NO933699L - Sulfated polysaccharides as inhibitors of smooth muscle cell proliferation - Google Patents

Sulfated polysaccharides as inhibitors of smooth muscle cell proliferation

Info

Publication number
NO933699L
NO933699L NO933699A NO933699A NO933699L NO 933699 L NO933699 L NO 933699L NO 933699 A NO933699 A NO 933699A NO 933699 A NO933699 A NO 933699A NO 933699 L NO933699 L NO 933699L
Authority
NO
Norway
Prior art keywords
inhibitors
cell proliferation
smooth muscle
muscle cell
sulfated polysaccharides
Prior art date
Application number
NO933699A
Other languages
Norwegian (no)
Other versions
NO933699D0 (en
Inventor
H Edward Conrad
Peter Fugedi
Brian K Brandley
Lun H Lam
Roger A Laine
Original Assignee
Glycomed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glycomed Inc filed Critical Glycomed Inc
Publication of NO933699D0 publication Critical patent/NO933699D0/en
Publication of NO933699L publication Critical patent/NO933699L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078—Degradation products

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
NO933699A 1991-04-17 1993-10-14 Sulfated polysaccharides as inhibitors of smooth muscle cell proliferation NO933699L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68654091A 1991-04-17 1991-04-17
PCT/US1992/003092 WO1992018546A1 (en) 1991-04-17 1992-04-15 Sulfated polysaccharides as inhibitors of smooth muscle cell proliferation

Publications (2)

Publication Number Publication Date
NO933699D0 NO933699D0 (en) 1993-10-14
NO933699L true NO933699L (en) 1993-12-07

Family

ID=24756732

Family Applications (1)

Application Number Title Priority Date Filing Date
NO933699A NO933699L (en) 1991-04-17 1993-10-14 Sulfated polysaccharides as inhibitors of smooth muscle cell proliferation

Country Status (6)

Country Link
EP (1) EP0582665A1 (en)
JP (1) JPH06506973A (en)
AU (1) AU1902592A (en)
CA (1) CA2108569A1 (en)
NO (1) NO933699L (en)
WO (1) WO1992018546A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5811447A (en) * 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
WO1994026303A1 (en) * 1993-05-13 1994-11-24 Neorx Corporation Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells
US5888984A (en) * 1994-05-12 1999-03-30 Dermal Research Laboratories, Inc. Pharmaceutical composition of complex carbohydrates and essential oils and methods of using the same
AUPN261895A0 (en) * 1995-04-28 1995-05-18 Australian National University, The Preparation and use of sulfated oligosaccharides
AUPO556297A0 (en) 1997-03-11 1997-04-10 Australian National University, The Sulfated oligosaccharides having anticoagulant/ antithrombotic activity
AUPO888497A0 (en) * 1997-09-01 1997-09-25 Australian National University, The Use of sulfated oligosaccharides as inhibitors of cardiovascular disease
AUPO976897A0 (en) 1997-10-14 1997-11-06 Australian National University, The Use of sulfated oligosaccharides in lowering blood triglyceride levels
DE60034667T2 (en) 1999-02-01 2008-03-13 Dermal Research Laboratories, Inc. PHARMACEUTICAL COMPOSITION OF COMPLEX CARBOHYDRATES AND THEIR USE
US7879824B2 (en) 2001-07-31 2011-02-01 Dermal Research Laboratories, Inc. Methods of preventing or treating diseases and conditions using complex carbohydrates
JPWO2005092348A1 (en) * 2004-03-29 2008-02-07 敏一 中村 Heparin-like oligosaccharide-containing HGF production promoter
FR2949114B1 (en) * 2009-08-14 2011-08-26 Sanofi Aventis FGF RECEPTOR ACTIVATORY N-ACYLATED OCTASACCHARIDES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2949115B1 (en) * 2009-08-14 2012-11-02 Sanofi Aventis FGF RECEPTOR ACTIVATOR N-SULFATE OLIGOSACCHARIDES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL61201A (en) * 1979-10-05 1984-09-30 Choay Sa Oligosaccharides having no more than 8 saccharide moieties,their obtention from heparin and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
AU1902592A (en) 1992-11-17
JPH06506973A (en) 1994-08-04
CA2108569A1 (en) 1992-10-18
NO933699D0 (en) 1993-10-14
WO1992018546A1 (en) 1992-10-29
EP0582665A1 (en) 1994-02-16

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