MY157827A - Sulfonamide substituted imidazoquinolines - Google Patents

Sulfonamide substituted imidazoquinolines

Info

Publication number
MY157827A
MY157827A MYPI20042461A MYPI20042461A MY157827A MY 157827 A MY157827 A MY 157827A MY PI20042461 A MYPI20042461 A MY PI20042461A MY PI20042461 A MYPI20042461 A MY PI20042461A MY 157827 A MY157827 A MY 157827A
Authority
MY
Malaysia
Prior art keywords
sulfonamide substituted
useful
substituted imidazoquinolines
compounds
imidazoquinolines
Prior art date
Application number
MYPI20042461A
Inventor
George Walter Griesgraber
Original Assignee
3M Innovative Properties Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3M Innovative Properties Co filed Critical 3M Innovative Properties Co
Publication of MY157827A publication Critical patent/MY157827A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

IMIDAZOQUINOLINE AND TETRAHYDROIMIDAZOQUINOLINE COMPOUNDS THAT CONTAIN SULFONAMIDE FUNCTIONALITY AT THE 1-POSITION ARE USEFUL AS IMMUNE RESPONSE MODIFIERS. THE COMPOUNDS AND COMPOSITIONS OF THE INVENTION CAN INDUCE THE BIOSYNTHESIS OF VARIOUS CYTOKINES AND ARE USEFUL IN THE TREATMENT OF A VARIETY OF CONDITIONS INCLUDING VIRAL DISEASES AND NEOPLASTIC DISEASES.
MYPI20042461A 2003-06-27 2004-06-24 Sulfonamide substituted imidazoquinolines MY157827A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US48320003P 2003-06-27 2003-06-27

Publications (1)

Publication Number Publication Date
MY157827A true MY157827A (en) 2016-07-29

Family

ID=33563911

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI20042461A MY157827A (en) 2003-06-27 2004-06-24 Sulfonamide substituted imidazoquinolines

Country Status (16)

