PL1696812T3 - Tissue ablation with irreversible electroporation - Google Patents

Tissue ablation with irreversible electroporation

Info

Publication number
PL1696812T3
PL1696812T3 PL04815540T PL04815540T PL1696812T3 PL 1696812 T3 PL1696812 T3 PL 1696812T3 PL 04815540 T PL04815540 T PL 04815540T PL 04815540 T PL04815540 T PL 04815540T PL 1696812 T3 PL1696812 T3 PL 1696812T3
Authority
PL
Poland
Prior art keywords
tissue ablation
irreversible electroporation
electroporation
irreversible
ablation
Prior art date
Application number
PL04815540T
Other languages
Polish (pl)
Inventor
Rafael Davalos
Boris Rubinsky
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of PL1696812T3 publication Critical patent/PL1696812T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/1206—Generators therefor
    • A61B18/1233—Generators therefor with circuits for assuring patient safety
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1477—Needle-like probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577—Ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00613—Irreversible electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636—Sensing and controlling the application of energy
    • A61B2018/00696—Controlled or regulated parameters
    • A61B2018/00714—Temperature
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636—Sensing and controlling the application of energy
    • A61B2018/00696—Controlled or regulated parameters
    • A61B2018/00761—Duration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636—Sensing and controlling the application of energy
    • A61B2018/00773—Sensed parameters
    • A61B2018/00827—Current
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B2018/1405—Electrodes having a specific shape
    • A61B2018/1425—Needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0472—Structure-related aspects
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Otolaryngology (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Plasma & Fusion (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Electrotherapy Devices (AREA)
  • Surgical Instruments (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
PL04815540T 2003-12-24 2004-12-21 Tissue ablation with irreversible electroporation PL1696812T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53258803P 2003-12-24 2003-12-24
PCT/US2004/043477 WO2005065284A2 (en) 2003-12-24 2004-12-21 Tissue ablation with irreversible electroporation
EP04815540.2A EP1696812B1 (en) 2003-12-24 2004-12-21 Tissue ablation with irreversible electroporation

Publications (1)

Publication Number Publication Date
PL1696812T3 true PL1696812T3 (en) 2015-12-31

Family

ID=34748811

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04815540T PL1696812T3 (en) 2003-12-24 2004-12-21 Tissue ablation with irreversible electroporation

Country Status (9)

Country Link
US (8) US20050171574A1 (en)
EP (2) EP1696812B1 (en)
JP (2) JP5138229B2 (en)
AU (2) AU2004311842C1 (en)
CA (1) CA2550846C (en)
DK (1) DK1696812T3 (en)
ES (2) ES2729378T3 (en)
PL (1) PL1696812T3 (en)
WO (1) WO2005065284A2 (en)

