NL7610038A - Multichambered capsule for therapeutically active substances - has chambers of different solubility with contents differing quantitatively and qualitatively - Google Patents

Multichambered capsule for therapeutically active substances - has chambers of different solubility with contents differing quantitatively and qualitatively

Info

Publication number
NL7610038A
NL7610038A NL7610038A NL7610038A NL7610038A NL 7610038 A NL7610038 A NL 7610038A NL 7610038 A NL7610038 A NL 7610038A NL 7610038 A NL7610038 A NL 7610038A NL 7610038 A NL7610038 A NL 7610038A
Authority
NL
Netherlands
Prior art keywords
capsule
same
therapeutically active
active substances
multichambered
Prior art date
Application number
NL7610038A
Other languages
Dutch (nl)
Original Assignee
Tapanahony N V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tapanahony N V filed Critical Tapanahony N V
Priority to NL7610038A priority Critical patent/NL7610038A/en
Publication of NL7610038A publication Critical patent/NL7610038A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A capsule for therapeutically active substances has a wall which is of a material soluble in the stomach or intestine, e.g. gelatine. The capsule is closed by a cover and forms a holder for the therapeutical material; the interior being divided by >=1 partition into >=2 or more compartments. The separate compartments may contain similarly active therapeutical substances or alternatively, the medicaments contained may differ in their effect. The solubility of the materials of the outer capsule and of the covers is different. Alternatively the speed at which the material dissolve may be the same. The contents of the separate compartments may be the same in quantity or they may be different. The capsule allows the same or differing materials to be released into the alimentary duct, at different intervals of time in the same or in widely differing quantities.
NL7610038A 1976-09-09 1976-09-09 Multichambered capsule for therapeutically active substances - has chambers of different solubility with contents differing quantitatively and qualitatively NL7610038A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NL7610038A NL7610038A (en) 1976-09-09 1976-09-09 Multichambered capsule for therapeutically active substances - has chambers of different solubility with contents differing quantitatively and qualitatively

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7610038A NL7610038A (en) 1976-09-09 1976-09-09 Multichambered capsule for therapeutically active substances - has chambers of different solubility with contents differing quantitatively and qualitatively

Publications (1)

Publication Number Publication Date
NL7610038A true NL7610038A (en) 1978-03-13

Family

ID=19826865

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7610038A NL7610038A (en) 1976-09-09 1976-09-09 Multichambered capsule for therapeutically active substances - has chambers of different solubility with contents differing quantitatively and qualitatively

Country Status (1)

Country Link
NL (1) NL7610038A (en)