Country Link
EP (1) EP1638566A4 (en)
JP (1) JP2007521280A (en)
KR (1) KR20060035637A (en)
CN (1) CN1812789B (en)
AR (2) AR044923A1 (en)
AU (1) AU2004253929A1 (en)
BR (1) BRPI0411916A (en)
CA (1) CA2529322A1 (en)
IL (1) IL172427A0 (en)
MX (1) MXPA06000144A (en)
MY (1) MY157827A (en)
NZ (1) NZ544330A (en)
RU (1) RU2374246C2 (en)
TW (2) TW200514784A (en)
WO (2) WO2005003065A2 (en)
ZA (1) ZA200600769B (en)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040265351A1 (en) 2003-04-10 2004-12-30 Miller Richard L. Methods and compositions for enhancing immune response
JP2007502288A (en) 2003-08-12 2007-02-08 スリーエム イノベイティブ プロパティズ カンパニー Oxime-substituted imidazo-containing compounds
KR101106812B1 (en) 2003-08-27 2012-01-19 쓰리엠 이노베이티브 프로퍼티즈 컴파니 Aryloxy and Arylalkyleneoxy Substituted Imidazoquinolines
CA2537763A1 (en) 2003-09-05 2005-03-17 3M Innovative Properties Company Treatment for cd5+ b cell lymphoma
US7544697B2 (en) 2003-10-03 2009-06-09 Coley Pharmaceutical Group, Inc. Pyrazolopyridines and analogs thereof
KR20060120069A (en) 2003-10-03 2006-11-24 쓰리엠 이노베이티브 프로퍼티즈 컴파니 Pyrazolopyridines and analogs thereof
NZ546273A (en) 2003-10-03 2009-05-31 Coley Pharm Group Inc Alkoxy substituted imidazoquinolines
JP2007511535A (en) 2003-11-14 2007-05-10 スリーエム イノベイティブ プロパティズ カンパニー Hydroxylamine substituted imidazo ring compounds
US7897767B2 (en) 2003-11-14 2011-03-01 3M Innovative Properties Company Oxime substituted imidazoquinolines
RU2409576C2 (en) 2003-11-25 2011-01-20 3М Инновейтив Пропертиз Компани Systems containing imidazole ring with substitutes, and methods of obtaining said systems
WO2005055932A2 (en) * 2003-12-02 2005-06-23 3M Innovative Properties Company Therapeutic combinations and methods including irm compounds
US8802853B2 (en) 2003-12-29 2014-08-12 3M Innovative Properties Company Arylalkenyl and arylalkynyl substituted imidazoquinolines
AU2004312508A1 (en) 2003-12-30 2005-07-21 3M Innovative Properties Company Imidazoquinolinyl, imidazopyridinyl, and imidazonaphthyridinyl sulfonamides
TW200612932A (en) 2004-03-24 2006-05-01 3M Innovative Properties Co Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
WO2005123080A2 (en) 2004-06-15 2005-12-29 3M Innovative Properties Company Nitrogen-containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
WO2006009826A1 (en) 2004-06-18 2006-01-26 3M Innovative Properties Company Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
WO2006038923A2 (en) 2004-06-18 2006-04-13 3M Innovative Properties Company Aryl substituted imidazonaphthyridines
US8541438B2 (en) 2004-06-18 2013-09-24 3M Innovative Properties Company Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines
US7915281B2 (en) 2004-06-18 2011-03-29 3M Innovative Properties Company Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and method
JP5543068B2 (en) 2004-12-30 2014-07-09 スリーエム イノベイティブ プロパティズ カンパニー Chiral fused [1,2] imidazo [4,5-c] cyclic compound
WO2006073940A2 (en) * 2004-12-30 2006-07-13 3M Innovative Properties Company Multi-route administration of immune response modifier compounds
ES2392648T3 (en) 2004-12-30 2012-12-12 3M Innovative Properties Company Substituted chiral compounds containing a condensed 1,2-imidazo-4,5-c core
CA2597092A1 (en) 2005-02-04 2006-08-10 Coley Pharmaceutical Group, Inc. Aqueous gel formulations containing immune reponse modifiers
JP5122980B2 (en) 2005-02-09 2013-01-16 スリーエム イノベイティブ プロパティズ カンパニー Alkyloxy-substituted thiazoloquinolines and alkyloxy-substituted thiazolonaphthylidenes
CA2597587A1 (en) 2005-02-11 2006-08-17 Coley Pharmaceutical Group, Inc. Oxime and hydroxylamine substituted imidazo[4,5-c] ring compounds and methods
JP2008535832A (en) 2005-04-01 2008-09-04 コーリー ファーマシューティカル グループ，インコーポレイテッド Pyrazolopyridine-1,4-diamine and analogs thereof
WO2006107851A1 (en) 2005-04-01 2006-10-12 Coley Pharmaceutical Group, Inc. 1-substituted pyrazolo (3,4-c) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases
ZA200803029B (en) 2005-09-09 2009-02-25 Coley Pharm Group Inc Amide and carbamate derivatives of alkyl substituted /V-[4-(4-amino-1H-imidazo[4,5-c] quinolin-1-yl)butyl] methane-sulfonamides and methods
EA200800782A1 (en) * 2005-09-09 2008-08-29 Коли Фармасьютикал Груп, Инк. AMIDA AND CARBAMATE DERIVATIVES N- {2- [4-AMINO-2- (ETOXIMETHYL) -1H-IMIDAZOLO [4,5-c] QUINOLIN-1-IL] -1,1-DIMETHYLETHYL} METHANE SULFONAMIDE AND METHODS
AU2006292119A1 (en) * 2005-09-23 2007-03-29 3M Innovative Properties Company Method for 1H-imidazo[4,5-c]pyridines and analogs thereof
WO2007100634A2 (en) 2006-02-22 2007-09-07 3M Innovative Properties Company Immune response modifier conjugates
WO2008008432A2 (en) 2006-07-12 2008-01-17 Coley Pharmaceutical Group, Inc. Substituted chiral fused( 1,2) imidazo (4,5-c) ring compounds and methods
EP2276486B1 (en) * 2008-03-24 2013-08-28 4SC Discovery GmbH Novel substituted imidazoquinolines
MX359517B (en) 2010-08-17 2018-10-01 3M Innovative Properties Company Star Lipidated immune response modifier compound compositions, formulations, and methods.
JP6415979B2 (en) 2011-06-03 2018-10-31 スリーエム イノベイティブ プロパティズ カンパニー Hydrazino 1H-imidazoquinolin-4-amine and complexes prepared therefrom
CA2838158C (en) 2011-06-03 2019-07-16 3M Innovative Properties Company Heterobifunctional linkers with polyethylene glycol segments and immune response modifier conjugates made therefrom
WO2015092592A1 (en) 2013-12-17 2015-06-25 Pfizer Inc. Novel 3,4-disubstituted-1h-pyrrolo[2,3-b]pyridines and 4,5-disubstituted-7h-pyrrolo[2,3-c]pyridazines as lrrk2 inhibitors
CN108137586B (en) 2015-09-14 2021-04-13 辉瑞大药厂 Novel imidazo [4,5-c ] quinoline and imidazo [4,5-c ] [1,5] naphthyridine derivatives as LRRK2 inhibitors
KR20230149857A (en) 2016-07-07 2023-10-27 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 Antibody adjuvant conjugates
CA3056030A1 (en) 2017-03-10 2018-09-13 Pfizer Inc. Novel imidazo[4,5-c]quinoline derivatives as lrrk2 inhibitors
CN111132969B (en) 2017-09-06 2024-01-30 生物技术公司 Substituted imidazoquinolines as TLR7 agonists
CA3086439A1 (en) 2017-12-20 2019-06-27 3M Innovative Properties Company Amide substitued imidazo[4,5-c]quinoline compounds with a branched chain linking group for use as an immune response modifier
JP2022525594A (en) 2019-03-15 2022-05-18 ボルト バイオセラピューティクス、インコーポレーテッド Immune conjugates targeting HER2
EP4076445A1 (en) * 2019-12-20 2022-10-26 Nammi Therapeutics, Inc. Formulated and/or co-formulated liposome compositions containing toll-like receptor ("tlr") agonist prodrugs useful in the treatment of cancer and methods thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6331539B1 (en) * 1999-06-10 2001-12-18 3M Innovative Properties Company Sulfonamide and sulfamide substituted imidazoquinolines
JP2005513021A (en) * 2001-11-16 2005-05-12 スリーエム イノベイティブ プロパティズ カンパニー Methods and compositions for IRM compounds and toll-like receptor pathways
US6677349B1 (en) * 2001-12-21 2004-01-13 3M Innovative Properties Company Sulfonamide and sulfamide substituted imidazoquinolines