Families Citing this family (299)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6355425B1 (en) * 1999-03-26 2002-03-12 Billups-Rothenberg, Inc. Mutations associated with iron disorders
US6300108B1 (en) * 1999-07-21 2001-10-09 The Regents Of The University Of California Controlled electroporation and mass transfer across cell membranes
US8251986B2 (en) * 2000-08-17 2012-08-28 Angiodynamics, Inc. Method of destroying tissue cells by eletroporation
US6892099B2 (en) 2001-02-08 2005-05-10 Minnesota Medical Physics, Llc Apparatus and method for reducing subcutaneous fat deposits, virtual face lift and body sculpturing by electroporation
US6795728B2 (en) 2001-08-17 2004-09-21 Minnesota Medical Physics, Llc Apparatus and method for reducing subcutaneous fat deposits by electroporation
US6697670B2 (en) 2001-08-17 2004-02-24 Minnesota Medical Physics, Llc Apparatus and method for reducing subcutaneous fat deposits by electroporation with improved comfort of patients
USRE42016E1 (en) 2001-08-13 2010-12-28 Angiodynamics, Inc. Apparatus and method for the treatment of benign prostatic hyperplasia
US6994706B2 (en) 2001-08-13 2006-02-07 Minnesota Medical Physics, Llc Apparatus and method for treatment of benign prostatic hyperplasia
US7130697B2 (en) * 2002-08-13 2006-10-31 Minnesota Medical Physics Llc Apparatus and method for the treatment of benign prostatic hyperplasia
US9308043B2 (en) 2002-04-08 2016-04-12 Medtronic Ardian Luxembourg S.A.R.L. Methods for monopolar renal neuromodulation
US7162303B2 (en) 2002-04-08 2007-01-09 Ardian, Inc. Renal nerve stimulation method and apparatus for treatment of patients
US7853333B2 (en) 2002-04-08 2010-12-14 Ardian, Inc. Methods and apparatus for multi-vessel renal neuromodulation
US20140018880A1 (en) 2002-04-08 2014-01-16 Medtronic Ardian Luxembourg S.A.R.L. Methods for monopolar renal neuromodulation
US9636174B2 (en) 2002-04-08 2017-05-02 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
US20070135875A1 (en) 2002-04-08 2007-06-14 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US8131371B2 (en) 2002-04-08 2012-03-06 Ardian, Inc. Methods and apparatus for monopolar renal neuromodulation
US8347891B2 (en) 2002-04-08 2013-01-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen
US8774922B2 (en) 2002-04-08 2014-07-08 Medtronic Ardian Luxembourg S.A.R.L. Catheter apparatuses having expandable balloons for renal neuromodulation and associated systems and methods
US8774913B2 (en) 2002-04-08 2014-07-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for intravasculary-induced neuromodulation
US8150519B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods and apparatus for bilateral renal neuromodulation
US20070129761A1 (en) 2002-04-08 2007-06-07 Ardian, Inc. Methods for treating heart arrhythmia
US7653438B2 (en) 2002-04-08 2010-01-26 Ardian, Inc. Methods and apparatus for renal neuromodulation
US20080213331A1 (en) 2002-04-08 2008-09-04 Ardian, Inc. Methods and devices for renal nerve blocking
US7756583B2 (en) 2002-04-08 2010-07-13 Ardian, Inc. Methods and apparatus for intravascularly-induced neuromodulation
US8145316B2 (en) 2002-04-08 2012-03-27 Ardian, Inc. Methods and apparatus for renal neuromodulation
US8145317B2 (en) 2002-04-08 2012-03-27 Ardian, Inc. Methods for renal neuromodulation
US8150520B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods for catheter-based renal denervation
US7620451B2 (en) 2005-12-29 2009-11-17 Ardian, Inc. Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach
US7617005B2 (en) 2002-04-08 2009-11-10 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US9308044B2 (en) 2002-04-08 2016-04-12 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
US6978174B2 (en) 2002-04-08 2005-12-20 Ardian, Inc. Methods and devices for renal nerve blocking
AU2004311842C1 (en) 2003-12-24 2011-01-06 The Regents Of The University Of California Tissue ablation with irreversible electroporation
US8298222B2 (en) * 2003-12-24 2012-10-30 The Regents Of The University Of California Electroporation to deliver chemotherapeutics and enhance tumor regression
JP4443278B2 (en) * 2004-03-26 2010-03-31 テルモ株式会社 Catheter with expansion body
US7937143B2 (en) * 2004-11-02 2011-05-03 Ardian, Inc. Methods and apparatus for inducing controlled renal neuromodulation
US7601149B2 (en) 2005-03-07 2009-10-13 Boston Scientific Scimed, Inc. Apparatus for switching nominal and attenuated power between ablation probes
US20060264752A1 (en) * 2005-04-27 2006-11-23 The Regents Of The University Of California Electroporation controlled with real time imaging
US20060293731A1 (en) * 2005-06-24 2006-12-28 Boris Rubinsky Methods and systems for treating tumors using electroporation
US20060293730A1 (en) 2005-06-24 2006-12-28 Boris Rubinsky Methods and systems for treating restenosis sites using electroporation
US8114070B2 (en) * 2005-06-24 2012-02-14 Angiodynamics, Inc. Methods and systems for treating BPH using electroporation
US20060293725A1 (en) * 2005-06-24 2006-12-28 Boris Rubinsky Methods and systems for treating fatty tissue sites using electroporation
WO2007004833A2 (en) * 2005-06-30 2007-01-11 Lg Electronics Inc. Method and apparatus for encoding and decoding an audio signal
US7824870B2 (en) * 2006-01-03 2010-11-02 Alcon, Inc. System for dissociation and removal of proteinaceous tissue
US20070156135A1 (en) * 2006-01-03 2007-07-05 Boris Rubinsky System and methods for treating atrial fibrillation using electroporation
AU2007221182B2 (en) * 2006-02-24 2011-11-03 Eastern Virginia Medical School Nanosecond pulsed electric fields cause melanomas to self-destruct
CN101553180B (en) 2006-09-14 2013-08-07 拉热尔技术有限公司 Device for destruction of cancer cells
WO2008048620A2 (en) 2006-10-16 2008-04-24 The Regents Of The University Of California Gels with predetermined conductivity used in irreversible electroporation of tissue
US20080132884A1 (en) * 2006-12-01 2008-06-05 Boris Rubinsky Systems for treating tissue sites using electroporation
EP2091453B1 (en) * 2006-12-08 2010-05-05 Koninklijke Philips Electronics N.V. A system, method, computer-readable medium, and use for planning combined therapy
US20080200911A1 (en) * 2007-02-15 2008-08-21 Long Gary L Electrical ablation apparatus, system, and method
US7655004B2 (en) 2007-02-15 2010-02-02 Ethicon Endo-Surgery, Inc. Electroporation ablation apparatus, system, and method
US20080200762A1 (en) * 2007-02-16 2008-08-21 Stokes Michael J Flexible endoscope shapelock
US7815662B2 (en) 2007-03-08 2010-10-19 Ethicon Endo-Surgery, Inc. Surgical suture anchors and deployment device
EP2142005B1 (en) * 2007-03-29 2010-08-18 Novozymes A/S Process for treating vegetable material with an enzyme
US8075572B2 (en) 2007-04-26 2011-12-13 Ethicon Endo-Surgery, Inc. Surgical suturing apparatus
US8100922B2 (en) * 2007-04-27 2012-01-24 Ethicon Endo-Surgery, Inc. Curved needle suturing tool
WO2009009398A1 (en) 2007-07-06 2009-01-15 Tsunami Medtech, Llc Medical system and method of use
US20090054728A1 (en) * 2007-08-21 2009-02-26 Trusty Robert M Manipulatable guide system and methods for natural orifice translumenal endoscopic surgery
US8197470B2 (en) 2007-08-23 2012-06-12 Aegea Medical, Inc. Uterine therapy device and method
US8579897B2 (en) 2007-11-21 2013-11-12 Ethicon Endo-Surgery, Inc. Bipolar forceps
US8262655B2 (en) 2007-11-21 2012-09-11 Ethicon Endo-Surgery, Inc. Bipolar forceps
US8673623B2 (en) * 2007-08-31 2014-03-18 Board Of Regents, The University Of Texas System Apparatus for performing magnetic electroporation
US8568410B2 (en) 2007-08-31 2013-10-29 Ethicon Endo-Surgery, Inc. Electrical ablation surgical instruments
WO2009036457A1 (en) * 2007-09-14 2009-03-19 Lazure Technologies, Llc Multi-layer electrode ablation probe and related methods
US20090076500A1 (en) * 2007-09-14 2009-03-19 Lazure Technologies, Llc Multi-tine probe and treatment by activation of opposing tines
WO2009036472A1 (en) 2007-09-14 2009-03-19 Lazure Technologies, Llc Prostate cancer ablation
US20160184006A1 (en) * 2007-09-14 2016-06-30 Lazure Scientific, Inc. Ablation probe with deployable electrodes
US20090087900A1 (en) * 2007-09-28 2009-04-02 Kent Davey Apparatus for Performing Electrodistention on Algae Cells
US20090112059A1 (en) 2007-10-31 2009-04-30 Nobis Rudolph H Apparatus and methods for closing a gastrotomy
US8480657B2 (en) 2007-10-31 2013-07-09 Ethicon Endo-Surgery, Inc. Detachable distal overtube section and methods for forming a sealable opening in the wall of an organ
US9707403B2 (en) 2007-12-12 2017-07-18 Neuro Code Tech Holdings, Llc Rapid destruction of malignant tumors by excitotoxicity and osmotic-shock medical tactics
US20090177219A1 (en) * 2008-01-03 2009-07-09 Conlon Sean P Flexible tissue-penetration instrument with blunt tip assembly and methods for penetrating tissue
US8656930B2 (en) 2008-01-10 2014-02-25 Neuro-Code Tech Holdings, LLC Method and system for processing cancer cell electrical signals for medical therapy
US8262680B2 (en) 2008-03-10 2012-09-11 Ethicon Endo-Surgery, Inc. Anastomotic device
WO2009121009A2 (en) * 2008-03-27 2009-10-01 The Regents Of The University Of California Irreversible electroporation device for use in attenuating neointimal
US20100004623A1 (en) * 2008-03-27 2010-01-07 Angiodynamics, Inc. Method for Treatment of Complications Associated with Arteriovenous Grafts and Fistulas Using Electroporation
US8831738B2 (en) 2008-04-17 2014-09-09 Neuro Code Tech Holdings, Llc System and method to elicit apoptosis in malignant tumor cells for medical treatment