Cited By (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0308637A1 (en) * 1987-08-21 1989-03-29 Dieter Dr. Stephan Capsules for the pharmaceutically active contents of a medicament
US5074426A (en) * 1986-11-13 1991-12-24 Warner-Lambert Company Dividable capsule
US5310555A (en) * 1992-07-24 1994-05-10 Midwestern Bio-Ag Products And Services, Inc. Oral nutritional and dietary composition
US5501857A (en) * 1992-07-24 1996-03-26 Midwestern Bio-Ag Products & Services, Inc. Oral nutritional and dietary composition
EP0804174A1 (en) * 1993-07-21 1997-11-05 The University of Kentucky Research Foundation A multicompartment hard capsule with control release properties
WO2002007710A3 (en) * 2000-07-20 2002-04-25 Mw Encap Ltd Delivery device
GB2370554A (en) * 1999-11-17 2002-07-03 Reckitt Benckiser Rigid water-soluble containers
WO2002060384A2 (en) 2001-01-30 2002-08-08 Smithkline Beecham Plc. Pharmaceutical formulation
EP1248595A1 (en) * 2000-01-20 2002-10-16 Delsys Pharmaceutical Corporation Multi-step drug dosage forms
WO2004010978A1 (en) 2002-07-25 2004-02-05 Glaxo Group Limited Multicomponent pharmaceutical dosage form
WO2005009380A2 (en) 2003-07-21 2005-02-03 Smith Kline Beecham P.L.C. Pharmaceutical formulations
WO2006055886A2 (en) 2004-11-19 2006-05-26 Smithkline Beecham Corporation Method for customized dispensing of variable dose drug combination products for individualizing of therapies
WO2009050190A2 (en) 2007-10-15 2009-04-23 Glaxo Group Limited Linkers for multipart dosage forms for release of one or more pharmaceutical compositions, and the resulting dosage forms
WO2009087483A2 (en) 2007-11-08 2009-07-16 Glaxo Group Limited Pharmaceutical formulations
US7842308B2 (en) 2001-01-30 2010-11-30 Smithkline Beecham Limited Pharmaceutical formulation
US7883721B2 (en) 2001-01-30 2011-02-08 Smithkline Beecham Limited Pharmaceutical formulation
US8147871B2 (en) 2004-03-12 2012-04-03 Capsugel Belgium Bvba Pharmaceutical formulations
US8293159B2 (en) 2007-10-15 2012-10-23 Capsugel Belgium Method and apparatus for manufacturing filled linkers
WO2013050974A1 (en) * 2011-10-06 2013-04-11 Market Demand Trading 767 Proprietary Limited A method and apparatus for manufacturing a capsule
US8440224B2 (en) 1999-07-30 2013-05-14 Capsugel Belgium Nv Multi-component pharmaceutical dosage form
US8454992B2 (en) 2007-10-15 2013-06-04 Capsugel Belgium Nv Paneled capsule shells for release of pharmaceutical compositions
WO2014162288A1 (en) 2013-04-03 2014-10-09 Binutra Incorporated Capsule with internal diaphragm
EP3028694A1 (en) * 2014-12-02 2016-06-08 Capsugel Belgium NV Dosage form articles for delayed release
WO2017062956A1 (en) * 2015-10-09 2017-04-13 Binutra Incorporated Capsule with internal diaphragm and solid ingredients
US10653622B1 (en) 2015-04-13 2020-05-19 Pharmacoustics Technologies LLC Individualized solid dosage products and a system and method for the globally integrated pharmaceutical manufacturing and its monitoring thereof

