NZ702413A - Compound as wnt signaling inhibitor, composition, and use thereof - Google Patents
Compound as wnt signaling inhibitor, composition, and use thereofInfo
- Publication number
- NZ702413A NZ702413A NZ702413A NZ70241312A NZ702413A NZ 702413 A NZ702413 A NZ 702413A NZ 702413 A NZ702413 A NZ 702413A NZ 70241312 A NZ70241312 A NZ 70241312A NZ 702413 A NZ702413 A NZ 702413A
- Authority
- NZ
- New Zealand
- Prior art keywords
- compound
- alkyl
- hydrogen
- alkoxy
- cyano
- Prior art date
Links
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- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
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- A61K31/5375—1,4-Oxazines, e.g. morpholine
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
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- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
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- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Psychiatry (AREA)
- Physical Education & Sports Medicine (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Ophthalmology & Optometry (AREA)
- Gastroenterology & Hepatology (AREA)
- Psychology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
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Abstract
Description
Claims (27)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/CN2012/077032 WO2013185353A1 (en) | 2012-06-15 | 2012-06-15 | Compound as wnt signaling inhibitor, composition, and use thereof |
Publications (2)
Publication Number | Publication Date |
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NZ702413A true NZ702413A (en) | 2016-08-26 |
NZ702413B2 NZ702413B2 (en) | 2016-11-29 |
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IL236242A0 (en) | 2015-02-01 |
SG11201408237YA (en) | 2015-01-29 |
EP2861590A1 (en) | 2015-04-22 |
MX359146B (en) | 2018-09-17 |
HK1209732A1 (en) | 2016-04-08 |
IN2015DN00129A (en) | 2015-05-29 |
CN104379583A (en) | 2015-02-25 |
EP2861590A4 (en) | 2015-12-30 |
CN104379583B (en) | 2016-06-08 |
US20150119387A1 (en) | 2015-04-30 |
KR101824300B1 (en) | 2018-01-31 |
JP6081582B2 (en) | 2017-02-15 |
US9556144B2 (en) | 2017-01-31 |
BR112014031263B1 (en) | 2022-03-29 |
AU2012382875B2 (en) | 2017-04-20 |
US10087181B2 (en) | 2018-10-02 |
BR112014031263A2 (en) | 2018-04-24 |
US20170073344A1 (en) | 2017-03-16 |
JP2015523348A (en) | 2015-08-13 |
CN106188045B (en) | 2018-01-16 |
CA2875372C (en) | 2019-04-09 |
CA2875372A1 (en) | 2013-12-19 |
WO2013185353A1 (en) | 2013-12-19 |
ES2649673T3 (en) | 2018-01-15 |
IL236242B (en) | 2018-04-30 |
AU2012382875A1 (en) | 2014-12-18 |
MX2014015281A (en) | 2015-06-23 |
KR20150024826A (en) | 2015-03-09 |
EP2861590B1 (en) | 2017-10-25 |
RU2014150338A (en) | 2016-08-10 |
CN106188045A (en) | 2016-12-07 |
RU2627712C2 (en) | 2017-08-10 |
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