US8992517B2 (en) 2008-04-29 2015-03-31 Virginia Tech Intellectual Properties Inc. Irreversible electroporation to treat aberrant cell masses
US10245098B2 (en) 2008-04-29 2019-04-02 Virginia Tech Intellectual Properties, Inc. Acute blood-brain barrier disruption using electrical energy based therapy
US11254926B2 (en) 2008-04-29 2022-02-22 Virginia Tech Intellectual Properties, Inc. Devices and methods for high frequency electroporation
US9867652B2 (en) 2008-04-29 2018-01-16 Virginia Tech Intellectual Properties, Inc. Irreversible electroporation using tissue vasculature to treat aberrant cell masses or create tissue scaffolds
US10238447B2 (en) 2008-04-29 2019-03-26 Virginia Tech Intellectual Properties, Inc. System and method for ablating a tissue site by electroporation with real-time monitoring of treatment progress
US11272979B2 (en) 2008-04-29 2022-03-15 Virginia Tech Intellectual Properties, Inc. System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies
US10117707B2 (en) 2008-04-29 2018-11-06 Virginia Tech Intellectual Properties, Inc. System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies
US20220151688A1 (en) * 2008-04-29 2022-05-19 Virginia Tech Intellectual Properties Inc. System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies
US10272178B2 (en) 2008-04-29 2019-04-30 Virginia Tech Intellectual Properties Inc. Methods for blood-brain barrier disruption using electrical energy
WO2012071526A2 (en) * 2010-11-23 2012-05-31 Virginia Tech Intellectual Properties, Inc. Irreversible electroporation using tissue vasculature to treat aberrant cell masses or create tissue scaffolds
WO2009134876A1 (en) 2008-04-29 2009-11-05 Virginia Tech Intellectual Properties, Inc. Irreversible electroporation to create tissue scaffolds
US10702326B2 (en) 2011-07-15 2020-07-07 Virginia Tech Intellectual Properties, Inc. Device and method for electroporation based treatment of stenosis of a tubular body part
US9198733B2 (en) 2008-04-29 2015-12-01 Virginia Tech Intellectual Properties, Inc. Treatment planning for electroporation-based therapies
US8926606B2 (en) 2009-04-09 2015-01-06 Virginia Tech Intellectual Properties, Inc. Integration of very short electric pulses for minimally to noninvasive electroporation
US9283051B2 (en) 2008-04-29 2016-03-15 Virginia Tech Intellectual Properties, Inc. System and method for estimating a treatment volume for administering electrical-energy based therapies
US20090281559A1 (en) * 2008-05-06 2009-11-12 Ethicon Endo-Surgery, Inc. Anastomosis patch
WO2009137609A2 (en) 2008-05-06 2009-11-12 Cellutions, Inc. Apparatus and systems for treating a human tissue condition
WO2009137800A2 (en) * 2008-05-09 2009-11-12 Angiodynamics, Inc. Electroporation device and method
US8317806B2 (en) 2008-05-30 2012-11-27 Ethicon Endo-Surgery, Inc. Endoscopic suturing tension controlling and indication devices
US8070759B2 (en) 2008-05-30 2011-12-06 Ethicon Endo-Surgery, Inc. Surgical fastening device
US8771260B2 (en) 2008-05-30 2014-07-08 Ethicon Endo-Surgery, Inc. Actuating and articulating surgical device
US8652150B2 (en) * 2008-05-30 2014-02-18 Ethicon Endo-Surgery, Inc. Multifunction surgical device
US8679003B2 (en) 2008-05-30 2014-03-25 Ethicon Endo-Surgery, Inc. Surgical device and endoscope including same
US8114072B2 (en) 2008-05-30 2012-02-14 Ethicon Endo-Surgery, Inc. Electrical ablation device
US8906035B2 (en) 2008-06-04 2014-12-09 Ethicon Endo-Surgery, Inc. Endoscopic drop off bag
US8403926B2 (en) 2008-06-05 2013-03-26 Ethicon Endo-Surgery, Inc. Manually articulating devices
US9173704B2 (en) 2008-06-20 2015-11-03 Angiodynamics, Inc. Device and method for the ablation of fibrin sheath formation on a venous catheter
US9681909B2 (en) * 2008-06-23 2017-06-20 Angiodynamics, Inc. Treatment devices and methods
US8361112B2 (en) 2008-06-27 2013-01-29 Ethicon Endo-Surgery, Inc. Surgical suture arrangement
US20100010294A1 (en) * 2008-07-10 2010-01-14 Ethicon Endo-Surgery, Inc. Temporarily positionable medical devices
US8888792B2 (en) 2008-07-14 2014-11-18 Ethicon Endo-Surgery, Inc. Tissue apposition clip application devices and methods
US8262563B2 (en) 2008-07-14 2012-09-11 Ethicon Endo-Surgery, Inc. Endoscopic translumenal articulatable steerable overtube
US20100010298A1 (en) * 2008-07-14 2010-01-14 Ethicon Endo-Surgery, Inc. Endoscopic translumenal flexible overtube
US8221411B2 (en) * 2008-07-28 2012-07-17 Medtronic, Inc. Systems and methods for cardiac tissue electroporation ablation
US8211125B2 (en) 2008-08-15 2012-07-03 Ethicon Endo-Surgery, Inc. Sterile appliance delivery device for endoscopic procedures
US8529563B2 (en) * 2008-08-25 2013-09-10 Ethicon Endo-Surgery, Inc. Electrical ablation devices
US8241204B2 (en) 2008-08-29 2012-08-14 Ethicon Endo-Surgery, Inc. Articulating end cap
US8480689B2 (en) 2008-09-02 2013-07-09 Ethicon Endo-Surgery, Inc. Suturing device
US8409200B2 (en) 2008-09-03 2013-04-02 Ethicon Endo-Surgery, Inc. Surgical grasping device
US20100056862A1 (en) * 2008-09-03 2010-03-04 Ethicon Endo-Surgery, Inc. Access needle for natural orifice translumenal endoscopic surgery
US8114119B2 (en) 2008-09-09 2012-02-14 Ethicon Endo-Surgery, Inc. Surgical grasping device
US20100100093A1 (en) * 2008-09-16 2010-04-22 Lazure Technologies, Llc. System and method for controlled tissue heating for destruction of cancerous cells
US20100114680A1 (en) * 2008-10-01 2010-05-06 Ryan Steelberg On-site barcode advertising
US8337394B2 (en) 2008-10-01 2012-12-25 Ethicon Endo-Surgery, Inc. Overtube with expandable tip
US8157834B2 (en) 2008-11-25 2012-04-17 Ethicon Endo-Surgery, Inc. Rotational coupling device for surgical instrument with flexible actuators
US8172772B2 (en) * 2008-12-11 2012-05-08 Ethicon Endo-Surgery, Inc. Specimen retrieval device
US20100152725A1 (en) * 2008-12-12 2010-06-17 Angiodynamics, Inc. Method and system for tissue treatment utilizing irreversible electroporation and thermal track coagulation
US8652129B2 (en) 2008-12-31 2014-02-18 Medtronic Ardian Luxembourg S.A.R.L. Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation
US8828031B2 (en) 2009-01-12 2014-09-09 Ethicon Endo-Surgery, Inc. Apparatus for forming an anastomosis
US8361066B2 (en) * 2009-01-12 2013-01-29 Ethicon Endo-Surgery, Inc. Electrical ablation devices
US8753335B2 (en) 2009-01-23 2014-06-17 Angiodynamics, Inc. Therapeutic energy delivery device with rotational mechanism
US9226772B2 (en) 2009-01-30 2016-01-05 Ethicon Endo-Surgery, Inc. Surgical device
US8252057B2 (en) 2009-01-30 2012-08-28 Ethicon Endo-Surgery, Inc. Surgical access device
US20100198248A1 (en) * 2009-02-02 2010-08-05 Ethicon Endo-Surgery, Inc. Surgical dissector
US8037591B2 (en) 2009-02-02 2011-10-18 Ethicon Endo-Surgery, Inc. Surgical scissors
US11284931B2 (en) 2009-02-03 2022-03-29 Tsunami Medtech, Llc Medical systems and methods for ablating and absorbing tissue
WO2010093692A2 (en) * 2009-02-10 2010-08-19 Hobbs Eamonn P Irreversible electroporation and tissue regeneration
US20110004096A1 (en) * 2009-07-06 2011-01-06 California Institute Of Technology Electromagnetic cellular tomography
US9599591B2 (en) 2009-03-06 2017-03-21 California Institute Of Technology Low cost, portable sensor for molecular assays
US20100240995A1 (en) * 2009-03-17 2010-09-23 Bioelectromed Corp. System and method for treating tumors
US20100249700A1 (en) * 2009-03-27 2010-09-30 Ethicon Endo-Surgery, Inc. Surgical instruments for in vivo assembly
JP2012521863A (en) * 2009-03-31 2012-09-20 アンジオダイナミツクス・インコーポレイテツド System and method for treatment area estimation and interactive patient treatment planning of treatment devices
US11382681B2 (en) 2009-04-09 2022-07-12 Virginia Tech Intellectual Properties, Inc. Device and methods for delivery of high frequency electrical pulses for non-thermal ablation
US11638603B2 (en) 2009-04-09 2023-05-02 Virginia Tech Intellectual Properties, Inc. Selective modulation of intracellular effects of cells using pulsed electric fields
US8728139B2 (en) 2009-04-16 2014-05-20 Lazure Technologies, Llc System and method for energy delivery to a tissue using an electrode array
IT1394143B1 (en) * 2009-05-04 2012-05-25 Igea S P A DEVICE FOR REVERSIBLE ELECTROPORATION ACTING TO CURE CELLULAR APOPTOSIS
USD630321S1 (en) 2009-05-08 2011-01-04 Angio Dynamics, Inc. Probe handle
WO2014143014A1 (en) 2013-03-15 2014-09-18 Triagenics, Llc Therapeutic tooth bud ablation
US10022202B2 (en) 2013-03-15 2018-07-17 Triagenics, Llc Therapeutic tooth bud ablation
US9402693B2 (en) * 2009-05-11 2016-08-02 Triagenics, Llc Therapeutic tooth bud ablation
WO2010138919A2 (en) * 2009-05-28 2010-12-02 Angiodynamics, Inc. System and method for synchronizing energy delivery to the cardiac rhythm
US9895189B2 (en) 2009-06-19 2018-02-20 Angiodynamics, Inc. Methods of sterilization and treating infection using irreversible electroporation
WO2011028937A1 (en) * 2009-09-04 2011-03-10 The Regents Of The University Of California Extracellular matrix material created using non-thermal irreversible electroporation
WO2011032149A2 (en) * 2009-09-14 2011-03-17 Board Of Regents, The University Of Texas System Bipolar solid state marx generator
US9474565B2 (en) 2009-09-22 2016-10-25 Mederi Therapeutics, Inc. Systems and methods for treating tissue with radiofrequency energy
US9750563B2 (en) 2009-09-22 2017-09-05 Mederi Therapeutics, Inc. Systems and methods for treating tissue with radiofrequency energy
US9775664B2 (en) 2009-09-22 2017-10-03 Mederi Therapeutics, Inc. Systems and methods for treating tissue with radiofrequency energy
US10386990B2 (en) 2009-09-22 2019-08-20 Mederi Rf, Llc Systems and methods for treating tissue with radiofrequency energy
