MX2009006795A - Compuestos que tienen tanto actividades de antagonismo de receptor de angiotensina ii como actividades activadoras de receptores activados por proliferizador de peroxisomas gamma. - Google Patents
Compuestos que tienen tanto actividades de antagonismo de receptor de angiotensina ii como actividades activadoras de receptores activados por proliferizador de peroxisomas gamma.Info
- Publication number
- MX2009006795A MX2009006795A MX2009006795A MX2009006795A MX2009006795A MX 2009006795 A MX2009006795 A MX 2009006795A MX 2009006795 A MX2009006795 A MX 2009006795A MX 2009006795 A MX2009006795 A MX 2009006795A MX 2009006795 A MX2009006795 A MX 2009006795A
- Authority
- MX
- Mexico
- Prior art keywords
- compounds
- angiotensin
- receptor antagonism
- activating activities
- ppary
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Se proporcionan compuestos de fórmula (I) que tienen tanto actividad antagonista de receptor de angiotensina II como actividad agonista de PPARy; (ver fórmula (I)) también se proporcionan composiciones farmacéuticas que comprenden los compuestos y procedimientos de tratamiento de enfermedades con los compuestos incluyendo diabetes tipo 2, resistencia a insulina, hiperinsulinemia, hiperlipidemia, hipertrigliceridemia, síndrome metabólico, fallo cardiaco congestivo, e hipertensión.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US87633406P | 2006-12-21 | 2006-12-21 | |
US97065307P | 2007-09-07 | 2007-09-07 | |
PCT/IB2007/003844 WO2008084303A1 (en) | 2006-12-21 | 2007-12-03 | Compounds having both angiotensin ii receptor antagonism and ppary activating activities |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2009006795A true MX2009006795A (es) | 2009-07-03 |
Family
ID=39284139
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2009006795A MX2009006795A (es) | 2006-12-21 | 2007-12-03 | Compuestos que tienen tanto actividades de antagonismo de receptor de angiotensina ii como actividades activadoras de receptores activados por proliferizador de peroxisomas gamma. |
Country Status (9)
Country | Link |
---|---|
US (1) | US20100029710A1 (es) |
EP (1) | EP2125806A1 (es) |
JP (1) | JP2010513457A (es) |
KR (1) | KR20090091356A (es) |
AU (1) | AU2007343139A1 (es) |
CA (1) | CA2671943A1 (es) |
MX (1) | MX2009006795A (es) |
NO (1) | NO20092374L (es) |
WO (1) | WO2008084303A1 (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPWO2010119700A1 (ja) | 2009-04-17 | 2012-10-22 | 興和株式会社 | 新規な3−ヘテロアリールピリミジン−4−(3h)−オン構造を有する化合物及びこれを含有する医薬 |
WO2010137336A1 (ja) | 2009-05-29 | 2010-12-02 | 興和株式会社 | 新規なα-フェノキシベンゼン酢酸誘導体及びこれを含有する医薬 |
EP2471782A4 (en) | 2009-08-27 | 2013-03-20 | Kowa Co | NEW SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME |
WO2011040004A1 (ja) | 2009-09-29 | 2011-04-07 | 興和株式会社 | 新規なフェニルピリジン誘導体及びこれを含有する医薬 |
CA2784710A1 (en) * | 2009-12-15 | 2011-06-23 | Shionogi & Co., Ltd. | Oxadiazole derivative having endothelial lipase inhibitory activity |
WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
DE102010015123A1 (de) | 2010-04-16 | 2011-10-20 | Sanofi-Aventis Deutschland Gmbh | Benzylamidische Diphenylazetidinone, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
KR20130122531A (ko) | 2010-05-24 | 2013-11-07 | 벤더르빌트 유니버시티 | Mglur5 양성 알로스테릭 조절물로서 치환된 6메틸니코틴아미드 |
US8933024B2 (en) | 2010-06-18 | 2015-01-13 | Sanofi | Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases |
US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
EP2687523B1 (en) | 2011-03-14 | 2016-01-06 | Kowa Company Ltd. | Novel phenylpyridine derivative and drug containing same |
ES2758841T3 (es) * | 2011-05-13 | 2020-05-06 | Celgene Int Ii Sarl | Moduladores heterocíclicos selectivos del receptor de la esfingosina-1-fosfato |
WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
WO2013045413A1 (en) | 2011-09-27 | 2013-04-04 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
WO2013068486A1 (en) | 2011-11-08 | 2013-05-16 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for the diagnosis and treatment of male infertility |
US9135515B2 (en) | 2012-10-22 | 2015-09-15 | Qiagen Gaithersburg, Inc. | Automated pelletized sample vision inspection apparatus and methods |
US9212976B2 (en) * | 2013-03-15 | 2015-12-15 | Qiagen Gaithersburg, Inc. | Vision-guided aspiration apparatus and methods |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5338740A (en) * | 1993-07-13 | 1994-08-16 | Pfizer Inc. | Angiotensin II receptor antagonists |
US20030158090A1 (en) * | 2001-07-23 | 2003-08-21 | Ulrik Pedersen-Bjergaard | Renin-angiotensin system in diabetes mellitus |
US7232828B2 (en) * | 2002-08-10 | 2007-06-19 | Bethesda Pharmaceuticals, Inc. | PPAR Ligands that do not cause fluid retention, edema or congestive heart failure |
-
2007
- 2007-12-03 CA CA002671943A patent/CA2671943A1/en not_active Abandoned
- 2007-12-03 US US12/518,472 patent/US20100029710A1/en not_active Abandoned
- 2007-12-03 KR KR1020097015282A patent/KR20090091356A/ko active IP Right Grant
- 2007-12-03 EP EP07849005A patent/EP2125806A1/en not_active Withdrawn
- 2007-12-03 JP JP2009542250A patent/JP2010513457A/ja not_active Withdrawn
- 2007-12-03 AU AU2007343139A patent/AU2007343139A1/en not_active Abandoned
- 2007-12-03 MX MX2009006795A patent/MX2009006795A/es unknown
- 2007-12-03 WO PCT/IB2007/003844 patent/WO2008084303A1/en active Application Filing
-
2009
- 2009-06-22 NO NO20092374A patent/NO20092374L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
US20100029710A1 (en) | 2010-02-04 |
AU2007343139A1 (en) | 2008-07-17 |
EP2125806A1 (en) | 2009-12-02 |
NO20092374L (no) | 2009-09-15 |
KR20090091356A (ko) | 2009-08-27 |
JP2010513457A (ja) | 2010-04-30 |
CA2671943A1 (en) | 2008-07-17 |
WO2008084303A1 (en) | 2008-07-17 |
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