akt |
| WO2014143612A1 (en) * | 2013-03-11 | 2014-09-18 | Merck Patent Gmbh | 6-[4-(1 h-imidazol-2-yl)piperidin-1 -yl]pyrimidin-4-amine derivatives as modulators of kinase activity |
| JP6398659B2 (ja) | 2014-11-28 | 2018-10-03 | アイシン・エィ・ダブリュ株式会社 | 歯形部品の製造方法および歯形部品製造装置 |
-
2017
- 2017-05-19 JP JP2018518384A patent/JP6576553B2/ja active Active
- 2017-05-19 BR BR112018073721-6A patent/BR112018073721B1/pt active IP Right Grant
- 2017-05-19 WO PCT/JP2017/018825 patent/WO2017200087A1/ja active Application Filing
- 2017-05-19 MY MYPI2018704229A patent/MY185962A/en unknown
- 2017-05-19 EP EP17799511.5A patent/EP3459953B1/en active Active
- 2017-05-19 US US16/302,829 patent/US10538528B2/en active Active
- 2017-05-19 PL PL17799511T patent/PL3459953T3/pl unknown
- 2017-05-19 MX MX2018014022A patent/MX2018014022A/es active IP Right Grant
- 2017-05-19 PT PT177995115T patent/PT3459953T/pt unknown
- 2017-05-19 RU RU2018144542A patent/RU2713181C1/ru active
- 2017-05-19 TW TW106116606A patent/TWI679202B/zh active
- 2017-05-19 AU AU2017265769A patent/AU2017265769B9/en active Active
- 2017-05-19 CA CA3024831A patent/CA3024831C/en active Active
- 2017-05-19 MA MA045048A patent/MA45048A/fr unknown
- 2017-05-19 KR KR1020187030344A patent/KR102149734B1/ko active IP Right Grant
- 2017-05-19 DK DK17799511.5T patent/DK3459953T3/da active
- 2017-05-19 CN CN201780030144.3A patent/CN109153681B/zh active Active
- 2017-05-19 TW TW108107835A patent/TWI732187B/zh active
- 2017-05-19 HU HUE17799511A patent/HUE055846T2/hu unknown
- 2017-05-19 SG SG11201810360YA patent/SG11201810360YA/en unknown
- 2017-05-19 ES ES17799511T patent/ES2882018T3/es active Active
-
2018
- 2018-11-15 PH PH12018502411A patent/PH12018502411A1/en unknown
-
2019
- 2019-01-31 HK HK19101800.7A patent/HK1259613A1/zh unknown
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