US20110093009A1 (en) * 2009-10-16 2011-04-21 Ethicon Endo-Surgery, Inc. Otomy closure device
US20110098704A1 (en) 2009-10-28 2011-04-28 Ethicon Endo-Surgery, Inc. Electrical ablation devices
US8608652B2 (en) 2009-11-05 2013-12-17 Ethicon Endo-Surgery, Inc. Vaginal entry surgical devices, kit, system, and method
US20110118729A1 (en) * 2009-11-13 2011-05-19 Alcon Research, Ltd High-intensity pulsed electric field vitrectomy apparatus with load detection
US20110118734A1 (en) * 2009-11-16 2011-05-19 Alcon Research, Ltd. Capsularhexis device using pulsed electric fields
US20110118732A1 (en) 2009-11-19 2011-05-19 The Regents Of The University Of California Controlled irreversible electroporation
US20110135626A1 (en) * 2009-12-08 2011-06-09 Alcon Research, Ltd. Localized Chemical Lysis of Ocular Tissue
US20110144562A1 (en) * 2009-12-14 2011-06-16 Alcon Research, Ltd. Localized Pharmacological Treatment of Ocular Tissue Using High-Intensity Pulsed Electrical Fields
US20110144641A1 (en) * 2009-12-15 2011-06-16 Alcon Research, Ltd. High-Intensity Pulsed Electric Field Vitrectomy Apparatus
US8353487B2 (en) 2009-12-17 2013-01-15 Ethicon Endo-Surgery, Inc. User interface support devices for endoscopic surgical instruments
US8496574B2 (en) 2009-12-17 2013-07-30 Ethicon Endo-Surgery, Inc. Selectively positionable camera for surgical guide tube assembly
US9028483B2 (en) 2009-12-18 2015-05-12 Ethicon Endo-Surgery, Inc. Surgical instrument comprising an electrode
US8506564B2 (en) 2009-12-18 2013-08-13 Ethicon Endo-Surgery, Inc. Surgical instrument comprising an electrode
US9005198B2 (en) 2010-01-29 2015-04-14 Ethicon Endo-Surgery, Inc. Surgical instrument comprising an electrode
US20110202052A1 (en) * 2010-02-12 2011-08-18 Daniel Gelbart System for treating benign prostatic hyperplasia
KR20130108067A (en) 2010-04-09 2013-10-02 베식스 바스큘라 인코포레이티드 Power generating and control apparatus for the treatment of tissue
GB201006841D0 (en) * 2010-04-26 2010-06-09 Thomsen Lars Method, device and system for targetted cell lysis
US9526911B1 (en) 2010-04-27 2016-12-27 Lazure Scientific, Inc. Immune mediated cancer cell destruction, systems and methods
US8546979B2 (en) 2010-08-11 2013-10-01 Alcon Research, Ltd. Self-matching pulse generator with adjustable pulse width and pulse frequency
US9943353B2 (en) 2013-03-15 2018-04-17 Tsunami Medtech, Llc Medical system and method of use
US8652130B2 (en) * 2010-08-18 2014-02-18 Invasix Ltd. Method and device for soft tissue ablation
EP2627274B1 (en) 2010-10-13 2022-12-14 AngioDynamics, Inc. System for electrically ablating tissue of a patient
CN107007348B (en) 2010-10-25 2019-05-31 美敦力Af卢森堡有限责任公司 For the estimation of nerve modulation treatment and device, the system and method for feedback
EP2637590B1 (en) 2010-11-09 2022-04-13 Aegea Medical, Inc. Positioning apparatus for delivering vapor to the uterus
WO2012082688A1 (en) 2010-12-15 2012-06-21 Old Dominion University Research Foundation Electroporation-induced electrosensitization
WO2012088149A2 (en) 2010-12-20 2012-06-28 Virginia Tech Intellectual Properties, Inc. High-frequency electroporation for cancer therapy
US10092291B2 (en) 2011-01-25 2018-10-09 Ethicon Endo-Surgery, Inc. Surgical instrument with selectively rigidizable features
US9314620B2 (en) 2011-02-28 2016-04-19 Ethicon Endo-Surgery, Inc. Electrical ablation devices and methods
US9233241B2 (en) 2011-02-28 2016-01-12 Ethicon Endo-Surgery, Inc. Electrical ablation devices and methods
US9254169B2 (en) 2011-02-28 2016-02-09 Ethicon Endo-Surgery, Inc. Electrical ablation devices and methods
WO2012125785A1 (en) 2011-03-17 2012-09-20 Ethicon Endo-Surgery, Inc. Hand held surgical device for manipulating an internal magnet assembly within a patient
US10307167B2 (en) 2012-12-14 2019-06-04 Corquest Medical, Inc. Assembly and method for left atrial appendage occlusion
US10813630B2 (en) 2011-08-09 2020-10-27 Corquest Medical, Inc. Closure system for atrial wall
US10314594B2 (en) 2012-12-14 2019-06-11 Corquest Medical, Inc. Assembly and method for left atrial appendage occlusion
US9078665B2 (en) 2011-09-28 2015-07-14 Angiodynamics, Inc. Multiple treatment zone ablation probe
CN104135960B (en) 2011-10-07 2017-06-06 埃杰亚医疗公司 A kind of uterine therapy device
US9414881B2 (en) 2012-02-08 2016-08-16 Angiodynamics, Inc. System and method for increasing a target zone for electrical ablation
US8986199B2 (en) 2012-02-17 2015-03-24 Ethicon Endo-Surgery, Inc. Apparatus and methods for cleaning the lens of an endoscope
US9750568B2 (en) 2012-03-08 2017-09-05 Medtronic Ardian Luxembourg S.A.R.L. Ovarian neuromodulation and associated systems and methods
AU2013229776B2 (en) 2012-03-08 2016-12-15 Medtronic Af Luxembourg S.A.R.L. Biomarker sampling in the context of neuromodulation devices and associated systems
ES2629952T3 (en) * 2012-05-07 2017-08-16 The University Of Ottawa Procedure to control the size of solid state nanopores
US9427255B2 (en) 2012-05-14 2016-08-30 Ethicon Endo-Surgery, Inc. Apparatus for introducing a steerable camera assembly into a patient
SG11201407873RA (en) * 2012-05-29 2014-12-30 Autonomix Medical Inc Endoscopic sympathectomy systems and methods
US9078662B2 (en) 2012-07-03 2015-07-14 Ethicon Endo-Surgery, Inc. Endoscopic cap electrode and method for using the same
US9545290B2 (en) 2012-07-30 2017-01-17 Ethicon Endo-Surgery, Inc. Needle probe guide
US9572623B2 (en) 2012-08-02 2017-02-21 Ethicon Endo-Surgery, Inc. Reusable electrode and disposable sheath
US10314649B2 (en) 2012-08-02 2019-06-11 Ethicon Endo-Surgery, Inc. Flexible expandable electrode and method of intraluminal delivery of pulsed power
US9861802B2 (en) 2012-08-09 2018-01-09 University Of Iowa Research Foundation Catheters, catheter systems, and methods for puncturing through a tissue structure
US9277957B2 (en) 2012-08-15 2016-03-08 Ethicon Endo-Surgery, Inc. Electrosurgical devices and methods
US9113911B2 (en) * 2012-09-06 2015-08-25 Medtronic Ablation Frontiers Llc Ablation device and method for electroporating tissue cells
US20140110296A1 (en) 2012-10-19 2014-04-24 Medtronic Ardian Luxembourg S.A.R.L. Packaging for Catheter Treatment Devices and Associated Devices, Systems, and Methods
US10080907B1 (en) 2012-10-26 2018-09-25 University Of South Florida Systems and methods for controlling the spatial distribution of an electromagnetic field
US20140142689A1 (en) 2012-11-21 2014-05-22 Didier De Canniere Device and method of treating heart valve malfunction
US10098527B2 (en) 2013-02-27 2018-10-16 Ethidcon Endo-Surgery, Inc. System for performing a minimally invasive surgical procedure
US9438264B1 (en) 2015-09-10 2016-09-06 Realtek Semiconductor Corp. High-speed capacitive digital-to-analog converter and method thereof
US20140378963A1 (en) * 2013-06-20 2014-12-25 Gyrus Acmi, Inc., D.B.A. Olympus Surgical Technologies America Treatment of uterine fibroids by arterial ablation
US10154869B2 (en) 2013-08-02 2018-12-18 Gary M. Onik System and method for creating radio-frequency energy electrical membrane breakdown for tissue ablation
EP3030185B1 (en) 2013-08-06 2023-05-10 Memorial Sloan Kettering Cancer Center System and computer-accessible medium for in-vivo tissue ablation and/or damage
US10154873B2 (en) 2013-11-14 2018-12-18 Rm2 Technology Llc Methods, systems, and apparatuses for delivery of electrolysis products
US9566443B2 (en) 2013-11-26 2017-02-14 Corquest Medical, Inc. System for treating heart valve malfunction including mitral regurgitation
EA201691073A1 (en) 2013-12-05 2016-12-30 РФЕМБ ХОЛДИНГС, ЭлЭлСи CANCER IMMUNOTHERAPY USING RADIO-FREQUENCY ELECTRICAL BREAKDOWN MEMBRANE (RF-EMB)
US10314648B2 (en) 2013-12-13 2019-06-11 The Trustees of the Universoty of Pennsylvania Coaxial ablation probe and method and system for real-time monitoring of ablation therapy
WO2015103574A1 (en) 2014-01-06 2015-07-09 Iowa Approach Inc. Apparatus and methods for renal denervation ablation
US10166321B2 (en) 2014-01-09 2019-01-01 Angiodynamics, Inc. High-flow port and infusion needle systems
US9980766B1 (en) 2014-03-28 2018-05-29 Medtronic Ardian Luxembourg S.A.R.L. Methods and systems for renal neuromodulation
US10194980B1 (en) 2014-03-28 2019-02-05 Medtronic Ardian Luxembourg S.A.R.L. Methods for catheter-based renal neuromodulation
US10194979B1 (en) 2014-03-28 2019-02-05 Medtronic Ardian Luxembourg S.A.R.L. Methods for catheter-based renal neuromodulation
US20150289923A1 (en) * 2014-04-14 2015-10-15 Virginia Tech Intellectual Properties, Inc. Treatment planning for electrical-energy based therapies based on cell characteristics
EP4238521A3 (en) 2014-05-07 2023-11-29 Farapulse, Inc. Methods and apparatus for selective tissue ablation
CN106715682A (en) 2014-05-12 2017-05-24 弗吉尼亚暨州立大学知识产权公司 Selective modulation of intracellular effects of cells using pulsed electric fields
EP3145426B1 (en) 2014-05-22 2023-03-22 Aegea Medical, Inc. Apparatus for delivering vapor to the uterus
WO2015179666A1 (en) * 2014-05-22 2015-11-26 Aegea Medical Inc. Systems and methods for performing endometrial ablation
WO2015192027A1 (en) 2014-06-12 2015-12-17 Iowa Approach Inc. Method and apparatus for rapid and selective transurethral tissue ablation
WO2015192018A1 (en) 2014-06-12 2015-12-17 Iowa Approach Inc. Method and apparatus for rapid and selective tissue ablation with cooling
EP3206613B1 (en) 2014-10-14 2019-07-03 Farapulse, Inc. Apparatus for rapid and safe pulmonary vein cardiac ablation
US10835311B2 (en) 2014-10-24 2020-11-17 Northwestern University Electroporation apparatus and method of using same for ablation of an arbitrary volume
