MXPA05002955A - Test strip and method for determining ldl cholesterol concentration from whole blood. - Google Patents

Test strip and method for determining ldl cholesterol concentration from whole blood.

Info

Publication number
MXPA05002955A
MXPA05002955A MXPA05002955A MXPA05002955A MXPA05002955A MX PA05002955 A MXPA05002955 A MX PA05002955A MX PA05002955 A MXPA05002955 A MX PA05002955A MX PA05002955 A MXPA05002955 A MX PA05002955A MX PA05002955 A MXPA05002955 A MX PA05002955A
Authority
MX
Mexico
Prior art keywords
concentration
test strip
ldl cholesterol
whole blood
panel
Prior art date
Application number
MXPA05002955A
Other languages
Spanish (es)
Inventor
Lynn Antonopoulos Gena
Original Assignee
Polymer Technology Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Polymer Technology Systems Inc filed Critical Polymer Technology Systems Inc
Publication of MXPA05002955A publication Critical patent/MXPA05002955A/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/525—Multi-layer analytical elements
    • G01N33/526—Multi-layer analytical elements the element being adapted for a specific analyte
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/044—Hyperlipemia or hypolipemia, e.g. dyslipidaemia, obesity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

A dry phase test strip (20) and method are provided for determining the concentration of LDL in whole blood or plasma. The inventive test strip (20) includes one stack (92) or panel that measures concentration of total cholesterol and another stack (94) or panel that measures concentration of the sum total of HDL, VLDL and chylomicrons ("non-LDLs"). The difference between the values just noted is equal to the concentration of LDL cholesterol. Dry phase test strips (20) of the present invention function at room temperature and all test results are produced from pseudo-endpoint reflectance measurements such that the test method need not be timed. Also disclosed is the capability for an improved lipid panel that provides concentration in a blood sample of HDL, total cholesterol and LDL cholesterol without relying upon the Friedewald equation.
MXPA05002955A 2002-09-16 2003-09-16 Test strip and method for determining ldl cholesterol concentration from whole blood. MXPA05002955A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41120902P 2002-09-16 2002-09-16
PCT/US2003/029102 WO2004025265A2 (en) 2002-09-16 2003-09-16 Test strip and method for determining ldl cholesterol concentration from whole blood

Publications (1)

Publication Number Publication Date
MXPA05002955A true MXPA05002955A (en) 2005-10-18

Family

ID=31994248

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05002955A MXPA05002955A (en) 2002-09-16 2003-09-16 Test strip and method for determining ldl cholesterol concentration from whole blood.

Country Status (6)

Country Link
EP (1) EP1540353A4 (en)
AU (1) AU2003272453A1 (en)
CA (1) CA2499058A1 (en)
MX (1) MXPA05002955A (en)
WO (1) WO2004025265A2 (en)
ZA (1) ZA200502214B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10204606C1 (en) 2002-01-18 2003-10-16 Cholestech Corp Device and method for high density lipoproteins
ATE309544T1 (en) 2002-04-09 2005-11-15 Cholestech Corp METHOD AND DEVICE FOR QUANTIFYING HIGH DENSITY LIPOPROTEIN-CHOLESTEROL
US7772007B2 (en) 2004-04-02 2010-08-10 Cholestech Corporation Assay device for direct measurement of LDL cholesterol
ATE483165T1 (en) * 2007-01-09 2010-10-15 Cholestech Corp DEVICE AND METHOD FOR MEASURING LDL-ASSOCIATED CHOLESTEROL
US8304204B2 (en) 2007-09-05 2012-11-06 Arkray, Inc. Method for measuring low-density lipoprotein (LDL) cholesterol

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5132086A (en) * 1990-02-06 1992-07-21 Chemtrak Corporation Non-instrumented cholesterol assay
US5135716A (en) * 1989-07-12 1992-08-04 Kingston Diagnostics, L.P. Direct measurement of HDL cholesterol via dry chemistry strips
US5460974A (en) * 1992-10-13 1995-10-24 Miles Inc. Method of assaying whole blood for HDL cholesterol
JP3193634B2 (en) * 1996-05-29 2001-07-30 第一化学薬品株式会社 LDL cholesterol determination method
JP3441993B2 (en) * 1999-01-27 2003-09-02 松下電器産業株式会社 Cholesterol sensor
US6524864B2 (en) * 2000-12-28 2003-02-25 Aurora L. Fernandez Decastro Test strip for simultaneous detection of a plurality of analytes

Also Published As

Publication number Publication date
ZA200502214B (en) 2006-05-31
EP1540353A2 (en) 2005-06-15
EP1540353A4 (en) 2007-01-24
CA2499058A1 (en) 2004-03-25
AU2003272453A1 (en) 2004-04-30
WO2004025265A3 (en) 2004-07-01
WO2004025265A2 (en) 2004-03-25

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