MXPA03009548A - Arilsulfonamidas como agentes antivirales. - Google Patents

Arilsulfonamidas como agentes antivirales.

Info

Publication number
MXPA03009548A
MXPA03009548A MXPA03009548A MXPA03009548A MXPA03009548A MX PA03009548 A MXPA03009548 A MX PA03009548A MX PA03009548 A MXPA03009548 A MX PA03009548A MX PA03009548 A MXPA03009548 A MX PA03009548A MX PA03009548 A MXPA03009548 A MX PA03009548A
Authority
MX
Mexico
Prior art keywords
antiviral agents
arylsulfonamides
arylsulphonamides
substituents
novel
Prior art date
Application number
MXPA03009548A
Other languages
English (en)
Inventor
Raddatz Siegfried
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10148598A external-priority patent/DE10148598A1/de
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of MXPA03009548A publication Critical patent/MXPA03009548A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Abstract

La presente invencion ser refiere a nuevas sulfonamidas de formula general (ver formula) en la que los sustituyentes R', R', R', R4 asi como A y X tienen los significados dados, asi como a procedimientos para su preparacion y a su uso como agentes antivirales, especialmente frente a citomegalovirus.
MXPA03009548A 2001-04-19 2002-04-08 Arilsulfonamidas como agentes antivirales. MXPA03009548A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10119137 2001-04-19
DE10148598A DE10148598A1 (de) 2001-04-19 2001-10-02 Neue Arylsulfonamide als antivirale Mittel
PCT/EP2002/003858 WO2002085869A1 (de) 2001-04-19 2002-04-08 Arylsulfonamide als antivirale mittel

Publications (1)

Publication Number Publication Date
MXPA03009548A true MXPA03009548A (es) 2004-05-24

Family

ID=26009118

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03009548A MXPA03009548A (es) 2001-04-19 2002-04-08 Arilsulfonamidas como agentes antivirales.

Country Status (20)

Country Link
US (1) US7115612B2 (es)
EP (1) EP1383749B1 (es)
JP (1) JP4480941B2 (es)
CN (1) CN1516695A (es)
AT (1) ATE308529T1 (es)
BG (1) BG108272A (es)
BR (1) BR0209054A (es)
CA (1) CA2444123C (es)
DE (1) DE50204780D1 (es)
EE (1) EE200300515A (es)
ES (1) ES2252455T3 (es)
HU (1) HUP0303813A3 (es)
IL (1) IL158324A0 (es)
MX (1) MXPA03009548A (es)
NO (1) NO20034667L (es)
PL (1) PL363990A1 (es)
RU (1) RU2003133750A (es)
SK (1) SK12662003A3 (es)
UY (1) UY27263A1 (es)
WO (1) WO2002085869A1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004018463A2 (en) * 2002-08-23 2004-03-04 Rigel Pharmaceuticals, Inc. Pyridyl substituted heterocycles useful for treating or preventing hcv infection
DE10319612A1 (de) 2003-05-02 2004-11-18 Bayer Healthcare Ag Substituierte Dihydrochinazoline
ES2770035T3 (es) 2003-04-11 2020-06-30 Ptc Therapeutics Inc Compuesto de ácido 1,2,4-oxadiazol benzoico y su uso para la supresión sin sentido y el tratamiento de enfermedades
DE102006009928A1 (de) * 2006-03-03 2007-09-06 Aicuris Gmbh & Co. Kg Substituierte Arylsulfonamide
MX2008012515A (es) 2006-03-30 2008-11-19 Ptc Therapeutics Inc Metodos para la produccion de proteina funcional a partir de adn que tiene una mutacion sin sentido y el tratamiento de trastornos asociados con la misma.
US20080255203A1 (en) * 2007-04-12 2008-10-16 Abbott Laboratories Heterocyclic compounds and their methods of use
EP2176249A2 (en) * 2007-07-02 2010-04-21 Boehringer Ingelheim International GmbH New chemical compounds
EP2177521A1 (en) * 2008-10-14 2010-04-21 Almirall, S.A. New 2-Amidothiadiazole Derivatives
EP2202232A1 (en) * 2008-12-26 2010-06-30 Laboratorios Almirall, S.A. 1,2,4-oxadiazole derivatives and their therapeutic use
MX2013000188A (es) * 2010-06-28 2013-01-28 Bayer Ip Gmbh Compuestos heterociclicos como pesticidas.
EP2593434A1 (en) 2010-07-16 2013-05-22 Purdue Pharma LP Pyridine compounds as sodium channel blockers
WO2013136170A1 (en) 2012-03-16 2013-09-19 Purdue Pharma L.P. Substituted pyridines as sodium channel blockers
EP2914591B1 (en) * 2012-11-03 2017-10-11 Boehringer Ingelheim International GmbH Inhibitors of cytomegalovirus
WO2014070979A1 (en) * 2012-11-03 2014-05-08 Boehringer Ingelheim International Gmbh Inhibitors of cytomegalovirus
EP2935257B1 (en) 2012-12-20 2018-02-07 Purdue Pharma LP Cyclic sulfonamides as sodium channel blockers
KR102497273B1 (ko) 2014-03-06 2023-02-07 피티씨 테라퓨틱스, 인크. 1,2,4-옥사디아졸 벤조산의 약학 조성물 및 염
US10730866B2 (en) 2014-04-07 2020-08-04 Purdue Pharma L.P. Indole derivatives and use thereof
EP3256461B1 (en) * 2015-02-13 2023-09-13 Azienda Ospedaliera Universitaria Senese Urea and sulfonamide derivatives as human helicase ddx3 inhibitors useful in the treatment of viral diseases
CA3003132A1 (en) 2015-10-30 2017-05-04 Ptc Therapeutics, Inc. Methods for treating epilepsy

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19802437A1 (de) * 1998-01-23 1999-07-29 Bayer Ag Verwendung von substituierten Sulfonamiden als anitvirale Mittel und neue Stoffe
AU765203B2 (en) * 1999-04-19 2003-09-11 Shionogi & Co., Ltd. Sulfonamide derivatives having oxadiazole rings

Also Published As

Publication number Publication date
BR0209054A (pt) 2004-04-20
NO20034667D0 (no) 2003-10-17
JP4480941B2 (ja) 2010-06-16
BG108272A (bg) 2004-10-29
EP1383749B1 (de) 2005-11-02
EE200300515A (et) 2004-02-16
HUP0303813A2 (hu) 2004-03-29
CA2444123C (en) 2010-09-21
ATE308529T1 (de) 2005-11-15
DE50204780D1 (de) 2005-12-08
US7115612B2 (en) 2006-10-03
IL158324A0 (en) 2004-05-12
US20040176374A1 (en) 2004-09-09
UY27263A1 (es) 2002-11-29
CA2444123A1 (en) 2002-10-31
HUP0303813A3 (en) 2005-05-30
WO2002085869A1 (de) 2002-10-31
CN1516695A (zh) 2004-07-28
RU2003133750A (ru) 2005-05-10
JP2004531536A (ja) 2004-10-14
EP1383749A1 (de) 2004-01-28
NO20034667L (no) 2003-12-12
PL363990A1 (en) 2004-11-29
ES2252455T3 (es) 2006-05-16
SK12662003A3 (sk) 2004-04-06

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