US10842626B2 (en) 2014-12-09 2020-11-24 Didier De Canniere Intracardiac device to correct mitral regurgitation
US10694972B2 (en) 2014-12-15 2020-06-30 Virginia Tech Intellectual Properties, Inc. Devices, systems, and methods for real-time monitoring of electrophysical effects during tissue treatment
US10271893B2 (en) 2014-12-15 2019-04-30 Medtronic Ablation Frontiers Llc Timed energy delivery
KR102128856B1 (en) 2015-01-30 2020-07-02 알에프이엠비 홀딩스, 엘엘씨 system for ablating undesirable soft tissue in a living subject using radio frequency electrical membrane breakdown
WO2016126905A2 (en) * 2015-02-04 2016-08-11 Rfemb Holdings, Llc Radio-frequency electrical membrane breakdown for reducing restenosis
WO2016130385A2 (en) * 2015-02-10 2016-08-18 George Mbella Ekema Tissue ablation by rapid and sustained alteration in membrane potential
US20180071014A1 (en) * 2015-04-10 2018-03-15 Angiodynamics, Inc. System and Methods for Irreversible Electroporation with Thermally Controlled Electrodes
EP3288471A1 (en) * 2015-05-01 2018-03-07 Inter Science GmbH Methods, systems, and apparatuses for tissue ablation using pulse shape designs
US20160361109A1 (en) * 2015-06-11 2016-12-15 Massachusetts Institute Of Technology Methods for inducing electroporation and tissue ablation
US11154238B2 (en) 2015-08-07 2021-10-26 Electroceuticals, Llc Systems, methods and apparatuses for providing bioelectronic neurocode-based therapies to mammals
AU2016335755B2 (en) 2015-10-07 2021-07-01 Mayo Foundation For Medical Education And Research Electroporation for obesity or diabetes treatment
US20170189097A1 (en) 2016-01-05 2017-07-06 Iowa Approach Inc. Systems, apparatuses and methods for delivery of ablative energy to tissue
US10130423B1 (en) 2017-07-06 2018-11-20 Farapulse, Inc. Systems, devices, and methods for focal ablation
US10660702B2 (en) 2016-01-05 2020-05-26 Farapulse, Inc. Systems, devices, and methods for focal ablation
US10172673B2 (en) 2016-01-05 2019-01-08 Farapulse, Inc. Systems devices, and methods for delivery of pulsed electric field ablative energy to endocardial tissue
US11612426B2 (en) 2016-01-15 2023-03-28 Immunsys, Inc. Immunologic treatment of cancer
EP3416551B1 (en) 2016-02-19 2022-10-12 Aegea Medical Inc. Apparatus for determining the integrity of a bodily cavity
WO2017218734A1 (en) 2016-06-16 2017-12-21 Iowa Approach, Inc. Systems, apparatuses, and methods for guide wire delivery
CN109788979B (en) 2016-06-27 2022-04-19 盖能适治疗股份有限公司 Generator and catheter with electrodes and method for treating a lung passageway
JP7158820B2 (en) * 2016-10-26 2022-10-24 ロレアル Electroporation device and method for controlling electroporation device
US10905492B2 (en) 2016-11-17 2021-02-02 Angiodynamics, Inc. Techniques for irreversible electroporation using a single-pole tine-style internal device communicating with an external surface electrode
US11717337B2 (en) * 2016-11-29 2023-08-08 St. Jude Medical, Cardiology Division, Inc. Electroporation systems and catheters for electroporation systems
EP3576839B1 (en) 2017-04-10 2022-10-26 St. Jude Medical, Cardiology Division, Inc. Electroporation system and method of preconditioning tissue for electroporation therapy
US9987081B1 (en) 2017-04-27 2018-06-05 Iowa Approach, Inc. Systems, devices, and methods for signal generation
US10617867B2 (en) 2017-04-28 2020-04-14 Farapulse, Inc. Systems, devices, and methods for delivery of pulsed electric field ablative energy to esophageal tissue
SE541651C2 (en) 2017-07-28 2019-11-19 Scandinavian Chemotech Ab An electrode device and a needle electrode for use in delivery of electrical pulses to a desired tissue of a mammal
CN115844523A (en) 2017-09-12 2023-03-28 波士顿科学医学有限公司 Systems, devices, and methods for ventricular focal ablation
US11045648B2 (en) 2017-11-14 2021-06-29 Boston Scientific Scimed, Inc. Irreversible electroporation through a combination of substance injection and electrical field application
US11607537B2 (en) 2017-12-05 2023-03-21 Virginia Tech Intellectual Properties, Inc. Method for treating neurological disorders, including tumors, with electroporation
JP2021508533A (en) 2017-12-26 2021-03-11 ギャラリー，インコーポレイテッド Optimizing energy delivery for a variety of applications
CN111615371B (en) 2018-01-23 2024-02-27 波士顿科学国际有限公司 Enhanced needle array and treatment for tumor ablation
US11311329B2 (en) 2018-03-13 2022-04-26 Virginia Tech Intellectual Properties, Inc. Treatment planning for immunotherapy based treatments using non-thermal ablation techniques
US11925405B2 (en) 2018-03-13 2024-03-12 Virginia Tech Intellectual Properties, Inc. Treatment planning system for immunotherapy enhancement via non-thermal ablation
JP7043317B2 (en) * 2018-03-29 2022-03-29 富士フイルムヘルスケア株式会社 Medical system
CN112118798A (en) 2018-05-07 2020-12-22 法拉普尔赛股份有限公司 Systems, devices, and methods for filtering high voltage noise induced by pulsed electric field ablation
JP7399881B2 (en) 2018-05-07 2023-12-18 ファラパルス，インコーポレイテッド epicardial ablation catheter
CN115836908A (en) 2018-05-07 2023-03-24 波士顿科学医学有限公司 Systems, devices, and methods for delivering ablation energy to tissue
CN108830017B (en) * 2018-07-05 2022-06-24 上海美杰医疗科技有限公司 Radio frequency heating temperature field prediction system based on individual impedance
CN112955088A (en) 2018-09-20 2021-06-11 法拉普尔赛股份有限公司 Systems, devices, and methods for delivering pulsed electric field ablation energy to endocardial tissue
ES2949058T3 (en) * 2018-11-05 2023-09-25 Region Hovedstaden V/Herlev Hospital A set of electrodes to improve the distribution of the electric field
WO2020150255A1 (en) 2019-01-14 2020-07-23 Cryoelectric Science Ltd. Methods, systems, and apparatuses for cryosurgery, coldsurgery, and electrolysis
JP2022524979A (en) 2019-03-01 2022-05-11 ランパート ヘルス リミテッド ライアビリティー カンパニー A pharmaceutical composition that combines immunological methods and chemotherapy for the treatment of cancer
EP3937810A1 (en) 2019-03-15 2022-01-19 Boston Scientific Scimed, Inc. Spatially multiplexed waveform for selective cell ablation
EP3937812A1 (en) 2019-03-15 2022-01-19 Boston Scientific Scimed Inc. Waveform generator and control for selective cell ablation
JP7401555B2 (en) 2019-03-15 2023-12-19 ボストン サイエンティフィック サイムド，インコーポレイテッド Time-multiplexed waveforms for selective cell ablation
EP3979938A4 (en) 2019-06-06 2023-06-28 TriAgenics, Inc. Ablation probe systems
US11950835B2 (en) 2019-06-28 2024-04-09 Virginia Tech Intellectual Properties, Inc. Cycled pulsing to mitigate thermal damage for multi-electrode irreversible electroporation therapy
US10625080B1 (en) 2019-09-17 2020-04-21 Farapulse, Inc. Systems, apparatuses, and methods for detecting ectopic electrocardiogram signals during pulsed electric field ablation
US11931094B2 (en) 2019-10-15 2024-03-19 Boston Scientific Scimed, Inc. Control system and user interface for an ablation system
US11497541B2 (en) 2019-11-20 2022-11-15 Boston Scientific Scimed, Inc. Systems, apparatuses, and methods for protecting electronic components from high power noise induced by high voltage pulses
US11065047B2 (en) 2019-11-20 2021-07-20 Farapulse, Inc. Systems, apparatuses, and methods for protecting electronic components from high power noise induced by high voltage pulses
US10842572B1 (en) 2019-11-25 2020-11-24 Farapulse, Inc. Methods, systems, and apparatuses for tracking ablation devices and generating lesion lines
US11540877B2 (en) 2019-12-03 2023-01-03 Biosense Webster (Israel) Ltd. Pulse generator for irreversible electroporation
US11660135B2 (en) 2019-12-05 2023-05-30 Biosense Webster (Israel) Ltd. Generating and interleaving of irreversible-electroporation and radiofrequnecy ablation (IRE/RFA) waveforms
US11903638B2 (en) 2019-12-11 2024-02-20 Biosense Webster (Israel) Ltd. Regulating delivery of irreversible electroporation pulses according to transferred energy
US11707320B2 (en) * 2019-12-24 2023-07-25 Biosense Webster (Israel) Ltd. Irreversible electroporation (IRE) based on field, contact force and time
US11583332B2 (en) 2019-12-24 2023-02-21 Biosense Webster (Israel) Ltd. Combined cardiac pacing and irreversible electroporation (IRE) treatment
US11794004B2 (en) 2020-06-10 2023-10-24 Biosense Webster (Israel) Ltd. Electroporation with cooling
US11819265B2 (en) 2020-07-28 2023-11-21 Biosense Webster (Israel) Ltd. Cautious irreversible-electroporation (IRE) protocol for avoiding bubble generation
US11532082B2 (en) 2020-08-31 2022-12-20 Biosense Webster (Israel) Ltd. Real-time correction of anatomical maps
US11911096B2 (en) 2020-12-17 2024-02-27 Biosense Webster (Israel) Ltd. Detecting contact and proximity between ablation electrodes by sensing changes in voltage morphology of non-activated electrodes
KR20230145407A (en) 2021-02-12 2023-10-17 램파트 헬스, 엘.엘.씨. Therapeutic compositions and methods combining multiple immunotherapies and cancer vaccines for the treatment of cancer
JP2024509644A (en) 2021-04-07 2024-03-04 ビーティーエル メディカル デベロップメント エー．エス． Pulsed field ablation device and method
US20220361944A1 (en) 2021-05-17 2022-11-17 Boston Scientific Scimed, Inc. Energy Delivery System, Method and Device
IL309432A (en) 2021-07-06 2024-02-01 Btl Medical Dev A S Pulsed field ablation device and method
WO2023097113A1 (en) 2021-11-29 2023-06-01 Boston Scientific Scimed, Inc. Bipolar needle with adjustable electrode for geometrically controlled thermal ablation of biological tissue
WO2023161796A1 (en) * 2022-02-23 2023-08-31 Cochlear Limited Adaptive electroporation
EP4342515A1 (en) 2022-09-23 2024-03-27 IGEA S.p.A. Improved electroporation device

