PL382055A1 - Sposób wytwarzania formy krystalicznej 1 wodorosiarczanu klopidogrelu - Google Patents
Sposób wytwarzania formy krystalicznej 1 wodorosiarczanu klopidogreluInfo
- Publication number
- PL382055A1 PL382055A1 PL382055A PL38205507A PL382055A1 PL 382055 A1 PL382055 A1 PL 382055A1 PL 382055 A PL382055 A PL 382055A PL 38205507 A PL38205507 A PL 38205507A PL 382055 A1 PL382055 A1 PL 382055A1
- Authority
- PL
- Poland
- Prior art keywords
- clopidogrel
- production method
- crystalline form
- hydrogen sulphate
- sulphate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL382055A PL382055A1 (pl) | 2007-03-23 | 2007-03-23 | Sposób wytwarzania formy krystalicznej 1 wodorosiarczanu klopidogrelu |
EP08741764A EP2139902A1 (en) | 2007-03-23 | 2008-03-19 | Process for preparation of pure polymorphic form 1 of clopidogrel hydrogensulfate |
US12/531,888 US20100216999A1 (en) | 2007-03-23 | 2008-03-19 | Process for preparation of pure polymorphic form 1 of clopidogrel hydrogensulfate |
PCT/PL2008/000023 WO2008118030A1 (en) | 2007-03-23 | 2008-03-19 | Process for preparation of pure polymorphic form 1 of clopidogrel hydrogensulfate |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL382055A PL382055A1 (pl) | 2007-03-23 | 2007-03-23 | Sposób wytwarzania formy krystalicznej 1 wodorosiarczanu klopidogrelu |
Publications (1)
Publication Number | Publication Date |
---|---|
PL382055A1 true PL382055A1 (pl) | 2008-09-29 |
Family
ID=39628754
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL382055A PL382055A1 (pl) | 2007-03-23 | 2007-03-23 | Sposób wytwarzania formy krystalicznej 1 wodorosiarczanu klopidogrelu |
Country Status (4)
Country | Link |
---|---|
US (1) | US20100216999A1 (pl) |
EP (1) | EP2139902A1 (pl) |
PL (1) | PL382055A1 (pl) |
WO (1) | WO2008118030A1 (pl) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20110263858A1 (en) * | 2008-10-20 | 2011-10-27 | Satish Kumar Aryan | Process for the preparation of clopidogrel hydrogen sulphate form i |
WO2011042804A2 (en) * | 2009-10-08 | 2011-04-14 | Jubliant Life Sciences Limited | An improved process for the preparation of clopidogrel hydrogen sulfate form i |
WO2011051976A2 (en) * | 2009-10-30 | 2011-05-05 | Matrix Laboratories Ltd | An improved process for the preparation of clopidogrel bisulfate form i |
US20120232274A1 (en) * | 2009-11-09 | 2012-09-13 | Pharmazell Gmbh | Process for preparation of clopiodogrel bisulfate form-1 |
WO2011125069A1 (en) * | 2010-03-22 | 2011-10-13 | Rpg Life Sciences Limited | A process for preparation of crystalline form i of clopidogrel bisulfate |
CN102558194A (zh) * | 2010-12-11 | 2012-07-11 | 山东方明药业股份有限公司 | 一种硫酸氢氯吡格雷i型的制备方法 |
WO2020013305A1 (ja) * | 2018-07-12 | 2020-01-16 | 有機合成薬品工業株式会社 | クロピドグレル硫酸塩のi型結晶の製造方法 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2623810B2 (fr) * | 1987-02-17 | 1992-01-24 | Sanofi Sa | Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant |
HU225503B1 (en) * | 1997-05-13 | 2007-01-29 | Sanofi Aventis | Novel 2-(2-halophenyl)-2-(2-(2-thienyl)-ethylamino)-acetamides and process for producing them |
FR2779726B1 (fr) * | 1998-06-15 | 2001-05-18 | Sanofi Sa | Forme polymorphe de l'hydrogenosulfate de clopidogrel |
US7074928B2 (en) * | 2002-01-11 | 2006-07-11 | Teva Pharmaceutical Industries, Ltd. | Polymorphs of clopidogrel hydrogensulfate |
AU2003285841A1 (en) * | 2002-11-28 | 2004-06-18 | Anpharm Przedsiebiorstwo Farmaceutyczne S.A. | A process for the preparation of crystalline form 1 or clopidogrel hydrogen sulfate |
EP1651646B1 (en) * | 2003-08-04 | 2012-05-09 | Wockhardt Limited | A novel process for the manufacture of (+)-(s)-clopidogrel bisulfate form-i |
DE10337773A1 (de) * | 2003-08-13 | 2005-03-24 | Krka Tovarna Zdravil, D.D. | Kristallisation von festen Formen von Clopidogrel-Additionssalzen |
US7629465B2 (en) * | 2004-03-05 | 2009-12-08 | Ipca Laboratories Ltd. | Industrial process for preparation of Clopidogrel hydrogen sulphate |
US7999106B2 (en) * | 2004-04-19 | 2011-08-16 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Processes for the preparation of clopidogrel hydrogen sulfate polymorphic form I |
AU2005327776A1 (en) * | 2005-02-15 | 2006-08-24 | Usv Limited | Rapid resolution process for clopidogrel base and a process for preparation of Clopidogrel bisulfate polymorph - Form I |
EP1693375A1 (en) * | 2005-02-21 | 2006-08-23 | KRKA, tovarna zdravil, d.d., Novo mesto | Process for preparing clopidrogel hydrogen sulfate of form I |
US7772398B2 (en) * | 2005-03-11 | 2010-08-10 | Dr. Reddy's Laboratories, Inc. | Process for making crystalline form I of clopidogrel hydrogen sulphate |
KR20090013794A (ko) * | 2006-04-27 | 2009-02-05 | 인드-스위프트 래버러토리즈 리미티드 | 클로피도그렐 히드로겐 설페이트의 다형태의 제조방법 |
WO2008004249A2 (en) * | 2006-07-04 | 2008-01-10 | Msn Laboratories Limited | An improved process for the preparation of clopidogrel and its pharmaceutically acceptable salts |
US20090247569A1 (en) * | 2006-08-03 | 2009-10-01 | Claude Singer | Process for Preparing Clopidogrel Bisulphate |
-
2007
- 2007-03-23 PL PL382055A patent/PL382055A1/pl not_active Application Discontinuation
-
2008
- 2008-03-19 EP EP08741764A patent/EP2139902A1/en not_active Withdrawn
- 2008-03-19 US US12/531,888 patent/US20100216999A1/en not_active Abandoned
- 2008-03-19 WO PCT/PL2008/000023 patent/WO2008118030A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2008118030A1 (en) | 2008-10-02 |
EP2139902A1 (en) | 2010-01-06 |
US20100216999A1 (en) | 2010-08-26 |
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Legal Events
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REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |