MX2021004386A - Novel compounds. - Google Patents

Novel compounds.

Info

Publication number
MX2021004386A
MX2021004386A MX2021004386A MX2021004386A MX2021004386A MX 2021004386 A MX2021004386 A MX 2021004386A MX 2021004386 A MX2021004386 A MX 2021004386A MX 2021004386 A MX2021004386 A MX 2021004386A MX 2021004386 A MX2021004386 A MX 2021004386A
Authority
MX
Mexico
Prior art keywords
novel compounds
formula
compound
novel
compounds
Prior art date
Application number
MX2021004386A
Other languages
Spanish (es)
Inventor
Giuseppe Alvaro
Agostino Marasco
Original Assignee
Autifony Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Autifony Therapeutics Ltd filed Critical Autifony Therapeutics Ltd
Publication of MX2021004386A publication Critical patent/MX2021004386A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • A61K31/497Non-condensed pyrazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

A compound of formula (I): (Formula (I)) and related aspects.
MX2021004386A 2018-10-16 2019-10-16 Novel compounds. MX2021004386A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18200626 2018-10-16
PCT/GB2019/052937 WO2020079422A1 (en) 2018-10-16 2019-10-16 Novel compounds

Publications (1)

Publication Number Publication Date
MX2021004386A true MX2021004386A (en) 2021-06-04

Family

ID=63878368

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021004386A MX2021004386A (en) 2018-10-16 2019-10-16 Novel compounds.

Country Status (10)

Country Link
EP (1) EP3867247A1 (en)
JP (1) JP7465868B2 (en)
KR (1) KR20210076081A (en)
AR (1) AR116713A1 (en)
AU (1) AU2019360017A1 (en)
BR (1) BR112021006940A2 (en)
IL (1) IL282096B1 (en)
MX (1) MX2021004386A (en)
TW (1) TWI827706B (en)
WO (1) WO2020079422A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021156584A1 (en) * 2020-02-06 2021-08-12 Autifony Therapeutics Limited Kv3 modulators
KR20240046538A (en) 2021-08-09 2024-04-09 얀센 파마슈티카 엔브이 Monoacylglycerol lipase modulators for use in autism spectrum disorders
CN117751119A (en) 2021-08-10 2024-03-22 奥蒂福尼疗法有限公司 Potassium channel modulators

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA019970B8 (en) 2009-12-11 2014-11-28 Отифони Терапеутикс Лимитед Imidazolidinedione derivatives
BR112013013914B1 (en) * 2010-12-06 2021-10-26 Autifony Therapeutics Limited HIDANTOIN DERIVED COMPOUNDS USEFUL AS KV3 INHIBITORS, USES OF SUCH COMPOUNDS AND PHARMACEUTICAL COMPOSITION INCLUDING THEM
WO2012168710A1 (en) 2011-06-07 2012-12-13 Autifony Therapeutics Limited Hydantoin derivates as kv3 inhibitors
GB201209986D0 (en) 2012-06-06 2012-07-18 Autifony Therapeutics Ltd Novel compounds
KR20140098850A (en) 2011-12-06 2014-08-08 오티포니 세라피틱스 리미티드 Hydantoin derivatives useful as kv3 inhibitors
BR112014028718A2 (en) 2012-05-22 2017-06-27 Autifony Therapeutics Ltd hydantoin derivatives as kv3 inhibitors
EP2852589B1 (en) 2012-05-22 2021-04-28 Autifony Therapeutics Limited Triazoles as kv3 inhibitors
WO2013182851A1 (en) 2012-06-06 2013-12-12 Autifony Therapeutics Limited Prophylaxis or treatment of diseases where a modulator of kv3.3 channels is required
GB201521751D0 (en) 2015-12-10 2016-01-27 Autifony Therapeutics Ltd Novel uses
GB201522179D0 (en) 2015-12-16 2016-01-27 Autifony Therapeutics Ltd Novel compounds
GB201613163D0 (en) 2016-07-29 2016-09-14 Autifony Therapeutics Ltd Novel compounds
US20200039970A1 (en) 2016-12-16 2020-02-06 Autifony Therapeutics Limited Hydantoin modulators of kv3 channels

Also Published As

Publication number Publication date
TW202035394A (en) 2020-10-01
EP3867247A1 (en) 2021-08-25
AR116713A1 (en) 2021-06-02
BR112021006940A2 (en) 2021-07-13
IL282096B1 (en) 2024-03-01
TWI827706B (en) 2024-01-01
WO2020079422A1 (en) 2020-04-23
IL282096A (en) 2021-05-31
AU2019360017A1 (en) 2021-04-01
KR20210076081A (en) 2021-06-23
JP2022505143A (en) 2022-01-14
JP7465868B2 (en) 2024-04-11

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