Family Cites Families (153)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1653819A (en) 1926-08-07 1927-12-27 Northcott Ephraim Electrotherapeutical apparatus
DE863111C (en) 1951-07-03 1953-01-15 Walter Hallegger Instrument for transcutaneous and subcutaneous heating and iontophoresis and method of its use
US4016886A (en) * 1974-11-26 1977-04-12 The United States Of America As Represented By The United States Energy Research And Development Administration Method for localizing heating in tumor tissue
US4407943A (en) * 1976-12-16 1983-10-04 Millipore Corporation Immobilized antibody or antigen for immunoassay
CH617590A5 (en) * 1977-05-27 1980-06-13 Carba Ag
DE2800039C2 (en) * 1978-01-02 1984-06-20 Horst Dr.Med. 6700 Ludwigshafen Kief Acupuncture device
US5385544A (en) 1992-08-12 1995-01-31 Vidamed, Inc. BPH ablation method and apparatus
US5370675A (en) * 1992-08-12 1994-12-06 Vidamed, Inc. Medical probe device and method
GB8408529D0 (en) * 1984-04-03 1984-05-16 Health Lab Service Board Concentration of biological particles
US4946793A (en) * 1986-05-09 1990-08-07 Electropore, Inc. Impedance matching for instrumentation which electrically alters vesicle membranes
US5098843A (en) * 1987-06-04 1992-03-24 Calvin Noel M Apparatus for the high efficiency transformation of living cells
WO1989006555A1 (en) * 1988-01-21 1989-07-27 Massachusetts Institute Of Technology Transport of molecules across tissue using electroporation
US5389069A (en) * 1988-01-21 1995-02-14 Massachusetts Institute Of Technology Method and apparatus for in vivo electroporation of remote cells and tissue
US5749847A (en) 1988-01-21 1998-05-12 Massachusetts Institute Of Technology Delivery of nucleotides into organisms by electroporation
EP0346513A1 (en) * 1988-06-15 1989-12-20 Etama Ag Assembly for electrotherapy
ES2012944A6 (en) 1989-01-09 1990-04-16 Tomas Justribo Jose Ramon A device for the administration of medication by iontopheresis for local - regional treatment.
CS275292B2 (en) * 1989-02-22 1992-02-19 Cvut Fakulta Elektrotechnick Private rehabilitation apparatus with ion transcutaneous acceleration
DE4000893A1 (en) 1990-01-15 1991-07-18 Bosch Gmbh Robert Multichannel appts. for electro-simulation - provides several current circuits for patient with electrodes applying pulse signals
US5134070A (en) * 1990-06-04 1992-07-28 Casnig Dael R Method and device for cell cultivation on electrodes
US5193537A (en) * 1990-06-12 1993-03-16 Zmd Corporation Method and apparatus for transcutaneous electrical cardiac pacing
US5052391A (en) * 1990-10-22 1991-10-01 R.F.P., Inc. High frequency high intensity transcutaneous electrical nerve stimulator and method of treatment
US5990095A (en) 1991-07-03 1999-11-23 Hyal Pharmaceutical Corporation Use of hyaluronic acid and forms to prevent arterial restenosis
US5173158A (en) * 1991-07-22 1992-12-22 Schmukler Robert E Apparatus and methods for electroporation and electrofusion
US5328451A (en) * 1991-08-15 1994-07-12 Board Of Regents, The University Of Texas System Iontophoretic device and method for killing bacteria and other microbes
US5425752A (en) * 1991-11-25 1995-06-20 Vu'nguyen; Dung D. Method of direct electrical myostimulation using acupuncture needles
US6210402B1 (en) * 1995-11-22 2001-04-03 Arthrocare Corporation Methods for electrosurgical dermatological treatment
US6500173B2 (en) 1992-01-07 2002-12-31 Ronald A. Underwood Methods for electrosurgical spine surgery
US6132419A (en) 1992-05-22 2000-10-17 Genetronics, Inc. Electroporetic gene and drug therapy
US5318563A (en) * 1992-06-04 1994-06-07 Valley Forge Scientific Corporation Bipolar RF generator
US5273525A (en) 1992-08-13 1993-12-28 Btx Inc. Injection and electroporation apparatus for drug and gene delivery
US5634899A (en) * 1993-08-20 1997-06-03 Cortrak Medical, Inc. Simultaneous cardiac pacing and local drug delivery method
US5807306A (en) 1992-11-09 1998-09-15 Cortrak Medical, Inc. Polymer matrix drug delivery apparatus
GB9226376D0 (en) * 1992-12-18 1993-02-10 British Tech Group Tomography
EP0631514A4 (en) * 1993-02-02 1995-04-26 Vidamed Inc Transurethral needle ablation device and method.
US5792187A (en) * 1993-02-22 1998-08-11 Angeion Corporation Neuro-stimulation to control pain during cardioversion defibrillation
US5403311A (en) * 1993-03-29 1995-04-04 Boston Scientific Corporation Electro-coagulation and ablation and other electrotherapeutic treatments of body tissue
FR2703253B1 (en) 1993-03-30 1995-06-23 Centre Nat Rech Scient APPLICATOR OF ELECTRIC PULSES FOR TREATING BIOLOGICAL TISSUES.
US5702359A (en) 1995-06-06 1997-12-30 Genetronics, Inc. Needle electrodes for mediated delivery of drugs and genes
US5439440A (en) * 1993-04-01 1995-08-08 Genetronics, Inc. Electroporation system with voltage control feedback for clinical applications
US6832996B2 (en) * 1995-06-07 2004-12-21 Arthrocare Corporation Electrosurgical systems and methods for treating tissue
US5464437A (en) 1993-07-08 1995-11-07 Urologix, Inc. Benign prostatic hyperplasia treatment catheter with urethral cooling
US5533999A (en) * 1993-08-23 1996-07-09 Refractec, Inc. Method and apparatus for modifications of visual acuity by thermal means
JP3054319B2 (en) * 1994-03-04 2000-06-19 矢崎総業株式会社 Waterproof rubber stopper and manufacturing method thereof
US5458625A (en) * 1994-05-04 1995-10-17 Kendall; Donald E. Transcutaneous nerve stimulation device and method for using same
US5836905A (en) 1994-06-20 1998-11-17 Lemelson; Jerome H. Apparatus and methods for gene therapy
JPH11505435A (en) * 1995-01-17 1999-05-21 ヘールライン・クリストフ Balloon catheter for preventing restenosis of blood vessels after angioplasty and method for constructing the balloon catheter
US5720921A (en) * 1995-03-10 1998-02-24 Entremed, Inc. Flow electroporation chamber and method
US5810762A (en) * 1995-04-10 1998-09-22 Genetronics, Inc. Electroporation system with voltage control feedback for clinical applications
US6041252A (en) * 1995-06-07 2000-03-21 Ichor Medical Systems Inc. Drug delivery system and method
US6607529B1 (en) * 1995-06-19 2003-08-19 Medtronic Vidamed, Inc. Electrosurgical device
US5919142A (en) * 1995-06-22 1999-07-06 Btg International Limited Electrical impedance tomography method and apparatus
US5983131A (en) 1995-08-11 1999-11-09 Massachusetts Institute Of Technology Apparatus and method for electroporation of tissue
EP0776678A1 (en) * 1995-11-30 1997-06-04 Hewlett-Packard Company System for administering transcutaneous cardiac pacing with transcutaneous electrical nerve stimuli
US6010613A (en) * 1995-12-08 2000-01-04 Cyto Pulse Sciences, Inc. Method of treating materials with pulsed electrical fields
US5718246A (en) * 1996-01-03 1998-02-17 Preferential, Inc. Preferential induction of electrically mediated cell death from applied pulses
US6090106A (en) 1996-01-09 2000-07-18 Gyrus Medical Limited Electrosurgical instrument
US6016452A (en) * 1996-03-19 2000-01-18 Kasevich; Raymond S. Dynamic heating method and radio frequency thermal treatment
US5778894A (en) * 1996-04-18 1998-07-14 Elizabeth Arden Co. Method for reducing human body cellulite by treatment with pulsed electromagnetic energy
SE509241C2 (en) 1996-07-18 1998-12-21 Radinvent Ab Devices for electrodynamic radiation therapy of tumor diseases
US6102885A (en) * 1996-08-08 2000-08-15 Bass; Lawrence S. Device for suction-assisted lipectomy and method of using same
US6106521A (en) * 1996-08-16 2000-08-22 United States Surgical Corporation Apparatus for thermal treatment of tissue
US5991697A (en) 1996-12-31 1999-11-23 The Regents Of The University Of California Method and apparatus for optical Doppler tomographic imaging of fluid flow velocity in highly scattering media
WO1998033451A1 (en) * 1997-02-04 1998-08-06 National Aeronautics And Space Administration Multimodality instrument for tissue characterization
JPH10243947A (en) * 1997-03-04 1998-09-14 Olympus Optical Co Ltd High-frequency device
US5873849A (en) * 1997-04-24 1999-02-23 Ichor Medical Systems, Inc. Electrodes and electrode arrays for generating electroporation inducing electrical fields
US6085115A (en) * 1997-05-22 2000-07-04 Massachusetts Institite Of Technology Biopotential measurement including electroporation of tissue surface
US5978704A (en) 1997-06-03 1999-11-02 Uab Research Foundation Method and apparatus for treating cardiac arrhythmia
US6216034B1 (en) * 1997-08-01 2001-04-10 Genetronics, Inc. Method of programming an array of needle electrodes for electroporation therapy of tissue
US6055453A (en) * 1997-08-01 2000-04-25 Genetronics, Inc. Apparatus for addressing needle array electrodes for electroporation therapy
EP1003847A4 (en) 1997-09-04 2005-04-06 Science Res Lab Inc Cell separation using electric fields
US5999847A (en) 1997-10-21 1999-12-07 Elstrom; John A. Apparatus and method for delivery of surgical and therapeutic agents
CA2318488A1 (en) * 1997-10-24 1999-05-06 Children's Medical Center Corporation Methods for promoting cell transfection in vivo
US6009347A (en) 1998-01-27 1999-12-28 Genetronics, Inc. Electroporation apparatus with connective electrode template
US6208893B1 (en) * 1998-01-27 2001-03-27 Genetronics, Inc. Electroporation apparatus with connective electrode template
US6440127B2 (en) * 1998-02-11 2002-08-27 Cosman Company, Inc. Method for performing intraurethral radio-frequency urethral enlargement
CA2229528A1 (en) * 1998-02-13 1999-08-13 Shailesh Mehta Apparatus and method for analyzing particles
SE513814C2 (en) * 1998-03-31 2000-11-06 Aditus Medical Ab Device for the treatment of diseases with electric fields
US6219577B1 (en) * 1998-04-14 2001-04-17 Global Vascular Concepts, Inc. Iontophoresis, electroporation and combination catheters for local drug delivery to arteries and other body tissues