Cited By (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5074426A (en) * 1986-11-13 1991-12-24 Warner-Lambert Company Dividable capsule
EP0308637A1 (en) * 1987-08-21 1989-03-29 Dieter Dr. Stephan Capsules for the pharmaceutically active contents of a medicament
US5310555A (en) * 1992-07-24 1994-05-10 Midwestern Bio-Ag Products And Services, Inc. Oral nutritional and dietary composition
US5501857A (en) * 1992-07-24 1996-03-26 Midwestern Bio-Ag Products & Services, Inc. Oral nutritional and dietary composition
EP0804174A1 (en) * 1993-07-21 1997-11-05 The University of Kentucky Research Foundation A multicompartment hard capsule with control release properties
EP0804174A4 (en) * 1993-07-21 1998-09-09 Univ Kentucky Res Found A multicompartment hard capsule with control release properties
US8440224B2 (en) 1999-07-30 2013-05-14 Capsugel Belgium Nv Multi-component pharmaceutical dosage form
GB2370554A (en) * 1999-11-17 2002-07-03 Reckitt Benckiser Rigid water-soluble containers
GB2370554B (en) * 1999-11-17 2002-11-20 Reckitt Benckiser Rigid water-soluble containers
EP1248595A4 (en) * 2000-01-20 2006-06-14 Delsys Pharmaceutical Corp Multi-step drug dosage forms
EP1248595A1 (en) * 2000-01-20 2002-10-16 Delsys Pharmaceutical Corporation Multi-step drug dosage forms
WO2002007710A3 (en) * 2000-07-20 2002-04-25 Mw Encap Ltd Delivery device
US7842308B2 (en) 2001-01-30 2010-11-30 Smithkline Beecham Limited Pharmaceutical formulation
US7883721B2 (en) 2001-01-30 2011-02-08 Smithkline Beecham Limited Pharmaceutical formulation
US8367101B2 (en) 2001-01-30 2013-02-05 Capsugel Belgium Nv Pharmaceutical formulation
EP2366384A2 (en) 2001-01-30 2011-09-21 Pfizer Inc. Pharmaceutical formulation
WO2002060385A2 (en) 2001-01-30 2002-08-08 Smithkline Beecham Plc. Pharmaceutical formulation
WO2002060384A2 (en) 2001-01-30 2002-08-08 Smithkline Beecham Plc. Pharmaceutical formulation
US8361498B2 (en) 2001-01-30 2013-01-29 Capsugel Belgium Nv Pharmaceutical formulation
EP2366383A2 (en) 2001-01-30 2011-09-21 Pfizer Inc. Pharmaceutical formulation
EP2366382A2 (en) 2001-01-30 2011-09-21 Pfizer Inc. Pharmaceutical formulation
WO2004010978A1 (en) 2002-07-25 2004-02-05 Glaxo Group Limited Multicomponent pharmaceutical dosage form
EP2556825A1 (en) 2002-07-25 2013-02-13 Capsugel Belgium NV Multicomponent pharmaceutical dosage form
WO2005009380A2 (en) 2003-07-21 2005-02-03 Smith Kline Beecham P.L.C. Pharmaceutical formulations
US8147871B2 (en) 2004-03-12 2012-04-03 Capsugel Belgium Bvba Pharmaceutical formulations
WO2006055886A2 (en) 2004-11-19 2006-05-26 Smithkline Beecham Corporation Method for customized dispensing of variable dose drug combination products for individualizing of therapies
US8454992B2 (en) 2007-10-15 2013-06-04 Capsugel Belgium Nv Paneled capsule shells for release of pharmaceutical compositions
US8293159B2 (en) 2007-10-15 2012-10-23 Capsugel Belgium Method and apparatus for manufacturing filled linkers
EP2537506A1 (en) 2007-10-15 2012-12-26 Capsugel Belgium NV Linkers for multipart dosage forms for release of one or more parmaceutical compositions, and the resulting dosage forms
WO2009050190A2 (en) 2007-10-15 2009-04-23 Glaxo Group Limited Linkers for multipart dosage forms for release of one or more pharmaceutical compositions, and the resulting dosage forms
WO2009087483A2 (en) 2007-11-08 2009-07-16 Glaxo Group Limited Pharmaceutical formulations
AU2012320100B2 (en) * 2011-10-06 2017-01-19 Combocap, Inc. A method and apparatus for manufacturing a capsule
EP3069707A1 (en) * 2011-10-06 2016-09-21 Binutra Incorporated A method and apparatus for manufacturing a capsule
CN103987357A (en) * 2011-10-06 2014-08-13 生物胶囊药物和营养产品私人有限公司 A method and apparatus for manufacturing a capsule
