MX2015011676A - Inhibidores de leucotrieno a4 hidrolasa. - Google Patents

Inhibidores de leucotrieno a4 hidrolasa.

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Publication number
MX2015011676A
MX2015011676A MX2015011676A MX2015011676A MX2015011676A MX 2015011676 A MX2015011676 A MX 2015011676A MX 2015011676 A MX2015011676 A MX 2015011676A MX 2015011676 A MX2015011676 A MX 2015011676A MX 2015011676 A MX2015011676 A MX 2015011676A
Authority
MX
Mexico
Prior art keywords
hydrolase
leukotriene
inhibitors
methods
diseases
Prior art date
Application number
MX2015011676A
Other languages
English (en)
Inventor
William Guilford
David Davey
Original Assignee
Celtaxsys Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celtaxsys Inc filed Critical Celtaxsys Inc
Publication of MX2015011676A publication Critical patent/MX2015011676A/es

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    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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Abstract

La presente invención se orienta hacia compuestos englobados por la Formula (I), las composiciones farmacéuticas de los mismos, los métodos para inhibir el LTA-4 hidrolasa, así como métodos para el tratamiento contra una enfermedad o trastorno que se mejore por medio de la inhibición de la actividad del LTA4-h. Ejemplos no limitantes de dichas enfermedades y condiciones incluyen las enfermedades y trastornos inflamatorios y autoinmunes.
MX2015011676A 2013-03-14 2014-03-14 Inhibidores de leucotrieno a4 hidrolasa. MX2015011676A (es)

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PCT/US2014/027449 WO2014152536A2 (en) 2013-03-14 2014-03-14 Inhibitors of leukotriene a4 hydrolase

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US9822106B2 (en) 2017-11-21
US20160068522A1 (en) 2016-03-10
WO2014152536A3 (en) 2014-11-27
JP6562898B2 (ja) 2019-08-21
AU2019204753A1 (en) 2019-07-18
WO2014152536A2 (en) 2014-09-25
CA2906086A1 (en) 2014-09-25
KR20150131211A (ko) 2015-11-24

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