Also Published As

Publication number Publication date
TW200511992A (en) 2005-04-01
KR20060035637A (en) 2006-04-26
AU2004253929A1 (en) 2005-01-13
CA2529322A1 (en) 2005-01-13
TW200514784A (en) 2005-05-01
AR044923A1 (en) 2005-10-12
WO2005003065A3 (en) 2005-03-10
AR044922A1 (en) 2005-10-12
CN1812789B (en) 2010-07-14
CN1812789A (en) 2006-08-02
RU2005138915A (en) 2006-06-27
MXPA06000144A (en) 2006-04-07
RU2374246C2 (en) 2009-11-27
WO2005003064A2 (en) 2005-01-13
JP2007521280A (en) 2007-08-02
EP1638566A4 (en) 2009-03-25
WO2005003064A3 (en) 2005-03-31
IL172427A0 (en) 2006-04-10
NZ544330A (en) 2009-06-26
ZA200600769B (en) 2007-05-30
WO2005003065A2 (en) 2005-01-13
BRPI0411916A (en) 2006-08-15
EP1638566A2 (en) 2006-03-29

Similar Documents

Publication Publication Date Title
TW200514784A (en) Sulfonamide substituted imidazoquinolines
MXPA04005362A (en) Thioether substituted imidazoquinolines.
HK1086762A1 (en) Sulfonamide substituted imidazoquinolines
EE200100670A (en) Amide substituted imidazoquinolines
WO2002046192A3 (en) Thioether substituted imidazoquinolines
MXPA04005331A (en) Sulfonamido substituted imidazopyridines.
PL352257A1 (en) Imidazoquinolines substituted by urea
WO2002046194A3 (en) Substituted imidazopyridines
WO2004028539A3 (en) 1h-imidazo dimers