CN103987357B (en) * 2011-10-06 2017-12-12 康宝卡普股份有限公司 The manufacturing method and apparatus of capsule
JP2014528319A (en) * 2011-10-06 2014-10-27 バイオ カプセル ファーマシューティカル アンド ニュートリショナルプロダクツ プロプライアタリー リミティド Method and apparatus for manufacturing capsules
JP2014528318A (en) * 2011-10-06 2014-10-27 バイオ カプセル ファーマシューティカル アンド ニュートリショナルプロダクツ プロプライアタリー リミティド Method and apparatus for manufacturing capsules
US9340004B2 (en) 2011-10-06 2016-05-17 Bio Capsule Pharmaceutical And Nutritional Products (Pty) Ltd. Method and apparatus for manufacturing a capsule
RU2622749C9 (en) * 2011-10-06 2017-08-30 Байо Кэпсьюл Фармасьютикал Энд Ньютришнал Продактс Проприетери Лимитед Method and device for manufacturing capsules
RU2622749C2 (en) * 2011-10-06 2017-06-19 Байо Кэпсьюл Фармасьютикал Энд Ньютришнал Продактс Проприетери Лимитед Method and device for manufacturing capsules
WO2013050973A1 (en) * 2011-10-06 2013-04-11 Market Demand Trading 767 Proprietary Limited A method and apparatus for manufacturing a capsule
RU2622748C2 (en) * 2011-10-06 2017-06-19 Байо Кэпсьюл Фармасьютикал Энд Ньютришнал Продактс Проприетери Лимитед Method and device for manufacturing capsules
CN104010617B (en) * 2011-10-06 2017-05-10 生物胶囊药物和营养产品私人有限公司 A method and apparatus for manufacturing a capsule
EP3069708A1 (en) * 2011-10-06 2016-09-21 Binutra Incorporated Capsule
US10046549B2 (en) 2011-10-06 2018-08-14 Combocap, Inc. Method and apparatus for manufacturing a capsule
WO2013050974A1 (en) * 2011-10-06 2013-04-11 Market Demand Trading 767 Proprietary Limited A method and apparatus for manufacturing a capsule
AU2012320099B2 (en) * 2011-10-06 2017-02-02 Combocap, Inc. A method and apparatus for manufacturing a capsule
US9456987B2 (en) 2013-04-03 2016-10-04 Binutra, Inc. Capsule with internal diaphragm
AU2014246703B2 (en) * 2013-04-03 2018-07-19 Combocap, Inc. Capsule with internal diaphragm
CN105705142A (en) * 2013-04-03 2016-06-22 比纳特拉股份有限公司 Capsule with internal diaphragm
CN105705142B (en) * 2013-04-03 2020-07-10 康宝卡普股份有限公司 Capsule with internal membrane
JP2016515607A (en) * 2013-04-03 2016-05-30 ビヌトラ インコーポレイテッド Capsule with internal partition
WO2014162288A1 (en) 2013-04-03 2014-10-09 Binutra Incorporated Capsule with internal diaphragm
WO2016087263A1 (en) * 2014-12-02 2016-06-09 Capsugel Belgium N.V. Dosage form articles for delayed release
US10555908B2 (en) 2014-12-02 2020-02-11 Capsugel Belgium Nv Dosage form articles for delayed release
EP3028694A1 (en) * 2014-12-02 2016-06-08 Capsugel Belgium NV Dosage form articles for delayed release
US10653622B1 (en) 2015-04-13 2020-05-19 Pharmacoustics Technologies LLC Individualized solid dosage products and a system and method for the globally integrated pharmaceutical manufacturing and its monitoring thereof
CN108366959A (en) * 2015-10-09 2018-08-03 科姆博盖股份有限公司 Capsule with the whole internal spacer of volume-tunable
WO2017062956A1 (en) * 2015-10-09 2017-04-13 Binutra Incorporated Capsule with internal diaphragm and solid ingredients
EP3359131A4 (en) * 2015-10-09 2019-05-01 Combocap, Inc. Capsule with internal diaphragm for improved bioavailability
EP3359130A4 (en) * 2015-10-09 2019-05-01 Combocap, Inc. Capsule with volume-adjustable internal diaphragm
US11160759B1 (en) 2015-10-09 2021-11-02 Combocap, Inc. Capsule with internal diaphragm for improved bioavailability
US20220160641A1 (en) * 2015-10-09 2022-05-26 Combocap, Inc. Capsule with internal diaphragm for improved bioavailability
US11357732B2 (en) 2015-10-09 2022-06-14 Combocap, Inc. Capsule with volume-adjustable internal diaphragm
US11478429B2 (en) 2015-10-09 2022-10-25 Combocap, Inc. Capsule with internal diaphragm and solid ingredients

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