US6159163A (en) 1998-05-07 2000-12-12 Cedars-Sinai Medical Center System for attenuating pain during bone marrow aspiration and method
AU3973599A (en) * 1998-05-08 1999-11-29 Genetronics, Inc. Electrically induced vessel vasodilation
EP1100579B1 (en) * 1998-07-13 2015-09-02 Inovio Pharmaceuticals, Inc. Skin and muscle-targeted gene therapy by pulsed electrical field
US6212433B1 (en) * 1998-07-28 2001-04-03 Radiotherapeutics Corporation Method for treating tumors near the surface of an organ
ATE241933T1 (en) 1998-09-30 2003-06-15 Cygnus Therapeutic Systems METHOD AND DEVICE FOR PREDICTING PHYSIOLOGICAL MEASUREMENT VALUES
EP1124939B1 (en) 1998-10-08 2003-04-23 AstraZeneca AB Microfabricated cell injector
US6611706B2 (en) 1998-11-09 2003-08-26 Transpharma Ltd. Monopolar and bipolar current application for transdermal drug delivery and analyte extraction
EP1131011B1 (en) * 1998-11-16 2005-04-13 United States Surgical Corporation Apparatus for thermal treatment of tissue
US6090016A (en) * 1998-11-18 2000-07-18 Kuo; Hai Pin Collapsible treader with enhanced stability
US6351674B2 (en) * 1998-11-23 2002-02-26 Synaptic Corporation Method for inducing electroanesthesia using high frequency, high intensity transcutaneous electrical nerve stimulation
US6477410B1 (en) * 2000-05-31 2002-11-05 Biophoretic Therapeutic Systems, Llc Electrokinetic delivery of medicaments
US6261831B1 (en) * 1999-03-26 2001-07-17 The United States Of America As Represented By The Secretary Of The Air Force Ultra-wide band RF-enhanced chemotherapy for cancer treatmeat
US6738663B2 (en) * 1999-04-09 2004-05-18 Oncostim, A Minnesota Corporation Implantable device and method for the electrical treatment of cancer
US6627421B1 (en) * 1999-04-13 2003-09-30 Imarx Therapeutics, Inc. Methods and systems for applying multi-mode energy to biological samples
US6387671B1 (en) 1999-07-21 2002-05-14 The Regents Of The University Of California Electrical impedance tomography to control electroporation
US7053063B2 (en) * 1999-07-21 2006-05-30 The Regents Of The University Of California Controlled electroporation and mass transfer across cell membranes in tissue
US6403348B1 (en) * 1999-07-21 2002-06-11 The Regents Of The University Of California Controlled electroporation and mass transfer across cell membranes
US6300108B1 (en) 1999-07-21 2001-10-09 The Regents Of The University Of California Controlled electroporation and mass transfer across cell membranes
US6927049B2 (en) * 1999-07-21 2005-08-09 The Regents Of The University Of California Cell viability detection using electrical measurements
US6326177B1 (en) * 1999-08-04 2001-12-04 Eastern Virginia Medical School Of The Medical College Of Hampton Roads Method and apparatus for intracellular electro-manipulation
US20020010491A1 (en) 1999-08-04 2002-01-24 Schoenbach Karl H. Method and apparatus for intracellular electro-manipulation
US20030078499A1 (en) * 1999-08-12 2003-04-24 Eppstein Jonathan A. Microporation of tissue for delivery of bioactive agents
US6613211B1 (en) * 1999-08-27 2003-09-02 Aclara Biosciences, Inc. Capillary electrokinesis based cellular assays
JP4676042B2 (en) * 1999-10-01 2011-04-27 帝國製薬株式会社 Topical analgesic / anti-inflammatory patch containing felbinac
US6493592B1 (en) 1999-12-01 2002-12-10 Vertis Neuroscience, Inc. Percutaneous electrical therapy system with electrode position maintenance
IT1320186B1 (en) 2000-04-21 2003-11-26 Igea Srl ELECTRO-PORTATION DEVICE AND METHOD IN WHICH THE IMPULSE OF THE PULSE OR PULSES IS ESTABLISHED AUTOMATICALLY IN
US20010044596A1 (en) * 2000-05-10 2001-11-22 Ali Jaafar Apparatus and method for treatment of vascular restenosis by electroporation
KR100375657B1 (en) * 2000-06-21 2003-03-15 주식회사 몸앤맘 Apparatus and method for eliminating a fat mass in human body
US6669691B1 (en) 2000-07-18 2003-12-30 Scimed Life Systems, Inc. Epicardial myocardial revascularization and denervation methods and apparatus
WO2002032335A1 (en) 2000-07-25 2002-04-25 Rita Medical Systems Inc. Apparatus for detecting and treating tumors using localized impedance measurement
US6697670B2 (en) * 2001-08-17 2004-02-24 Minnesota Medical Physics, Llc Apparatus and method for reducing subcutaneous fat deposits by electroporation with improved comfort of patients
US6892099B2 (en) 2001-02-08 2005-05-10 Minnesota Medical Physics, Llc Apparatus and method for reducing subcutaneous fat deposits, virtual face lift and body sculpturing by electroporation
US6795728B2 (en) * 2001-08-17 2004-09-21 Minnesota Medical Physics, Llc Apparatus and method for reducing subcutaneous fat deposits by electroporation
US6702808B1 (en) * 2000-09-28 2004-03-09 Syneron Medical Ltd. Device and method for treating skin
US20020133324A1 (en) * 2000-11-03 2002-09-19 Weaver James C. Functional simulation method
US20050043726A1 (en) * 2001-03-07 2005-02-24 Mchale Anthony Patrick Device II
US20020177847A1 (en) * 2001-03-30 2002-11-28 Long Gary L. Endoscopic ablation system with flexible coupling
CA2443968A1 (en) * 2001-04-12 2002-10-24 Imperial College Innovations Limited Diagnosis and treatment of cancer: i
WO2002087692A1 (en) 2001-04-26 2002-11-07 The Procter & Gamble Company A method and apparatus for the treatment of cosmetic skin conditioins
US7160296B2 (en) * 2001-05-10 2007-01-09 Rita Medical Systems, Inc. Tissue ablation apparatus and method
JP2002360712A (en) * 2001-06-06 2002-12-17 Komatsu Powertron Kk Induction heating method for living body and apparatus therefor
US7127284B2 (en) * 2001-06-11 2006-10-24 Mercator Medsystems, Inc. Electroporation microneedle and methods for its use
US6832111B2 (en) * 2001-07-06 2004-12-14 Hosheng Tu Device for tumor diagnosis and methods thereof
US6994706B2 (en) 2001-08-13 2006-02-07 Minnesota Medical Physics, Llc Apparatus and method for treatment of benign prostatic hyperplasia
US7130697B2 (en) * 2002-08-13 2006-10-31 Minnesota Medical Physics Llc Apparatus and method for the treatment of benign prostatic hyperplasia
WO2003026525A1 (en) * 2001-09-28 2003-04-03 Rita Medical Systems, Inc. Impedance controlled tissue ablation apparatus and method
US20040243107A1 (en) 2001-10-01 2004-12-02 Macoviak John A Methods and devices for treating atrial fibrilation
FR2830767B1 (en) * 2001-10-12 2004-03-12 Optis France Sa DEVICE FOR DELIVERING DRUGS BY IONTOPHORESIS OR INTROCULAR ELECTROPORATION
WO2003035167A2 (en) 2001-10-24 2003-05-01 Power Paper Ltd Device and method for controlled delivery of active substance into the skin
US6807444B2 (en) 2001-11-05 2004-10-19 Hosheng Tu Apparatus and methods for monitoring tissue impedance
WO2003047684A2 (en) * 2001-12-04 2003-06-12 University Of Southern California Method for intracellular modifications within living cells using pulsed electric fields
EP3061492B1 (en) 2002-03-11 2018-09-19 Nitto Denko Corporation Transdermal drug delivery patch system
US6912417B1 (en) * 2002-04-05 2005-06-28 Ichor Medical Systmes, Inc. Method and apparatus for delivery of therapeutic agents
US7653438B2 (en) 2002-04-08 2010-01-26 Ardian, Inc. Methods and apparatus for renal neuromodulation
US8150520B2 (en) * 2002-04-08 2012-04-03 Ardian, Inc. Methods for catheter-based renal denervation
US6801804B2 (en) 2002-05-03 2004-10-05 Aciont, Inc. Device and method for monitoring and controlling electrical resistance at a tissue site undergoing iontophoresis
US6780178B2 (en) 2002-05-03 2004-08-24 The Board Of Trustees Of The Leland Stanford Junior University Method and apparatus for plasma-mediated thermo-electrical ablation
DE60315970T2 (en) * 2002-05-06 2008-05-21 Covidien Ag BLOOD DETECTOR FOR CHECKING AN ELECTROSURGICAL UNIT
EP1515775A4 (en) 2002-05-07 2010-03-03 Oncostim Inc Method and device for treating concer with electrical therapy in conjunction with chemotherapeutic agents and radiation therapy
AU2003227960B2 (en) * 2002-05-23 2008-10-30 Gendel Limited Ablation device
US7063698B2 (en) * 2002-06-14 2006-06-20 Ncontact Surgical, Inc. Vacuum coagulation probes
US6972014B2 (en) 2003-01-04 2005-12-06 Endocare, Inc. Open system heat exchange catheters and methods of use
US7211083B2 (en) 2003-03-17 2007-05-01 Minnesota Medical Physics, Llc Apparatus and method for hair removal by electroporation
AU2004311842C1 (en) * 2003-12-24 2011-01-06 The Regents Of The University Of California Tissue ablation with irreversible electroporation
US20050261672A1 (en) 2004-05-18 2005-11-24 Mark Deem Systems and methods for selective denervation of heart dysrhythmias
US7261710B2 (en) * 2004-10-13 2007-08-28 Medtronic, Inc. Transurethral needle ablation system
US20060264752A1 (en) 2005-04-27 2006-11-23 The Regents Of The University Of California Electroporation controlled with real time imaging
US20060293730A1 (en) 2005-06-24 2006-12-28 Boris Rubinsky Methods and systems for treating restenosis sites using electroporation
US8114070B2 (en) * 2005-06-24 2012-02-14 Angiodynamics, Inc. Methods and systems for treating BPH using electroporation
US20070156135A1 (en) * 2006-01-03 2007-07-05 Boris Rubinsky System and methods for treating atrial fibrillation using electroporation
US20080052786A1 (en) * 2006-08-24 2008-02-28 Pei-Cheng Lin Animal Model of Prostate Cancer and Use Thereof
CN101553180B (en) * 2006-09-14 2013-08-07 拉热尔技术有限公司 Device for destruction of cancer cells
US7655004B2 (en) * 2007-02-15 2010-02-02 Ethicon Endo-Surgery, Inc. Electroporation ablation apparatus, system, and method
WO2009121009A2 (en) * 2008-03-27 2009-10-01 The Regents Of The University Of California Irreversible electroporation device for use in attenuating neointimal
US10702326B2 (en) * 2011-07-15 2020-07-07 Virginia Tech Intellectual Properties, Inc. Device and method for electroporation based treatment of stenosis of a tubular body part

