NZ226481A - Dideoxycytidine derivatives and pharmaceutical compositions - Google Patents

Dideoxycytidine derivatives and pharmaceutical compositions

Info

Publication number
NZ226481A
NZ226481A NZ226481A NZ22648188A NZ226481A NZ 226481 A NZ226481 A NZ 226481A NZ 226481 A NZ226481 A NZ 226481A NZ 22648188 A NZ22648188 A NZ 22648188A NZ 226481 A NZ226481 A NZ 226481A
Authority
NZ
New Zealand
Prior art keywords
dideoxycytidine
derivatives
pharmaceutical compositions
pharmaceutical
compositions
Prior art date
Application number
NZ226481A
Inventor
John Joseph Partridge
Steve Tam
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NZ226481A publication Critical patent/NZ226481A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
NZ226481A 1987-10-09 1988-10-06 Dideoxycytidine derivatives and pharmaceutical compositions NZ226481A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10722187A 1987-10-09 1987-10-09

Publications (1)

Publication Number Publication Date
NZ226481A true NZ226481A (en) 1992-01-29

Family

ID=22315505

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ226481A NZ226481A (en) 1987-10-09 1988-10-06 Dideoxycytidine derivatives and pharmaceutical compositions

Country Status (14)

Country Link
EP (1) EP0311100A3 (en)
JP (1) JPH01132597A (en)
KR (1) KR890006624A (en)
AU (1) AU2355488A (en)
DK (1) DK564088A (en)
FI (1) FI884627A (en)
HU (1) HU201090B (en)
IL (1) IL87949A0 (en)
MC (1) MC1982A1 (en)
NO (1) NO884497L (en)
NZ (1) NZ226481A (en)
PT (1) PT88716B (en)
YU (1) YU187788A (en)
ZA (1) ZA886890B (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223263A (en) * 1988-07-07 1993-06-29 Vical, Inc. Liponucleotide-containing liposomes
US6448392B1 (en) 1985-03-06 2002-09-10 Chimerix, Inc. Lipid derivatives of antiviral nucleosides: liposomal incorporation and method of use
NZ223910A (en) * 1987-03-20 1991-02-26 Bristol Myers Co 2',3'-dideoxynucleosides, process for their production and intermediates therefor
US5631370A (en) * 1988-01-20 1997-05-20 Regents Of The University Of Minnesota Optically-active isomers of dideoxycarbocyclic nucleosides
US6252060B1 (en) 1988-07-07 2001-06-26 Nexstar Pharmaceuticals, Inc. Antiviral liponucleosides: treatment of hepatitis B
US6599887B2 (en) 1988-07-07 2003-07-29 Chimerix, Inc. Methods of treating viral infections using antiviral liponucleotides
US5817638A (en) * 1988-07-07 1998-10-06 Nexstar Pharmaceuticals, Inc. Antiviral liponucleosides: treatment of hepatitis B
GB8823320D0 (en) * 1988-10-05 1988-11-09 Nycomed As Chemical compounds
WO1991006554A1 (en) * 1989-11-06 1991-05-16 Nycomed As Nucleoside derivatives
US5192764A (en) * 1991-05-30 1993-03-09 Research Foundation Of State Of N.Y. Pyrazinone n-oxide nucleosides and analogs thereof
RU2085557C1 (en) * 1991-09-30 1997-07-27 Санкио Компани Лимитед Pyrimidine nucleoside derivatives or their pharmaceutically acceptable salts and method of their synthesis
US6576636B2 (en) 1996-05-22 2003-06-10 Protarga, Inc. Method of treating a liver disorder with fatty acid-antiviral agent conjugates
JP2001524486A (en) * 1997-11-25 2001-12-04 プロタルガ,インコーポレーテッド Nucleoside-like component composition and use thereof
JP4634694B2 (en) 2001-03-23 2011-02-16 ルイトポルド・ファーマシューティカルズ・インコーポレーテッド Fatty alcohol drug complex
WO2002076402A2 (en) 2001-03-23 2002-10-03 Protarga, Inc. Fatty amine drug conjugates
JP2005519916A (en) * 2001-12-14 2005-07-07 フアーマセツト・リミテツド N4-acylcytosine nucleosides for the treatment of viral infection
US9326983B2 (en) 2013-08-01 2016-05-03 University Of Kentucky Research Foundation Compositions and methods for treating retinal degradation
JP6691922B2 (en) * 2015-02-26 2020-05-13 ユニバーシティー オブ ケンタッキー リサーチ ファウンデイションUniversity Of Kentucky Research Foundation Compositions and methods for treating retinal degeneration
US11219623B2 (en) 2015-02-26 2022-01-11 University Of Kentucky Research Foundation Inflammasome inhibition for the treatment of Parkinson's disease, Alzheimer's disease and multiple sclerosis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5943550B2 (en) * 1975-08-29 1984-10-23 田辺製薬株式会社 Process for producing unsaturated nucleosides
CA1314875C (en) * 1985-05-15 1993-03-23 George Walter Koszalka Therapeutic nucleosides
EP0342203B1 (en) * 1987-03-24 1994-07-06 Nycomed Imaging As 2',3' dideoxyribofuranoxide derivatives
EP0294113A1 (en) * 1987-05-29 1988-12-07 The Wellcome Foundation Limited Therapeutic nucleosides
US4837311A (en) * 1987-06-22 1989-06-06 Hoffman-La Roche Inc. Anti-retroviral compounds

Also Published As

Publication number Publication date
YU187788A (en) 1990-04-30
DK564088A (en) 1989-04-10
DK564088D0 (en) 1988-10-07
FI884627A (en) 1989-04-10
AU2355488A (en) 1989-04-13
EP0311100A2 (en) 1989-04-12
PT88716B (en) 1992-12-31
IL87949A0 (en) 1989-03-31
KR890006624A (en) 1989-06-14
NO884497L (en) 1989-04-10
JPH01132597A (en) 1989-05-25
HU201090B (en) 1990-09-28
MC1982A1 (en) 1989-11-23
NO884497D0 (en) 1988-10-07
EP0311100A3 (en) 1990-10-31
FI884627A0 (en) 1988-10-07
HUT47592A (en) 1989-03-28
ZA886890B (en) 1989-05-30

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