Also Published As

Publication number Publication date
AU2010214761A1 (en) 2010-09-23
US11033321B2 (en) 2021-06-15
EP2474281B1 (en) 2019-03-27
JP5766163B2 (en) 2015-08-19
US20070043345A1 (en) 2007-02-22
WO2005065284A2 (en) 2005-07-21
CA2550846A1 (en) 2005-07-21
AU2004311842A1 (en) 2005-07-21
US20050171523A1 (en) 2005-08-04
US9005189B2 (en) 2015-04-14
AU2004311842B2 (en) 2010-06-10
AU2004311842C1 (en) 2011-01-06
EP1696812B1 (en) 2015-07-22
JP2013046766A (en) 2013-03-07
US20050171574A1 (en) 2005-08-04
ES2543832T3 (en) 2015-08-24
CA2550846C (en) 2018-01-23
US8282631B2 (en) 2012-10-09
JP2007516792A (en) 2007-06-28
US20190046255A1 (en) 2019-02-14
US10117701B2 (en) 2018-11-06
US20120071874A1 (en) 2012-03-22
AU2010214761B2 (en) 2012-12-06
US20150173824A1 (en) 2015-06-25
WO2005065284A3 (en) 2005-11-17
EP1696812A4 (en) 2010-03-03
EP1696812A2 (en) 2006-09-06
ES2729378T3 (en) 2019-11-04
US8048067B2 (en) 2011-11-01
US20080269586A1 (en) 2008-10-30
DK1696812T3 (en) 2015-10-26
US20120277741A1 (en) 2012-11-01
EP2474281A1 (en) 2012-07-11
JP5138229B2 (en) 2013-02-06

Similar Documents

Publication Publication Date Title
PL1696812T3 (en) Tissue ablation with irreversible electroporation
EP1596746A4 (en) Cardiac ablation devices
EP1781200A4 (en) Transparent electrode for the radiofrequency ablation of tissue
EP1779763A4 (en) Endoscope and tip cover
EP1909679A4 (en) Low power tissue ablation system
IL173247A0 (en) Electrosurgical generator
EP1909674A4 (en) Electrosurgical device and methods
GB0426648D0 (en) An electrosurgical generator
EP1729657A4 (en) Tissue cutting devices and methods
GB2416699B (en) Skin rejuvenation
GB0326228D0 (en) Wing tip device
HK1101497A1 (en) Ablation catheter
GB0303797D0 (en) Blood assessment
HK1075423A1 (en) Human nosecock
ZA200603566B (en) Tissue sampling needle
GB0322342D0 (en) Skin patch
GB0309585D0 (en) Weed suppressant gel
EP1689285A4 (en) Cardiac ablation devices and methods
GB0411051D0 (en) Energy harvester
GB0701549D0 (en) Skin treatment
GB2398740B (en) Skin composition
GB0311815D0 (en) Skin treatments
GB0311816D0 (en) Skin treatments
GB2420287B (en) Skin puncturing device
GB0320763D0 (en) Skin patches